Study classifies pathology reports using TF-IDF features and machine learning.
problem Classifying pathology reports for cancer surveillance and diagnostic workflow.
method Extracted TF-IDF features from pathology reports and classified them using SVM, XGBoost, and Logistic Regression.
result XGBoost achieved 92% accuracy in classifying pathology reports.
Objectives: Most cancer data sources lack information on metastatic recurrence. Electronic medical records (EMRs) and population-based cancer registries contain complementary information on cancer treatment and outcomes, yet are rarely used synergistically. To enable detection of metastatic breast cancer (MBC), we appl…
We have applied a little-known data transformation to subsets of the Surveillance, Epidemiology, and End Results (SEER) publically available data of the National Cancer Institute (NCI) to make it suitable input to standard machine learning classifiers. This transformation properly treats the right-censored data in the …
New method tackles anomaly detection in video surveillance using continual learning.
problem Challenges in continual learning for high-dimensional applications like video surveillance.
method Transfer learning and continual learning for online anomaly detection.
result Significantly reduces training complexity and continual learning from recent data.
Improved bio-surveillance through automated document classification.
problem Tracking infectious diseases across global news alerts.
method Recurrent neural networks, TF-IDF, Naive Bayes, logistic regression.
result 97% recall and 93.3% accuracy in bio-surveillance event classification.
Classifiers and beamforming algorithms improved audio surveillance detection accuracy.
problem Detecting surveillance sound events with high accuracy and efficiency.
method Evaluated seven classifiers and two beamforming algorithms; used data augmentation and tested with varying SNR levels.
result SVM and Delay-and-Sum (DaS) combination achieved the highest accuracy (86.0%), but had high computational cost.
New algorithm rSVDdpd improves robustness and scalability for video surveillance background modeling.
problem Camera tampering and noisy videos make background separation challenging.
method Introduces rSVDdpd, a robust singular value decomposition technique for scalable video surveillance.
result Demonstrates superior performance on benchmark and real-life datasets.
This paper explores using a Long short-term memory (LSTM) based sequence autoencoder to learn interesting features for detecting surveillance aircraft using ADS-B flight data. An aircraft periodically broadcasts ADS-B (Automatic Dependent Surveillance - Broadcast) data to ground receivers. The ability of LSTM networks …
Online anomaly detection in surveillance videos with false alarm rate bounds.
problem Lack of theoretical performance analysis and online decision making in anomaly detection.
method Proposes an online anomaly detection method with asymptotic bounds on false alarm rate.
result Demonstrates effectiveness on publicly available data sets, outperforming state-of-the-art algorithms.
Smart city surveillance benefits from sound event recognition.
problem Improving monitoring capabilities in smart cities.
method Exploration of several classifiers on the SESA dataset.
result SGD achieved 72.13% accuracy in sound event recognition.
Online surveillance detects systemic risk in financial markets.
problem Detecting and monitoring systemic risk in financial markets.
method Online monitoring procedures for multiple series, controlling for false rejections.
result Procedures allow timely detection of financial distress.
Supervised learning improves disease outbreak detection accuracy.
problem Early detection of infectious disease outbreaks to protect public health.
method Developed a supervised learning approach based on hidden Markov models for disease outbreak detection.
result Reduces false positive rate by up to 50% while maintaining sensitivity.
Paper describes a video surveillance system for highway traffic events.
problem Detecting specific sequences of situations in highway traffic videos.
method Compares RNN and CNN architectures for analyzing video frames and sequences.
result Best architecture performs well in real conditions.
Model predicts anti-cancer drug responses using gene and molecular data.
problem Expensive and time-consuming cancer drug discovery and tailoring.
method Uses variational autoencoders and multi-layer perceptrons to encode gene expression and drug data.
result High average R2 of 0.83 and 0.845 in predicting drug responses for breast and pan-cancer cell lines, respectively. Study uses machine learning to predict heart failure in cancer patients.
problem Early detection of cancer patients at risk for cardiotoxicity.
method Examined four machine learning algorithms on 143,199 cancer patients.
result Gradient boosting model achieved best AUC score of 0.9077.
Maximising the detection of intrusions is a fundamental and often critical aim of perimeter surveillance. Commonly, this requires a decision-maker to optimally allocate multiple searchers to segments of the perimeter. We consider a scenario where the decision-maker may sequentially update the searchers' allocation, lea…
System accurately detects lung cancer from CT images.
problem Early and accurate detection of lung cancer.
method Developed algorithms using a dataset of CT images.
result Accuracy of 72.2% on test dataset.
