Study quantifies motion dynamics of ankle sprains using biosensor data.
problem Diagnosing chronic ankle instability (CAI) based on objective biomechanical measures.
method Developed a nonlinear subspace clustering method to learn motion patterns from multi-joint coordination.
result Classification accuracy of >70% on CAI vs. normal controls using leave-one-subject-out cross validation.
A typical problem in causal modeling is the instability of model structure learning, i.e., small changes in finite data can result in completely different optimal models. The present work introduces a novel causal modeling algorithm for longitudinal data, that is robust for finite samples based on recent advances in st…
Deep learning system tracks stool consistency for GI disease assessment.
problem Lack of objective stool consistency measurements in chronic GI disease.
method Computer vision and deep convolutional neural networks (CNN).
result Developed a stool detection and tracking system.
Proposes a new model for predicting chronic conditions over time.
problem Predicting complex relationships between multiple chronic conditions.
method Continuous time Bayesian network with adaptive regularization for structure and parameter learning.
result Proposed model provides sparse, intuitive representation of chronic condition relationships.
Chronicals boosts LLM fine-tuning speed by 3.51x over Unsloth.
problem Memory bottleneck in fine-tuning large language models.
method Four optimizations: fused kernels, cross-entropy reduction, LoRA+, and sequence packing.
result 3.51x speedup on A100-40GB with Qwen2.5-0.5B.
MRI identifies chronic symptoms in mTBI patients.
problem Chronic symptoms in mTBI patients are hard to characterize.
method Multi-parametric MRI and low-dimensional projection.
result MRI metrics correlate with patient symptoms.
Simulation framework assesses ROI of chronic disease adherence and policy timing.
problem Uncertainty in ROI of adherence-enhancing interventions under heterogeneous patient behavior and socioeconomic variation.
method Simulation-based framework integrating disease progression, time-varying adherence, and policy timing.
result Early and adaptive interventions yield highest ROI, exceeding 20% under certain conditions.
New fair regression method improves fairness in chronic kidney disease classification.
problem Mitigating societal bias in health care for multiple groups.
method Penalized fair regression framework for multiple groups, with penalties for true positive rate disparity.
result Achieves fairness-accuracy frontier beyond existing methods in simulations and real-world data.
Enhances generative model for clinical data privacy and accuracy.
problem Data privacy in electronic patient records.
method Improves a time-series generative model with privacy safeguards.
result DP-TimeGAN achieves a mean authenticity of 0.778 on the CKD dataset.
Study uses machine learning and survival analysis to predict CKD progression.
problem Early detection and management of CKD to reduce ESRD risk.
method Combines machine learning and classical statistical models to identify novel CKD progression predictors.
result Deep learning models outperform other methods in predicting CKD progression.
Novel framework detects CKD in diabetic patients using sparse EHR representations.
problem Early detection of CKD in diabetic patients.
method Sparse longitudinal representations of EHR data.
result Proposed model achieves higher predictive performance than baselines.
GWN improves multimodal data fusion accuracy for chronic pain patients.
problem Dynamic and unspecified uncertainties in multimodal data fusion.
method Inspired by Global Workspace Theory, GWN is a neural network architecture that dynamically attends to multiple modalities.
result GWN achieved higher F1 scores (0.92 and 0.75) for multimodal discrimination and classification tasks.
Machine learning predicts obesity causes using genetic and imaging data.
problem Predicting causes of obesity in children and adults.
method Use ML techniques like decision trees, SVM, RF, GBM, LASSO, BN, and ANN on genetic and imaging data.
result ML models accurately predict obesity causes and chronic diseases.
Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is not always a single readily available biomarker to quantify disease severity. Eve…
In this work we investigate intra-day patterns of activity on a population of 7,261 users of mobile health wearable devices and apps. We show that: (1) using intra-day step and sleep data recorded from passive trackers significantly improves classification performance on self-reported chronic conditions related to ment…
DPVis integrates HMMs into visualizations for disease progression analysis.
problem Challenges in interpreting HMMs for disease progression modeling.
method Design study with clinical experts, visualizations of HMM parameters and outcomes.
result DPVis successfully evaluates and summarizes disease progression models.
