Background: Many authors have described MELD as a predictor of short-term mortality in the liver transplantation waiting list. However MELD score accuracy to predict long term mortality has not been statistically evaluated. Objective: The aim of this study is to analyze the MELD score as well as other variables as a pr…
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48 results for “Liver Transplant”
Liver transplant patients have a 25% chance of developing diabetes within 5 years.
problem Predicting new onset diabetes after liver transplant to improve patient care.
method Comparison of time-to-event prediction models and classifiers, including regularized Cox proportional-hazards model.
result Regularized Cox proportional-hazards model achieved high Concordance Index of 0.863.
Local discovery method uncovers direct unfairness in complex systems.
problem Identifying causal pathways of unfairness in complex domains.
method Local discovery for direct discrimination (LD3) method.
result LD3 returns a valid adjustment set (VAS) for assessing unfairness.
Method learns evolving policies in healthcare contexts.
problem Understanding non-stationary behavior in evolving decision-making processes.
method Inverse Contextual Bandits (ICB) approach for learning interpretable representations of non-stationary behavior.
result Demonstrated applicability and accuracy of ICB method in liver transplantation policies.
Paper develops a model to predict kidney transplant success.
problem Mismatched deceased donor-recipient kidney leads to post-transplant death.
method Data analysis of 584 imported kidneys from 12 transplant centers.
result Predicting model reduces mortality rate due to kidney mismatch.
Machine learning improves kidney transplant outcomes prediction.
problem Improving prediction of kidney transplant success.
method Random forest machine learning model trained on kidney donor risk index data.
result Random forest predicted 2,148 more successful transplants than the risk index.
Paper learns data-driven organ matching rules from observational data.
problem Tackles organ transplantation compatibility using observational data.
method Representation learning to cluster donors and apply recipient transformations.
result Model outperforms human experts in predicting transplant outcomes.
New method transplants specific neural networks to generic ones without training samples.
problem Learning massive tasks and categories requires collecting samples for all at once.
method Designs a functionally interpretable generic network and uses back-distillation for transplanting.
result Method without training samples outperforms with 100 samples.
Conway's drum quiltsmath.GT
John Conway created pairs of domains that sound the same for a special kind of music.
problem Creating domains that sound the same for a special kind of music.
method Using his theory of quilts, Conway developed pairs of glueing diagrams.
result Conway's pairs of domains are isospectral for the Laplace operator.
We study isospectrality for manifolds with mixed Dirichlet-Neumann boundary conditions and express the well-known transplantation method in graph- and representation-theoretic terms. This leads to a characterization of transplantability in terms of monomial relations in finite groups and allows for the generating of ne…
This paper focuses on a new task, i.e., transplanting a category-and-task-specific neural network to a generic, modular network without strong supervision. We design an functionally interpretable structure for the generic network. Like building LEGO blocks, we teach the generic network a new category by directly transp…
We say that a germ G of a geometric structure can be transplanted into a manifold M if there is a suitable geometric structure on M which agrees with G on a neighborhood of some point P of M. We show for a wide variety of geometric structures that this transplantation is always possible provided that M does in fact adm…
A clinically motivated self-supervised approach for content-based image retrieval of CT liver imagescs.CV
Self-supervised method improves CBIR of CT liver images.
problem Limited labeled data and lack of transparency in deep CBIR systems.
method Proposes a self-supervised learning framework with domain-knowledge integration.
result Improved performance and generalization across datasets.
Proposes a neural network for dynamic risk prediction of AMD using longitudinal fundus images.
problem Dynamic risk prediction for progressive eye disorders like AMD.
method tdCoxSNN, a time-dependent Cox survival neural network integrating CNN.
result Demonstrates commendable predictive performance in AMD and PBC datasets.
Paper proposes abstention in machine learning for better liver disease diagnosis accuracy.
problem Improving accuracy in automated liver disease diagnosis using ultrasound images.
method Implemented a machine learning model with abstention capability, using stochastic gradient solver.
result The proposed abstention model outperforms existing models in liver disease classification.
Data mining techniques on the biological analysis are spreading for most of the areas including the health care and medical information. We have applied the data mining techniques, such as KNN, SVM, MLP or decision trees over a unique dataset, which is collected from 16,380 analysis results for a year. Furthermore we h…
Novel fusion network combines polarization and radiomics features for liver cancer classification.
problem Challenges in histopathological diagnosis of HCC and ICC.
method Two-tier fusion approach: feature-level and classification-level.
result Significantly enhances classification accuracy, even at reduced resolutions.
