Study optimizes experimental design for best treatment arm identification.
problem Identifying the best treatment arm given contextual information.
method Adaptive Sampling-Policy Learning (PLAS) strategy for minimax rate optimality.
result PLAS strategy achieves minimax rate optimality in expected simple regret.
Q-learning adapted to find near-equivalent treatment strategies.
problem Finding optimal treatment sequences in dynamic treatment regimes.
method Introducing a worst-value tolerance criterion to find sets of near-equivalent policies.
result Constructs families of near-equivalent treatment strategies.
Estimates RL data for dynamic treatment effects using GMM.
problem Estimating dynamic treatment effects from RL data with nonstationary behavior policies.
method Weighted GMM approach to stabilize variance in adaptive RL settings.
result Valid hypothesis testing and confidence regions for dynamic treatment effects.
Develops deep jump learning for continuous treatment OPE.
problem Estimating mean outcomes under new treatment rules using historical data from different rules.
method Adaptive deep discretization of continuous treatment space using deep learning and multi-scale change point detection.
result Validated method through theoretical results, simulations, and real application to Warfarin Dosing.
New method improves treatment effect estimation in adaptive experiments with noncompliance.
problem Estimating average treatment effect in adaptive experiments with binary instrumental variable.
method AMRIV estimator that balances outcome noise and compliance variability.
result AMRIV achieves semiparametric efficiency bound and is robust to noncompliance.
New method for estimating counterfactual means in adaptive experiments.
problem Inference for counterfactual means in sequentially designed experiments with adaptive treatment policies.
method Latent factor model and nearest neighbors method for estimation.
result Asymptotically valid confidence intervals for counterfactual means established.
Develops a new RL algorithm for medical treatment regimes.
problem Optimal dose determination in continuous action environments.
method Quasi-optimal learning algorithm for near-optimal actions.
result Guaranteed convergence and effectiveness in real applications.
The paper improves DR estimators for off-policy evaluation in contextual bandits.
problem Challenges in evaluating policies with adaptively collected data.
method Adaptive weighting to control variance in DR estimators.
result Improved t-statistic based on the estimator is asymptotically normal.
EHR-MPC optimizes sepsis treatment using digital twins and inference-time control.
problem Optimal sepsis treatment policies are contested and difficult to adapt during inference.
method EHR-MPC decouples learning patient dynamics from treatment optimization, enabling inference-time control over learned digital twins.
result EHR-MPC achieves comparable off-policy performance and improved simulation performance compared to RL baselines.
Dynamic treatment strategies on networks amplify policy impact through spillovers.
problem Effective dynamic treatment allocation in network settings.
method Q-Ising, a three-stage pipeline integrating Bayesian dynamic Ising model, treatment adoption histories, and offline reinforcement learning.
result Adaptive targeting outperforms static centrality benchmarks in Indian village microfinance networks and synthetic data.
New method uses online learning to improve AIPW estimators for adaptively collected data.
problem Estimating treatment effects with adaptively collected data.
method Online learning to minimize sequentially weighted estimation error.
result Local minimax lower bound shows optimality of AIPW estimator.
The paper develops deep learning models for personalized treatment rules in survival analysis.
problem Deriving optimal treatment rules for bivariate survival outcomes in randomized trials.
method Adaptive prediction-powered learning using deep neural networks and stochastic policies.
result Maximizes joint survival probability beyond fixed time points (t1,t2). Efficient inference method for adaptive experiments with tighter confidence sequences.
problem Efficient inference of Average Treatment Effect in a changing policy sequential experiment.
method Semiparametric efficient inference using Adaptive Augmented Inverse-Probability Weighted estimator and asymptotic confidence sequences.
result Derives tighter confidence sequences for adaptive experiments under data-dependent stopping times.
POLAR optimizes treatment strategies in dynamic settings with statistical guarantees.
problem Optimizing sequential decisions in dynamic treatment regimes with robustness and statistical guarantees.
method Pessimistic model-based approach estimating transition dynamics and incorporating uncertainty penalties.
result Offers statistical and computational guarantees, including finite-sample bounds on policy suboptimality.
Algorithm learns interference network and optimizes treatment allocation for unknown network effects.
problem Adaptive experimentation under unknown network interference.
method Thompson sampling algorithm with Gibbs sampler for joint learning of interference network and treatment allocation.
result Proves a Bayesian regret bound and achieves sublinear regret in real-world applications.
Paper optimizes experimental design for estimating treatment effect.
problem Estimating treatment effect with heterogeneous subjects and treatments.
method Adaptive experimental design incorporating bandit learning.
result Demonstrates optimality of proposed adaptive experiment framework.
