Brain networks have received considerable attention given the critical significance for understanding human brain organization, for investigating neurological disorders and for clinical diagnostic applications. Structural brain network (e.g. DTI) and functional brain network (e.g. fMRI) are the primary networks of inte…
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48 results for “brain-network”
New method predicts AD progression using MEG brain networks.
problem Early diagnosis and prediction of Alzheimer's disease progression.
method MG2G, a deep learning method that maps brain networks into a latent space.
result MG2G detects subtle brain connectivity patterns and predicts AD progression.
In this paper, we consider the problem of estimating multiple graphical models simultaneously using the fused lasso penalty, which encourages adjacent graphs to share similar structures. A motivating example is the analysis of brain networks of Alzheimer's disease using neuroimaging data. Specifically, we may wish to e…
In many human brain network studies, we do not have sufficient number (n) of images relative to the number (p) of voxels due to the prohibitively expensive cost of scanning enough subjects. Thus, brain network models usually suffer the small-n large-p problem. Such a problem is often remedied by sparse network models, …
A new geometric framework embeds correlation matrices into Euclidean space for scalable brain network analysis.
problem Inefficient and unstable analysis of functional brain networks in high-dimensional contexts.
method Diffeomorphic transformations to embed correlation matrices into Euclidean space, preserving manifold properties.
result Improved computational speed and enhanced accuracy compared to conventional manifold-based approaches.
Network analysis of human brain connectivity is critically important for understanding brain function and disease states. Embedding a brain network as a whole graph instance into a meaningful low-dimensional representation can be used to investigate disease mechanisms and inform therapeutic interventions. Moreover, by …
SM-netFusion estimates brain network atlas by considering multiple topological measures.
problem Limited BNA estimation methods that overlook topological measures and lack discriminative power.
method Supervised multi-topology network cross-diffusion framework using degree, closeness, and eigenvector centrality measures.
result SM-netFusion produces more centered and representative templates, and improves classification accuracy.
Schizophrenia, a mental disorder that is characterized by abnormal social behavior and failure to distinguish one's own thoughts and ideas from reality, has been associated with structural abnormalities in the architecture of functional brain networks. Using various methods from network analysis, we examine the effect …
Brain networks in fMRI are typically identified using spatial independent component analysis (ICA), yet mathematical constraints such as sparse coding and positivity both provide alternate biologically-plausible frameworks for generating brain networks. Non-negative Matrix Factorization (NMF) would suppress negative BO…
LOCUS separates brain network connectivity matrices efficiently.
problem High dimensionality, latent sources, and spurious findings in analyzing brain connectivity matrices.
method LOCUS: low-rank structure with uniform sparsity, iterative Node-Rotation algorithm.
result LOCUS achieves more efficient and accurate source separation for connectivity matrices.
A new mathematical approach detects frequency-based alterations in brain networks.
problem Understanding disease-relevant brain alterations through network analysis.
method Proposes a novel connectome harmonic analysis framework using common harmonic waves learned from Stiefel manifolds.
result Identifies more significant and reproducible network dysfunction patterns in Alzheimer's disease.
STCA discovers dynamic functional brain networks using spatial-temporal convolution and attention.
problem Lack of dynamic exploration of functional brain networks.
method Spatial-Temporal Convolutional Attention (STCA) model.
result STCA can discover dynamic functional brain networks in a novel way.
Unified framework detects dynamic community structure in brain networks across individuals.
problem Detecting community structure in functional brain networks across multiple subjects and over time.
method Markov-switching stochastic block model (MSS-SBM) for multilayer brain networks.
result Captures dynamic reconfiguration of modular connectivity in brain networks across different task conditions.
This paper advocates Riemannian multi-manifold modeling in the context of network-wide non-stationary time-series analysis. Time-series data, collected sequentially over time and across a network, yield features which are viewed as points in or close to a union of multiple submanifolds of a Riemannian manifold, and dis…
This paper clusters networks with annotated time-series data using kernel-ARMA and Grassmannian geometry.
problem Clustering networks with annotated time-series data, including state, node, and subnetwork clustering.
method Extract features from time-series data using kernel-ARMA, map onto Grassmannian, and cluster using Riemannian geometry.
result The proposed framework outperforms state-of-the-art clustering schemes on brain-network data.
