Study proposes managing COVID-19 without economy shutdowns.
problem Avoiding lockdowns while maintaining healthcare system capacity.
method Detailed heterogeneous epidemiological model, calibrated to data.
result Countries can avoid lockdowns if ICU beds per million > 100.
New model predicts ICU patients' stay duration efficiently.
problem Efficient ICU bed allocation under resource constraints.
method Temporal Pointwise Convolution (TPC) model combining temporal and pointwise convolutions.
result Significant performance improvements over LSTM and Transformer models.
New model predicts ICU patient stays more accurately.
problem Efficient ICU bed allocation under resource constraints.
method Temporal Pointwise Convolutional Networks (TPC) combining temporal and pointwise convolutions.
result Significant performance improvements over LSTM and Transformer models.
Estimates future ICU demand using age-structured data and logistic modeling.
problem Projecting future ICU demand from low-quality data.
method Age-structured sampling, logistic fit, subnotification factor correction.
result Corrected logistic curve projects future ICU demand.
Monitoring patients in ICU is a challenging and high-cost task. Hence, predicting the condition of patients during their ICU stay can help provide better acute care and plan the hospital's resources. There has been continuous progress in machine learning research for ICU management, and most of this work has focused on…
Proposes proactive bed requests to reduce ED boarding and patient wait times.
problem Reduces ED boarding and patient wait times by proactively requesting inpatient beds.
method Formulates as a Markov decision process, uses predictions of admission probability and time to disposition to guide bed requests.
result Proactive aggregate bed requests can reduce boarding times by 30-70% and length of stay by 6-15%.
Study predicts future hospitalizations to manage COVID-19 patient surge.
problem Managing hospitalization needs during COVID-19 pandemic.
method Used 4 recurrent neural networks to predict hospitalization changes.
result Sequence to sequence model with attention achieved high accuracy and AUC.
HOLMES improves real-time model serving for ICU patients, balancing accuracy and speed.
problem Real-time model serving is crucial in ICU due to urgency and cost.
method Online model ensemble serving framework for healthcare applications.
result HOLMES achieves high accuracy and sub-second latency for model ensemble serving.
Study analyzes sensitivity of RL algorithm for ICU hemodynamic management.
problem Evaluating safety and reliability of RL in clinical settings.
method Sensitivity analysis of Duel-DDQN on ICU sepsis patients.
result RL policies are sensitive to various implementation factors.
Method uses random forest with distance covariance for transfer learning in healthcare.
problem Transfer learning in random forests with sparse differences between source and target.
method Distance covariance-based feature weights in residual random forest.
result Upper bound on mean square error rate for transfer learning in RF.
CO-BED optimizes experiments using Bayesian methods and information theory.
problem Optimizing experiments in a context-dependent manner.
method Formalizes contextual optimization with Bayesian experimental design, employing information-theoretic principles and black-box variational methods.
result CO-BED provides a general solution for contextual optimization problems.
The paper develops a method to predict ICU mortality risk across diverse patient populations.
problem Improving patient survival by recognizing risky trajectories during ICU stays.
method Domain adaptation strategies to learn mortality prediction models robust to diverse ICU populations.
result The proposed model outperforms baselines, achieving AUC numbers up to 0.88 for the Cardiac ICU population.
Action-BED: Task-Driven Bayesian Experimental Design
problem Bayesian experimental design with doubly intractable objectives
method Formulating BED in terms of expected future loss (EFL) and optimising it with stochastic gradients
result Simplified and task-driven framework for BED
Step-DAD improves BED by periodically updating a design policy during experiments.
problem Improving flexibility and robustness in Bayesian experimental design.
method Semi-amortized, policy-based approach that updates a design policy during data collection.
result Consistently superior decision-making and robustness compared to current BED methods.
New method optimizes experiments under constraints.
problem Adapting BED to dynamic constraints in real-world tasks.
method Offline pre-training of an amortized policy and posterior network with online multi-step lookahead planning.
result Significantly more informative design sequences than existing methods.
Predictive models identify patients at risk of severe COVID-19.
problem Identifying patients at risk of severe COVID-19 to ease healthcare strain.
method Machine learning on routinely collected clinical data.
result Models predict positive SARS-CoV-2 tests, hospitalizations, and critical care with high accuracy.
