Deep learning detects Crohn's disease in MRI images.
problem Detecting Crohn's disease in MRI images.
method Residual Networks for feature extraction and soft attention mechanisms for interpretability.
result Deep learning algorithms perform comparably to clinical standards with faster inference.
This study assesses the reproducibility of 1H-MRS scans across different vendors and sessions.
problem Lack of harmonization in magnetic resonance spectroscopy protocols among vendors.
method Analysis of CV and ICC for within- and between-sessions, and correlation coefficients for across machines.
result Metabolite concentrations are highly reproducible across different vendors and sessions.
This work uses Sylvester normalizing flows for more accurate metabolite quantification in MRS.
problem Challenges in accurate metabolite quantification in MRS due to spectral overlap, low SNR, and artifacts.
method Bayesian inference framework with physics-informed Sylvester normalizing flows.
result Accurate metabolite quantification, well-calibrated uncertainties, and insights into parameter correlations and multi-modal distributions.
New Bayesian method for joint sparse parameter inference.
problem Inference of jointly sparse parameter vectors from multiple measurements.
method Hierarchical Bayesian learning with joint sparsity-promoting priors.
result New algorithms consistently outperform existing methods in numerical experiments.
New technique halves scan time for multi-echo MR images.
problem Slow acquisition of multi-echo magnetic resonance images.
method Structured deep dictionary learning for adaptive reconstruction.
result Scan time reduced by half compared to state-of-the-art.
Due to the rapid innovation of technology and the desire to find and employ biomarkers for neurodegenerative disease, high-dimensional data classification problems are routinely encountered in neuroimaging studies. To avoid over-fitting and to explore relationships between disease and potential biomarkers, feature lear…
Normal forms prove dynamical results for magnetic fields on surfaces.
problem Existence and rigidity of Zoll flows on surfaces.
method Proved normal forms for strong magnetic fields and used them to derive dynamical results.
result Flow cannot be Zoll unless specific conditions hold.
CycleQSM uses deep learning to accurately map tissue magnetic susceptibility without needing paired data.
problem Accurately mapping magnetic susceptibility values from phase images using QSM.
method Unsupervised deep learning approach using physics-informed cycleGAN.
result The method provides more accurate QSM maps compared to existing deep learning approaches.
SrvfNet aligns multiple functional data to templates without supervision.
problem Aligning large collections of functional data to templates without labeled data.
method Generative deep learning framework using SRVF and fully-connected layers.
result Framework achieves alignment and optimal template prediction without supervision.
Independent component analysis (ICA), as an approach to the blind source-separation (BSS) problem, has become the de-facto standard in many medical imaging settings. Despite successes and a large ongoing research effort, the limitation of ICA to square linear transformations have not been overcome, so that general INFO…
Obtaining magnetic resonance images (MRI) with high resolution and generating quantitative image-based biomarkers for assessing tissue biochemistry is crucial in clinical and research applications. How- ever, acquiring quantitative biomarkers requires high signal-to-noise ratio (SNR), which is at odds with high-resolut…
Current popular methods for Magnetic Resonance Fingerprint (MRF) recovery are bottlenecked by the heavy storage and computation requirements of a dictionary-matching (DM) step due to the growing size and complexity of the fingerprint dictionaries in multi-parametric quantitative MRI applications. In this paper we study…
Many problems of low-level computer vision and image processing, such as denoising, deconvolution, tomographic reconstruction or super-resolution, can be addressed by maximizing the posterior distribution of a sparse linear model (SLM). We show how higher-order Bayesian decision-making problems, such as optimizing imag…
Study confirms sparse coding in whole brain using MRI data.
problem Sparse coding in the whole brain's neural activities.
method Applied various matrix factorization methods to fMRI data.
result Sparse coding hypothesis in information representation in the whole human brain is confirmed.
Stochastic VB improves nonlinear model inference speed and accuracy.
problem Bayesian inference of nonlinear models from noisy data.
method Stochastic Variational Bayesian (VB) inference for nonlinear models.
result Stochastic VB achieves comparable parameter recovery to analytical solution but is faster.
PS-VAE extracts multi-parameter MRI biomarkers with uncertainty quantification.
problem Uncertainty in inverse problems limits clinical acceptance of quantitative MRI methods.
method Physics-Structured Variational Autoencoder (PS-VAE) integrating physics simulator and self-supervised learning.
result PS-VAE provides full covariance of inter-parameter correlations and accelerates multi-parametric MRI quantification.