Recent advances in neuroscience and in the technology of functional magnetic resonance imaging (fMRI) and electro-encephalography (EEG) have propelled a growing interest in brain-network clustering via time-series analysis. Notwithstanding, most of the brain-network clustering methods revolve around state clustering an…
Autoencoders identify brain networks linked to stress and genotype.
problem Designing effective brain stimulation protocols for mental illnesses.
method Supervised autoencoders to model multi-region brain activity.
result Autoencoders reveal a stress-related brain network associated with a bipolar disorder genotype.
Simultaneous prediction and community detection for networks with application to neuroimagingstat.ME
Method predicts brain regions for neuroimaging phenotypes.
problem Predicting phenotypes from brain networks without static community structure.
method Supervised community detection using block-structured regularization and ADMM optimization.
result The method identifies task-specific brain regions that improve phenotype prediction.
The main goal of this study is to extract a set of brain networks in multiple time-resolutions to analyze the connectivity patterns among the anatomic regions for a given cognitive task. We suggest a deep architecture which learns the natural groupings of the connectivity patterns of human brain in multiple time-resolu…
Learning a similarity metric has gained much attention recently, where the goal is to learn a function that maps input patterns to a target space while preserving the semantic distance in the input space. While most related work focused on images, we focus instead on learning a similarity metric for neuroimages, such a…
Mining discriminative subgraph patterns from graph data has attracted great interest in recent years. It has a wide variety of applications in disease diagnosis, neuroimaging, etc. Most research on subgraph mining focuses on the graph representation alone. However, in many real-world applications, the side information …
Graph learning method improves brain state classification.
problem Classifying brain states from iEEG signals.
method Representation learning on graphs for time-varying brain networks.
result 9.13% improvement in AUC for seizure vs. non-seizure classification.
Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human functional brain networks, the network structure is often inferred from functional m…
Stochastic encoding improves gender classification of brain networks from UK Biobank data.
problem Complexity and bias in interpreting deep learning models of brain connectivity.
method Stochastic encoding in ensemble of CNNs, multivariate balancing algorithm.
result AUROC of 0.8459, with resting-state data more accurate than task data.
In clinical and neuroscientific studies, systematic differences between two populations of brain networks are investigated in order to characterize mental diseases or processes. Those networks are usually represented as graphs built from neuroimaging data and studied by means of graph analysis methods. The typical mach…
A new method clusters complex networks using topological and geometric structure.
problem Clustering complex networks with intricate topology.
method Centroid-based clustering strategy using Wasserstein distance and barycenter for persistence barcodes.
result Demonstrated effectiveness on simulated and real-world networks.
Functional brain networks exhibit dynamics on the sub-second temporal scale and are often assumed to embody the physiological substrate of cognitive processes. Here we analyse the temporal and spatial dynamics of these states, as measured by EEG, with a hidden Markov model and compare this approach to classical EEG mic…
A Hierarchical Graphical Model for Big Inverse Covariance Estimation with an Application to fMRIstat.ME
Brain networks has attracted the interests of many neuroscientists. From functional MRI (fMRI) data, statistical tools have been developed to recover brain networks. However, the dimensionality of whole-brain fMRI, usually in hundreds of thousands, challenges the applicability of these methods. We develop a hierarchica…
CI-GNN uses GNNs to diagnose psychiatric disorders by identifying causally relevant brain regions.
problem Leveraging GNNs for psychiatric diagnosis requires interpretable models to understand decision-making.
method CI-GNN integrates Granger causality into GNNs to identify causally relevant subgraphs.
result CI-GNN provides more reliable and concise explanations of psychiatric diagnoses.
We propose a novel framework for graph mean computation.
problem Defining a mean for graph data is difficult.
method Embeddings in the space of smooth graph signal distributions, using the Wasserstein metric.
result Existence and uniqueness of the graph mean established, and an iterative algorithm provided.
The functional and structural representation of the brain as a complex network is marked by the fact that the comparison of noisy and intrinsically correlated high-dimensional structures between experimental conditions or groups shuns typical mass univariate methods. Furthermore most network estimation methods cannot d…
Current high-throughput data acquisition technologies probe dynamical systems with different imaging modalities, generating massive data sets at different spatial and temporal resolutions posing challenging problems in multimodal data fusion. A case in point is the attempt to parse out the brain structures and networks…
GNNs improve brain activity forecasting in fMRI studies.
problem Understanding neural dynamics in the brain.
method Comparison of GNN architectures for modeling fMRI data.
result GNNs outperform VAR models in robustly scaling to large network studies.
