The paper uses AI to analyze ECG data, revealing age-related changes and identifying key features.
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Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further establish the credentials of "brain-predicted age" as a biomarker of individual differe…
SFCNeXt estimates brain age from small MRI datasets.
Accurate diagnosis is crucial for preventing the progression of Parkinson's, as well as improving the quality of life with individuals with Parkinson's disease. In this paper, we develop a sex-specific and age-dependent classification method to diagnose the Parkinson's disease using the online handwriting recorded from…
Background and objectives: Parkinson's disease is a neurological disorder that affects the motor system producing lack of coordination, resting tremor, and rigidity. Impairments in handwriting are among the main symptoms of the disease. Handwriting analysis can help in supporting the diagnosis and in monitoring the pro…
Diagnosis and treatment guidance are aided by detecting relevant biomarkers in medical images. Although supervised deep learning can perform accurate segmentation of pathological areas, it is limited by requiring a-priori definitions of these regions, large-scale annotations, and a representative patient cohort in the …
Who {\em values} life annuities more? Is it the healthy retiree who expects to live long and might become a centenarian, or is the unhealthy retiree with a short life expectancy more likely to appreciate the pooling of longevity risk? What if the unhealthy retiree is pooled with someone who is much healthier and thus f…
We describe a new method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on multidimensional classification of hippocampal shape features. This approach uses spherical harmonics (SPHARM) coefficients to model the shape of the hi…
Speech datasets for identifying Alzheimer's disease (AD) are generally restricted to participants performing a single task, e.g. describing an image shown to them. As a result, models trained on linguistic features derived from such datasets may not be generalizable across tasks. Building on prior work demonstrating th…
A cascaded multi-planar scheme with a modified residual U-Net architecture was used to segment thalamic nuclei on conventional and white-matter-nulled (WMn) magnetization prepared rapid gradient echo (MPRAGE) data. A single network was optimized to work with images from healthy controls and patients with multiple scler…
The study of healthy brain development helps to better understand the brain transformation and brain connectivity patterns which happen during childhood to adulthood. This study presents a sparse machine learning solution across whole-brain functional connectivity (FC) measures of three sets of data, derived from resti…
Pseudo healthy synthesis, i.e. the creation of a subject-specific `healthy' image from a pathological one, could be helpful in tasks such as anomaly detection, understanding changes induced by pathology and disease or even as data augmentation. We treat this task as a factor decomposition problem: we aim to separate wh…
In this study, we tested the interaction effect of multimodal datasets using a novel method called the kernel method for detecting higher order interactions among biologically relevant mulit-view data. Using a semiparametric method on a reproducing kernel Hilbert space (RKHS), we used a standard mixed-effects linear mo…
Method converts age labels into distributions to improve speaker age estimation.
A Longitudinal Attribute-Conditioned Neural Network (LANTERN) framework for modeling health-state transition probabilities in irregular longitudinal data.
Preterm newborns undergo various stresses that may materialize as learning problems at school-age. Sleep staging of the Electroencephalogram (EEG), followed by prediction of their brain-age from these sleep states can quantify deviations from normal brain development early (when compared to the known age). Current auto…
The specificty and sensitivity of resting state functional MRI (rs-fMRI) measurements depend on pre-processing choices, such as the parcellation scheme used to define regions of interest (ROIs). In this study, we critically evaluate the effect of brain parcellations on machine learning models applied to rs-fMRI data. O…
We solve a lifecycle model in which the consumer's chronological age does not move in lockstep with calendar time. Instead, biological age increases at a stochastic non-linear rate in time like a broken clock that might occasionally move backwards. In other words, biological age could actually decline. Our paper is ins…
Despite the remarkable progress in face recognition related technologies, reliably recognizing faces across ages still remains a big challenge. The appearance of a human face changes substantially over time, resulting in significant intra-class variations. As opposed to current techniques for age-invariant face recogni…
We discuss a simple, exactly solvable model of stochastic stock dynamics that incorporates regime switching between healthy and distressed regimes. Using this model, which is analytically tractable, we discuss a way of extracting expected returns for stocks from realized CDS spreads, essentially, the CDS market sentime…
Learning to automatically perceive smell is becoming increasingly important with applications in monitoring the quality of food and drinks for healthy living. In todays age of proliferation of internet of things devices, the deployment of electronic nose otherwise known as smell sensors is on the increase for a variety…
ADReSS Challenge at INTERSPEECH 2020 benchmarks speech recognition for Alzheimer's dementia.