ANNs extrapolate without training data, leading to uncertain predictions.
problem Uncertainty in ANN predictions for unseen data.
method Quantitative approach based on long-standing methods.
result Quantitative uncertainty assessment for ANN predictions.
Develops statistical guarantees for image-to-image regression models.
problem Current image-to-image regression models lack statistical guarantees for model mistakes and hallucinations.
method Uncertainty quantification techniques with rigorous statistical guarantees for image-to-image regression problems.
result Derives uncertainty intervals around each pixel with formal mathematical guarantees.
Neural network improves aneurysm classification accuracy in MRI images.
problem Classifying aneurysm status in MRI images with varying radiologist expertise.
method Constructed neural network trained on radiologists' annotations, compared to a control model.
result Proposed model had a higher area under the curve (0.845 vs. 0.793).
A new method learns high-frequency components for better image reconstruction.
problem Efficiently reconstructing feature details in under-sampled imaging.
method Proposes HF-DAEP, a denoising autoencoder using multi-profile high-frequency components.
result Demonstrates improved reconstruction of feature details in MRI and CT.
Bayesian PixelCNN improves semi-supervised learning in MRI data.
problem Lack of robust uncertainty measures in deep generative models for MRI data.
method Extended PixelCNN to volumetric MRI data and reformulated as a deep Gaussian process.
result Improved semi-supervised learning performance in MRI data.
Extracting information from functional magnetic resonance (fMRI) images has been a major area of research for more than two decades. The goal of this work is to present a new method for the analysis of fMRI data sets, that is capable to incorporate a priori available information, via an efficient optimization framework…
Dimensional reduction of high dimensional data can be achieved by keeping only the relevant eigenmodes after principal component analysis. However, differentiating relevant eigenmodes from the random noise eigenmodes is problematic. A new method based on the random matrix theory and a statistical goodness-of-fit test i…
Proposes a deep neural network approach for image response regression.
problem Associations between medical images and covariates.
method Spatially varying coefficient models with deep neural networks.
result Explicitly accounts for spatial smoothness and subject heterogeneity.
SFCNeXt estimates brain age from small MRI datasets.
problem Efficiently estimating brain age from limited MRI data.
method Simple fully convolutional network (SFCNeXt) with SPEC and HRL.
result SFCNeXt outperforms complex models in small sample size scenarios.
Deep learning improves brain tumor detection with few data.
problem Scarce training data and data corruption in medical diagnosis.
method Data distillation and augmentation to improve deep neural network training.
result Reaches human expert-level accuracy with just a few thousand training examples.
QC methods improve reliability of machine learning-based image segmentation.
problem Inaccuracies in machine learning algorithms limit their clinical applicability.
method Analysis and validation of QC approaches for automatic segmentation.
result Aggregation of uncertainty and Dice prediction methods improved segmentation reliability.
Magnetic resonance imaging (MRI) is widely used in clinical practice, but it has been traditionally limited by its slow data acquisition. Recent advances in compressed sensing (CS) techniques for MRI reduce acquisition time while maintaining high image quality. Whereas classical CS assumes the images are sparse in know…
We propose a novel automatic method for accurate segmentation of the prostate in T2-weighted magnetic resonance imaging (MRI). Our method is based on convolutional neural networks (CNNs). Because of the large variability in the shape, size, and appearance of the prostate and the scarcity of annotated training data, we …
Automated labeling of intracranial arteries improves accuracy and efficiency.
problem Challenges in accurately labeling intracranial arteries due to variations and limited datasets.
method Graph Neural Network (GNN) combined with hierarchical refinement for improved accuracy.
result Achieved 97.5% node labeling accuracy on a testing set of 105 scans.
Proposes a method to improve skull stripping accuracy in MRI images.
problem Skull stripping accuracy in MRI images is improved.
method Context-encoding method to empower 2D networks with 3D semantic information.
result Achieves superior accuracy (dice score 99.6% on NFBS, 99.09% on LPBA40, 99.17% on OASIS) compared to state-of-the-art methods.
Deep learning method improves myelin water fraction estimation.
problem Estimating myelin water fraction in the brain using magnetic resonance relaxometry.
method Combines input layer regularization with automated regularization hyperparameter tuning.
result Proposed method outperforms classical methods and multi-layer perceptrons on in vivo brain data.
