Paper identifies key CpG methylation sites for breast cancer.
arXiv research
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Paper presents a machine learning method to predict cancer sub-clones.
Paper proposes scalable method for analyzing multi-omic data.
Understanding the phenotypic drug response on cancer cell lines plays a vital rule in anti-cancer drug discovery and re-purposing. The Genomics of Drug Sensitivity in Cancer (GDSC) database provides open data for researchers in phenotypic screening to test their models and methods. Previously, most research in these ar…
Paper tackles cancer mutation data challenges by creating useful low-dimensional representations.
Cancer analysis and prediction is the utmost important research field for well-being of humankind. The Cancer data are analyzed and predicted using machine learning algorithms. Most of the researcher claims the accuracy of the predicted results within 99%. However, we show that machine learning algorithms can easily pr…
Repository tackles fake health news in cancer research.
Among American women, the rate of breast cancer is only second to lung cancer. An estimated 12.4% women will develop breast cancer over the course of their lifetime. The widespread use of social media across the socio-economic spectrum offers unparalleled ways to facilitate information sharing, in particular as it pert…
Study compares single vs ensemble feature selection for cancer diagnosis.
Study identifies biomarkers for lung cancer in female non-smokers.
Cancer is a complex disease, the understanding and treatment of which are being aided through increases in the volume of collected data and in the scale of deployed computing power. Consequently, there is a growing need for the development of data-driven and, in particular, deep learning methods for various tasks such …
Improving cancer treatment decisions requires considering causal effects, not just model accuracy.
There are various algorithms and methodologies used for automated screening of cervical cancer by segmenting and classifying cervical cancer cells into different categories. This study presents a critical review of different research papers published that integrated AI methods in screening cervical cancer via different…
Despite great advances, molecular cancer pathology is often limited to the use of a small number of biomarkers rather than the whole transcriptome, partly due to computational challenges. Here, we introduce a novel architecture of Deep Neural Networks (DNNs) that is capable of simultaneous inference of various properti…
Objectives: Most cancer data sources lack information on metastatic recurrence. Electronic medical records (EMRs) and population-based cancer registries contain complementary information on cancer treatment and outcomes, yet are rarely used synergistically. To enable detection of metastatic breast cancer (MBC), we appl…
Late diagnosis and high costs are key factors that negatively impact the care of cancer patients worldwide. Although the availability of biological markers for the diagnosis of cancer type is increasing, costs and reliability of tests currently present a barrier to the adoption of their routine use. There is a pressing…
Deep learning model explains breast cancer subtypes using logistic regression.
An algorithm reduces breast cancer detection data complexity using effect sizes.
This study predicts ovarian cancer from cysts using TVUS and machine learning.
Cancer survival prediction is an active area of research that can help prevent unnecessary therapies and improve patient's quality of life. Gene expression profiling is being widely used in cancer studies to discover informative biomarkers that aid predict different clinical endpoint prediction. We use multiple modalit…
MINN-SA enhances cancer detection using TCR sequences with better interpretability.
The medical research facilitates to acquire a diverse type of data from the same individual for particular cancer. Recent studies show that utilizing such diverse data results in more accurate predictions. The major challenge faced is how to utilize such diverse data sets in an effective way. In this paper, we introduc…
Deep learning, through the use of neural networks, has demonstrated remarkable ability to automate many routine tasks when presented with sufficient data for training. The neural network architecture (e.g. number of layers, types of layers, connections between layers, etc.) plays a critical role in determining what, if…
Sparse Canonical Correlation Analysis (CCA) has received considerable attention in high-dimensional data analysis to study the relationship between two sets of random variables. However, there has been remarkably little theoretical statistical foundation on sparse CCA in high-dimensional settings despite active methodo…
AI framework uses multi-omics data to personalize cancer treatment suggestions.
Proposes a multi-resolution model for prostate cancer classification using mpMRI.
Method uses network biology to construct gene expression models for cancer.
TransST improves spatial transcriptomics data analysis by identifying cell clusters and biomarkers.
The potential benefits of applying machine learning methods to -omics data are becoming increasingly apparent, especially in clinical settings. However, the unique characteristics of these data are not always well suited to machine learning techniques. These data are often generated across different technologies in dif…
Data integration methods that analyze multiple sources of data simultaneously can often provide more holistic insights than can separate inquiries of each data source. Motivated by the advantages of data integration in the era of "big data", we investigate feature selection for high-dimensional multi-view data with mix…
Many researches demonstrated that the DNA methylation, which occurs in the context of a CpG, has strong correlation with diseases, including cancer. There is a strong interest in analyzing the DNA methylation data to find how to distinguish different subtypes of the tumor. However, the conventional statistical methods …
A rigorous ML pipeline for binary classification in biomedical studies, focusing on pancreatic cancer.
New framework distinguishes lung cancer subtypes using MALDI mass spectrometry.
Model predicts anti-cancer drug responses using gene and molecular data.
PKB framework boosts genomic data analysis by integrating pathway knowledge.
System accurately detects lung cancer from CT images.
In this paper we describe a novel implementation of adaboost for prediction of survival function. We take different variations of the algorithm and compare the algorithms based on system run time and root mean square error. Our construction includes right censoring data and competing risk data too. We take different da…
We estimate treatment cost-savings from early cancer diagnosis. For breast, lung, prostate and colorectal cancers and melanoma, which account for more than 50% of new incidences projected in 2017, we combine published cancer treatment cost estimates by stage with incidence rates by stage at diagnosis. We extrapolate to…
We present a novel method for extracting cancer signatures by applying statistical risk models (http://ssrn.com/abstract=2732453) from quantitative finance to cancer genome data. Using 1389 whole genome sequenced samples from 14 cancers, we identify an "overall" mode of somatic mutational noise. We give a prescription …
Study predicts 10-year survival rates for breast cancer patients.
Cardiotoxicity related to cancer therapies has become a serious issue, diminishing cancer treatment outcomes and quality of life. Early detection of cancer patients at risk for cardiotoxicity before cardiotoxic treatments and providing preventive measures are potential solutions to improve cancer patients's quality of …
With the increased affordability and availability of whole-genome sequencing, large-scale and high-throughput gene expression is widely used to characterize diseases, including cancers. However, establishing specificity in cancer diagnosis using gene expression data continues to pose challenges due to the high dimensio…
Deep learning predicts breast cancer with high accuracy from patient data.
Machine learning accurately diagnoses cancer from whole genome sequencing data.
Neural networks improve cancer risk prediction from family history data.
Over the past decades, both critical care and cancer care have improved substantially. Due to increased cancer-specific survival, we hypothesized that both the number of cancer patients admitted to the ICU and overall survival have increased since the millennium change. MIMIC-III, a freely accessible critical care data…
Bayesian Cox model identifies biomarkers from multi-omics data.
Two new feature selection methods improve breast cancer diagnosis accuracy.