Functional MRI (fMRI) and diffusion MRI (dMRI) are non-invasive imaging modalities that allow in-vivo analysis of a patient's brain network (known as a connectome). Use of these technologies has enabled faster and better diagnoses and treatments of neurological disorders and a deeper understanding of the human brain. R…
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48 results for “MRI connectome”
Efficiently clusters nodes in Gaussian graphical models from data.
problem Clustering nodes in Gaussian graphical models directly from data.
method Clusters nodes based on the similarity of their network neighborhoods defined by partial correlations. Uses matrix factors for limited data.
result Demonstrates improved clustering of nodes in Gaussian graphical models.
Two embedding methods in spectral graph clustering yield different but valid groupings.
problem Clustering vertices of a graph without true groupings.
method Spectral graph clustering using Laplacian or Adjacency spectral embedding.
result Laplacian embedding captures left hemisphere/right hemisphere structure, while adjacency embedding captures gray matter/white matter structure.
BrainSurfCNN predicts task contrasts from resting-state fingerprints, improving accuracy over baseline.
problem Predicting task-evoked activity from resting-state functional connectivity.
method Surface-based convolutional neural network (BrainSurfCNN) with reconstructive-contrastive loss.
result Significantly improved accuracy in predicting task contrasts over baseline.
There has been an explosion of interest in functional Magnetic Resonance Imaging (MRI) during the past two decades. Naturally, this has been accompanied by many major advances in the understanding of the human connectome. These advances have served to pose novel challenges as well as open new avenues for research. One …
Framework integrates brain connectivity data for clinical predictions.
problem Predicting clinical outcomes from brain connectivity data.
method Structurally-regularized Dynamic Dictionary Learning (sr-DDL) and LSTM-ANN block.
result Framework outperforms state-of-the-art approaches in clinical outcome prediction.
Ensemble learning improves rs-fMRI predictions using 3D CNNs.
problem Improving specificity and sensitivity of rs-fMRI measurements through better parcellation schemes.
method Ensemble learning with 3D CNNs to combine predictions from different parcellations.
result Ensemble learning with 3D CNNs outperforms traditional methods in rs-fMRI classification and regression tasks.
Unified model combines neural networks and dictionary learning for clinical predictions from brain data.
problem Predicting clinical severity from brain imaging data.
method Combines neural networks with dictionary learning to model patient-specific and shared features.
result Unified model outperforms state-of-the-art methods in predicting clinical severity.
The paper characterizes brain states and transitions using functional MRI data.
problem Characterizing the dynamic reconfiguration of neural systems in brain states.
method Bayesian model-based characterization of latent brain states and posterior predictive discrepancy using the latent block model.
result The model detects transitions between latent brain states and identifies distinctive community patterns in task-fMRI data.
Synthetic learning improves neonatal brain MRI segmentation robustness.
problem Challenges in neonatal brain MRI segmentation due to image contrast and anatomical variations.
method Synthetic learning model trained on few T2-weighted volumes, then enhanced with motion artifacts and over-segmentation.
result Synthetic learning robust to image contrast and improves segmentation of both T1- and T2-weighted images.
Paper detects abnormalities in brain activity patterns using unsupervised learning.
problem Detecting abnormalities in resting-state brain activity patterns.
method Two strategies: autoencoder approach and next frame prediction.
result Both approaches can learn useful representations of rs-fMRI data for abnormality detection.
Resting-state functional MRI (rs-fMRI) scans hold the potential to serve as a diagnostic or prognostic tool for a wide variety of conditions, such as autism, Alzheimer's disease, and stroke. While a growing number of studies have demonstrated the promise of machine learning algorithms for rs-fMRI based clinical or beha…
We present semiparametric spectral modeling of the complete larval Drosophila mushroom body connectome. Motivated by a thorough exploratory data analysis of the network via Gaussian mixture modeling (GMM) in the adjacency spectral embedding (ASE) representation space, we introduce the latent structure model (LSM) for n…
Stochastic encoding improves gender classification of brain networks from UK Biobank data.
problem Complexity and bias in interpreting deep learning models of brain connectivity.
method Stochastic encoding in ensemble of CNNs, multivariate balancing algorithm.
result AUROC of 0.8459, with resting-state data more accurate than task data.
Deep transfer learning improves fMRI decoding from small datasets.
problem Small sample size and high dimensionality of fMRI datasets.
method Transfer learning using a pre-trained deep learning model on a large dataset.
result A pre-trained DL model outperforms a model trained from scratch on a new dataset.
