Fine-grained atlases improve fMRI analysis of brain activity.
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Probabilistic atlases provide essential spatial contextual information for image interpretation, Bayesian modeling, and algorithmic processing. Such atlases are typically constructed by grouping subjects with similar demographic information. Importantly, use of the same scanner minimizes inter-group variability. Howeve…
We present two related methods for deriving connectivity-based brain atlases from individual connectomes. The proposed methods exploit a previously proposed dense connectivity representation, termed continuous connectivity, by first performing graph-based hierarchical clustering of individual brains, and subsequently a…
In this paper, the task-related fMRI problem is treated in its matrix factorization formulation, focused on the Dictionary Learning (DL) approach. The new method allows the incorporation of a priori knowledge associated both with the experimental design as well as with available brain Atlases. Moreover, the proposed me…
Good atlases are defined for effective orbifolds, and a spark complex is constructed on each good atlas. It is proved that this process is 2-functorial with compatible systems playing as morphisms between good atlases, and that the spark character 2-functor factors through this 2-functor.
We give a definition of atlases for ineffective orbifolds, and prove that this definition leads to the same notion of orbifold as that defined via topological groupoids.
Starting with some motivating examples (classical atlases for a manifold, space of leaves of a foliation, group orbits), we propose to view a Lie groupoid as a generalized atlas for the "virtual structure" of its orbit space, the equivalence between atlases being here the smooth Morita equivalence. This "structure" kee…
Resting-state functional Magnetic Resonance Imaging (R-fMRI) holds the promise to reveal functional biomarkers of neuropsychiatric disorders. However, extracting such biomarkers is challenging for complex multi-faceted neuropatholo-gies, such as autism spectrum disorders. Large multi-site datasets increase sample sizes…
Finding the biomarkers associated with ASD is helpful for understanding the underlying roots of the disorder and can lead to earlier diagnosis and more targeted treatment. A promising approach to identify biomarkers is using Graph Neural Networks (GNNs), which can be used to analyze graph structured data, i.e. brain ne…
The specificty and sensitivity of resting state functional MRI (rs-fMRI) measurements depend on pre-processing choices, such as the parcellation scheme used to define regions of interest (ROIs). In this study, we critically evaluate the effect of brain parcellations on machine learning models applied to rs-fMRI data. O…
We study the number of Darboux charts needed to cover a closed connected symplectic manifold , and effectively estimate this number from below and from above in terms of the Lusternik--Schnirelmann category of and the Gromov width of .
We construct an infinite sequence of projectively flat manifolds by using castling transformations of prehomogeneous vector spaces. We also give a classification of manifolds equipped with a flat projective structure obtained by a finite number of castling transformations, and describe these flat projective structures …
The Jacobian conjecture is simplified using polynomial mappings.
Given the notion of suborbifold of the second author (based on ideas of Borzellino/Brunsden) and the classical correspondence (up to certain equivalences) between (effective) orbifolds via atlases and effective orbifold groupoids, we analyze which groupoid embeddings correspond to suborbifolds and give classes of subor…
New method uses entropy to generate multiple plausible causal maps.
Toric quasifolds extend toric geometry to non-rational polytopes.
We describe a bicategory of reduced orbifolds in the framework of classical differential geometry (i.e. without any explicit reference to notions of Lie groupoids or differentiable stacks, but only using orbifold atlases, local lifts and changes of charts). In order to construct such a …
New bridge between diffeology and noncommutative geometry.
Accumulation of standardized data collections is opening up novel opportunities for holistic characterization of genome function. The limited scalability of current preprocessing techniques has, however, formed a bottleneck for full utilization of contemporary microarray collections. While short oligonucleotide arrays …
In this paper we compute the minimal number of Darboux chart needed to cover a Hermitian symmetric space of compact type in terms of the degree of their embeddings in . The proof is based on the recent work of Y. B. Rudyak and F. Schlenk [18] and on the symplectic geometry tool developed by the first au…
DET unifies geometric and functional alignment for high-dimensional scientific data.
