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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

169,181 papers · 148 categories

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481216 · Sep 201919922001200920182026
48 results for cancer onset

Study uses ML to predict cancer patient mortality from FN onset.

problem Predicting mortality in cancer patients with FN to improve survival.
method Multi-domain machine learning models using HCUP data.
result Clinical diagnoses have highest predictive power for FN mortality.

SurvLatent ODE predicts VTE risk for cancer patients, outperforming current methods.

problem Predicting clinical outcomes from irregularly sampled EHR data with competing events.
method Neural ODE-based Recurrent Neural Networks (ODE-RNN) for flexible survival time estimation.
result SurvLatent ODE outperforms Khorana Risk scores for VTE risk prediction.

DDP models dynamic comorbidity networks from event data.

problem Understanding complex temporal patterns of co-occurring diseases.
method Developed deep diffusion processes (DDP) to model dynamic comorbidity networks.
result DDP enables accurate risk prediction and interpretable disease trajectories.

New method synthesizes piano training data, improving transcription performance.

problem Lack of large piano datasets limits note onset transcription models.
method Synthesizes arbitrary training data, models piano dynamics, avoids disentanglement problem.
result Achieves good transcription performance on MAPS dataset and excellent generalization.

Estimates cost savings from early cancer diagnosis.

problem Improving early cancer diagnosis to reduce treatment costs.
method Combining published cancer treatment cost estimates by stage with incidence rates by stage at diagnosis, and extrapolating to other cancer sites.
result Estimates U.S. national annual treatment cost-savings from early cancer diagnosis in the trillions.

Model predicts anti-cancer drug responses using gene and molecular data.

problem Expensive and time-consuming cancer drug discovery and tailoring.
method Uses variational autoencoders and multi-layer perceptrons to encode gene expression and drug data.
result High average R2R^{2} of 0.83 and 0.845 in predicting drug responses for breast and pan-cancer cell lines, respectively.

Deep learning models improve cancer detection and typing classification from gene expression data.

problem Challenges in establishing specificity for cancer diagnosis using gene expression data.
method Developed deep learning models using mRNA datasets for cancer detection and typing classification.
result Achieved 98% accuracy in cancer detection and 18 out of 32 cancer-typing classifications over 90% accuracy.

We present a novel method for extracting cancer signatures by applying statistical risk models (http://ssrn.com/abstract=2732453) from quantitative finance to cancer genome data. Using 1389 whole genome sequenced samples from 14 cancers, we identify an "overall" mode of somatic mutational noise. We give a prescription …

2016-04-29abs ↗pdf ↗

Cancer patients admitted to ICU had improved survival over 10 years.

problem To assess changes in survival of cancer patients admitted to ICU over 10 years.
method Retrospective analysis of MIMIC-III database, adjusted for confounders using logistic regression.
result Cancer patients had significantly lower 28-day and 1-year mortality rates over 10 years.

Data mining techniques predict breast cancer types with high accuracy.

problem Early detection of breast cancer to reduce mortality rates.
method Twelve classification algorithms applied to the Breast Cancer Wisconsin dataset.
result High accuracy in predicting malignant and benign breast cancer.

Study examines perceptions and attitudes about breast cancer on Twitter.

problem Understanding public perceptions and attitudes towards breast cancer on social media.
method Identified and collected tweets, used topic modeling and sentiment analysis.
result Identified themes and quantified users' perceptions and emotions about breast cancer.

Machine learning clusters mutations in cancer exomes, improving diagnostic speed and cost.

problem Extracting stable mutation structures from cancer exome data for early diagnostics.
method Statistically deterministic machine learning algorithm *K-means applied to exome samples.
result Majority of cancer types exhibit stable mutation clustering, while NMF methods are unstable.

Machine learning accurately diagnoses cancer from whole genome sequencing data.

problem Accurate cancer diagnosis at all stages.
method Novel MLAC (Machine Learning Against Cancer) method using next-gen RNA sequencing.
result Perfect precision, sensitivity, and specificity achieved for most tumor types.

Neural networks improve cancer risk prediction from family history data.

problem Improving cancer risk prediction from family history data using machine learning.
method Developed and trained neural network models on large pedigrees to predict hereditary cancers.
result Neural networks can achieve nearly optimal prediction performance and outperform traditional models in misreported data.

Machine learning detects metastatic breast cancer cases from linked EMR and cancer registry data.

problem Lack of metastatic recurrence data in cancer registries and EMRs.
method Semi-supervised machine learning on linked EMR and CCR data.
result Model achieved high accuracy in detecting metastatic breast cancer cases.