BSD is a Bayesian framework for analyzing neural spectral data.
Evidence suggests Rapid-Eye-Movement (REM) Sleep Behaviour Disorder (RBD) is an early predictor of Parkinson's disease. This study proposes a fully-automated framework for RBD detection consisting of automated sleep staging followed by RBD identification. Analysis was assessed using a limited polysomnography montage fr…
Bayesian CNN estimates uncertainty in bone age prediction.
Detects domain shifts in datasets using interpretable feature subspaces.
Develops a method to analyze SARS-CoV-2 viral load vs. age, finding a significant increase.
Fetal brain imaging is a cornerstone of prenatal screening and early diagnosis of congenital anomalies. Knowledge of fetal gestational age is the key to the accurate assessment of brain development. This study develops an attention-based deep learning model to predict gestational age of the fetal brain. The proposed mo…
Twitter provides an open and rich source of data for studying human behaviour at scale and is widely used in social and network sciences. However, a major criticism of Twitter data is that demographic information is largely absent. Enhancing Twitter data with user ages would advance our ability to study social network …
Human brain development is rapid during infancy and early childhood. Many disease processes impair this development. Therefore, brain developmental age estimation (BDAE) is essential for all diseases affecting cognitive development. Brain magnetic resonance imaging (MRI) of infants shows brain growth and morphologic pa…
One of the most prevalent symptoms among the elderly population, dementia, can be detected by classifiers trained on linguistic features extracted from narrative transcripts. However, these linguistic features are impacted in a similar but different fashion by the normal aging process. Aging is therefore a confounding …
Novel method detects faults in helicopter transmissions using healthy data only.
Estimates future ICU demand using age-structured data and logistic modeling.
Novel U-learning method for predicting continuous outcomes from high-dimensional data.
In power systems, an asset class is a group of power equipment that has the same function and shares similar electrical or mechanical characteristics. Predicting failures for different asset classes is critical for electric utilities towards developing cost-effective asset management strategies. Previously, physical ag…
Accelerated gradient (AG) methods are breakthroughs in convex optimization, improving the convergence rate of the gradient descent method for optimization with smooth functions. However, the analysis of AG methods for non-convex optimization is still limited. It remains an open question whether AG methods from convex o…
Italy's daily COVID-19 cases stratified by age groups.
A new FL algorithm reduces communication overhead by selectively updating model parameters.
Improved 3D MRI classification using contrastive learning with continuous proxy metadata.
AGE improves graph embedding by smoothing features and iteratively enhancing node embeddings.
SepVAE separates patient-specific patterns from healthy ones using contrastive VAE.
Study reveals that cryptocurrency price variations follow power-law distributions, influenced by age and market capitalization.
From a young age humans learn to use grammatical principles to hierarchically combine words into sentences. Action grammars is the parallel idea, that there is an underlying set of rules (a "grammar") that govern how we hierarchically combine actions to form new, more complex actions. We introduce the Action Grammar Re…
Machine learning models predict brain age with systematic bias, corrected in this study.
Proposes a new model for mortality forecasting considering age groups and cohort effects.
Optimal annuitization strategy depends on age, labor income, and mortality risk.
This paper solves the problem of optimal dynamic consumption, investment, and healthcare spending with isoelastic utility, when natural mortality grows exponentially to reflect Gompertz' law and investment opportunities are constant. Healthcare slows the natural growth of mortality, indirectly increasing utility from c…
VNNs transfer well across datasets for brain age prediction using cortical thickness features.