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0111 · Jun 202519922001200920172026
1 result for DEG-aware

New metrics improve scRNA-seq perturbation modeling by reducing mode collapse.

problem Outperformed by simple mean prediction in scRNA-seq perturbation modeling.
method Introduce DEG-aware metrics (WMSE, Rw2(Δ)R^{2}_{w}(Δ)) and negative/positive baselines.
result WMSE loss function reduces mode collapse and improves model performance.