Bayesian optimization improves classifier selection for acute infection and mortality.
problem Improving accuracy of acute infection and mortality prediction.
method Comparison of hyperparameter optimization methods (grid search, random sampling, Bayesian optimization).
result Bayesian optimization outperforms grid search or random sampling for in-hospital mortality classifiers.
Study uses machine learning to optimize antibiotic therapy for MRSA skin infections.
problem Optimizing antibiotic choice for MRSA skin infections due to reduced treatment options and side effects.
method Propensity score matching, machine learning models (SVM, RF, LASSO), counterfactual analysis.
result RF model shows stronger treatment heterogeneity and potential for therapy change.
Acute respiratory infections have epidemic and pandemic potential and thus are being studied worldwide, albeit in many different contexts and study formats. Predicting infection from symptom data is critical, though using symptom data from varied studies in aggregate is challenging because the data is collected in diff…
Although timely sepsis diagnosis and prompt interventions in Intensive Care Unit (ICU) patients are associated with reduced mortality, early clinical recognition is frequently impeded by non-specific signs of infection and failure to detect signs of sepsis-induced organ dysfunction in a constellation of dynamically cha…
Study reveals hidden infections and infection dynamics from early data.
problem Understanding early infection dynamics and hidden infections in COVID-19.
method Data-driven machine learning analysis focusing on infection counts over time.
result Significant asymptomatic infections, 10-day lag, and strong infectious force.
Model predicts real-time job applicant numbers for regional economic analysis.
problem Real-time economic analysis using alternative data.
method Mixed-Frequency Aggregate Learning (MF-AGL) model.
result Model accurately predicts regional labor market conditions and economic status changes.
Proof of Gromov's theorem on convex polytopes with acute angles.
problem Gromov's conjecture on extremal scalar curvature of convex polytopes.
method Smoothing construction using Dirac operator techniques.
result Detailed proof of Gromov's theorem.
A new model characterizes undocumented and asymptomatic infections to quantify COVID-19 uncertainties.
problem Quantifying uncertainties in COVID-19 infections and contagion.
method SUDR model: characterizes undocumented and documented infections, captures probabilistic density, and incorporates Bayesian inference.
result Demonstrates deeper understanding of COVID-19 uncertainties compared to classic models.
Study on Teichmüller space of acute triangles using explicit calculations.
problem Analogue of Thurston's metric on acute triangles.
method Direct calculation of distance function and Finsler structure.
result Explicit expressions and properties of the metric on acute triangles.
AI system predicts acute critical illness from EHRs with explainability.
problem Lack of clinical interpretability in AI predictions for acute critical illness.
method Developed an explainable AI early warning score (xAI-EWS) system.
result System provides clinicians with insights into EHR data explaining predictions.
Study develops a dynamic risk model for COVID-19 mortality using UK Biobank data.
problem Developing tools to monitor high-risk patients during the COVID-19 pandemic.
method Data-driven random forest classification model using baseline characteristics and symptoms.
result Model predicts COVID-19 mortality with excellent performance (AUC: 0.91), identifying novel predictors.
Satellite constructions on a knot can be thought of as taking some strands of a knot and then tying in another knot. Using satellite constructions one can construct many distinct isotopy classes of knots. Pushing this further one can construct distinct concordance classes of knots which preserve some algebraic invarian…
This study proposes a method to predict ICU infections from imbalanced data using clustering-based undersampling and ensemble classifiers.
problem Predicting healthcare-associated infections in ICU patients from imbalanced data.
method Clustering-based undersampling strategy combined with ensemble classifiers.
result The proposed method outperforms other resampling techniques in predicting ICU infections.
Bayesian methods improve group testing for identifying infected patients.
problem Identifying infected patients from group testing results with false positives.
method Bayesian inference and belief propagation algorithm, combined with expectation-maximization method.
result True-positive rate improved by considering credible intervals.
CRISP predicts individual-level COVID-19 risk based on contact data.
problem Estimating individual-level infection risk during the pandemic.
method Probabilistic graphical model using SEIR framework with contact data.
result Model accurately predicts infection spread and recovery times.
Modeling infection hotspots to quantify effects of contact tracing and testing.
problem Capturing the role of infection hotspots in disease transmission.
method Temporal point process modeling framework to represent visits and disease transmission.
result Estimation of transmission rates at sites and households using Bayesian optimization.
