A novel validation method improves feature importance analysis in subject-specific ML models.
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A new method for efficient inference in sequential latent-variable models.
BrainSurfCNN predicts task contrasts from resting-state fingerprints, improving accuracy over baseline.
Framework integrates brain connectivity data for clinical predictions.
Neural network learns kernel functions for survival analysis and prediction intervals.
In neuroimaging data analysis, Gaussian graphical models are often used to model statistical dependencies across spatially remote brain regions known as functional connectivity. Typically, data is collected across a cohort of subjects and the scientific objectives consist of estimating population and subject-specific g…
LI-ITR combines flexible ML with interpretable approximations for personalized treatment rules.
Unified model combines neural networks and dictionary learning for clinical predictions from brain data.
Proposes a new DNN framework for count data with high-cardinality features.
Self-supervised method improves biosignal models with limited labeled data and subjects.
Model uses smartphone data to assess MS trajectories.
Novel framework predicts brain biomarker trajectories with superior performance.
The increasing availability of electrocardiogram (ECG) data has motivated the use of data-driven models for automating various clinical tasks based on ECG data. The development of subject-specific models are limited by the cost and difficulty of obtaining sufficient training data for each individual. The alternative of…
Many data-driven approaches exist to extract neural representations of functional magnetic resonance imaging (fMRI) data, but most of them lack a proper probabilistic formulation. We propose a group level scalable probabilistic sparse factor analysis (psFA) allowing spatially sparse maps, component pruning using automa…
Framework learns continuous dynamics from sparse trajectories.
Proposes a deep neural network for predicting clustered time-to-event data.
We harness the power of Bayesian emulation techniques, designed to aid the analysis of complex computer models, to examine the structure of complex Bayesian analyses themselves. These techniques facilitate robust Bayesian analyses and/or sensitivity analyses of complex problems, and hence allow global exploration of th…
There has been a lot of work fitting Ising models to multivariate binary data in order to understand the conditional dependency relationships between the variables. However, additional covariates are frequently recorded together with the binary data, and may influence the dependence relationships. Motivated by such a d…
We propose a method to predict the subject-specific longitudinal progression of brain structures extracted from baseline MRI, and evaluate its performance on Alzheimer's disease data. The disease progression is modeled as a trajectory on a group of diffeomorphisms in the context of large deformation diffeomorphic metri…
Pseudo healthy synthesis, i.e. the creation of a subject-specific `healthy' image from a pathological one, could be helpful in tasks such as anomaly detection, understanding changes induced by pathology and disease or even as data augmentation. We treat this task as a factor decomposition problem: we aim to separate wh…
A new method improves SSVEP BCI to recognize responses in sub-second time with high accuracy.
We introduce a mixed-effects model to learn spatiotempo-ral patterns on a network by considering longitudinal measures distributed on a fixed graph. The data come from repeated observations of subjects at different time points which take the form of measurement maps distributed on a graph such as an image or a mesh. Th…
Improved assessment of knee osteoarthritis using geodesic B-score.
New model extracts shared brain activity patterns from fMRI data.
End-to-end framework learns precise disparity for activity recognition.
A new method reduces dimensionality for better likelihood-free parameter estimation.
Single-trial classification of event-related potentials in electroencephalogram (EEG) signals is a very important paradigm of brain-computer interface (BCI). Because of individual differences, usually some subject-specific calibration data are required to tailor the classifier for each subject. Transfer learning has be…
PSLR classifies functional data with scalar covariates using path signatures.
Electroencephalographic (EEG) monitoring of neural activity is widely used for sleep disorder diagnostics and research. The standard of care is to manually classify 30-second epochs of EEG time-domain traces into 5 discrete sleep stages. Unfortunately, this scoring process is subjective and time-consuming, and the defi…
Proposes inference for DNNs in GNRMs, addressing non-independence issues.
We introduce a Bayesian nonparametric regression model for data with multiway (tensor) structure, motivated by an application to periodontal disease (PD) data. Our outcome is the number of diseased sites measured over four different tooth types for each subject, with subject-specific covariates available as predictors.…
Deep-SITAR uses autoencoders to predict growth patterns.
Despite significant progress made over the past twenty five years, unconstrained face verification remains a challenging problem. This paper proposes an approach that couples a deep CNN-based approach with a low-dimensional discriminative embedding learned using triplet probability constraints to solve the unconstraine…
Deep neural networks predict prostate motion from MR images.
We introduce a novel personalized Gaussian Process Experts (pGPE) model for predicting per-subject ADAS-Cog13 cognitive scores -- a significant predictor of Alzheimer's Disease (AD) in the cognitive domain -- over the future 6, 12, 18, and 24 months. We start by training a population-level model using multi-modal data …
DynForest R package predicts outcomes with time-dependent predictors.
Exploiting the wealth of imaging and non-imaging information for disease prediction tasks requires models capable of representing, at the same time, individual features as well as data associations between subjects from potentially large populations. Graphs provide a natural framework for such tasks, yet previous graph…
Profile graphical models represent multivariate dependence under varying risk factors.
Event-based models (EBM) are a class of disease progression models that can be used to estimate temporal ordering of neuropathological changes from cross-sectional data. Current EBMs only handle scalar biomarkers, such as regional volumes, as inputs. However, regional aggregates are a crude summary of the underlying hi…
Brain imaging data are important in brain sciences yet expensive to obtain, with big volume (i.e., large p) but small sample size (i.e., small n). To tackle this problem, transfer learning is a promising direction that leverages source data to improve performance on related, target data. Most transfer learning methods …
ACERL embeds networks into a low-dimensional space preserving structural and semantic properties.
Data-driven spatial filtering algorithms optimize scores such as the contrast between two conditions to extract oscillatory brain signal components. Most machine learning approaches for filter estimation, however, disregard within-trial temporal dynamics and are extremely sensitive to changes in training data and invol…
Unified HDP and LDA models for efficient topic clustering of online course queries.
Study reveals XAI methods fail in neuroimaging, suggesting domain-specific adaptation.
Objective: This paper targets a major challenge in developing practical EEG-based brain-computer interfaces (BCIs): how to cope with individual differences so that better learning performance can be obtained for a new subject, with minimum or even no subject-specific data? Methods: We propose a novel approach to align …
A new method quantifies uncertainty in brain injury simulations.
Deep learning (DL) has shown great potential in medical image enhancement problems, such as super-resolution or image synthesis. However, to date, little consideration has been given to uncertainty quantification over the output image. Here we introduce methods to characterise different components of uncertainty in suc…
Alzheimer's Disease (AD) is characterized by a cascade of biomarkers becoming abnormal, the pathophysiology of which is very complex and largely unknown. Event-based modeling (EBM) is a data-driven technique to estimate the sequence in which biomarkers for a disease become abnormal based on cross-sectional data. It can…