Improved language model for French clinical reports achieves state-of-the-art performance in medical NLP tasks.
problem Lack of specialized language models for French clinical reports.
method Adapted a general pre-trained language model (CamemBERT) to French clinical reports using a corpus of 21M reports.
result Pretrained and fine-tuned models improved F1-score by 3 percentage points on APMed task.
CLARA generates clinical reports from raw inputs, improving accuracy and efficiency.
problem Generating accurate and detailed clinical reports from raw inputs is time-consuming and error-prone.
method Interactive method that generates reports sentence by sentence based on doctors' anchor words and partially completed sentences.
result CLARA achieves significant improvements in report generation accuracy and efficiency.
AI generates a sequence of death causes from hospital records.
problem Accurate death reporting for vital statistics and policy formulation.
method Neural machine translation models to generate causal chains, incorporating medical domain knowledge.
result Achieved 16.04 BLEU score for generating accurate causal chains.
Model uses unsupervised learning to classify medical reports with less labeled data.
problem Lack of labeled data for fine-grained disease classification in medical reports.
method Developed a pipeline combining an unsupervised encoder-language model and a supervised classifier model.
result Improved classification accuracy with less labeled data compared to previous methods.
Study develops a new algorithm for assessing clinical trial abstracts.
problem Limited tools for assessing qualitative statements in clinical research.
method Developed a three-class sentiment classification algorithm using BERT model.
result Algorithm achieved 91.3% classification accuracy and 0.92 macro F1-Score.
Qwant Research improves clinical case matching and information retrieval.
problem Matching and retrieving relevant clinical cases and discussions.
method Approach based on language models and preprocessings, information extraction system using neural networks and linguistic analysis.
result Very encouraging results in information extraction accuracy.
Representation learning improves EHR data for healthcare tasks.
problem Transforming EHR data into useful representations for machine learning.
method Deep learning and disentangling underlying factors from EHR data.
result Better representations improve machine learning performance in healthcare.
Deep learning model predicts CXR findings from patient scans.
problem Insufficient radiologists for accurate CXR interpretation.
method Tagged 959k studies, trained deep learning model on 2M reports.
result Model performs similarly to radiologists on 12 findings.
Gaussian Processes outperform other models in estimating uncertainty for radiology report observation detection.
problem Uncertainty quantification in automatic data labelling for semi-supervised learning in clinical NLP.
method Investigation of uncertainty estimates from various predictive models using NLPP and MMPCL metrics.
result Gaussian Processes provide superior performance in quantifying uncertainty for radiology report observation detection.
DreamNLP extracts important terms from EHRs using a modified Count Sketch algorithm.
problem Efficiently extracting information from large sets of EHRs with limited prior knowledge.
method Modified Count Sketch data streaming algorithm for low memory usage.
result Extracted terms are useful for defining important features for machine learning in precision medicine.
Stability in clinical prediction models is crucial for transferability between studies, yet has received little attention. The problem is paramount in high dimensional data which invites sparse models with feature selection capability. We introduce an effective method to stabilize sparse Cox model of time-to-events usi…
Biotech IPOs in Q1 2021: advanced degrees, clinical trials, and IP key.
problem Identifying traits of biotech startups that go public.
method Database of biotech IPOs, analysis of leadership, technology, clinical trials, and financing.
result Advanced degrees, clinical trials, and IP are important for biotech startups.
Automatically extracts phenotypes from cancer clinical notes for genetic studies.
problem Lack of structured patient representations in EHRs.
method Clustering of medical terms and sentences in clinical notes.
result 341 significant associations between clinical features and somatic mutations.
Supervised topic models can help clinical researchers find interpretable cooccurence patterns in count data that are relevant for diagnostics. However, standard formulations of supervised Latent Dirichlet Allocation have two problems. First, when documents have many more words than labels, the influence of the labels w…
System exposes study population descriptions in clinical guidelines.
problem Challenges in understanding applicability of clinical guidelines.
method Developed an ontology-enabled prototype system using SIO.
result Allows medical practitioners to better understand study populations.
MRI identifies chronic symptoms in mTBI patients.
problem Chronic symptoms in mTBI patients are hard to characterize.
method Multi-parametric MRI and low-dimensional projection.
result MRI metrics correlate with patient symptoms.
