Big data analytics improves healthcare through early detection and quality life.
problem Limited access to healthcare data hinders evidence-based decision-making.
method Analysis of healthcare data using various tools and techniques.
result Big data analytics enhances healthcare quality and patient outcomes.
Proposes a deep learning framework for evaluating patient similarities from EHRs.
problem Evaluating clinical similarities between patients for various healthcare applications.
method A deep learning framework with medical concept embedding, preserving temporal information.
result Significant improvement in patient similarity evaluation over baselines.
The past decade has seen an explosion in the amount of digital information stored in electronic health records (EHR). While primarily designed for archiving patient clinical information and administrative healthcare tasks, many researchers have found secondary use of these records for various clinical informatics tasks…
New method discovers useful structure in multi-view data for clinical applications.
problem Detecting slow bleeding in patients monitored for central venous pressure.
method Proposes a method to characterize globally nonlinear multi-view relationships using a mixture of linear relationships.
result Demonstrates the potential to find useful structure in data that is hard to find with single-view or current multi-view methods.
ConCare personalizes healthcare predictions by capturing EMR features.
problem Predicting patient outcomes from EMR data with personalization.
method Captures personal characteristics and time-aware distribution in EMR data.
result Improves healthcare prediction accuracy through personalized health context.
Deep learning predicts ICD codes with high accuracy for patient phenotyping.
problem Variability in ICD code assignment by coders.
method Deep learning model trained on demographics, lab results, and medications.
result Model predictions outperform coder assigned ICD codes in accuracy.
A machine learning model improves MV CDSS accuracy.
problem Limited input data for MV CDSS due to missing physiologic monitoring device information.
method Developed a machine learning classifier for 5 MV modes with high accuracy.
result Average F1-score of 97.52% for per-breath classification.
Geotechnics adopts data-driven methods from materials informatics.
problem Soil complexity and lack of comprehensive data.
method Leveraging deep learning and transfer learning for feature extraction.
result Revolutionary potential of advanced computational tools in geotechnics.
ME2Vec learns medical entity vectors from EHR data.
problem Learning structured information from EHR data.
method Graph-based medical entity embedding using diverse graph embedding techniques.
result ME2Vec outperforms baselines in disease diagnosis prediction.
In this paper are presented methods of impact analysis on informatics system security accidents, qualitative and quantitative methods, starting with risk and informational system security definitions. It is presented the relationship between the risks of exploiting vulnerabilities of security system, security level of …
Paper proposes a framework to predict therapeutic properties of compounds.
problem Predict therapeutic properties of compounds with heterogeneous data.
method Domain-adversarial multi-task framework using adversarial learning.
result Framework improves performance over competitive baselines.
PiNet improves graph classification efficiency and accuracy.
problem Graph level classification challenges.
method Attention-based pooling mechanism for graph convolution operations.
result Superior performance and high sample efficiency.
SFM generates smooth functional data without exposing real data.
problem Challenges in statistical analysis of functional data.
method Copula framework and smooth flow construction.
result SFM produces high-quality synthetic functional data.
AI improves healthcare diagnostics and predictions.
problem Data heterogeneity and model limitations in AI for health.
method Review of AI applications in health informatics.
result AI enhances disease diagnosis and prediction.
AI generates a sequence of death causes from hospital records.
problem Accurate death reporting for vital statistics and policy formulation.
method Neural machine translation models to generate causal chains, incorporating medical domain knowledge.
result Achieved 16.04 BLEU score for generating accurate causal chains.
The portfolio optimization problem in which the variances of the return rates of assets are not identical is analyzed in this paper using the methodology of statistical mechanical informatics, specifically, replica analysis. We define two characteristic quantities of an optimal portfolio, namely, minimal investment ris…
Modeling territorial control in civil wars using HMMs.
problem Lack of fine-grained data on territorial control in civil wars.
method Theoretical model of territorial control and Hidden Markov Models (HMMs).
result HMMs can estimate levels of territorial control in civil wars.
