New model predicts blood glucose in diabetics with improved accuracy.
problem Forecasting blood glucose in type 1 diabetics with high accuracy.
method Integrates machine learning with existing biomedical model to capture time-varying dynamics.
result Improved long-term forecasting of blood glucose up to 6 hours.
CardiacGen generates realistic ECG signals for training deep learning models.
problem Creating realistic synthetic ECG signals for training deep learning models.
method Hierarchical deep generative model with multi-objective loss functions.
result Synthetic ECG signals from CardiacGen can be used for data augmentation and improve classifier performance.
HAD-Net forecasts glucose levels with insights into insulin and carbs diffusion.
problem Inaccurate predictions in glucose level forecasting without context understanding.
method Hybrid model combining deep learning and physiological models, using recurrent attention network.
result Achieves competitive performance in glucose level forecasting with plausible diffusion insights.
New method creates indistinguishable but misclassified ECG signals.
problem Adversarial examples fool deep neural networks in ECG classification.
method Developed a technique to generate smoothed adversarial examples for single-lead ECG.
result Adversarial examples are not unique and can be collated and perturbed.
mcanalysis quantifies menstrual cycle effects in health data.
problem Lack of standardised statistical methods for menstrual cycle research.
method Fourier-basis generalised additive model (GAM) pipeline.
result Nine out of 15 health outcomes showed significant association with menstrual cycle.
SBI improves uncertainty analysis of cardiovascular biomarkers.
problem Mapping waveforms back to plausible physiological parameters.
method Simulation-based inference (SBI) for statistical inference.
result Posterior distributions provide a multi-dimensional representation of uncertainty.
Probabilistic method identifies Purkinje network from ECG data.
problem Challenging task of identifying Purkinje conduction system in heart.
method Bayesian optimization and approximate Bayesian computation for probabilistic identification.
result Generates a population of plausible Purkinje networks fitting ECG within tolerance.
This work improves the accuracy of OEF and DBV maps from qBOLD MRI data.
problem Noisy and inaccurate inference of OEF and DBV from qBOLD MRI data.
method Flexible amortized variational inference using a scaled multivariate logit-Normal distribution.
result Smooth and physiologically plausible OEF and DBV maps inferred with fewer training data.
Late fusion of clinical notes and physiological data improves ICU mortality prediction.
problem Improving ICU mortality prediction using multimodal data.
method Late fusion of clinical notes and physiological time series data with a deep learning architecture.
result Late fusion approach provides statistically significant improvement in mortality prediction performance.
Detects physiological patterns to hemodynamic stress using unsupervised deep learning.
problem Identify and characterize physiological responses to hemorrhage in raw vital sign data.
method Transform vital sign time series into latent space using unsupervised deep learning, identify clusters, and evaluate latent embeddings.
result Clusters in latent embeddings correspond to physiological response patterns matching physicians' intuition.
Model improves emotion recognition using multiple physiological signals.
problem Single physiological signal is insufficient for accurate emotion recognition.
method Fused multiple modal physiological signals (EEG, EMG, EOG) for emotion classification.
result Best classification accuracy of 94.42% on arousal and 94.02% on valence in two-class tasks.
Model explains optical illusions using geometric sub-Riemannian geodesics.
problem Understanding and explaining geometrical optical illusions.
method Neuro-mathematical model based on sub-Riemannian geodesics in the Roto-Translation Group.
result Illusory contours are described as geodesics in a new metric.
PULSE learns representations from physiological time series.
problem Lack of effective pretraining objectives for physiological time series.
method Proposes a pretraining framework exploiting dynamical systems generative model.
result PULSE learns representations that distinguish semantic classes and improve transfer learning.
Hybrid Amortized Inference improves PPG model interpretability.
problem Tension between PPG biomarker accuracy and clinical interpretability.
method Introduces PPGen for biophysical PPG signal-physiological parameter relation, and HAI for fast, robust estimation.
result Hybrid Amortized Inference accurately infers physiological parameters from PPG signals.
Adversarial transfer learning improves stress assessment across users.
problem Transfer learning challenges in physiological biosignals.
method Disentangled nuisance-robust representations using adversarial networks.
result Adversarial framework enhances cross-subjects stress assessment.
PatternLocal improves XAI for non-linear models by suppressing suppressor variables.
problem Suppressor variables cause false-positive feature attributions in non-linear models.
method PatternLocal uses locally linear surrogate models and transforms weights into a generative representation.
result PatternLocal reduces false-positive attributions and provides more reliable explanations.