We estimate treatment cost-savings from early cancer diagnosis. For breast, lung, prostate and colorectal cancers and melanoma, which account for more than 50% of new incidences projected in 2017, we combine published cancer treatment cost estimates by stage with incidence rates by stage at diagnosis. We extrapolate to…
We present a novel method for extracting cancer signatures by applying statistical risk models (http://ssrn.com/abstract=2732453) from quantitative finance to cancer genome data. Using 1389 whole genome sequenced samples from 14 cancers, we identify an "overall" mode of somatic mutational noise. We give a prescription …
Study predicts 10-year survival rates for breast cancer patients.
problem Predicting long-term survival of breast cancer patients.
method Machine learning approaches to assess survival rates.
result Improved accuracy in predicting 10-year survival.
Predicting epidemic dynamics is of great value in understanding and controlling diffusion processes, such as infectious disease spread and information propagation. This task is intractable, especially when surveillance resources are very limited. To address the challenge, we study the problem of active surveillance, i.…
Paper identifies key CpG methylation sites for breast cancer.
problem Early detection and treatment of breast cancer.
method Used machine learning on TCGA dataset to classify cancer vs. non-cancer samples.
result Reduced model with 25 key CpG sites achieves over 94% accuracy.
Data mining techniques predict breast cancer types with high accuracy.
problem Early detection of breast cancer to reduce mortality rates.
method Twelve classification algorithms applied to the Breast Cancer Wisconsin dataset.
result High accuracy in predicting malignant and benign breast cancer.
With the increased affordability and availability of whole-genome sequencing, large-scale and high-throughput gene expression is widely used to characterize diseases, including cancers. However, establishing specificity in cancer diagnosis using gene expression data continues to pose challenges due to the high dimensio…
Study examines perceptions and attitudes about breast cancer on Twitter.
problem Understanding public perceptions and attitudes towards breast cancer on social media.
method Identified and collected tweets, used topic modeling and sentiment analysis.
result Identified themes and quantified users' perceptions and emotions about breast cancer.
Deep learning predicts breast cancer with high accuracy from patient data.
problem Early detection of breast cancer from patient data.
method Feature selection and k-fold Monte Carlo cross-validation using deep learning.
result Deep learning model effectively distinguishes between cancer and healthy patients.
Machine learning accurately diagnoses cancer from whole genome sequencing data.
problem Accurate cancer diagnosis at all stages.
method Novel MLAC (Machine Learning Against Cancer) method using next-gen RNA sequencing.
result Perfect precision, sensitivity, and specificity achieved for most tumor types.
Neural networks improve cancer risk prediction from family history data.
problem Improving cancer risk prediction from family history data using machine learning.
method Developed and trained neural network models on large pedigrees to predict hereditary cancers.
result Neural networks can achieve nearly optimal prediction performance and outperform traditional models in misreported data.
Over the past decades, both critical care and cancer care have improved substantially. Due to increased cancer-specific survival, we hypothesized that both the number of cancer patients admitted to the ICU and overall survival have increased since the millennium change. MIMIC-III, a freely accessible critical care data…
Lung cancer continues to be a major healthcare challenge with high morbidity and mortality rates among both men and women worldwide. The majority of lung cancer cases are of non-small cell lung cancer type. With the advent of targeted cancer therapy, it is imperative not only to properly diagnose but also sub-classify …
We present *K-means clustering algorithm and source code by expanding statistical clustering methods applied in https://ssrn.com/abstract=2802753 to quantitative finance. *K-means is statistically deterministic without specifying initial centers, etc. We apply *K-means to extracting cancer signatures from genome data w…
Accurately predicting drug responses to cancer is an important problem hindering oncologists' efforts to find the most effective drugs to treat cancer, which is a core goal in precision medicine. The scientific community has focused on improving this prediction based on genomic, epigenomic, and proteomic datasets measu…
System automates identification of cancer drug repurposing from PubMed.
problem Manual extraction of cancer drug repurposing evidence from scientific publications is infeasible.
method NLP pipeline including querying, filtering, entity extraction, classification, and study type classification.
result Automated system extracts cancer drug repurposing evidence from PubMed abstracts.
