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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

169,341 papers · 148 categories

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0111 · Apr 201819922001200920182026
5 results for benefit-risk

Unified framework estimates desirability of outcome ranking for benefit-risk evaluation.

problem Estimating desirability of outcome ranking in randomized and observational studies.
method Unified covariate-adjusted causal inference framework, estimating conditional ordinal distributions through sequential risk-set hazards, and deriving efficient influence function (EIF).
result CVTMLE-SL showed strongest performance across various settings.

Unified framework for optimizing treatment quantiles considering risk and efficacy.

problem Maximizing treatment outcomes while controlling risk in sequential clinical decisions.
method Risk-Aware Quantile Dynamic Treatment Regimes (RQDTR) framework that optimizes a prespecified quantile of the cumulative potential outcome while incorporating treatment-related risk.
result Improves tail-oriented efficacy and achieves more favorable benefit-risk trade-offs compared to existing methods.

Insurance benefits risk sharing for finite mean risks but not for infinite mean risks.

problem The effect of risk sharing and diversification for infinite mean risks.
method Investigation of risk sharing and diversification for infinite mean models, including stable, Pareto, and Fréchet distributions.
result Risk sharing can have a negative effect for infinite mean models, a phenomenon known as the nondiversification trap.

AI enhances personalized drug development and decision-making in pharma.

problem Traditional drug development lacks personalized treatment plans.
method Application of AI in drug discovery, clinical trials, and post-marketing assessment.
result AI improves personalized medicine, optimizing health outcomes.