Method augments CTNs for ICD coding with neural network imputation.
problem Time-consuming manual annotation of CTNs for ICD coding.
method Semi-self-supervised neural network imputation of clinical features.
result Data augmentation improves ICD coding performance significantly.
Study examines impact of fairness penalties on clinical risk prediction models.
problem Widespread health disparities in machine learning-guided clinical decision-making.
method Empirical study across multiple databases, outcomes, and sensitive attributes.
result Penalizing fairness violations nearly universally degrades model performance and fairness metrics.
Study proposes a multimodal model for cardiovascular risk prediction using EHRs.
problem Lack of comprehensive risk prediction from EHRs due to unstructured text.
method Proposes a multimodal BiLSTM model integrating structured and unstructured EHR data.
result Proposed BiLSTM model outperforms other DNN architectures in cardiovascular risk prediction.
Multiple Sclerosis is a degenerative condition of the central nervous system that affects nearly 2.5 million of individuals in terms of their physical, cognitive, psychological and social capabilities. Researchers are currently investigating on the use of patient reported outcome measures for the assessment of impact a…
Paper presents an efficient method for selecting machine learning algorithms and hyper-parameters.
problem Efficient selection of machine learning algorithms and hyper-parameters is challenging for large datasets.
method Progressive sampling-based Bayesian optimization
result Significantly reduces search time, classification error rate, and error rate variability.
Antimicrobial resistance is an important public health concern that has implications in the practice of medicine worldwide. Accurately predicting resistance phenotypes from genome sequences shows great promise in promoting better use of antimicrobial agents, by determining which antibiotics are likely to be effective i…
Develops ML-DQA for healthcare data quality assurance.
problem Inconsistent use of real-world data in machine learning projects.
method Develops ML-DQA framework based on RWD best practices.
result Five generalizable practices emerge from ML-DQA implementation.
Unified Bayesian framework improves clinical trial hypothesis testing.
problem Lack of transparency and inability to quantify evidence in traditional P-values.
method Interval null hypothesis framework combined with Bayes factor-based tests.
result Bayesian interval hypothesis testing ensures frequentist error control and interpretability.
Machine learning guides clinicians in predictive modeling using big data.
problem Insufficient understanding of machine learning among clinicians hinders its adoption.
method Provides a series of guides on machine learning principles, resampling, model evaluation, and coding.
result Clinicians need methodological rigor and clarity to use machine learning effectively.
Study evaluates how framing affects machine learning models for sepsis prediction.
problem Understanding and reporting framing is crucial for AI technology success.
method Four different approaches applied to AI models of sepsis prediction.
result On-clinical-demand framing showed the lowest missing values and best temporal dependencies.
Infrastructure monitors AI/ML radiology models across multiple sites.
problem Monitoring and improving AI/ML radiology models across multiple sites.
method Interactive radiology reporting, centralized cloud system, post-marketing surveillance.
result Efficient monitoring and iterative development of AI/ML models without radiologist burden.
Detecting early signs of mood episodes in bipolar disorder patients.
problem Early identification of mood episodes in bipolar disorder patients for timely treatment.
method Signature-based model derived from stochastic analysis applied to real-time mood data.
result The signature method can identify the onset of mood episodes in bipolar disorder patients.
Transformers improve Alzheimer's disease progression prediction by accounting for irregular biomarker histories.
problem Difficult prediction of medium-horizon Alzheimer's disease progression due to tied clinical scores and irregular biomarker observations.
method Developed a residual gap-aware transformer that combines statistical reference with transformer-based residual learning.
result The proposed model reduces mean error and improves prediction-observation correlation compared to baseline models.
This review explores automated pain detection from facial expressions using FACS.
problem Automated detection of pain from facial expressions is challenging and underexplored.
method Examines progress in AFER and APD, focusing on FACS-based methods and deep learning.
result Limited studies on APD, highlighting the need for clinical applications.
Proposes isotonic regression for calibrating Deep Cox models' survival probabilities.
problem Poor calibration of Deep Cox models' survival probabilities.
method Isotonic regression for post hoc calibration of Deep Cox models.
result Establishes favorable theoretical guarantees and demonstrates empirical effectiveness.
Personalized models using group attributes reduce performance, study finds.
problem Reducing performance of models using group attributes like race or gender.
method Formal conditions and collective preference guarantees to ensure fair use.
result Models personalized with group attributes reduce performance at a group level.