Deep learning predicts drug prescriptions across global health records.
problem Predicting drug prescriptions in chronic disease patients.
method Adaptive cross-global attention graph kernel network with support vector machine.
result Model outperforms current methods in accuracy and interpretability.
Deep learning detects protective movement behavior in chronic pain patients.
problem Detecting protective movement behavior in chronic pain patients for intervention.
method End-to-end deep learning architecture named BodyAttentionNet (BANet) that learns temporal and bodily parts.
result Statistically significant improvements in detecting protective behavior using attention mechanisms.
We improve current instability-based methods for the selection of the number of clusters k in cluster analysis by developing a normalized cluster instability measure that corrects for the distribution of cluster sizes, a previously unaccounted driver of cluster instability. We show that our normalized instability mea…
RL algorithms with medical integration improve personalized treatment recommendations.
problem Developing effective personalized treatment strategies for chronic diseases.
method Integrating medical knowledge into RL algorithms for DTR.
result Enhanced treatment recommendations with increased confidence.
We study the behavior of a Time-Aware Long Short-Term Memory Autoencoder, a state-of-the-art method, in the context of learning latent representations from irregularly sampled patient data. We identify a key issue in the way such recurrent neural network models are being currently used and show that the solution of the…
Paper learns versatile balancing and recovery motions for humanoid robots.
problem Training humanoid robots to handle unexpected perturbations.
method Hierarchical Deep Reinforcement Learning in a physics simulator.
result Learned skills comparable to preprogrammed controllers but more adaptable.
Modeling HFT interactions reveals market instability.
problem Market instability caused by HFT dynamic coupling.
method Developed a recurrence relations framework to model HFT interactions.
result Unexpected latency and feedback can trigger market instability.
New proof of instability for certain Einstein metrics.
problem Einstein metrics on specific 4-manifolds.
method Proving instability of conformally Kähler, Einstein metrics.
result Proven instability of certain Einstein metrics.
Study stability and instability of Ricci-flat metrics under generalized Ricci flow.
problem Stability and instability of Ricci-flat metrics under Ricci flow.
method Analysis of generalized Ricci flow for Ricci-flat metrics and vanishing 3-forms.
result Dynamical stability and instability results for Ricci-flat metrics and vanishing 3-forms.
Some exotic compact objects possess evanescent ergosurfaces: timelike submanifolds on which a Killing vector field, which is timelike everywhere else, becomes null. We show that any manifold possessing an evanescent ergosurface but no event horizon exhibits a linear instability of a peculiar kind: either there are solu…
Smart bin monitors predict medication adherence with high accuracy.
problem Predicting chronic medication adherence to improve healthcare efficiency.
method Machine learning models trained on IoT device data.
result High predictive performance (ROC AUC 0.86).
Interval Neural Networks detect instabilities in image reconstructions.
problem Detecting instabilities in deep learning image reconstructions.
method Employed uncertainty quantification methods with Interval Neural Networks.
result Interval Neural Networks effectively reveal image reconstruction instabilities.
Note on instabilities in super-time-stepping methods for Heston model.
problem Instabilities in super-time-stepping methods applied to Heston model.
method Exploration of explicit super-time-stepping schemes (RK-Chebyshev, RK-Legendre) for Heston model.
result Relevance of stability remarks beyond super-time-stepping schemes.
Causal modeling has long been an attractive topic for many researchers and in recent decades there has seen a surge in theoretical development and discovery algorithms. Generally discovery algorithms can be divided into two approaches: constraint-based and score-based. The constraint-based approach is able to detect co…
The paper explores how word embeddings affect the stability of downstream NLP models.
problem Small changes in training data can cause significant changes in model predictions.
method Empirical and theoretical analysis of embedding instability, including the introduction of eigenspace instability measure.
result Increasing embedding memory can reduce the disagreement in predictions by 5% to 37%.
In the presence of a layer of metaprobabilities (from uncertainty concerning the parameters), the asymptotic tail exponent corresponds to the lowest possible tail exponent regardless of its probability. The problem explains "Black Swan" effects, i.e., why measurements tend to chronically underestimate tail contribution…
Binary perceptron's instability linked to replica symmetry breaking.
problem Understanding the relationship between algorithmic instability and replica symmetry breaking in binary perceptron learning.
method Established the connection between algorithmic instability and replica symmetry breaking by comparing the instability condition around the fixed point to the instability for breaking the replica symmetric solution of the free energy function.
result The instability condition around the algorithmic fixed point is identical to the instability for breaking the replica symmetric saddle point solution of the free energy function.
