This study improves valuation of post-revenue biopharmaceutical assets using Pfizer's data.
problem Accurate valuation of post-revenue drug assets in biotech and pharma.
method Historical sales data analysis to forecast future sales and calculate Net Present Value.
result Demonstrates a method for more informed investment decisions in biotech and pharma.
Optimized biopharmaceutical seed train design reduces variability and saves time.
problem Designing robust biotechnological processes with cell cultures.
method Coupling uncertainty-based upstream simulation and Bayes optimization using Gaussian processes.
result Optimized seed train design results in lower cell density variability and reduced process duration.
RAPTOR-GEN accelerates digital twin development for biopharmaceuticals.
problem Lack of agility in rapid, on-demand production of biotherapeutics due to bioprocess complexity.
method Bayesian learning framework based on a multi-scale probabilistic knowledge graph (pKG) and stochastic differential equations (SDE).
result RAPTOR-GEN accelerates intelligent digital twin development from sparse and heterogeneous experimental data.
Optimizes harvesting in biopharmaceutical fermentation with limited data.
problem High variability in fermentation outputs due to model risk with small data.
method Stochastic model, Bayesian approach, Markov decision process.
result Improves fermentation output and reduces variability.
Adaptive orthogonalization of data for clustering and visualization.
problem Clustering and visualization of data with high specificity.
method Adaptive orthogonalization process using Gromov-Wasserstein feedback.
result Method refines orthogonality of data to achieve high specificity clustering.
Paper introduces new actuarial-consistent valuations for insurance liabilities.
problem Valuation of insurance liabilities considering both financial and actuarial risks.
method Proposes two-step actuarial valuations and actuarial-consistent procedures.
result Actuarial-consistent valuations are equivalent to two-step actuarial valuations under coherence.
Paper recovers uncertainty from dynamic valuation rules.
problem Recovering latent uncertainty from observable valuation rules.
method Developed procedures to identify and characterize uncertainty structures from valuation rules.
result Valuation rules contain sufficient information to identify and recover uncertainty structures.
Study convolution of invariant valuations on Lie groups.
problem Understanding convolution of valuations on Lie groups.
method Explicit formula for left-invariant valuations, showing existence of smooth bi-invariant valuations, defining convolution on arbitrary Lie groups.
result Unified convolution operations on Lie groups.
SL(n) covariant valuations on Orlicz spaces are represented and characterized.
problem Representing SL(n) covariant valuations on Orlicz spaces.
method Representation theorem established for continuous, SL(n) covariant vector-valued valuations.
result Unique characterization of SL(n) covariant valuations as moment vectors.
Market valuation duration is 175 years, but drops to 46 years during crises.
problem Understanding the duration of market valuation and its impact on returns.
method Comparing market valuation ratios and dividends to estimate duration, analyzing the discount rate effect.
result Valuation duration is negatively correlated with market returns, with a robust out-of-sample R2 of 15%.
Paper simplifies default process modeling and credit valuation.
problem Modeling and pricing derivative securities with credit risk.
method Integrates default process, probability, and correlation into a unified framework.
result Risky valuation is Martingale in the proposed model.
Business cycles affect startup valuations, both directly and indirectly.
problem How do business cycles impact startup valuations?
method Structural Equation Model approach using a dataset of 1,089 venture capital investments.
result Business cycles impact startup valuations both directly and indirectly.
Classification of SL(n) covariant valuations on Orlicz spaces.
problem Classifying continuous SL(n) covariant valuations on Orlicz spaces.
method Complete classification without symmetric assumptions, focusing on moment matrix and a new functional in dimension two.
result The moment matrix is the only SL(n) covariant valuation for n≥3, and a new functional appears in dimension two.
