Paper presents a deep learning framework for classifying respiratory anomalies and lung diseases from sound recordings.
problem Classifying respiratory anomalies and lung diseases from respiratory sound recordings.
method The framework uses front-end feature extraction to transform sound into spectrograms, and a deep learning network to classify these features.
result The proposed deep learning system outperforms current state-of-the-art methods on the ICBHI benchmark dataset.
Hidden Markov Models classify cough events with high accuracy.
problem Identifying coughing events in noisy environments for health monitoring.
method Used Hidden Markov Models (HMMs) for cough classification.
result Multivariate HMMs achieved 92% AUR in classifying cough events.
Model predicts respiratory insufficiency in ALS patients with high accuracy.
problem Lack of insight into risk of error and optimal time for non-invasive ventilation.
method Combines Conformal Prediction and mixture experts to predict respiratory insufficiency and optimal time.
result Near 80% of predictions correctly identified, with confidence measures.
Deep CNN-RNN model classifies breathing sounds for respiratory disease diagnosis.
problem Automated diagnosis of respiratory diseases using wearable devices.
method Patient-specific model tuning and local log quantization of weights.
result 71.81% accuracy on leave-one-out validation with patient-specific data.
After birth, extremely preterm infants often require specialized respiratory management in the form of invasive mechanical ventilation (IMV). Protracted IMV is associated with detrimental outcomes and morbidities. Premature extubation, on the other hand, would necessitate reintubation which is risky, technically challe…
Machine learning detects and diagnoses coughs for respiratory infections.
problem Detecting and diagnosing coughs for respiratory infections.
method Convolutional Neural Networks (CNNs) to detect cough events and diagnose three illnesses.
result Accuracy over 89% for detection and diagnosis.
Lung segmentation from abnormal CXRs using data imputation.
problem Segmenting lungs from CXRs with high opacity caused by respiratory ailments.
method Modified CNN-based segmentation network with deep generative model for data imputation.
result The model can segment lungs from abnormal CXRs, extending to cases with extreme abnormalities.
DeCom predicts post-COVID RSV timing and intensity with NPI consideration.
problem Predicting RSV timing and intensity post-COVID with NPI impact.
method Deep coupled tensor factorization machine (DeCom) leveraging tensor factorization and residual modeling.
result DeCom achieves up to 46% lower RMSE and 49% lower MAE compared to baselines.
System predicts respiratory failure up to 8 hours early.
problem Early detection of respiratory failure in ICU patients.
method Machine learning on ICU patient monitoring data.
result System outperforms traditional clinical decision-making.
Develops a risk score to assist ECMO planning for critically ill patients with viral or unspecified pneumonia.
problem Lack of a risk score to guide ECMO planning for critically ill patients.
method Leverages machine learning to develop the PEER score.
result PEER score predicts mortality and decompensation in patients eligible for ECMO.
This paper automates mining of COVID-19 scholarly articles using machine learning.
problem Time-consuming and impractical manual extraction of relevant COVID-19 research articles.
method Used machine learning approaches, specifically clustering and parallel one-class support vector machines (OCSVMs), on the CORD-19 dataset.
result Parallel OCSVMs outperform other methods for both original and reduced feature space.
Model estimates lung well-aerated volume from CT images, independent of patient and imaging parameters.
problem Lack of clear connection between quantitative metrics in lung CT images and physiology.
method Patient-independent model using Gaussian fit to lower CT histogram data points.
result Model estimates well-aerated volume (WAVE) independent of CT reconstruction parameters and respiratory cycle.
AI4COVID-19 app diagnoses COVID-19 from cough samples.
problem Scalable screening tool for COVID-19 testing.
method Transfer learning and multi-pronged AI architecture.
result AI4COVID-19 can distinguish COVID-19 coughs from others.
Predictive models identify patients at risk of severe COVID-19.
problem Identifying patients at risk of severe COVID-19 to ease healthcare strain.
method Machine learning on routinely collected clinical data.
result Models predict positive SARS-CoV-2 tests, hospitalizations, and critical care with high accuracy.
R package abn fits Bayesian models to observational data.
problem Analyzing complex observational datasets with Bayesian networks.
method Bayesian and information theoretic scoring, exact and greedy search algorithms.
result Effective modeling of mixed data types and prior knowledge integration.