Deep learning methods, and in particular convolutional neural networks (CNNs), have led to an enormous breakthrough in a wide range of computer vision tasks, primarily by using large-scale annotated datasets. However, obtaining such datasets in the medical domain remains a challenge. In this paper, we present methods f…
Omics-GAN uses GANs to generate synthetic multi-omics data for improved disease prediction.
problem Limited sample sizes, noise, and heterogeneity in multi-omics data reduce predictive power.
method Omics-GAN is a GAN-based framework that generates high-quality synthetic multi-omics profiles.
result Synthetic datasets consistently improved prediction accuracy compared to original omics profiles.
PNNs improve treatment outcomes in TAVR and liver trauma.
problem Improving treatment outcomes in medical procedures.
method Multimodal Prescriptive Neural Networks (PNNs) combining optimization and machine learning.
result PNNs significantly improve estimated outcomes in medical procedures.
In this paper we present a new method for motion tracking of tumors in liver ultrasound image sequences. Our algorithm has two main steps. In the first step, we apply mean shift algorithm with multiple features to estimate the center of the target in each frame. Target in the first frame is defined using an ellipse. Ed…
Machine Learning Approaches for Binary Classification to Discover Liver Diseases using Clinical Datastat.ML
Paper uses ML to classify liver diseases from clinical data.
problem Classifying liver diseases from clinical data.
method Multiple imputation, PCA, data visualizations, binary classifier algorithms (ANN, RF, SVM).
result SVM showed better accuracy (98.23%).
AI system helps clinicians assess liver metastases quickly and with explanations.
problem Manual assessment of metastases is time-consuming and subjective.
method Interactive AI system with model interpretability.
result AI-assisted assessment improves efficiency and provides explanations.
New method for finding optimal treatment regimes in medical settings with time-varying unobserved factors.
problem Finding optimal treatment regimes in medical settings with time-varying unobserved factors.
method Extend Dynamic Treatment Regimes (DTRs) to Ambiguous Dynamic Treatment Regimes (ADTRs), connect to Ambiguous Partially Observable Mark Decision Processes (APOMDPs), and develop Reinforcement Learning methods.
result Established theoretical results for learning methods, including consistency and asymptotic normality.
Deformation estimation of elastic object assuming an internal organ is important for the computer navigation of surgery. The aim of this study is to estimate the deformation of an entire three-dimensional elastic object using displacement information of very few observation points. A learning approach with a neural net…
This paper presents the first deep reinforcement learning (DRL) framework to estimate the optimal Dynamic Treatment Regimes from observational medical data. This framework is more flexible and adaptive for high dimensional action and state spaces than existing reinforcement learning methods to model real-life complexit…
We prove that C. Loewner's inequality for the torus is satisfied by all hyperelliptic surfaces X, as well. We first construct the Loewner loops on the (mildly singular) companion tori, locally isometric to X away from the Weierstrass points. The loops are then transplanted to X, and surgered to obtain a Loewner loop on…
Developed mlf-core for deterministic machine learning.
problem Ensuring machine learning models are deterministic for verification.
method Formulated requirements, developed mlf-core ecosystem, tested various models.
result Demonstrated deterministic models in biomedical fields.
Framework predicts mortality risk in MAFLD subjects.
problem Lack of mortality prediction methods for MAFLD subjects.
method Artificial Intelligence-based framework MAFUS using ML algorithms.
result Support Vector Machines (SVM) is the best model for mortality prediction.
A Neural Network Model to Classify Liver Cancer Patients Using Data Expansion and Compressionstat.ML
We develop a neural network model to classify liver cancer patients into high-risk and low-risk groups using genomic data. Our approach provides a novel technique to classify big data sets using neural network models. We preprocess the data before training the neural network models. We first expand the data using wavel…
Paper presents an ensemble model for predicting readmission using clinical notes.
problem Limited use of clinical notes in predicting readmission due to their unstructured nature.
method Ensemble model combining vector space modeling and topic modeling.
result Improves readmission prediction by 0.0211 in c-statistics.
Bayesian framework improves minority class performance in class-imbalanced data.
problem Class imbalance in predictive toxicology models.
method Weighted likelihood approach modifying likelihood function weights inversely proportional to class proportions.
result Improves balanced accuracy and sensitivity for minority class (toxic compounds).