PHASE predicts surgical complications from physiological signals.
problem Predicting adverse surgical outcomes from physiological signals.
method Self-supervised transfer learning for physiological signals.
result PHASE outperforms other approaches in predicting five surgical complications.
This paper addresses the problem of emotion recognition from physiological signals. Features are extracted and ranked based on their effect on classification accuracy. Different classifiers are compared. The inter-subject variability and the personalization effect are thoroughly investigated, through trial-based and su…
CLOPS improves deep learning for continuous physiological data.
problem Deep learning struggles with streaming, multi-sensor clinical data.
method CLOPS is a replay-based continual learning strategy.
result CLOPS outperforms state-of-the-art methods in continual learning scenarios.
Study classifies human stress using EEG, GSR, and PPG signals.
problem Classifying perceived human stress using physiological signals.
method Data acquisition, feature extraction (time domain), classification using multiple classifiers (SVM, Naive Bayes, MLP).
result Best classification accuracy of 75% achieved by MLP classifier.
A new model uses GPs and latent force models to predict patient responses to drugs.
problem Challenges in modeling short-term effects of drugs on patient physiology.
method Hybrid Gaussian process with latent force model for joint modeling of patient physiology and drug effects.
result The model accurately predicts patient responses to three common drugs, showing competitive performance.
Proposes a framework for extracting consistent physiological features across users.
problem Variability of biosignals across different users and tasks.
method Adversarial feature extractor for disentangled universal representations.
result Up to 8.8% improvement in average accuracy of classification.
The paper proposes a machine learning method to detect drivers' affective states using physiological signals.
problem Detecting and assessing drivers' affective states to improve driving safety and well-being.
method Multiview multi-task machine learning approach using physiological signals.
result Accounting for drive-specific differences significantly improves model performance.
UNHaP removes noise from physiological events using Hawkes processes.
problem Challenges in identifying true events from spurious ones in physiological signal analysis.
method UNHaP uses marked Hawkes processes to distinguish and unmix true events from noise.
result UNHaP significantly reduces false detection rates and enhances event understanding.
Olshausen and Field (OF) proposed that neural computations in the primary visual cortex (V1) can be partially modeled by sparse dictionary learning. By minimizing the regularized representation error they derived an online algorithm, which learns Gabor-filter receptive fields from a natural image ensemble in agreement …
PerCDL learns personalized dictionaries for physiological signals combining global and local structures.
problem Representing datasets with both global and local structures in human physiological signals.
method Personalized Convolutional Dictionary Learning (PerCDL) that combines a global and personalized local dictionary.
result PerCDL effectively learns interpretable representations for human locomotion data.
Computational analysis on physiological signals would provide immense impact for enabling automated clinical analytics. However, the class imbalance issue where negative or minority class instances are rare in number impairs the robustness of the practical solution. The key idea of our approach is intelligent augmentat…
Bayesian model detects internal bleeding in ICU patients.
problem Late detection of internal bleeding in ICU patients.
method Bayesian regime switching model analyzing vitals and labs.
result Probabilistic assessment of patient's physiological state.
We developed a new approach for the analysis of physiological time series. An iterative convolution filter is used to decompose the time series into various components. Statistics of these components are extracted as features to characterize the mechanisms underlying the time series. Motivated by the studies that show …
Hybrid machine learning improves gallstone risk prediction.
problem Complex gallstone disease risk factors and interactions.
method Adaptive LASSO for variable selection, BART for interactions, differential equations for interpretation.
result Enhanced prediction accuracy and actionable insights.
The relation between performance and stress is described by the Yerkes-Dodson Law but varies significantly between individuals. This paper describes a method for determining the individual optimal performance as a function of physiological signals. The method is based on attention and reasoning tests of increasing comp…
Generative model improves TMP reconstruction from ECG data.
problem Reconstructing cardiac transmembrane potential from surface ECG data is an ill-posed inverse problem.
method A novel model-constrained inference framework using a variational auto-encoder (VAE) with LSTM networks to learn the conditional likelihood of TMP and the prior distribution of generative factors.
result The method significantly improves TMP reconstruction accuracy compared to conventional methods.
