arXiv research

We target modeling latent dynamics in high-dimension marked event sequences without any prior knowledge about marker relations. Such problem has been rarely studied by previous works which would have fundamental difficulty to handle the arisen challenges: 1) the high-dimensional markers and unknown relation network amo…

CNMs detect tipping points in complex systems using causal network markers.

Study uses DNM theory to detect early warning signals of market instability.

Predicts clinical events using a landmark approach with machine learning for large biomarker histories.

Novel method identifies proteomic risk markers for Alzheimer disease.

Improves disease progression prediction using auxiliary surrogate labels and health markers.

Preterm birth is the most common cause of neonatal death. Current diagnostic methods that assess the risk of preterm birth involve the collection of maternal characteristics and transvaginal ultrasound imaging conducted in the first and second trimester of pregnancy. Analysis of the ultrasound data is based on visual i…

Feature selection predicts immune state changes in RA mouse model.

Neural network training entails heavy computation with obvious bottlenecks. The Compute Unified Device Architecture (CUDA) programming model allows us to accelerate computation by passing the processing workload from the CPU to the graphics processing unit (GPU). In this paper, we leveraged the power of Nvidia GPUs to …

As societies around the world are ageing, the number of Alzheimer's disease (AD) patients is rapidly increasing. To date, no low-cost, non-invasive biomarkers have been established to advance the objectivization of AD diagnosis and progression assessment. Here, we utilize Bayesian neural networks to develop a multivari…

Many complex disease syndromes such as asthma consist of a large number of highly related, rather than independent, clinical phenotypes, raising a new technical challenge in identifying genetic variations associated simultaneously with correlated traits. In this study, we propose a new statistical framework called grap…

AR app visualizes Quranic Surah al-Fil for Islamic education.

Quantifying behavior is crucial for many applications in neuroscience. Videography provides easy methods for the observation and recording of animal behavior in diverse settings, yet extracting particular aspects of a behavior for further analysis can be highly time consuming. In motor control studies, humans or other …

For precision medicine and personalized treatment, we need to identify predictive markers of disease. We focus on Alzheimer's disease (AD), where magnetic resonance imaging scans provide information about the disease status. By combining imaging with genome sequencing, we aim at identifying rare genetic markers associa…

Microbial clades modeling is a challenging problem in biology based on microarray genome sequences, especially in new species gene isolates discovery and category. Marker family genome sequences play important roles in describing specific microbial clades within species, a framework of support vector machine (SVM) base…

MarkerMap selects key genes for cell type analysis in single-cell RNA-seq.

This paper introduces the factorial marked temporal point process model and presents efficient learning methods. In conventional (multi-dimensional) marked temporal point process models, event is often encoded by a single discrete variable i.e. a marker. In this paper, we describe the factorial marked point processes w…

ST-GCN improves rs-fMRI prediction accuracy by modeling spatio-temporal graph connectivity.

The diagnosis of Alzheimer's disease (AD) in routine clinical practice is most commonly based on subjective clinical interpretations. Quantitative electroencephalography (QEEG) measures have been shown to reflect neurodegenerative processes in AD and might qualify as affordable and thereby widely available markers to f…

Neural networks outperform conventional filters in inertial sensor-based attitude estimation.

Proposes a two-stage method for estimating heterogeneous treatment effects using gradient boosting trees.

SimCD simultaneously clusters cells and identifies differential gene expression in scRNA-seq data.

fiBAG integrates multiplatform genomic data to identify disease markers.

Estimation of facial expressions, as spatio-temporal processes, can take advantage of kernel methods if one considers facial landmark positions and their motion in 3D space. We applied support vector classification with kernels derived from dynamic time-warping similarity measures. We achieved over 99% accuracy - measu…

Understanding cell identity is an important task in many biomedical areas. Expression patterns of specific marker genes have been used to characterize some limited cell types, but exclusive markers are not available for many cell types. A second approach is to use machine learning to discriminate cell types based on th…

We describe a method that infers whether statistical dependences between two observed variables X and Y are due to a "direct" causal link or only due to a connecting causal path that contains an unobserved variable of low complexity, e.g., a binary variable. This problem is motivated by statistical genetics. Given a ge…

The paper proposes a method to integrate prior information into penalized regression.