Deep learning identifies transcriptomic patterns and cell types associated with SARS-CoV-2 infection and COVID-19 severity.
problem Understanding how SARS-CoV-2 varies in infecting and causing severe COVID-19.
method Developed a new approach to generating self-supervised edge features, using Graph Attention Networks (GAT) and Set Transformer.
result Achieved state-of-the-art performance in predicting disease state of individual cells using single-cell RNA sequencing data.
Let C(L) be the right-angled Coxeter group defined by an abstract triangulation L of S2. We show that C(L) is isomorphic to a hyperbolic right-angled reflection group if and only if L can be realized as an acute triangulation. The proof relies on the theory of CAT(-1) spaces. A corollary is that an …
Paper proposes a new method for more accurate group testing of infected patients.
problem Identifying infected patients efficiently with reduced tests and corrected errors.
method Adaptive design of pools based on Bayesian posterior prediction using belief propagation algorithm.
result The proposed method results in more accurate identification of infected patients.
Maps between acute triangles with minimal stretch found and studied.
problem Finding the minimal stretch between acute triangles.
method Formula for the smallest Lipschitz constant and analysis of the metric space.
result Metric space of pairs of acute triangles with fixed area is Finsler and geodesics determined.
Detection of malware-infected computers and detection of malicious web domains based on their encrypted HTTPS traffic are challenging problems, because only addresses, timestamps, and data volumes are observable. The detection problems are coupled, because infected clients tend to interact with malicious domains. Traff…
Machine learning improves diagnostic test accuracy for bovine tuberculosis.
problem Improving diagnostic test sensitivity for bovine tuberculosis.
method Machine learning to assess risk landscapes and predict infection.
result Test sensitivity improved, detecting 240 more infected herds per year.
A time-dependent SIR model predicts COVID-19 spread and herd immunity.
problem Modeling and predicting COVID-19 spread and herd immunity.
method Time-dependent SIR model with 2 types of infected persons (detectable and undetectable).
result The model accurately predicts the turning point and herd immunity threshold.
Study repurposes open data to find potential COVID-19 drugs.
problem Developing effective treatments for COVID-19.
method Deep learning network-based approach using large scientific corpus.
result Identified 41 repurposable drugs for COVID-19.
The paper explores Kähler and anti-Kähler structures on quasi-statistical manifolds.
problem Investigating Kähler and anti-Kähler structures on quasi-statistical manifolds.
method Analyzing conditions for integrability of almost complex structures and defining Kähler and anti-Kähler manifolds.
result Conditions for (Nˊ,h,abla,L) to be an anti-Kähler manifold are identified. Improved rigidity of Delaunay triangulated plane.
problem Rigidity of Delaunay triangulated plane under discrete conformality.
method Modifying Wu's proof to weaken the uniformly acute condition to the uniformly Delaunay condition.
result Improved rigidity result for Delaunay triangulated plane.
New Milnor's invariant condition for topologically slice links.
problem Conditions for topologically slice links involving Milnor's invariant.
method Different Milnor's invariant condition to handle cases not covered by previous theorem.
result New sufficient conditions for topologically slice links.
LSTM models predict low likelihood of another COVID-19 wave in India.
problem Inaccurate and unreliable COVID-19 infection forecasting models due to data limitations and model complexity.
method Application of LSTM, bidirectional LSTM, and encoder-decoder LSTM models for multi-step infection forecasting.
result Predictions indicate low likelihood of another wave in October and November 2021.
Novel method combines neural network features with survival models for ICU infections.
problem Improving predictive models of ICU infections while maintaining interpretability.
method Semi-parametric approach combining low-resolution and high-resolution data.
result Improved predictive power with interpretability maintained.
Budney recently constructed an operad that encodes splicing of knots. He further showed that the space of (long) knots is generated over this operad by the space of torus knots and hyperbolic knots, thus generalizing the satellite decomposition of knots from isotopy classes to the level of the space of knots. Infection…
We consider the problem of learning the weighted edges of a graph by observing the noisy times of infection for multiple epidemic cascades on this graph. Past work has considered this problem when the cascade information, i.e., infection times, are known exactly. Though the noisy setting is well motivated by many epide…
In this paper, the development of a probabilistic network for the diagnosis of acute cardiopulmonary diseases is presented. This paper is a draft version of the article published after peer review in 2018 (https://doi.org/10.1002/bimj.201600206). A panel of expert physicians collaborated to specify the qualitative part…
Study developed phenotypes for ICU patients' brain dysfunction states.
problem Underdiagnosis of acute brain dysfunction in ICU patients.
method Created algorithms to quantify and cluster brain dysfunction states.
result Developed three phenotypes of ICU patients' brain dysfunction states.