We prove new kinematic formulas for tensor valuations and simplify previously known Crofton formulas by using the recently developed algebraic theory of translation invariant valuations. The heart of the paper is the computation of the Alesker-Fourier transform on the large class of spherical valuations, which is achie…
Classifies contravariant matrix-valued valuations on polytopes without continuity assumptions.
problem Classifying contravariant matrix-valued valuations on polytopes without continuity assumptions.
method Complete classification of contravariant matrix-valued valuations on polytopes in Rn without continuity assumptions. result The only such valuation is the general Lutwak-Yang-Zhang matrix in dimension n≥4, and a new function in dimension 3. Let SO+(p,q) denote the identity connected component of the real orthogonal group with signature (p,q). We give a complete description of the spaces of continuous and generalized translation- and SO+(p,q)-invariant valuations, generalizing Hadwiger's classification of Euclidean isometry-invari…
Study evaluates valuation models for UK companies using case studies.
problem Determining how accounting numbers affect business value.
method Comprehensive review of three valuation models: FCFVM, REVM, AEGM.
result Accounting numbers through valuation models can affect business value.
This paper proposes a paradigm shift in the valuation of long term annuities, away from classical no-arbitrage valuation towards valuation under the real world probability measure. Furthermore, we apply this valuation method to two examples of annuity products, one having annual payments linked to a mortality index and…
This paper provides intuition on the relationship of accrual and mark-to-market valuation for cash and forward interest rate trades. Discounted cashflow valuation is compared to spread-based valuation for forward trades, which explains the trader's view on valuation. This is followed by Taylor series approximation for …
The classification of continuous, translation invariant Minkowski valuations which are contravariant (or covariant) with respect to the complex special linear group is established in a 2-dimensional complex vector space. Every such valuation is given by the sum of a valuation of degree of homogeneity 1 and 3. In dimens…
Computes tube formulas for valuations in complex space forms.
problem Computing values of valuations on complex space forms.
method Develops tube formulas for valuations in complex space forms and generalizes classical formulas.
result Generalizes classical formulas of Weyl, Gray and others.
This paper addresses credit valuation adjustment with a new closeout convention.
problem Accurate estimation of financial claim value considering counterparty credit risk.
method Theoretical and computational analysis of a nonlinear valuation system using neural networks.
result A neural network-based algorithm effectively solves the high-dimensional nonlinear valuation system.
Classifies SL(n) covariant matrix-valued valuations on Lp-spaces.
problem Classifying SL(n) covariant matrix-valued valuations on Lp-spaces.
method Established a complete classification for continuous and SL(n) covariant matrix-valued valuations on Lp(Rn,|x|2dx), eliminating matrix symmetry assumption.
result Unique characterization of such valuations by the moment matrix in n>2, rotation matrix in 2D.
Existence of smooth valuations on subspaces is shown for certain conditions.
problem Existence of smooth valuations on subspaces with given restrictions.
method Analyzing compatibility and using recursive descriptions of the cosine transform.
result Compatibility is sufficient for extensibility in certain regimes.
Develops a new method to study algebraic tangent cones of sheaves using valuations.
problem Analyzing tangent cones of torsion-free sheaves on algebraic varieties.
method Introduces a slope stability theory and uses it to define a canonical tangent cone for quasi-regular valuations.
result Shows the existence of a canonical tangent cone for torsion-free sheaves, up to equivalence.
We give an explicit classification of translation-invariant, Lorentz-invariant continuous valuations on convex sets. We also classify the Lorentz-invariant even generalized valuations.
We study the properties of the multiplicative structure on valuations on convex sets. We prove a new version of the hard Lefschetz theorem for even translation invariant continuous valuations, and discuss related problems of integral geometry. Then we formulate a conjectural analogue of this result for odd valuations.
Fair market valuations ignore future worker profits in employee-owned firms.
problem Ignoring future worker profits in fair market valuations for employee-owned firms.
method Analyzing property rights and residual claimants in employee-owned firms.
result Fair market valuations are inappropriate for employee-owned firms.
A description of continuous rigid motion compatible Minkowski valuations is established. As an application, we present a Brunn-Minkowski type inequality for intrinsic volumes of these valuations.
We introduce the new notion of convolution of a (smooth or generalized) valuation on a group G and a valuation on a manifold M acted upon by the group. In the case of a transitive group action, we prove that the spaces of smooth and generalized valuations on M are modules over the algebra of compactly supported g…
Enhances data valuation by integrating global and local statistical properties.
problem Insufficient consideration of global and local statistical properties in data valuation methods.
method Proposes a method that fuses global and local statistical properties into regularization terms for Shapley value estimation and dynamic data valuation.
result Demonstrates improved performance and efficiency of data valuation methods through integration of global and local statistical properties.