L-Perceptron improves breast cancer diagnosis and survival prediction.

problem Improving early prognosis and survival prediction rates for breast cancer.
method Proposes a novel type of perceptron (L-Perceptron) for better accuracy and sensitivity.
result Achieves 97.42% and 98.73% accuracy and sensitivity in Wisconsin Breast Cancer dataset.

We present *K-means clustering algorithm and source code by expanding statistical clustering methods applied in https://ssrn.com/abstract=2802753 to quantitative finance. *K-means is statistically deterministic without specifying initial centers, etc. We apply *K-means to extracting cancer signatures from genome data w…

2017-03-02abs ↗pdf ↗

Accurately predicting drug responses to cancer is an important problem hindering oncologists' efforts to find the most effective drugs to treat cancer, which is a core goal in precision medicine. The scientific community has focused on improving this prediction based on genomic, epigenomic, and proteomic datasets measu…

2016-12-02abs ↗pdf ↗

Method identifies financial rogue waves close to their onset.

problem Identifying extreme financial events close to their onset.
method Analogy between rogue waves in optics and financial volatility, using Schrödinger equation with potential shaped by Kerr nonlinearity.
result Numerical gradient spikes at the onset of extreme financial events.

System automates identification of cancer drug repurposing from PubMed.

problem Manual extraction of cancer drug repurposing evidence from scientific publications is infeasible.
method NLP pipeline including querying, filtering, entity extraction, classification, and study type classification.
result Automated system extracts cancer drug repurposing evidence from PubMed abstracts.

GMMSEQ clusters AE data streams, identifying cluster onsets and growth.

problem Clustering unlabeled AE data with onsets and growth information.
method Modified Gaussian Mixture Models (GMM) with an objective function for AE timestamps.
result GMMSEQ provides better cluster characterization than standard methods.

Study identifies biomarkers for lung cancer in female non-smokers.

problem Identifying prognostic biomarkers for stage III NSCLC in non-smoking females.
method Gene expression profiling and XGBoost machine learning algorithm.
result Top biomarkers validated in literature, with AUC score of 0.835.

Modeling correlated mutations in cancer for personalized treatment.

problem Identifying mutations for personalized cancer therapy in heterogeneous profiles.
method Proposed correlated zero-inflated negative binomial process with mixed beta-Bernoulli and variational inference.
result Identified biologically relevant correlations between somatic mutations.

Network Elastic Net identifies smoking-specific gene expression for lung cancer prognosis.

problem Identifying smoking-specific gene expression biomarkers in lung cancer prognosis.
method Introduces Network Elastic Net, a method that clusters and regresses on graphs based on smoking behavior.
result Shows efficacy of clusters in identifying cancer stages using gene expression and smoking behavior.

The study improves colorectal cancer survivability prediction by considering ethnicity.

problem Improving colorectal cancer survivability prediction using machine learning.
method Machine learning techniques applied to SEER cancer incidence database, comparing different ethnicities.
result Models perform better on single-ethnicity populations and provide different feature importance rankings.

Automates deep learning model development for cancer data.

problem Manual design of high-performing deep learning models for cancer data is time-consuming and requires expertise.
method Reinforcement-learning-based neural architecture search with custom building blocks.
result Automated discovery of deep neural network architectures with similar or higher accuracy.

BIDIFAC+ factorizes linked matrices for cancer studies.

problem Integrating multiple omics platforms across various cancer types.
method Flexible approach to simultaneous factorization and decomposition of linked matrices using BIDIFAC+.
result Identifies shared and specific modes of variability across multiple omics platforms and cancer types.

Paper proposes scalable method for analyzing multi-omic data.

problem Integrating high-dimensional multi-omic data for cancer subtyping.
method Mixed graphical model approach using Birth-Death MCMC algorithm.
result Our method outperforms LASSO and standard BDMCMC in computational efficiency and model selection accuracy.

Model learns cancer tissue images onto a low-dimensional space revealing tissue characteristics.

problem Improving cancer diagnosis through high-fidelity digital pathology.
method Deep generative model using PathologyGAN to map real images onto a latent space.
result Latent space encodes morphological characteristics and reveals distinct tissue clusters.

Model predicts drug response in tumors using genomic profiles.

problem Challenges in translating genomic insights to tumor-specific drug response predictions.
method Deep neural network (DNN) model trained on mutation and expression profiles of cancer cell lines.
result Achieved mean squared error of 1.96 for predicting IC50 values of 265 drugs.