Machine learning detects and diagnoses coughs for respiratory infections.
problem Detecting and diagnosing coughs for respiratory infections.
method Convolutional Neural Networks (CNNs) to detect cough events and diagnose three illnesses.
result Accuracy over 89% for detection and diagnosis.
Background: Fluctuating hearing loss is characteristic of Meniere's Disease (MD) during acute episodes. However, no reliable audiometric hallmarks are available for counselling the hearing recovery possibility. Aims/Objectives: To find parameters for predicting MD hearing outcomes. Material and Methods: We applied mach…
Study of influenza A virus spread using mathematical equations.
problem Understanding the spread of influenza A virus infection.
method Mathematical model and analysis of dynamical system.
result Surface trajectories and asymptotic behavior of the system.
New group testing method uses Belief Propagation for accurate screening.
problem Efficiently identifying infected samples in large groups with minimal tests.
method Belief Propagation algorithm for inference in group testing schemes.
result Significantly increased accuracy of infection identification with fewer tests.
Paper uses UKS to improve BLE RSSI for proximity inference in mobile phone apps.
problem Improper BLE RSSI for accurate proximity inference during pandemics.
method Single-dimensional Unscented Kalman Smoother (UKS) with Gaussian process observation transforms.
result UKS outperforms traditional methods in predicting infection risk from BLE RSSI.
Many works have been proposed in the literature to capture the dynamics of diffusion in networks. While some of them define graphical markovian models to extract temporal relationships between node infections in networks, others consider diffusion episodes as sequences of infections via recurrent neural models. In this…
The paper classifies Poincaré complexes as topological manifolds.
problem Classifying Poincaré complexes as topological manifolds.
method Using spherical fibrations and CW-complexes, the paper proves stability and homotopy equivalence.
result A sufficient condition for Poincaré complexes to be homotopy types of topological manifolds.
Epidemiological model updates infection rates in China, US, Italy.
problem Evaluate policy interventions for mitigating the 2019-nCov pandemic.
method Custom SITR model with variational data assimilation for real-time updates.
result Model robust to initial conditions, infers infection numbers and parameters.
We give an explicit construction of linearly independent families of knots arbitrarily deep in the (n)-solvable filtration of the knot concordance group using the ρ^1-invariant. A difference between previous constructions of infinite rank subgroups in the concordance group and ours is that the deepest infecting knots i…
It has been shown that the Alvarez-Gaumeˊ-Witten miraculous anomaly cancellation formula in type IIB superstring theory and its various generalizations can be derived from modularity of certain characteristic forms. In this paper, we show that the Green-Schwarz formula and the Schwarz-Witten formula i…
Study phase transitions in identifying infected individuals using group testing.
problem Identifying a set of k infected individuals from a population using pooled tests.
method Two random assignment designs (constant-column and Bernoulli) and polynomial-time inference procedures.
result Sharp phase transitions in statistical and computational limits for detection and recovery problems.
Large vessel occlusion (LVO) plays an important role in the diagnosis of acute ischemic stroke. Identifying LVO of patients in the early stage on admission would significantly lower the probabilities of suffering from severe effects due to stroke or even save their lives. In this paper, we utilized both structural and …
Backdoor attacks are found to be effective against robust machine learning models trained with PGD.
problem Injecting and defending against backdoor attacks in robust machine learning models.
method Study and detection of backdoor attacks on PGD-trained robust models using feature clustering.
result AEGIS effectively detects PGD-trained robust DNNs infected with backdoors with 91.6% accuracy.
Plane triangulations remain rigid under discrete conformal changes.
problem Rigidity of acute triangulations under discrete conformal changes.
method Maximum principles, discrete Liouville theorem, extremal lengths, Euclidean to hyperbolic discrete conformality.
result Uniformly acute triangulations are rigid under Luo's discrete conformal change.
We construct discrete and faithful representations into the isometry group of a hyperbolic space of the fundamental groups of acute negatively curved even-sided polygons of finite groups.