Deep learning for integrating diverse clinical measurements.
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AdaptiveNet tackles disease progression prediction in rheumatoid arthritis using deep neural networks.
DRUM transfers cardiac arrest models across registries with missing covariates.
Causal ML predicts treatment outcomes, aiding personalized medicine.
In order to investigate the breast cancer prediction problem on the aging population with the grades of DCIS, we conduct a tree augmented naive Bayesian network experiment trained and tested on a large clinical dataset including consecutive diagnostic mammography examinations, consequent biopsy outcomes and related can…
Interventional cancer clinical trials are generally too restrictive, and some patients are often excluded on the basis of comorbidity, past or concomitant treatments, or the fact that they are over a certain age. The efficacy and safety of new treatments for patients with these characteristics are, therefore, not defin…
FRESH combines patient-level and aggregate-level data for better clinical decision making.
Objectives: Most cancer data sources lack information on metastatic recurrence. Electronic medical records (EMRs) and population-based cancer registries contain complementary information on cancer treatment and outcomes, yet are rarely used synergistically. To enable detection of metastatic breast cancer (MBC), we appl…
Improves trial efficiency by adjusting for historical prognostic scores.
The size distribution of land plots is a result of land allocation processes in the past. In the absence of regulation this is a Markov process leading an equilibrium described by a probabilistic equation used commonly in the insurance and financial mathematics. We support this claim by analyzing the distribution of tw…
Comorbid diseases co-occur and progress via complex temporal patterns that vary among individuals. In electronic health records we can observe the different diseases a patient has, but can only infer the temporal relationship between each co-morbid condition. Learning such temporal patterns from event data is crucial f…
Hidden Markov jump processes are an attractive approach for modeling clinical disease progression data because they are explainable and capable of handling both irregularly sampled and noisy data. Most applications in this context consider time-homogeneous models due to their relative computational simplicity. However,…
The public package registry npm is one of the biggest software registry. With its 216 911 software packages, it forms a big network of software dependencies. In this paper we evaluate various methods for finding similar packages in the npm network, using only the structure of the graph. Namely, we want to find a way of…
WEST uses EHRs and expert cases to improve rare disease phenotyping.
Study examines cryptoasset service providers in Austria, revealing global integration and distinct responses to market shocks.
Study uses machine learning to analyze patient survey data for Lyme disease.
Joint Models for longitudinal and time-to-event data have gained a lot of attention in the last few years as they are a helpful technique to approach common a data structure in clinical studies where longitudinal outcomes are recorded alongside event times. Those two processes are often linked and the two outcomes shou…
This paper presents the first deep reinforcement learning (DRL) framework to estimate the optimal Dynamic Treatment Regimes from observational medical data. This framework is more flexible and adaptive for high dimensional action and state spaces than existing reinforcement learning methods to model real-life complexit…
Missing values challenge data analysis because many supervised and unsupervised learning methods cannot be applied directly to incomplete data. Matrix completion based on low-rank assumptions are very powerful solution for dealing with missing values. However, existing methods do not consider the case of informative mi…
Agent-to-agent finance aims to manage payments and trust for AI agents.
We present in this paper experiments on Table Recognition in hand-written registry books. We first explain how the problem of row and column detection is modeled, and then compare two Machine Learning approaches (Conditional Random Field and Graph Convolutional Network) for detecting these table elements. Evaluation wa…
SYNTHONY selects tabular synthesizers based on stress profiling and user intent.
Deep learning models can infer individual trajectories from sparse data.
The paper predicts diseases using both clinical and genomics data.
Clinical notes contain a large amount of clinically valuable information that is ignored in many clinical decision support systems due to the difficulty that comes with mining that information. Recent work has found success leveraging deep learning models for the prediction of clinical outcomes using clinical notes. Ho…
Clinical AI models fail to transfer between sites due to site-specific practices.
System suggests clinical concepts in real-time for faster note creation.
We introduce SparseVM, a method that registers clinical-quality 3D MR scans both faster and more accurately than previously possible. Deformable alignment, or registration, of clinical scans is a fundamental task for many clinical neuroscience studies. However, most registration algorithms are designed for high-resolut…
AI predicts medical specialty diagnostic choices from EHR records.
Novel metrics improve machine learning models for ICU patient care.
Machine learning predicts patient recruitment for clinical trials.
Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand irregular clinical event sequences. We make the observation that clinical events at a…
With the maturation of metabolomics science and proliferation of biobanks, clinical metabolic profiling is an increasingly opportunistic frontier for advancing translational clinical research. Automated Machine Learning (AutoML) approaches provide exciting opportunity to guide feature selection in agnostic metabolic pr…
Skin cancer is one of the most common types of cancer around the world. For this reason, over the past years, different approaches have been proposed to assist detect it. Nonetheless, most of them are based only on dermoscopy images and do not take into account the patient clinical information. In this work, first, we …
Study develops a new algorithm for assessing clinical trial abstracts.
Improved negation detection in Dutch clinical texts using machine learning.
The paper explores using historical data to improve clinical trial analysis by optimizing covariate weights.
Alzheimer's disease (AD) is a degenerative brain disease impairing a person's ability to perform day to day activities. The clinical manifestations of Alzheimer's disease are characterized by heterogeneity in age, disease span, progression rate, impairment of memory and cognitive abilities. Due to these variabilities, …
Study examines biases in clinical word embeddings, revealing performance gaps across groups.
Study improves healthcare time series imputation by considering structured missingness.
New method detects biomarker-treatment interactions in clinical trials.
In this chapter, we provide a brief overview of applying machine learning techniques for clinical prediction tasks. We begin with a quick introduction to the concepts of machine learning and outline some of the most common machine learning algorithms. Next, we demonstrate how to apply the algorithms with appropriate to…
Improved language model for French clinical reports achieves state-of-the-art performance in medical NLP tasks.
The recent adoption of Electronic Health Records (EHRs) by health care providers has introduced an important source of data that provides detailed and highly specific insights into patient phenotypes over large cohorts. These datasets, in combination with machine learning and statistical approaches, generate new opport…
Late fusion of clinical notes and physiological data improves ICU mortality prediction.
Deep learning analyzes healthcare provider actions and patient outcomes.
Discusses handling intercurrent events in clinical trials with time-to-event outcomes.
Clinical forecasting based on electronic medical records (EMR) can uncover the temporal correlations between patients' conditions and outcomes from sequences of longitudinal clinical measurements. In this work, we propose an intervention-augmented deep state space generative model to capture the interactions among clin…