Introduction. Case Based Reasoning (CBR) is an emerg- ing decision making paradigm in medical research where new cases are solved relying on previously solved similar cases. Usually, a database of solved cases is provided, and every case is described through a set of attributes (inputs) and a label (output). Extracting…
Machine learning builds personalized pediatric abdominal phantoms.
problem Lack of individualized phantoms for radiation therapy studies.
method Combining imaging and machine learning to automatically build phantoms.
result Automatically constructed phantoms more accurately represent patient anatomy.
Method predicts NAFLD risk with high accuracy and distribution-free coverage guarantees.
problem Insufficient population-level screening tools for NAFLD.
method Gradient-boosted decision trees with conformal prediction.
result Method achieves AUROC of 0.912 internally and 0.891 externally, superior to other models.
New energy measure for isolated systems in general relativity.
problem Quantifying energy in isolated systems in general relativity.
method Optimal isometric embedding and conformal Killing fields.
result Finite quasi-local energies for asymptotically flat spacetimes.
Given a hyperelliptic Klein surface, we construct companion Klein bottles, extending our technique of companion tori already exploited by the authors in the genus 2 case. Bavard's short loops on such companion surfaces are studied in relation to the original surface so to improve a systolic inequality of Gromov's. A ba…
Generates synthetic laparoscopic images for training deep neural networks.
problem Lack of large labeled data sets for laparoscopic image processing.
method Unpaired image-to-image translation to generate realistic synthetic images.
result Synthetic data set improves liver segmentation performance without manual labeling.
Although much progress has been made in classification with high-dimensional features \citep{Fan_Fan:2008, JGuo:2010, CaiSun:2014, PRXu:2014}, classification with ultrahigh-dimensional features, wherein the features much outnumber the sample size, defies most existing work. This paper introduces a novel and computation…
The paper examines how macroeconomic control tools lost effectiveness, leading to a 'dark ages' period.
problem Loss of effectiveness of control tools in macroeconomic stabilization policy.
method Historical analysis of macroeconomic stabilization policy from 1948 to 1993.
result The overstatement of the Lucas critique and Kydland and Prescott's time-inconsistency led to a period of ineffective stabilization policy.
In this work we propose a method for anatomical data augmentation that is based on using slices of computed tomography (CT) examinations that are adjacent to labeled slices as another resource of labeled data for training the network. The extended labeled data is used to train a U-net network for a pixel-wise classific…
This article considers the quasi-local conserved quantities with respect to a reference spacetime with a cosmological constant. We follow the approach developed by the authors in [25,26,7] and define the quasi-local energy as differences of surface Hamiltonians. The ground state for the gravitational energy is taken to…
The paper proposes a semi-parametric Bayesian network model using Gaussian Processes and Horseshoe priors.
problem Learning semi-parametric relationships in Expert Bayesian Networks with minimal nonlinear components.
method Uses Gaussian Processes and Horseshoe priors to model relationships, prioritizes modifying expert graphs, and generates diverse graphs.
result Models outperform state-of-the-art semi-parametric Bayesian Network models in synthetic and real-world datasets.
We present *K-means clustering algorithm and source code by expanding statistical clustering methods applied in https://ssrn.com/abstract=2802753 to quantitative finance. *K-means is statistically deterministic without specifying initial centers, etc. We apply *K-means to extracting cancer signatures from genome data w…
A-kNN improves kNN's ability to classify unknown instances.
problem kNN's inability to predict unknown instances.
method Developed Advanced kNN (A-kNN) algorithm.
result A-kNN significantly improves accuracy in classifying unknown instances.
Novel unsupervised method for fast 3D image registration using cycle-consistent CNN.
problem Medical image registration for cancer diagnosis.
method Unsupervised deep learning using cycle-consistent CNN for deformable registration.
result Very precise 3D image registration within a few seconds, improving cancer size estimation.
In this paper, by extending the notions of harmonic transplantation and harmonic radius in the Heisenberg group, we give an upper bound for the first eigenvalue for the following Dirichlet problem: $$(P_Ω) \left\{ \begin{array}{lllll} -Δ_{\mathbb{H}^1} u & = & λu & \mbox{in} & Ωu & = & 0 & \mbox{on} & \partial Ω, \end{…
We present a novel method for extracting cancer signatures by applying statistical risk models (http://ssrn.com/abstract=2732453) from quantitative finance to cancer genome data. Using 1389 whole genome sequenced samples from 14 cancers, we identify an "overall" mode of somatic mutational noise. We give a prescription …