Here, we present a novel approach to solve the problem of reconstructing perceived stimuli from brain responses by combining probabilistic inference with deep learning. Our approach first inverts the linear transformation from latent features to brain responses with maximum a posteriori estimation and then inverts the …
Decreasing magnetic resonance (MR) image acquisition times can potentially reduce procedural cost and make MR examinations more accessible. Compressed sensing (CS)-based image reconstruction methods, for example, decrease MR acquisition time by reconstructing high-quality images from data that were originally sampled a…
Deep learning improves automated detection of epileptic seizures.
problem Automated detection of epileptic seizures using traditional methods is limited.
method Deep learning techniques for feature extraction and classification.
result Deep learning enhances accuracy in diagnosing epileptic seizures.
Method synthesizes 4D CMR images from XCAT model using GAN and SPADE.
problem Synthesizing realistic 4D CMR images with annotations and adaptable styles.
method Hybrid GAN approach with XCAT anatomical ground truth and SPADE for semantic preservation.
result Synthesized images with modality-specific features learned from real CMR data.
NAS improves gliomas segmentation on MRI scans.
problem Designing optimal deep learning architectures for brain tumor segmentation.
method Neural architecture search with probabilistic parameter learning for MRI brain tumor segmentation.
result Two optimal neural architectures for brain tumor segmentation were discovered.
Nuclear magnetic resonance (NMR) spectroscopy exploits the magnetic properties of atomic nuclei to discover the structure, reaction state and chemical environment of molecules. We propose a probabilistic generative model and inference procedures for NMR spectroscopy. Specifically, we use a weighted sum of trigonometric…
Improved fMRI activation detection for single-subject studies.
problem Challenges in detecting activation in low-signal fMRI studies.
method Model-based approach using MixfMRI R package.
result Reliable activation detection in single-subject fMRI studies.
Paper develops a classification method using matrix-variate t-distributions.
problem Classifying matrix-valued observations with dependence structure.
method Develops an Expectation-Maximization algorithm for discriminant analysis.
result Method shows promise on various datasets.
Study identifies five AD subtypes using graph diffusion and similarity learning.
problem Identifying homogeneous AD subtypes to improve diagnosis and treatment.
method Unsupervised clustering with graph diffusion and similarity learning.
result Five distinct AD subtypes identified with significant differences in biomarkers and clinical features.
Study uses deep learning to quickly estimate tissue properties for personalized radio-frequency dosimetry.
problem Time-consuming tissue segmentation limits personalized radio-frequency dosimetry.
method Developed a learning-based approach using Convolutional Neural Networks (CNN) for magnetic resonance images.
result Smooth distribution of dielectric properties improves SAR distribution consistency.
Traditionally, nonlinear inversion, direct inversion, or wave estimation methods have been used for reconstructing images from MRE displacement data. In this work, we propose a convolutional neural network architecture that can map MRE displacement data directly into elastograms, circumventing the costly and computatio…
Study compares data-driven vs model-based MRS quantification strategies, focusing on resilience to out-of-distribution effects.
problem Resilience to out-of-distribution effects in data-driven MRS quantification.
method Compared three data-driven strategies (supervised regression, self-supervised learning, test-time adaptation) against model-based fitting tools.
result Test-time adaptation proved most resilient to out-of-distribution effects, while self-supervised learning achieved intermediate performance.
Dual U-net models improve multi-channel MRI image reconstruction.
problem Improving MRI image reconstruction from multi-channel data.
method Two-element U-nets (W-nets) in k-space and image domains, evaluated for four configurations.
result Dual domain methods are more advantageous for simultaneous reconstruction of all channels.
Purpose: Arterial Spin Labeling (ASL) is a quantitative, non-invasive alternative to perfusion imaging with contrast agents. Fixing values of certain model parameters in traditional ASL, which actually vary from region to region, may introduce bias in perfusion estimates. Adopting Magnetic Resonance Fingerprinting (MRF…
Generative Adversarial Networks create realistic brain MRI images.
problem Lack of sufficient training data for medical research.
method Experimented three GAN architectures with different loss functions and hyperparameter tuning.
result Achieved high-quality, realistic synthetic MRIs with gradient penalty and mini-batch similarity layer.
Graph neural networks predict solid-state NMR parameters from atomic structures.
problem Efficiently predicting NMR parameters from atomic structures for complex materials.
method Graph neural networks applied to tensor quantities for anisotropic magnetic shielding and electric field gradient.
result Improved accuracy in predicting NMR properties from diverse and complex materials.