Study compares ARIMA, ETS, NNAR and hybrids for COVID-19 hospitalizations.
problem Forecasting the second wave of COVID-19 hospitalizations in Italy.
method ARIMA, ETS, NNAR, and hybrid models.
result Hybrid models outperform single models in capturing epidemic patterns.
Novel framework optimizes experiments for implicit models using mutual information.
problem Optimizing experiments for intractable implicit models.
method Sequential Bayesian Experimental Design using Mutual Information.
result Framework efficiently estimates parameters with few iterations.
Study developed phenotypes for ICU patients' brain dysfunction states.
problem Underdiagnosis of acute brain dysfunction in ICU patients.
method Created algorithms to quantify and cluster brain dysfunction states.
result Developed three phenotypes of ICU patients' brain dysfunction states.
BED-LLM uses Bayesian experimental design to improve LLMs' information gathering.
problem Improving LLMs' ability to gather information adaptively.
method Iteratively choosing questions to maximize expected information gain using a probabilistic model.
result BED-LLM achieves substantial performance gains compared to other adaptive design strategies.
Sepsis is the leading cause of mortality in the ICU. It is challenging to manage because individual patients respond differently to treatment. Thus, tailoring treatment to the individual patient is essential for the best outcomes. In this paper, we take steps toward this goal by applying a mixture-of-experts framework …
A scalable method for BED with implicit models using approximate gradients.
problem Efficiently estimating posterior distribution and maximizing MI for implicit models.
method Stochastic approximate gradient ascent with smoothed variational MI estimator.
result Significantly improves scalability of BED in high-dimensional problems.
Study develops electronic phenotypes of ICU patient acuity.
problem Limited time for patient acuity assessments and imprecise clinical trajectory prediction.
method Developed electronic phenotypes using automated variable retrieval in electronic health records.
result Identified three phenotypes: persistently stable, persistently unstable, and transitioning from unstable to stable.
Good predictors of ICU Mortality have the potential to identify high-risk patients earlier, improve ICU resource allocation, or create more accurate population-level risk models. Machine learning practitioners typically make choices about how to represent features in a particular model, but these choices are seldom eva…
Study identifies sepsis subpopulations for better ICU prediction.
problem Lack of stratified sepsis subpopulations in ICU EHR predictions.
method Stratified sepsis subpopulations identified using machine learning.
result Machine learning models perform better with stratified subpopulations.
Robust policies improve ICU transfer outcomes by predicting patient deterioration.
problem Higher mortality rates for unplanned ICU transfers.
method Markov Decision Process model to predict patient severity and optimize transfer policies.
result Robust policies are more aggressive in transferring patients than nominal policies, improving overall patient care.
Study describes severe dengue ICU patients in Brazil, 2012-2024.
problem Characterize severe dengue ICU patients and identify risk factors.
method Prospective study, descriptive statistics, logistic regression, machine learning.
result Advanced age, comorbidities, leukocytes, and platelets are significant risk factors for complications.
Emergent and unscheduled cardiology admissions from cardiac catheterization laboratory add complexity to the management of Cardiology and in-patient department. In this article, we sought to study the behavior of cardiology admissions from Catheterization laboratory using time series models. Our research involves retro…
Late fusion of clinical notes and physiological data improves ICU mortality prediction.
problem Improving ICU mortality prediction using multimodal data.
method Late fusion of clinical notes and physiological time series data with a deep learning architecture.
result Late fusion approach provides statistically significant improvement in mortality prediction performance.
Novel metrics improve machine learning models for ICU patient care.
problem Predicting vital sign trajectories for early detection of adverse events.
method Developed novel performance metrics aligned with clinical contexts, validated on simulated and real datasets, and optimized neural networks using these metrics.
result Neural networks trained with these metrics excel in predicting clinically significant events.
Modeling physiological time-series in ICU is of high clinical importance. However, data collected within ICU are irregular in time and often contain missing measurements. Since absence of a measure would signify its lack of importance, the missingness is indeed informative and might reflect the decision making by the c…
Bayesian design improves experimental optimization.
problem Computational challenges limit BED practical use.
method Recent advances in BED have reduced computational burdens.
result Effective BED design is now feasible.