Unified model learns joint and individual features from brain imaging data.
problem Integrating structural and functional connectivity data for behavioral phenotypes.
method Cross-Modal Joint-Individual Variational Network (CM-JIVNet) with multi-head attention fusion.
result CM-JIVNet outperforms in cross-modal reconstruction and behavioral trait prediction.
A new kernel measures brain network similarities, improving disease classification.
problem Lack of edge weight information in existing graph kernels for brain connectivity networks.
method Ordinal pattern kernel for weighted brain connectivity networks.
result The ordinal pattern kernel achieves better classification performance than state-of-the-art graph kernels.
Paper introduces a framework for diagnosing Alzheimer's disease using higher-order topological features from fMRI.
problem Diagnosing Alzheimer's disease using brain network topology.
method Persistent homology to extract higher-order features (cycles, cavities) from fMRI data.
result Framework significantly outperforms existing methods in AD classification.
This paper considers the problem of brain disease classification based on connectome data. A connectome is a network representation of a human brain. The typical connectome classification problem is very challenging because of the small sample size and high dimensionality of the data. We propose to use simultaneous app…
Machine learning for ASD diagnosis using morphological MRI networks.
problem Challenging to diagnose ASD using MRI due to heterogeneity and incomplete network neuroscience.
method Crowdsourced Kaggle competition to develop and benchmark ML pipelines.
result First-ranked team achieved 70% accuracy, 72.5% sensitivity, and 67.5% specificity.
Resting-state functional MRI (rs-fMRI) in functional neuroimaging techniques have improved in brain disorders, dysfunction studies via mapping the topology of the brain connections, i.e. connectopic mapping. Since, there are the slight differences between healthy and unhealthy brain regions and functions, investigation…
Measuring dependence between two random variables is very important, and critical in many applied areas such as variable selection, brain network analysis. However, we do not know what kind of functional relationship is between two covariates, which requires the dependence measure to be equitable. That is, it gives sim…
A new method clusters subjects based on brain networks without vectorizing fMRI data.
problem Distortion of clustering results when simplifying fMRI data structure.
method Wishart mixture models for multiple-view clustering of brain networks.
result Identifies multiple underlying pairs of associations between subject clusters and brain sub-networks.
New method identifies causal brain connections from fMRI data.
problem Identifying causal brain interactions from statistical associations.
method ψ-learning incorporated linear non-Gaussian acyclic model (-LiNGAM).
result Identified three types of hub structures and 16 causal flows.
Numerous social, medical, engineering and biological challenges can be framed as graph-based learning tasks. Here, we propose a new feature based approach to network classification. We show how dynamics on a network can be useful to reveal patterns about the organization of the components of the underlying graph where …
In this era of data deluge, many signal processing and machine learning tasks are faced with high-dimensional datasets, including images, videos, as well as time series generated from social, commercial and brain network interactions. Their efficient processing calls for dimensionality reduction techniques capable of p…
We present an approach to model time series data from resting state fMRI for autism spectrum disorder (ASD) severity classification. We propose to adopt kernel machines and employ graph kernels that define a kernel dot product between two graphs. This enables us to take advantage of spatio-temporal information to captu…
We propose a new family of combinatorial inference problems for graphical models. Unlike classical statistical inference where the main interest is point estimation or parameter testing, combinatorial inference aims at testing the global structure of the underlying graph. Examples include testing the graph connectivity…
Deep Neural Networks (DNNs) are usually over-parameterized, causing excessive memory and interconnection cost on the hardware platform. Existing pruning approaches remove secondary parameters at the end of training to reduce the model size; but without exploiting the intrinsic network property, they still require the f…
Joint Learning of Graph Representation and Node Features in Graph Convolutional Neural Networkscs.LG
Graph Convolutional Neural Networks (GCNNs) extend classical CNNs to graph data domain, such as brain networks, social networks and 3D point clouds. It is critical to identify an appropriate graph for the subsequent graph convolution. Existing methods manually construct or learn one fixed graph for all the layers of a …