A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.
Paper proposes a method to enhance low-quality retinal images using optimal transport.
The paper presents algorithms for diagnosing Pathological Myopia and detecting retinal structures.
Deep convolutional neural networks (CNNs) have demonstrated impressive performance on visual object classification tasks. In addition, it is a useful model for predication of neuronal responses recorded in visual system. However, there is still no clear understanding of what CNNs learn in terms of visual neuronal circu…
OTRE uses OT to improve retinal images, outperforming existing methods.
A central challenge in neuroscience is to understand neural computations and circuit mechanisms that underlie the encoding of ethologically relevant, natural stimuli. In multilayered neural circuits, nonlinear processes such as synaptic transmission and spiking dynamics present a significant obstacle to the creation of…
An overview of the applications of deep learning in ophthalmic diagnosis using retinal fundus images is presented. We also review various retinal image datasets that can be used for deep learning purposes. Applications of deep learning for segmentation of optic disk, blood vessels and retinal layer as well as detection…
Improved retinal vessel segmentation with topology preservation trade-off.
A new method tracks retinal vessels more accurately than existing methods.
Retinal vessel segmentation is an essential step for fundus image analysis. With the recent advances of deep learning technologies, many convolutional neural networks have been applied in this field, including the successful U-Net. In this work, we firstly modify the U-Net with functional blocks aiming to pursue higher…
Model detects patterns in noisy binary data, explaining neuron activity in terms of cell assemblies.
Type 2 Diabetes (T2D) is a chronic metabolic disorder that can lead to blindness and cardiovascular disease. Information about early stage T2D might be present in retinal fundus images, but to what extent these images can be used for a screening setting is still unknown. In this study, deep neural networks were employe…
Diagnosis and treatment guidance are aided by detecting relevant biomarkers in medical images. Although supervised deep learning can perform accurate segmentation of pathological areas, it is limited by requiring a-priori definitions of these regions, large-scale annotations, and a representative patient cohort in the …
Diabetic Retinopathy is the leading cause of blindness in the world. At least 90\% of new cases can be reduced with proper treatment and monitoring of the eyes. However, scanning the entire population of patients is a difficult endeavor. Computer-aided diagnosis tools in retinal image analysis can make the process scal…
Despite significant advances in artificial intelligence (AI) for computer vision, its application in medical imaging has been limited by the burden and limits of expert-generated labels. We used images from optical coherence tomography angiography (OCTA), a relatively new imaging modality that measures perfusion of the…
Synthesizing images of the eye fundus is a challenging task that has been previously approached by formulating complex models of the anatomy of the eye. New images can then be generated by sampling a suitable parameter space. In this work, we propose a method that learns to synthesize eye fundus images directly from da…
The retinal vascular condition is a reliable biomarker of several ophthalmologic and cardiovascular diseases, so automatic vessel segmentation may be crucial to diagnose and monitor them. In this paper, we propose a novel method that combines the multiscale analysis provided by the Stationary Wavelet Transform with a m…
Neuronal circuits formed in the brain are complex with intricate connection patterns. Such complexity is also observed in the retina as a relatively simple neuronal circuit. A retinal ganglion cell receives excitatory inputs from neurons in previous layers as driving forces to fire spikes. Analytical methods are requir…
In this paper, an ensemble-based method for the screening of diabetic retinopathy (DR) is proposed. This approach is based on features extracted from the output of several retinal image processing algorithms, such as image-level (quality assessment, pre-screening, AM/FM), lesion-specific (microaneurysms, exudates) and …
Existing supervised approaches didn't make use of the low-level features which are actually effective to this task. And another deficiency is that they didn't consider the relation between pixels, which means effective features are not extracted. In this paper, we proposed a novel convolutional neural network which mak…
New data-driven Cartan connection tracks complex vascular structures.
Glaucoma is a serious ocular disorder for which the screening and diagnosis are carried out by the examination of the optic nerve head (ONH). The color fundus image (CFI) is the most common modality used for ocular screening. In CFI, the central r
Algorithm finds connected components on Lie groups for multi-orientation image analysis.
We propose UOLO, a novel framework for the simultaneous detection and segmentation of structures of interest in medical images. UOLO consists of an object segmentation module which intermediate abstract representations are processed and used as input for object detection. The resulting system is optimized simultaneousl…
Optical coherence tomography (OCT) based measurements of retinal layer thickness, such as the retinal nerve fibre layer (RNFL) and the ganglion cell with inner plexiform layer (GCIPL) are commonly used for the diagnosis and monitoring of glaucoma. Previously, machine learning techniques have utilized segmentation-based…
Diabetic eye disease is one of the fastest growing causes of preventable blindness. With the advent of anti-VEGF (vascular endothelial growth factor) therapies, it has become increasingly important to detect center-involved diabetic macular edema (ci-DME). However, center-involved diabetic macular edema is diagnosed us…
Tree-SNE combines t-SNE and hierarchical clustering for data visualization.