Paper models COVID-19 spread as spatio-temporal point processes.
problem Understanding complex spacetime propagation of COVID-19.
method Generative and intensity-free model using adversarial imitation learning.
result Imitation learning framework for scalable model inference.
Study discovers rules linking patient symptoms to unplanned ICU transfers.
problem Identifying patients at risk for unplanned ICU transfers.
method Mixed-integer optimization approach to learn association rules.
result Significant rules discovered for each patient subgroup.
Study develops algorithm to detect subtle respiratory events from PSG recordings.
problem Detecting non-apneic and non-hypopneic arousals in polysomnography recordings.
method Bidirectional LSTM classifier with 465 multi-domain features.
result 0.50 AUPRC on hidden test dataset, tied for second-best score in 2018 PhysioNet challenge.
Study repurposes open data to find potential COVID-19 drugs.
problem Developing effective treatments for COVID-19.
method Deep learning network-based approach using large scientific corpus.
result Identified 41 repurposable drugs for COVID-19.
This paper is an attempt to separate cardiac and respiratory signals from an electrical bio-impedance (EBI) dataset. For this two well-known algorithms, namely Principal Component Analysis (PCA) and Independent Component Analysis (ICA), were used to accomplish the task. The ability of the PCA and the ICA methods first …
Researchers use clustering to differentiate COVID-19 lung scans.
problem Identifying infected individuals with COVID-19.
method Applied unsupervised clustering techniques using PCA, K-Means++, and RCC.
result KM++ and RCC algorithms improved in clustering COVID-19 lung scans.
Develops a machine learning model to predict ALS progression and assistive device use.
problem Challenges in predicting clinically meaningful milestones in ALS.
method Integrates longitudinal ALSFRS-R trajectories with survival modeling.
result Generates individualized survival curves and predicts wheelchair-free survival.
The study recovers airflow from thoracic and abdominal movements using advanced signal processing.
problem Challenges in measuring airflow from thoracic and abdominal movements using small, inexpensive devices.
method Synchrosqueezing transform and locally stationary Gaussian process regression.
result Accurate prediction of airflow achieved in both normal sleep and anesthesia transition cases.
Deep learning improves CVD risk prediction from health records.
problem Predicting cardiovascular disease risk from administrative health data.
method Combined survival analysis and deep learning models.
result Deep learning models outperform traditional Cox models in accuracy and explained time-to-event occurrence.
Improved sleep apnea detection using sensor fusion and backward shortcut connections.
problem Untreated sleep apnea leads to severe health consequences; automated detection is needed.
method Late sensor fusion using backward shortcut connections to improve deep learning models.
result Significant improvement in predictive performance over single sensor methods.
Research uses SWT and BDLSTM to forecast stock and oil prices amid COVID-19.
problem Impact of COVID-19 on stock and oil prices forecasting.
method Integrates Stationary Wavelet Transform and Bidirectional Long Short-Term Memory networks.
result BDLSTM+WT-ADA achieved satisfactory results in Crude Oil price forecasting.
GRU-D detects age-specific missing patterns in vital signs.
problem Temporal missingness in clinical time series data.
method Gated recurrent unit with decay mechanisms (GRU-D) trained on MIMIC-IV vital signs.
result GRU-D achieves AUROC 0.780 and AUPRC 0.810 on bootstrapped data.
A new model combines data-driven and model-based methods for accurate air quality prediction.
problem Accurate air quality forecasts are crucial for public health.
method Combines model-based strategy and data-driven method using PTC model.
result The PTC model achieves excellent performance compared to baseline models.
AI and HPC help screen millions of molecules for SARS-CoV-2 treatments.
problem Finding effective treatments for SARS-CoV-2.
method AI and HPC enable screening of large molecule datasets.
result Data release of 23 datasets with 4.2 billion molecules.
Deep learning ensembles improve COVID-19 detection from chest X-rays.
problem Detecting COVID-19 from chest X-rays using machine learning.
method Custom CNN and ImageNet models, transfer learning, iterative pruning, ensemble learning.
result 99.01% accuracy in detecting COVID-19 from chest X-rays.
DeTraC CNN detects COVID-19 from chest X-rays with high accuracy.
problem Limited availability of annotated medical images for COVID-19 diagnosis.
method Transfer learning and class decomposition mechanism in DeTraC CNN.
result 95.12% accuracy in detecting COVID-19 from normal and severe cases.