Expands statistical background for knee osteoarthritis treatment models.
problem Developing optimal exercise and weight loss treatments for knee osteoarthritis.
method Precision medicine models and jackknife cross-validation method.
result Jackknife estimator provides consistent value function estimation.
Study validates machine learning models for patient outcomes using various methods.
problem Validating machine learning models for patient outcomes in electronic health records.
method Used three state-of-the-art machine learning methods (random forest, gradient boosting, logistic regression) to predict patient outcomes and assess feature importance.
result Permutation tests applied to random forest and gradient boosting models showed the most agreement with clinical interpretation of feature importance.
ROOFS helps researchers select robust biomarker features from complex data.
problem Challenges in feature selection for biomarker discovery and clinical models.
method ROOFS is a Python package that benchmarks multiple feature selection methods on user data.
result ROOFS identifies a filter method as optimal for identifying predictors of lung cancer resistance.
Paper uses ML to classify liver diseases from clinical data.
problem Classifying liver diseases from clinical data.
method Multiple imputation, PCA, data visualizations, binary classifier algorithms (ANN, RF, SVM).
result SVM showed better accuracy (98.23%).
Study uses ML to predict HL survival, outperforming CoxPH.
problem Improving survival prediction for HL patients.
method Compared multiple ML algorithms to CoxPH model.
result ML models outperform CoxPH in predicting HL survival.
Method predicts ODX scores for breast cancer patients based on clinical data.
problem Predicting ODX scores for breast cancer patients to aid decision-making.
method Distributional random forest approach using 9 clinico-pathological characteristics.
result Correctly predicted 92% of low risk and 40.2% of high risk patients.
Enhanced mortality prediction model using EHR and free-text data.
problem Predicting one-year mortality in AMI patients.
method Used deep learning models with word embedding features from free-text discharge summaries.
result Significant improvement in model performance (92.89% accuracy, 0.928 F-measure).
Improved radiological abnormality detection using LSTM with time-modulated approach.
problem Detect radiological abnormalities in medical images using CNNs on individual exams.
method Used time-modulated LSTM to model entire sequence of radiographs, including reports.
result Improved detection of radiological abnormalities on chest x-rays.
Machine learning classifies septic vs. non-septic microcirculation images with high accuracy.
problem Automated diagnosis of sepsis using microcirculation imaging.
method Machine learning classifier trained on dark field microcirculation videos.
result Classifier achieves 89.45% accuracy and 0.92 AUC.
Neural SDEs model suicide risk with compact state space constraints.
problem Modeling suicide risk with irregular, noisy, and partially observed data.
method Developed neural SDEs confined to compact state spaces, addressing domain constraints and numerical stability.
result Improved forecasts and optimization dynamics over standard models on EMA datasets.
Custom NLP system extracts clinical data for breast cancer analysis.
problem Manual extraction of information from text-based medical records is tedious and requires specialized knowledge.
method Combines standard text mining techniques with advanced synonym detection for global analysis.
result Achieved good extraction accuracy for various concepts of interest without requiring existing corpora or ontologies.
The incidence of malignant melanoma continues to increase worldwide. This cancer can strike at any age; it is one of the leading causes of loss of life in young persons. Since this cancer is visible on the skin, it is potentially detectable at a very early stage when it is curable. New developments have converged to ma…
Machine learning identifies potential drugs for COVID-19.
problem Finding effective treatments for COVID-19.
method Trained neural network models on virus protein sequences and antiviral drugs.
result Identified potential drug candidates for treating COVID-19.
The study evaluates AI model performance measures for medical use.
problem Selecting appropriate performance measures for AI models in medical practice.
method Assessed 32 performance measures across five domains for binary outcomes.
result 17 measures are both proper and reflect decision-analytic performance.
Deep learning predicts readmissions from less structured data.
problem Predicting readmissions from non-standard, unstructured medical records.
method Proposes a deep learning architecture that handles less structured data, including Spanish text.
result Achieves AUROC of 0.76 on a Chilean medical dataset, comparable to US results.
We present a novel method for variable selection in regression models when covariates are measured with error. The iterative algorithm we propose, MEBoost, follows a path defined by estimating equations that correct for covariate measurement error. Via simulation, we evaluated our method and compare its performance to …