Proposes pT-Learning for optimal dynamic treatment regimes in mHealth.
problem Challenges in learning optimal dynamic treatment regimes with large intervention options and infinite time horizon.
method Proximal Temporal consistency Learning (pT-Learning) framework for adaptively adjusting between deterministic and stochastic policies.
result Minimax estimator avoids double sampling issue and can incorporate off-policy data.
GAMBITTS uses GenAI for adaptive interventions, improving decision-making.
problem Adaptive interventions with GenAI-generated content.
method Generator-mediated bandit-Thompson sampling (GAMBITTS).
result GAMBITTS outperforms standard bandit methods in mobile health interventions.
New framework for adaptive clinical trials to address real-world challenges.
problem Real-world challenges in post-regulatory clinical trials.
method RFAN framework integrating regulatory constraints and treatment policy value.
result Empirical evaluation of RFAN's performance.
IntelligentPooling learns personalized mHealth policies from limited data.
problem Challenges in personalizing mHealth policies with limited user data and noise.
method Adaptive use of other users' data to learn personalized policies.
result Achieves 26% lower regret compared to state-of-the-art approaches.
Adapting policy learning for data collected from evolving systems.
problem Challenges in learning optimal policies from adaptively collected data.
method Proposes an algorithm based on generalized augmented inverse propensity weighted (AIPW) estimators to control worst-case estimation variance.
result Achieves minimax rate optimal regret guarantees even with diminishing exploration.
Proposes a method to avoid excessive exploration in reinforcement learning.
problem Avoiding excessive exploration in reinforcement learning to deploy it in practice.
method Designs a novel algorithm using UCB reinforcement learning policy with adaptive exploration constraints.
result Proves that the approach remains conservative while minimizing regret in tabular settings and validates on real-world tasks.
The paper proposes a new policy for optimal treatment allocation based on quantile treatment effects.
problem Optimal treatment allocation policies that target distributional welfare, especially when individuals are heterogeneous.
method The approach involves allocating treatments based on the conditional quantile of individual treatment effects (QoTE), considering both prudent and negligent policymakers.
result The proposed minimax policies are robust to model uncertainty and can be generalized to various settings.
Study optimal treatment assignment policies under strategic agent responses.
problem Learning optimal treatment policies with strategic agents complicates estimation.
method Dynamic model with threshold convergence to mean-field equilibrium, consistent estimator for policy gradient.
result Threshold for treatment assignment converges to mean-field equilibrium threshold under large but finite number of agents.
Three approaches learn personalized treatment policies for UTI patients.
problem Learning optimal treatment policies in multiobjective settings with fully observed outcomes.
method Indirect and direct approaches using predictive models and without intermediate models.
result All approaches outperform clinicians in achieving better performance on all outcomes and trade-offs.
Paper develops methods for evaluating mHealth interventions using historical data.
problem Evaluating the long-term effectiveness of mHealth interventions designed for near-term outcomes.
method Develops off-policy estimation techniques to infer long-term average outcomes from historical data.
result Provides estimators and confidence intervals for evaluating mHealth policies.
Mobile apps and machine learning improve malaria prevention and treatment.
problem High malaria cases and deaths in low-income countries.
method Adaptive interventions using mobile health apps and machine learning.
result Increased malaria testing, adherence, and provider skills.
Estimates and infers multi-stage stationary treatment policies with variable selection.
problem Valid inference for multi-stage stationary treatment policies with high-dimensional feature variables.
method Estimate the value function using augmented inverse probability weighted estimator, apply penalty for variable selection, construct one-step improvements for valid inference.
result Improved estimators are asymptotically normal, valid inference for policy parameters demonstrated.
Paper proposes ClipSMT algorithm for better ATE estimation.
problem Adaptive estimation of Average Treatment Effect (ATE).
method ClipSMT algorithm for improved Neyman regret.
result Achieves exponential improvements in Neyman regret.
Proposes a new method to estimate continuous treatment policies and match treatments effectively.
problem Current methods struggle with continuous treatment policies and complex matching.
method Formulates treatment effectiveness as a parametrizable model, using deep learning for optimization.
result Significant improvement in treatment effectiveness and matching efficiency.
Develops adaptive framework for estimating survival effects with censoring.
problem Estimating causal effects in survival data with censoring.
method Derives semiparametric efficiency bound, proposes efficiency-optimal allocation policy, and develops Adaptive Survival Estimator (ASE).
result ASE achieves asymptotic normality via martingale central limit theorem and demonstrates efficiency gains over uniform randomization.
