Domain Elastic Transform: Bayesian Function Registration for High-Dimensional Scientific Datastat.ML
DET unifies geometric and functional alignment for high-dimensional scientific data.
problem Challenges in nonrigid registration for high-dimensional, irregular data.
method Domain Elastic Transform (DET) treats data as functions on irregular domains, using a Bayesian framework for elastic motion registration.
result DET achieves 92% topological preservation on MERFISH data and successfully registers whole-embryo Stereo-seq atlases.