Deep learning model explains breast cancer subtypes using logistic regression.
problem Clarifying the mechanisms of breast cancer subtypes for better treatment.
method Developed a PWL model that generates custom-made logistic regression for each patient.
result The PWL model reveals genes relevant to cell cycle-related pathways.
Paper proposes active learning for structured output design, improving Gaussian process model predictions.
problem Finding optimal input parameters for achieving desired structured outputs.
method Developed new acquisition functions to minimize prediction error of Gaussian process model, incorporating output correlations.
result Effectiveness demonstrated in synthetic and real data experiments, including materials informatics.
Deep learning method extracts medical knowledge from YouTube videos.
problem Improving healthcare information dissemination through machine learning.
method Developed a deep learning method to classify YouTube videos by medical knowledge level.
result Preliminary results show satisfactory performance in extracting medical knowledge from videos.
Multitask learning improves phenotyping in EHR data, but its benefits vary by phenotype complexity.
problem Improving phenotyping accuracy in EHR data using multitask learning.
method Investigated multitask learning for phenotyping rare and common phenotypes in EHR data using neural nets and logistic regression.
result Multitask learning with neural nets consistently outperforms single-task neural nets for rare phenotypes but underperforms for common phenotypes.
Develops robust learning framework under distributional perturbations.
problem Learning robust to data distributional changes.
method Distributionally Robust Optimization (DRO) under Wasserstein metric.
result Establishes performance guarantees and tractable formulations.
Paper finds previous work on submanifolds incorrect.
problem Incorrect definition of semi-invariant submanifolds.
method Examined previous work's definition and found it flawed.
result Previous results on semi-invariant submanifolds are invalid.
Transfer learning improves model accuracy on sparse materials datasets.
problem Irreducible errors in analyses due to differing measurements across datasets.
method Three transfer learning techniques: multi-task, difference, and explicit latent variable architectures.
result Explicit latent variable method is most accurate for activation energies of NO reduction steps.
Review of automatic de-identification systems for EHR, highlighting challenges beyond accuracy.
problem Challenges in surrogate generation and patient privacy in de-identification of EHR.
method Comprehensive review of 18 recently published systems, focusing on accuracy and challenges.
result Despite accuracy improvements, challenges remain in surrogate generation and patient privacy.
With different genomes available, unsupervised learning algorithms are essential in learning genome-wide biological insights. Especially, the functional characterization of different genomes is essential for us to understand lives. In this book chapter, we review the state-of-the-art unsupervised learning algorithms fo…
The paper predicts diseases using both clinical and genomics data.
problem Clinical predictions using genomics data are not common.
method Integrated clinical and genomics datasets, machine learning, Principal Component Analysis for feature selection.
result 73% accuracy in predicting 75 disease classes.
Improved model predicts ICU readmission and mortality with interpretable results.
problem Lack of clinically interpretable predictions from deep learning models on clinical notes.
method Augmented a convolutional model with an attention mechanism for clinical note prediction.
result Attention mechanism improves prediction performance while providing interpretable results.
SparseVM registers clinical 3D scans faster and more accurately.
problem Inaccurate and slow registration of sparse clinical 3D scans.
method Learning-based registration method tailored for clinical sparse MRI.
result Orders of magnitude faster and more accurate than existing methods.
Clinical AI models fail to transfer between sites due to site-specific practices.
problem Clinical AI models perform poorly at new sites.
method Identify and isolate site-specific clinical practices affecting data distribution.
result A potential solution to improve model transferability.
Model learns hierarchical EHR representation for clinical outcome prediction.
problem Capturing temporal patterns in irregular clinical event sequences.
method Proposes differentiated mechanisms to model events at different time scales, learning hierarchical representations.
result Significantly improves clinical outcome prediction, achieving AUC scores of 0.94 and 0.90 for death and ICU admission respectively.
System suggests clinical concepts in real-time for faster note creation.
problem Efficiently creating structured clinical notes with minimal keystrokes.
method Contextual autocompletion using shallow neural networks.
result Reduces keystrokes by 67% in real hospital environments.