The paper develops methods to estimate optimal treatment sequences under policy constraints.
problem Estimating the best sequence of treatments over multiple stages for individuals.
method Empirical welfare maximization approach, solving treatment assignment sequentially or simultaneously.
result Established convergence rates and upper bounds for estimation methods.
AACE learns treatment policies from EHRs using annotations to improve accuracy.
problem Learning treatment policies from multimodal EHRs with bias and inefficiency.
method Annotation-assisted coarsened effects (AACE) method.
result AACE outperforms existing methods in predicting treatment benefit from multimodal EHRs.
Study optimal and equitable encouragement policies for treatment adherence.
problem Optimal treatment adherence policies in the presence of human non-adherence.
method Covariate-conditional no-direct-effect model of encouragement; tractable policy characterizations under constraints.
result Induced treatment take-up is the fairness target, not recommendation rates.
We study the problem of policy evaluation and learning from batched contextual bandit data when treatments are continuous, going beyond previous work on discrete treatments. Previous work for discrete treatment/action spaces focuses on inverse probability weighting (IPW) and doubly robust (DR) methods that use a reject…
Adaptive inference for M-estimators in bandit data with model misspecification.
problem Challenges in off-policy inference for adaptively collected bandit data with a misspecified model.
method A novel approach to define a projected solution over a stationary evaluation policy, stabilizing variance with flexible methods.
result Valid inference for M-estimators in adaptive settings, even with unstable treatment policies. CADR estimator improves inference for contextual bandit data.
problem Valid inference on contextual bandit data.
method CADR estimator for policy value, addressing adaptive data collection challenges.
result CADR provides correct coverage of confidence intervals.
The paper learns personalized treatment rules from observational data.
problem Developing effective treatment policies for individual patients.
method Contextual bandit approach to minimize expected risk of treatment policies.
result The proposed method outperforms physicians and baseline approaches in IV and VP administration.
Method learns optimal treatment sequences from observational data.
problem Optimal dynamic treatment regimes for public policies and medical interventions.
method Doubly robust classification-based approach via backward induction.
result Achieves optimal convergence rate of n^(-1/2) for welfare regret.
Paper derives policy rules from observational data for hepatitis C treatment.
problem Improving treatment guidelines for HIV/HCV co-infected patients.
method Weighted K-means algorithm for estimating CATEs, decision tree implementation.
result Identifies a subgroup with high spontaneous HCV clearance rate.
The paper addresses statistical inference issues in adaptive experiments.
problem Statistical inference problems in adaptive experiments.
method Explains and fixes statistical inference issues in adaptive experiments using various methods.
result Various methods to stabilize inferences and recover asymptotic normality.
Proposes a fusion method for many treatment groups in ITRs.
problem Challenges in handling many treatment groups with data sparsity and covariate imbalance.
method Calibration-weighted treatment fusion procedure that balances covariates and fuses similar treatments.
result Ensures robust treatment group recovery and policy value compared to existing methods.
Proposes fair and robust methods for estimating treatment effects.
problem Estimating treatment effects while maintaining fairness.
method Simple, nonparametric framework with fairness constraints.
result Estimators are double robust and characterize welfare trade-offs.
In treatment allocation problems the individuals to be treated often arrive sequentially. We study a problem in which the policy maker is not only interested in the expected cumulative welfare but is also concerned about the uncertainty/risk of the treatment outcomes. At the outset, the total number of treatment assign…
Optimal adaptive experiment for choosing best treatment with binary outcomes.
problem Choosing the best treatment from binary options in an adaptive experiment.
method Adaptive experiment with two phases: treatment allocation and choice. Neyman allocation method used.
result Neyman allocation is minimax and Bayes optimal, matching lower bounds for regret.
The paper proposes an interpretable off-policy learning algorithm for medical treatments.
problem Lack of interpretable methods for personalized treatment decisions from observational data.
method Hyperbox search approach for interpretable policies in disjunctive normal form.
result The proposed algorithm outperforms state-of-the-art methods in terms of regret and is rated highly interpretable by clinical experts.
This work addresses causal inference challenges in networked interference and proposes GNN-based estimators for individual treatment effects.
problem Estimating individual treatment effects in randomized experiments with networked interference.
method Uses Graph Neural Networks (GNNs) to capture network dependencies and derive causal effect estimators.
result Provides policy regret bounds and heuristic error bounds for GNN-based causal estimators under network interference and treatment capacity constraints.
End-to-end policy learning method improves CATE estimation.
problem Learning optimal treatment policies from partially observed data.
method Modified causal forest for policy learning.
result Maximizing policy value is equivalent to minimizing CATE.