Study reveals which startup valuation factors are most critical.
problem Understanding the complex factors influencing startup valuations.
method Hierarchical prediction models using decision trees and random forests.
result Identifies which factors most significantly impact startup valuations.
In this paper, we endow the space of continuous translation invariant valuation on convex sets generated by mixed volumes coupled with a suitable Radon measure on tuples of convex bodies with two appropriate norms. This enables us to construct a continuous extension of the convolution operator on smooth valuations to n…
We study the space of generalized translation invariant valuations on a finite-dimensional vector space and construct a partial convolution which extends the convolution of smooth translation invariant valuations. Our main theorem is that McMullen's polytope algebra is a subalgebra of the (partial) convolution algebra …
Researchers classify and decompose valuations on convex functions.
problem Classifying valuations on convex functions.
method Geometric decomposition of valuations, using properties of special subspaces and Monge-Ampère-type operators.
result Valuations decompose into subspaces defined by vanishing properties.
A complete classification of all continuous GL(n) contravariant Minkowski valuations is established. As an application we present a family of sharp isoperimetric inequalities for such valuations which generalize the classical Petty projection inequality.
New space for valuations in non-Archimedean setting with duality properties.
problem Developing a non-Archimedean analogue of classical valuation spaces.
method Construction of a new space of valuations with similar structures to classical spaces.
result The new space satisfies Poincaré duality and hard Lefschetz theorem.
OpenDataVal benchmarks data valuation algorithms for diverse datasets.
problem Improving model performance and mitigating biases in training datasets.
method Unified benchmark framework for data valuation algorithms.
result No single algorithm performs uniformly best across all tasks.
FGSV defends against shell company attacks in group data valuation.
problem Shell company attacks on group-level data valuation.
method Developed a provably fast and accurate approximation algorithm for FGSV.
result Empirical results show significant improvement in computational efficiency and accuracy.
Obtaining more accurate equity value estimates is the starting point for stock selection, value-based indexing in a noisy market, and beating benchmark indices through tactical style rotation. Unfortunately, discounted cash flow, method of comparables, and fundamental analysis typically yield discrepant valuation estim…
The decomposition of the space of continuous and translation invariant valuations into a sum of SO(n) irreducible subspaces is obtained. A reformulation of this result in terms of a Hadwiger type theorem for continuous translation invariant and SO(n)-equivariant tensor valuations is also given. As an application, symme…
This article is the third part of the series of articles where the theory of valuations on manifolds is constructed. In math.MG/0503399 the notion of a smooth valuation on a manifold was introduced. The goal of this article is to put a canonical multiplicative structure on the space of smooth valuations on general mani…
We obtain new general results on the structure of the space of translation invariant continuous valuations on convex sets (a version of the hard Lefschetz theorem). Using these and our previous results we obtain explicit characterization of unitarily invariant translation invariant continuous valuations. It implies new…
New Orlicz Brunn-Minkowski inequalities are established for rigid motion compatible Minkowski valuations of arbitrary degree. These extend classical log-concavity properties of intrinsic volumes and generalize seminal results of Lutwak and others. Two different approaches which refine previously employed techniques are…
New method reduces CVA-VaR computation complexity.
problem Efficiently estimating CVA-VaR for financial risk management.
method Multilevel nested simulation for probabilities.
result 3 orders of magnitude reduction in computational complexity.
We study convex risk measures describing the upper and lower bounds of a good deal bound, which is a subinterval of a no-arbitrage pricing bound. We call such a convex risk measure a good deal valuation and give a set of equivalent conditions for its existence in terms of market. A good deal valuation is characterized …
A Kalman filter reduces valuation risk in business valuation models.
problem Reducing valuation risk in business valuation models.
method Recursive FCFF model with Kalman filtering to adjust WACC.
result Significant reduction in valuation risk by implementing Kalman filter.
Optimal pricing strategy for unknown valuation models with noisy feedback.
problem Minimizing regret in dynamic pricing with unknown valuation functions and noisy feedback.
method Proposes a minimax-optimal algorithm using discretization and data partitioning to handle unknown noise distribution and Lipschitz continuity of valuation functions.
result Achieves minimax-optimal regret bound matching the theoretical lower bound up to logarithmic factors.