Currently, the diagnosis of Autism Spectrum Disorder (ASD) is dependent upon a subjective, time-consuming evaluation of behavioral tests by an expert clinician. Non-invasive functional MRI (fMRI) characterizes brain connectivity and may be used to inform diagnoses and democratize medicine. However, successful construct…
We study the minimal number C(M,ξ) of contact charts that one needs to cover a closed connected contact manifold (M,ξ). Our basic result is C(M,ξ) \le \dim M + 1. We compute C(M,ξ) for all closed connected contact 3-manifolds: C (M,ξ) = 2 if M = S^3 and ξis tight, 3 if M = S^3 and ξis overtwisted or if M = #_k (S^2 \ti…
Local semi-supervised method improves brain tissue classification in child MRI.
DBGDGM models dynamic brain graphs for better understanding brain function.
Deep learning models brain deformations based on atrophy and growth data.
Brain decoding is a popular multivariate approach for hypothesis testing in neuroimaging. It is well known that the brain maps derived from weights of linear classifiers are hard to interpret because of high correlations between predictors, low signal to noise ratios, and the high dimensionality of neuroimaging data. T…
Brain tumor segmentation from Magnetic Resonance Images (MRIs) is an important task to measure tumor responses to treatments. However, automatic segmentation is very challenging. This paper presents an automatic brain tumor segmentation method based on a Normalized Gaussian Bayesian classification and a new 3D Fluid Ve…
Extracts causal brain dynamics across multiple scales.
A new kernel measures brain network similarities, improving disease classification.
Resting-state functional MRI (rs-fMRI) in functional neuroimaging techniques have improved in brain disorders, dysfunction studies via mapping the topology of the brain connections, i.e. connectopic mapping. Since, there are the slight differences between healthy and unhealthy brain regions and functions, investigation…
New method aligns brain data across individuals for better brain decoding.
New method for analyzing brain dynamics using HMMs and graph models.
New method predicts AD progression using MEG brain networks.
Study uses simulation-based inference to decode brain activity from synthetic stimuli.
Brain-Computer Interface (BCI) uses brain signals in order to provide a new method for communication between human and outside world. Feature extraction, selection and classification are among the main matters of concerns in signal processing stage of BCI. In this article, we present our findings about the most effecti…
This research uses Siamese networks to identify partial mouse brain images from the Allen atlas.
Improving the interpretability of brain decoding approaches is of primary interest in many neuroimaging studies. Despite extensive studies of this type, at present, there is no formal definition for interpretability of brain decoding models. As a consequence, there is no quantitative measure for evaluating the interpre…
Study confirms sparse coding in whole brain using MRI data.
Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further establish the credentials of "brain-predicted age" as a biomarker of individual differe…
Generative model predicts multiple brain graphs from one, preserving topology.
The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and compared the FC variability across brain regions between typical, healthy subjects …
New methods improve brain data analysis from fMRI datasets.
fMRI semantic category understanding using linguistic encoding models attempts to learn a forward mapping that relates stimuli to the corresponding brain activation. State-of-the-art encoding models use a single global model (linear or non-linear) to predict brain activation given the stimulus. However, the critical as…
There has been huge interest in studying human brain connectomes inferred from different imaging modalities and exploring their relationship with human traits, such as cognition. Brain connectomes are usually represented as networks, with nodes corresponding to different regions of interest (ROIs) and edges to connecti…
Understanding the connectivity in the brain is an important prerequisite for understanding how the brain processes information. In the Brain/MINDS project, a connectivity study on marmoset brains uses two-photon microscopy fluorescence images of axonal projections to collect the neuron connectivity from defined brain r…
fMRI semantic category understanding using linguistic encoding models attempt to learn a forward mapping that relates stimuli to the corresponding brain activation. Classical encoding models use linear multi-variate methods to predict the brain activation (all voxels) given the stimulus. However, these methods essentia…
SFCNeXt estimates brain age from small MRI datasets.