Study identifies biomarkers for lung cancer in female non-smokers.
problem Identifying prognostic biomarkers for stage III NSCLC in non-smoking females.
method Gene expression profiling and XGBoost machine learning algorithm.
result Top biomarkers validated in literature, with AUC score of 0.835.
PathologyGAN learns deep representations of cancer tissue images.
problem Limited high-quality labels for cancer tissue images.
method Developed a GAN framework for unsupervised learning of cancer tissue phenotypes.
result Generated high-quality images with interpretable latent space.
Deep CNN model improves breast cancer screening exam classification.
problem Improving accuracy in breast cancer screening exam classification.
method Localization-based deep CNN trained on 200,000 exams.
result AUC of 0.919 in predicting malignancy, reducing error rate by 23%.
We apply our statistically deterministic machine learning/clustering algorithm *K-means (recently developed in https://ssrn.com/abstract=2908286) to 10,656 published exome samples for 32 cancer types. A majority of cancer types exhibit mutation clustering structure. Our results are in-sample stable. They are also out-o…
Modeling correlated mutations in cancer for personalized treatment.
problem Identifying mutations for personalized cancer therapy in heterogeneous profiles.
method Proposed correlated zero-inflated negative binomial process with mixed beta-Bernoulli and variational inference.
result Identified biologically relevant correlations between somatic mutations.
Network Elastic Net identifies smoking-specific gene expression for lung cancer prognosis.
problem Identifying smoking-specific gene expression biomarkers in lung cancer prognosis.
method Introduces Network Elastic Net, a method that clusters and regresses on graphs based on smoking behavior.
result Shows efficacy of clusters in identifying cancer stages using gene expression and smoking behavior.
Automates deep learning model development for cancer data.
problem Manual design of high-performing deep learning models for cancer data is time-consuming and requires expertise.
method Reinforcement-learning-based neural architecture search with custom building blocks.
result Automated discovery of deep neural network architectures with similar or higher accuracy.
Anomaly detection identifies unusual malaria transmission patterns in Ghana.
problem Identifying atypical malaria transmission patterns in Ghana's spatiotemporal surveillance data.
method Consensus-based anomaly detection framework applied to monthly malaria surveillance data.
result High-burden areas are not necessarily those with the most frequent anomalous transmission.
BIDIFAC+ factorizes linked matrices for cancer studies.
problem Integrating multiple omics platforms across various cancer types.
method Flexible approach to simultaneous factorization and decomposition of linked matrices using BIDIFAC+.
result Identifies shared and specific modes of variability across multiple omics platforms and cancer types.
Paper proposes scalable method for analyzing multi-omic data.
problem Integrating high-dimensional multi-omic data for cancer subtyping.
method Mixed graphical model approach using Birth-Death MCMC algorithm.
result Our method outperforms LASSO and standard BDMCMC in computational efficiency and model selection accuracy.
Model learns cancer tissue images onto a low-dimensional space revealing tissue characteristics.
problem Improving cancer diagnosis through high-fidelity digital pathology.
method Deep generative model using PathologyGAN to map real images onto a latent space.
result Latent space encodes morphological characteristics and reveals distinct tissue clusters.
Machine learning can predict cancer with 100% accuracy on a dataset.
problem Accuracy of cancer predictions using machine learning.
method Extensive experiments on the Wisconsin Diagnostic Breast Cancer dataset.
result Machine learning algorithms can be easily misled to achieve 100% accuracy.
Breast cancer is the most frequently reported cancer type among the women around the globe and beyond that it has the second highest female fatality rate among all cancer types. Despite all the progresses made in prevention and early intervention, early prognosis and survival prediction rates are still unsatisfactory. …
Transfer learning from breast histopathology improves prostate cancer detection.
problem Insufficient prostate histopathology datasets for training.
method Transfer learning from breast histopathology images.
result Proposed approach outperforms transfer learning from ImageNet dataset.
Study identifies cancer genes through graph anomaly analysis of protein interactions.
problem Insufficient modeling of biological information in protein interaction networks for cancer gene identification.
method Proposes HIerarchical-Perspective Graph Neural Network (HIPGNN) to detect weight heterogeneity and spectral flattening in cancer gene nodes.
result HIPGNN detects weight heterogeneity and spectral flattening, leading to improved cancer gene identification.