We considered observational data available from the MIMIC-III open-access ICU database and collected within a study period between year 2002 up to 2011. If a patient had multiple admissions to the ICU during the 30 days before death, only the first stay was analyzed, leading to a final set of 6,436 unique ICU admission…
ICU readmission is associated with longer hospitalization, mortality and adverse outcomes. An early recognition of ICU re-admission can help prevent patients from worse situation and lower treatment cost. As the abundance of Electronics Health Records (EHR), it is popular to design clinical decision tools with machine …
Paper uses RL to optimize ICU load during COVID-19.
problem Optimizing ICU load during a pandemic.
method Combines epidemic model, Bayesian inference, and RL for adaptive intervention levels.
result RL policies reduce ICU burden compared to historical interventions.
WRSE predicts dynamic survival distributions in ICU patients.
problem Dynamic assessment of ICU patient mortality risk.
method Non-parametric weighted-resolution ensemble model combining binary classifiers.
result Competitive results with state-of-the-art models, reducing training time.
The ability to perform effective off-policy learning would revolutionize the process of building better interactive systems, such as search engines and recommendation systems for e-commerce, computational advertising and news. Recent approaches for off-policy evaluation and learning in these settings appear promising. …
Bayesian model detects internal bleeding in ICU patients.
problem Late detection of internal bleeding in ICU patients.
method Bayesian regime switching model analyzing vitals and labs.
result Probabilistic assessment of patient's physiological state.
The paper tackles ICU discharge strategies by evaluating optimal stopping scenarios.
problem Optimal stopping in ICU discharge with complex causal inference challenges.
method Generalized g-formula implementation and application to MIMIC-IV dataset.
result Improved ICU discharge strategies demonstrated with the g-formula approach.
Deep learning predicts ICU mortality with enhanced interpretability.
problem Improving mortality prediction accuracy and clinician trust in AI.
method Trained a deep learning model on MIMIC-III to interpret nursing notes.
result Model reaches ROC of 0.8629, outperforming SAPS-II.
Objective: Predict patient-specific vitals deemed medically acceptable for discharge from a pediatric intensive care unit (ICU). Design: The means of each patient's hr, sbp and dbp measurements between their medical and physical discharge from the ICU were computed as a proxy for their physiologically acceptable state …
Bayesian method estimates dynamics from near-optimal trajectories.
problem Estimating dynamics from near-optimal expert trajectories in reinforcement learning.
method Constraint-based Bayesian approach integrating expert near-optimality.
result Significant improvements in decision-making and transfer success.
System predicts respiratory failure up to 8 hours early.
problem Early detection of respiratory failure in ICU patients.
method Machine learning on ICU patient monitoring data.
result System outperforms traditional clinical decision-making.
Bedside monitors in Intensive Care Units (ICUs) frequently sound incorrectly, slowing response times and desensitising nurses to alarms (Chambrin, 2001), causing true alarms to be missed (Hug et al., 2011). We compare sliding window predictors with recurrent predictors to classify patient state-of-health from ICU multi…
Novel IRL method identifies suboptimal medical decisions in ICU data.
problem Identifying suboptimal medical decisions in clinical settings.
method Incorporates Inverse Reinforcement Learning with a pruning step to identify and remove suboptimal actions.
result Pruning step effectively identifies clinical priorities and values from suboptimal data.
Study improves mortality prediction in ICU patients using feature engineering and 1D CNN.
problem Improving mortality prediction in ICU patients with high-dimensional, imbalanced, and missing data.
method Feature engineering, 1D Convolutional Neural Network (1D CNN), traditional machine learning algorithms.
result Best AUC of 0.848 achieved with 1D CNN model.
Dual ML approach predicts peak temperatures in AFSD, improving process optimization.
problem Lack of understanding between process parameters and resulting microstructure in AFSD.
method Combines supervised machine learning and physics-informed neural networks.
result Ensemble techniques like gradient boosting outperform other SML methods in predicting peak temperatures.
Designs a single-sensor system for accurate lying posture detection.
problem Designing efficient in-bed lying posture tracking systems.
method Single accelerometer with machine learning algorithms (deep learning and traditional classification).
result Single accelerometer can accurately detect lying postures with high F-Score.