Bayesian deep learning ensemble improves pneumonia diagnosis accuracy.
problem Manual, time-consuming pneumonia diagnosis with high inter-observer variability.
method Multi-level ensemble classification system using Bayesian Deep Learning.
result Accuracy of 98.06% in differentiating four pathologies.
DPVis integrates HMMs into visualizations for disease progression analysis.
problem Challenges in interpreting HMMs for disease progression modeling.
method Design study with clinical experts, visualizations of HMM parameters and outcomes.
result DPVis successfully evaluates and summarizes disease progression models.
This paper establishes that so-called instrumental variables enable the identification and the estimation of a fully nonparametric regression model with Berkson-type measurement error in the regressors. An estimator is proposed and proven to be consistent. Its practical performance and feasibility are investigated via …
Bayesian hypergraph inference models disease pathways from EHR data.
problem Modeling rare diseases influenced by shared risk factors.
method Bayesian hypergraph inference framework reframing multi-disease modeling.
result Interpretable disease pathways and well-calibrated uncertainty quantification.
Model learns disease self-representations for drug repositioning.
problem Drug repositioning for disease treatment.
method Enforces proximity in disease self-representations to preserve human phenome network structure.
result Method outperforms state-of-the-art approaches and produces biologically interpretable disease self-representations.
Bayesian model identifies health disparities in disease progression.
problem Health disparities bias disease progression models.
method Interpretable Bayesian model accounting for three disparities.
result Model identifies and corrects for health disparities.
Disease phenotyping algorithms process observational clinical data to identify patients with specific diseases. Supervised phenotyping methods require significant quantities of expert-labeled data, while unsupervised methods may learn non-disease phenotypes. To address these limitations, we propose the Semi-Supervised …
Bayesian meta-learning predicts Alzheimer's disease progression.
problem Predicting individual Alzheimer's disease progression from limited data.
method Bayesian meta-learning approach that dynamically predicts disease score distributions.
result Bayesian meta-learner outperforms single-task models and deterministic meta-learners, especially for long-term predictions.
VGAE learns gene-disease associations from networks, predicting disease-genes.
problem Predicting gene-disease associations from disease-gene networks.
method Introducing VGAE, a variational graph auto-encoder for disease-gene prediction.
result VGAE and C-VGAE outperform baseline methods in disease-gene prediction.
It is crucial to provide compatible treatment schemes for a disease according to various symptoms at different stages. However, most classification methods might be ineffective in accurately classifying a disease that holds the characteristics of multiple treatment stages, various symptoms, and multi-pathogenesis. More…
Elucidating the genetic basis of human diseases is a central goal of genetics and molecular biology. While traditional linkage analysis and modern high-throughput techniques often provide long lists of tens or hundreds of disease gene candidates, the identification of disease genes among the candidates remains time-con…
Alzheimer's disease (AD) is a degenerative brain disease impairing a person's ability to perform day to day activities. The clinical manifestations of Alzheimer's disease are characterized by heterogeneity in age, disease span, progression rate, impairment of memory and cognitive abilities. Due to these variabilities, …
Deep Belief Network predicts lncRNA-disease associations with high accuracy.
problem Accurately identifying lncRNA-disease associations to understand lncRNA functionality and disease mechanism.
method Proposes a DBN-based model using heterogeneous networks and DBN for feature learning.
result Obtained AUC of 0.96 and AUPR of 0.967 on standard dataset.
Enhances disease progression modeling using LLMs for complex brain connectivity.
problem Inaccurate predictions of disease spread due to oversimplified brain connectivity models.
method Uses LLMs to synthesize multi-modal relationships and learn disease trajectories from longitudinal data.
result Superior prediction accuracy and interpretability compared to traditional methods.
For many complex diseases, there is a wide variety of ways in which an individual can manifest the disease. The challenge of personalized medicine is to develop tools that can accurately predict the trajectory of an individual's disease, which can in turn enable clinicians to optimize treatments. We represent an indivi…
A method to explain disease transformation using biomarker covariance matrices.
problem Understanding disease transformation from a healthy baseline.
method Modeling healthy and disease states of biomarker covariance matrices to characterize perturbations.
result Disease perturbs the biomarker covariance structure, allowing for mechanistic explanations and individual patient prognosis.
We introduce Disease Knowledge Transfer (DKT), a novel technique for transferring biomarker information between related neurodegenerative diseases. DKT infers robust multimodal biomarker trajectories in rare neurodegenerative diseases even when only limited, unimodal data is available, by transferring information from …