A central area of research in nonlinear science is the study of instabilities that drive the emergence of extreme events. Unfortunately, experimental techniques for measuring such phenomena often provide only partial characterization. For example, real-time studies of instabilities in nonlinear fibre optics frequently …
StageNet improves health risk prediction by integrating disease stage information.
problem Improving health risk prediction for patients with chronic conditions.
method StageNet uses a stage-aware LSTM and stage-adaptive convolutional modules to extract and integrate disease stage information.
result StageNet achieves up to 12% higher AUPRC for risk prediction and over 58% higher Calinski-Harabasz score for patient subtyping compared to state-of-the-art models.
Develops a geometric framework for soap film instabilities.
problem Soap film instabilities on minimal surfaces.
method Björling representation of minimal surfaces.
result Jacobi fields are maximally localized with lowest eigenfunction amplitude.
Model predicts treatment initiation from clinical data using patient-clinician relations.
problem Predicting treatment initiation from clinical time series data considering patient-clinician relations.
method Graph-Augmented Time-Sensitive Model using top eigenvectors of graph Laplacian.
result Relational similarity improves prediction over baselines, e.g., 5% improvement in AUPRC.
Study reviews machine learning techniques for stress monitoring.
problem Improving accuracy of stress monitoring devices.
method Reviewed machine learning techniques for various stress indicators.
result Choosing the right classifier depends on multiple factors.
The study examines stability and instability of Poincaré-Einstein metrics using Ricci flow.
problem Stability and instability of Poincaré-Einstein metrics.
method Variant of expander entropy for asymptotically hyperbolic manifolds, local positive mass theorem, volume comparison.
result Characterization of stability and instability in terms of local positive mass theorem and volume comparison.
Study shows instability of naked singularities in perfect fluid models.
problem Instability of naked singularities in Einstein equations coupled with isothermal perfect fluid.
method Investigated spherically symmetric self-similar naked singularities under C1,α perturbations of an external massless scalar field. result Spherically symmetric self-similar naked singularities are unstable to trapped surface formation.
Study on spectral stability of Riemannian coverings.
problem Stability of eigenvalues in Riemannian coverings.
method Analysis of Laplacian eigenvalues under finite coverings.
result Necessary conditions for spectral stability or instability.
Clinical models can be unstable, leading to unreliable predictions.
problem Stability of clinical prediction models developed using statistical or machine learning methods.
method Simulation and case studies of statistical and machine learning approaches to show instability in model predictions.
result Model instability often leads to miscalibration of predictions in new data.
A data-driven approach predicts morphological development under structural instability.
problem Understanding and predicting spatiotemporal complexities of morphogenesis under structural instability.
method Machine-learning framework based on physical modeling of morphogenesis.
result Identification of key bifurcation characteristics and prediction of history-dependent development.
Mapper instability quantified for robust graph construction.
problem Variability in Mapper output due to parameter selection.
method Defined an intrinsic instability measure for Mapper outputs.
result Identified local minima of instability for reliable outputs.
Study shows instability of naked singularities in scalar field models.
problem Stability of naked singularities in spherically symmetric Einstein-Scalar field systems.
method Analysis of a family of incoming null cones becoming increasingly singular.
result Naked singularities are unstable to black hole formation under certain perturbations.
Study shows instability of certain MOTSs with continuous symmetry.
problem Stability of MOTSs with continuous symmetry.
method Analysis of initial data sets with continuous symmetry and non-preserved MOTSs.
result Exotic MOTSs are unstable except in exceptional cases.
Sufficient physical activity and restful sleep play a major role in the prevention and cure of many chronic conditions. Being able to proactively screen and monitor such chronic conditions would be a big step forward for overall health. The rapid increase in the popularity of wearable devices provides a significant new…
This paper develops explainable treatment policies for RPM using clinical knowledge.
problem Barriers to adoption of DHIs and lack of interpretability in purely black-box algorithms.
method Developed a pipeline for learning explainable treatment policies using clinician-informed representations.
result Policies learned from clinician-informed representations are more efficacious and efficient than black-box policies.