Effective learning of asymmetric and local features in images and other data observed on multi-dimensional grids is a challenging objective critical for a wide range of image processing applications involving biomedical and natural images. It requires methods that are sensitive to local details while fast enough to han…
Colour vision has long fascinated scientists, who have sought to understand both the physiology of the mechanics of colour vision and the psychophysics of colour perception. We consider representations of colour in anatomically constrained convolutional deep neural networks. Following ideas from neuroscience, we classi…
Federated learning framework improves model generalization and privacy.
Vision impairment due to pathological damage of the retina can largely be prevented through periodic screening using fundus color imaging. However the challenge with large scale screening is the inability to exhaustively detect fine blood vessels crucial to disease diagnosis. In this work we present a computational ima…
Deep neural network models have been proven to be very successful in image classification tasks, also for medical diagnosis, but their main concern is its lack of interpretability. They use to work as intuition machines with high statistical confidence but unable to give interpretable explanations about the reported re…
Probabilistic models can be defined by an energy function, where the probability of each state is proportional to the exponential of the state's negative energy. This paper considers a generalization of energy-based models in which the probability of a state is proportional to an arbitrary positive, strictly decreasing…
In this paper we present a novel model of the primary visual cortex (V1) based on orientation, frequency and phase selective behavior of the V1 simple cells. We start from the first level mechanisms of visual perception: receptive profiles. The model interprets V1 as a fiber bundle over the 2-dimensional retinal plane …
Convolutional neural network localizes OD and fovea in UWFoV-SLO images.
A new method for deep multiple instance learning using self-attention.
Deep learning algorithms produces state-of-the-art results for different machine learning and computer vision tasks. To perform well on a given task, these algorithms require large dataset for training. However, deep learning algorithms lack generalization and suffer from over-fitting whenever trained on small dataset,…
Local Hebbian learning is believed to be inferior in performance to end-to-end training using a backpropagation algorithm. We question this popular belief by designing a local algorithm that can learn convolutional filters at scale on large image datasets. These filters combined with patch normalization and very steep …
This article introduces a full mathematical and numerical framework for treating functional shapes (or fshapes) following the landmarks of shape spaces and shape analysis. Functional shapes can be described as signal functions supported on varying geometrical supports. Analysing variability of fshapes' ensembles requir…
Paper uses deep Q-network to correct eye movement artifacts in OCT volumes.
In this paper, we seek a clinically-relevant latent code for representing the spectrum of macular disease. Towards this end, we construct retina-VAE, a variational autoencoder-based model that accepts a patient profile vector (pVec) as input. The pVec components include clinical exam findings and demographic informatio…
Dual-edge spatial Jacobian image graph for interpretable diabetic retinopathy grading
StylEx trains a GAN to explain classifier decisions in StyleSpace.
According to the WHO, Cerebrovascular Stroke, or CS, is the second largest cause of death worldwide. Current diagnosis of CS relies on labor and cost intensive neuroimaging techniques, unsuitable for areas with inadequate access to quality medical facilities. Thus, there is a great need for an efficient diagnosis alter…
Accurate statistical models of neural spike responses can characterize the information carried by neural populations. But the limited samples of spike counts during recording usually result in model overfitting. Besides, current models assume spike counts to be Poisson-distributed, which ignores the fact that many neur…
Imaging fluorescent disease biomarkers in tissues and skin is a non-invasive method to screen for health conditions. We report an automated process that combines intraoral fluorescent porphyrin biomarker imaging, clinical examinations and machine learning for correlation of systemic health conditions with periodontal d…
Neural coding is one of the central questions in systems neuroscience for understanding how the brain processes stimulus from the environment, moreover, it is also a cornerstone for designing algorithms of brain-machine interface, where decoding incoming stimulus is highly demanded for better performance of physical de…
Deep learning has been successfully applied to a variety of image classification tasks. There has been keen interest to apply deep learning in the medical domain, particularly specialties that heavily utilize imaging, such as ophthalmology. One issue that may hinder application of deep learning to the medical domain is…
The paper introduces new structures for left-symmetric algebroids.