Falls prevention, especially in older people, becomes an increasingly important topic in the times of aging societies. In this work, we present Gated Recurrent Unit-based neural networks models designed for predicting falls (syncope). The cardiovascular systems signals used in the study come from Gravitational Physiolo…

While the prevalence of Autism Spectrum Disorder (ASD) is increasing, research continues in an effort to identify common etiological and pathophysiological bases. In this regard, modern machine learning and network science pave the way for a better understanding of the neuropathology and the development of diagnosis ai…

We consider the task of detecting regulatory elements in the human genome directly from raw DNA. Past work has focused on small snippets of DNA, making it difficult to model long-distance dependencies that arise from DNA's 3-dimensional conformation. In order to study long-distance dependencies, we develop and release …

The paper proposes a method to assess surrogate heterogeneity in non-randomized data.

The paper analyzes the observability of relative pose estimation using dual quaternions.

Sparse neural networks visualize paired transcriptomic and electrophysiological data.

Computer Vision and machine learning methods were previously used to reveal screen presence of genders in TV and movies. In this work, using head pose, gender detection, and skin color estimation techniques, we demonstrate that the gender disparity in TV in a South Asian country such as Bangladesh exhibits unique chara…

Discovering causal genetic variants from large genetic association studies poses many difficult challenges. Assessing which genetic markers are involved in determining trait status is a computationally demanding task, especially in the presence of gene-gene interactions. A non-parametric Bayesian approach in the form o…

Study improves survival analysis for credit risk by accounting for data drift.

Treatment effects can be estimated from observational data as the difference in potential outcomes. In this paper, we address the challenge of estimating the potential outcome when treatment-dose levels can vary continuously over time. Further, the outcome variable may not be measured at a regular frequency. Our propos…

We consider the hypothesis testing problem of detecting conditional dependence, with a focus on high-dimensional feature spaces. Our contribution is a new test statistic based on samples from a generative adversarial network designed to approximate directly a conditional distribution that encodes the null hypothesis, i…

AR app enhances young children's understanding of Wudhu.

RVGP learns vector fields over unknown manifolds, preserving singularities.

We present analytical exploration of novel activation functions as consequence of integration of several ideas leading to implementation and subsequent use in habitability classification of exoplanets. Neural networks, although a powerful engine in supervised methods, often require expensive tuning efforts for optimize…

While theories postulating a dual cognitive system take hold, quantitative confirmations are still needed to understand and identify interactions between the two systems or conflict events. Eye movements are among the most direct markers of the individual attentive load and may serve as an important proxy of informatio…

DynForest predicts event probabilities from longitudinal data, handling endogenous predictors.

A new neural network captures and explains trajectory patterns.

The multi-scale, mutli-physics nature of fusion plasmas makes predicting plasma events challenging. Recent advances in deep convolutional neural network architectures (CNN) utilizing dilated convolutions enable accurate predictions on sequences which have long-range, multi-scale characteristics, such as the time-series…

In this paper we extend the market-making models with inventory constraints of Avellaneda and Stoikov ("High-frequency trading in a limit-order book", Quantitative Finance Vol.8 No.3 2008) and Gueant, Lehalle and Fernandez-Tapia ("Dealing with inventory risk", Preprint 2011) to the case of a rather general class of mid…

Let R be an o-minimal expansion of the real field. We introduce a class of Hausdorff limits, the T-infinity limits over R, that do not in general fall under the scope of Marker and Steinhorn's definability-of-types theorem. We prove that if R admits analytic cell decomposition, then every T-infinity limit over R is def…

Locally sparse neural networks improve interpretability for biomedical tabular data.