Motivation: Cell-biological processes are regulated through a complex network of interactions between genes and their products. The processes, their activating conditions, and the associated transcriptional responses are often unknown. Organism-wide modeling of network activation can reveal unique and shared mechanisms…
Algorithm selects optimal segment for physiological signal analysis.
problem Physiological signals are often corrupted by noise, requiring selective analysis.
method Combines deep neural networks for signal analysis and combinatorial optimization for segment selection.
result Significant improvement in system performance, e.g. 2.4% increase in sensitivity for heart sound segmentation.
UniPhyNet improves cognitive load classification accuracy using EEG, ECG, and EDA signals.
problem Classifying cognitive load using multimodal physiological data.
method Unified network architecture integrating multiscale parallel convolutional blocks, ResNet-type blocks, and channel block attention module. Uses bidirectional gated recurrent unit for temporal dependencies.
result Improves raw signal classification accuracy from 70% to 80% (binary) and 62% to 74% (ternary) on CL-Drive dataset.
This paper investigates the use of distributed processing on the problem of emotion recognition from physiological sensors using a popular machine learning library on distributed mode. Specifically, we run a random forests classifier on the biosignal-data, which have been pre-processed to form exclusive groups in an un…
ARFs generate plausible counterfactuals for models, improving model understanding.
problem Creating realistic counterfactuals for model analysis.
method Adversarial Random Forests (ARFs) for generating plausible counterfactuals.
result ARFs efficiently generate plausible counterfactuals in a model-agnostic way.
PhysioMTL learns personalized HRV rhythms from wearable data, improving prediction and counterfactual analysis.
problem Challenges in interpreting HRV measurements due to variability and stressors.
method PhysioMTL combines Optimal Transport and MTL to learn personalized diurnal rhythms from heterogeneous data.
result PhysioMTL outperforms other methods in predicting unseen subjects and generating counterfactual effects.
`Biologically inspired' activation functions, such as the logistic sigmoid, have been instrumental in the historical advancement of machine learning. However in the field of deep learning, they have been largely displaced by rectified linear units (ReLU) or similar functions, such as its exponential linear unit (ELU) v…
Study explores DNNs' reliance on existing vs. new features in physiological signals.
problem Understanding how deep neural networks discover new features in physiological signals.
method Proposes a method to remove hand-engineered features and force DNNs to learn new representations.
result DNNs often rediscover known features, but can also learn new ones.
Characterizing the dynamic interactive patterns of complex systems helps gain in-depth understanding of how components interrelate with each other while performing certain functions as a whole. In this study, we present a novel multimodal data fusion approach to construct a complex network, which models the interaction…
Functional brain networks exhibit dynamics on the sub-second temporal scale and are often assumed to embody the physiological substrate of cognitive processes. Here we analyse the temporal and spatial dynamics of these states, as measured by EEG, with a hidden Markov model and compare this approach to classical EEG mic…
We define and compute plausible counterfactual explanations using density constraints.
problem Efficiently compute plausible counterfactual explanations for machine learning models.
method Propose and study a formal definition of plausible counterfactual explanations, use density estimators, and introduce convex density constraints.
result Convex density constraints ensure plausible and feasible counterfactual explanations.
New method generates plausible counterfactuals for time series classification.
problem Generating realistic counterfactuals for time series data.
method Gradient-based optimization with soft-DTW alignment and multi-faceted loss function.
result Our method outperforms existing approaches in temporal realism and distributional alignment.
OFVF uses Bayesian plausibility sets for robust exploration in reinforcement learning.
problem Exploration in reinforcement learning, especially in poorly understood states and actions.
method Bayesian approach with plausibility sets constructed based on sensible value functions.
result OFVF constructs tighter optimistic estimates for exploration, leading to robust policies.
Paper identifies resting positions using EGG, ECG, respiration rate, and SpO2.
problem Identifying the resting position for health monitoring.
method Hybrid stacked ensemble machine learning model combining Decision tree, Random Forest, and Xgboost.
result 100% accurate prediction of resting positions.
A neuron is a basic physiological and computational unit of the brain. While much is known about the physiological properties of a neuron, its computational role is poorly understood. Here we propose to view a neuron as a signal processing device that represents the incoming streaming data matrix as a sparse vector of …
Personalized stress model using transfer learning from 20 participants.
problem Limited generalizability of machine learning models due to individual physiological differences.
method Transfer learning from a base model trained on 20 participants' physiological data collected in real-time.
result Improved model personalization and cross-domain performance.