AutoML enhances clinical metabolic profiling by adjusting for confounders.
problem Identifying and adjusting for clinical confounders in AutoML for metabolic profiling.
method Tandem rank-accuracy measure for feature selection, residual training adjustment for confounders.
result Increased homocysteine concentration associated with long-term metformin exposure.
Machine learning aids in clinical prediction tasks.
problem Improving accuracy in clinical predictions.
method Introduction to machine learning concepts and algorithms, followed by practical application to clinical datasets.
result Demonstrated the application of machine learning models to clinical prediction problems.
Novel metrics improve machine learning models for ICU patient care.
problem Predicting vital sign trajectories for early detection of adverse events.
method Developed novel performance metrics aligned with clinical contexts, validated on simulated and real datasets, and optimized neural networks using these metrics.
result Neural networks trained with these metrics excel in predicting clinically significant events.
AI predicts medical specialty diagnostic choices from EHR records.
problem Predicting timely medical specialty diagnostic workups for patients.
method Ensemble of feed-forward neural networks trained on EHR data.
result Significantly higher accuracy compared to traditional checklists.
Machine learning predicts patient recruitment for clinical trials.
problem Improving patient recruitment prediction for clinical trials.
method Machine learning methods applied to historical clinical trial data.
result Reduced prediction error compared to current industry standards.
Paper tackles investment risk with cost and return constraints using replica analysis.
problem Investment risk minimization under cost and return constraints.
method Replica analysis for portfolio optimization problems.
result Derivation of macroscopic theory for optimal solution.
GANs help create realistic synthetic health data, boosting medical research.
problem Challenges in creating realistic synthetic health data due to private patient data.
method Generative Adversarial Networks (GANs) to learn and produce synthetic health data.
result GANs can produce realistic synthetic health data, overcoming challenges in OHD.
New dataset and approach improve skin cancer detection accuracy.
problem Lack of patient clinical information in automated skin cancer detection.
method Introduced a new dataset with clinical images and patient information. Combined clinical data with dermoscopy images using deep learning models.
result Combining clinical data improves skin cancer detection accuracy by around 7%.
Automatically extracts phenotypes from cancer clinical notes for genetic studies.
problem Lack of structured patient representations in EHRs.
method Clustering of medical terms and sentences in clinical notes.
result 341 significant associations between clinical features and somatic mutations.
Survey on DRL for clinical decision support.
problem Improving clinical decision-making through AI.
method Deep reinforcement learning with DNN.
result Survey and comparison of DRL algorithms in clinical applications.
We apply information-based complexity analysis to support vector machine (SVM) algorithms, with the goal of a comprehensive continuous algorithmic analysis of such algorithms. This involves complexity measures in which some higher order operations (e.g., certain optimizations) are considered primitive for the purposes …
A clinical Meta-Dataset from TCGA for multi-task learning.
problem Clinical decision making requires considering multiple factors; current benchmarks lack consistency and variety.
method Developed a Meta-Dataset with 174 tasks from TCGA, using regression and neural networks.
result Demonstrated the feasibility of predicting multiple clinical variables from gene expression data.
Study develops a new algorithm for assessing clinical trial abstracts.
problem Limited tools for assessing qualitative statements in clinical research.
method Developed a three-class sentiment classification algorithm using BERT model.
result Algorithm achieved 91.3% classification accuracy and 0.92 macro F1-Score.
Improved negation detection in Dutch clinical texts using machine learning.
problem Extracting negation from clinical text for better model development.
method Comparison of rule-based and machine learning methods (biLSTM, RoBERTa).
result BiLSTM and RoBERTa models outperform rule-based method in F1 score, precision, and recall.
This research uses machine learning to identify Alzheimer's disease subtypes and predict progression.
problem Heterogeneity in Alzheimer's disease clinical manifestations and progression rate limit personalized care and treatment planning.
method Unsupervised and supervised machine learning approaches applied to ADNI data.
result Identification of patient subtypes and prediction of disease progression zones.
Paper introduces a new measure combining entropy and Gini index.
problem Quantifying complexity in socio- and econo-physics.
method Generalizes entropy using Gini index and Lorenz curve transformation.
result Supports quantifying complexity in socio- and econo-physics.