In this work, we propose a simple yet effective solution to the problem of connectome inference in calcium imaging data. The proposed algorithm consists of two steps. First, processing the raw signals to detect neural peak activities. Second, inferring the degree of association between neurons from partial correlation …
Large bundles of myelinated axons, called white matter, anatomically connect disparate brain regions together and compose the structural core of the human connectome. We recently proposed a method of measuring the local integrity along the length of each white matter fascicle, termed the local connectome. If communicat…
We propose a novel denoising framework for task functional Magnetic Resonance Imaging (tfMRI) data to delineate the high-resolution spatial pattern of the brain functional connectivity via dictionary learning and sparse coding (DLSC). In order to address the limitations of the unsupervised DLSC-based fMRI studies, we u…
DCNs mimic neuronal networks for improved neural classification.
problem Lack of topological similarity between DNNs and biological neural networks.
method Developed DCNs with topologies inspired by real-world neuronal networks.
result High classification accuracy achieved by DCNs.
Auto-encoding brain networks with applications to analyzing large-scale brain imaging datasetsstat.ML
Develops a new method to analyze brain networks for cognitive traits.
problem Challenges in summarizing and relating brain connectomes to human traits.
method Graph Auto-Encoding (GATE) model using deep learning.
result GATE improves prediction accuracy and efficiency over existing methods.
Biological and social systems consist of myriad interacting units. The interactions can be represented in the form of a graph or network. Measurements of these graphs can reveal the underlying structure of these interactions, which provides insight into the systems that generated the graphs. Moreover, in applications s…
Neural connectomics has begun producing massive amounts of data, necessitating new analysis methods to discover the biological and computational structure. It has long been assumed that discovering neuron types and their relation to microcircuitry is crucial to understanding neural function. Here we developed a nonpara…
In statistical connectomics, the quantitative study of brain networks, estimating the mean of a population of graphs based on a sample is a core problem. Often, this problem is especially difficult because the sample or cohort size is relatively small, sometimes even a single subject. While using the element-wise sampl…
This paper considers the problem of brain disease classification based on connectome data. A connectome is a network representation of a human brain. The typical connectome classification problem is very challenging because of the small sample size and high dimensionality of the data. We propose to use simultaneous app…
New brain atlas method improves classification accuracy.
problem Creating accurate brain atlases from connectomes.
method Connectivity-based hierarchical clustering and consensus aggregation.
result Consensus parcellation outperforms existing atlases in classification tasks.
Machine learning techniques have become increasingly popular in the field of resting state fMRI (functional magnetic resonance imaging) network based classification. However, the application of convolutional networks has been proposed only very recently and has remained largely unexplored. In this paper we describe a c…
Unsupervised framework captures acquisition variability in structural connectomes.
problem Acquisition differences across sites, scanners, and protocols complicate structural connectome analysis.
method An unsupervised framework using architectural annealing to balance discrete and continuous latent variables.
result Architectural annealing produces stronger site learning than baseline models.
Substantial evidence indicates that major psychiatric disorders are associated with distributed neural dysconnectivity, leading to strong interest in using neuroimaging methods to accurately predict disorder status. In this work, we are specifically interested in a multivariate approach that uses features derived from …
Financial markets modeled like brain networks using dMNC.
problem Understanding latent dynamics in financial markets.
method Biologically inspired framework using dMNC.
result Structural persistence, regime shifts, and early warning signals identified.
Deep learning classifies autism vs controls with high accuracy using large fMRI dataset.
problem Classification difficulty of autism vs typically developing controls with fMRI data.
method Ensemble CNN model trained on 43,858 fMRI datapoints, employing class-balancing and visualization methods.
result Deep learning models achieve AUROCs of 0.6774, 0.7680, and 0.9222 for ASD vs TD, gender, and task vs rest classifications.
New network learns non-parametric invariances from data.
problem Modeling non-parametric invariances in data.
method Introduces PRC-NPTN networks with permanent random connectomes.
result Improves generalization and outperforms existing methods.
Study predicts gender from brain FC at multiple scales using deep learning and Bayesian methods.
problem Predicting gender from brain functional connectivity.
method Deep learning and Bayesian deep learning applied to brain FC data from 1003 healthy adults.
result Bayesian deep learning provides accurate predictions and uncertainty information.
R-PLS improves analysis of brain functional connectivity matrices.
problem Improving analysis of functional connectivity matrices in brain imaging.
method Introducing R-PLS, a generalization of PLS for symmetric positive definite matrices.
result R-PLS identifies key functional connections in brain imaging datasets.
New methods improve brain data analysis from fMRI datasets.
problem Simplified brain models from correlational values are insufficient.
method Deep learning and geometric deep learning techniques.
result Improved predictive spatio-temporal brain data representation.
Researchers compare brain connectomes using geodesic distance on manifold for twin pairs.
problem Assessing functional similarity in brain networks between monozygotic and dizygotic twins.
method Using fMRI data, the researchers compared functional networks between mono- and dizygotic twin pairs by measuring similarity with geodesic distance on graph Laplacians.
result Functional networks are more similar in monozygotic twins compared to dizygotic twins, and similarity is higher for task-relevant networks.
Generative model predicts multiple brain graphs from one, preserving topology.
problem Predicting multiple brain graphs from a single one, preserving topology.
method MultiGraphGAN architecture, graph adversarial auto-encoder, cluster-specific decoders, topological loss.
result Significantly outperformed variants in multi-view brain graph generation.
Python package for SPD matrix distances, reproducible and extensible.
problem Computing distances between SPD matrices for various applications.
method Unified, extensible framework supporting multiple SPD metrics.
result Reproducible and accessible SPD matrix comparison tool.
Learning Weighted Submanifolds with Variational Autoencoders and Riemannian Variational Autoencodersstat.ML
This paper develops a method to learn lower-dimensional submanifolds of brain connectomes.
problem Learning lower-dimensional representations of manifold-valued data, especially brain connectomes.
method Riemannian variational autoencoder with intrinsic generative model.
result The method can learn weighted submanifolds of manifold-valued data.
XPDNet wins MRI reconstruction challenge with neural network.
problem MRI reconstruction from under-sampled data.
method Inspired by MRI and computer vision best practices, XPDNet uses a neural network.
result XPDNet achieved state-of-the-art results in the 2020 fastMRI challenge.
Generative adversarial networks reconstruct MRI images without full data.
problem Lack of fully-sampled ground truth data for supervised MRI reconstruction.
method Generative adversarial networks for unsupervised MRI reconstruction.
result Reconstructed images show more anatomical structure than conventional methods.
3D CNN accurately classifies infant neurodevelopmental age from MRI scans.
problem Estimating neurodevelopmental age in infants from MRI data.
method 3D Convolutional Neural Network (3D CNN) trained on MRI images of 112 infants.
result 3D CNN achieves 99% sensitivity and 98.3% specificity in age classification.
fastMRI dataset helps machine learning for MRI faster, cheaper.
problem Accelerating MRI to reduce costs and patient stress.
method Open dataset and benchmarks for machine learning.
result Machine learning can reconstruct MRI images from fewer data.
Radiomics approach improves cardiac CVD diagnosis from cine-MRI.
problem Inaccurate expert visualization or clinical indices for CVD classification.
method Estimating radiomic features from cine-MRI, feature selection, advanced machine learning.
result Radiomics features correctly classified 100 cases of five cardiac classes.
MRI Parameter Mapping via Gaussian Mixture VAE: Breaking the Assumption of Independent Pixelseess.IV
New MRI method maps tissue parameters more accurately by ignoring voxel independence.
problem Voxel independence assumption limits model fitting reliability and repeatability.
method Self-supervised deep variational approach with Gaussian mixture prior.
result Our method outperforms current techniques in dMRI simulations and real data.
StaPLR improves Alzheimer's disease classification by identifying important MRI scan types and measures.
problem Classifying Alzheimer's disease using multi-source MRI data.
method Stacked penalized logistic regression (StaPLR) with hierarchical multi-view structure and new view importance measure.
result StaPLR identifies the most important MRI scan types and measures for Alzheimer's disease classification.
Deep CNN classifies EEG-based brain connectivity in schizophrenia.
problem Classifying neuropsychiatric disorders using EEG connectivity.
method Multi-domain connectome CNN framework integrating time and frequency-domain metrics.
result MDC-CNN achieves accuracy in schizophrenia classification.
Paper improves reproducibility of AD classification using diffusion MRI.
problem Difficulty in comparing and reproducing classification performance of AD studies using diffusion MRI.
method Extended a framework to ADNI data, including preprocessing and feature extraction. Used non-nested validation and compared different components.
result Diffusion MRI features can achieve comparable performance to T1w MRI, with proper feature selection and validation methods.
LOUPE optimizes MRI under-sampling patterns for faster scans.
problem Accelerating MRI scans while maintaining image quality.
method End-to-end learning framework that trains on full-resolution scans.
result LOUPE-optimized masks yield superior reconstructions with 8x faster scans.