Neural network predicts cardiovascular events from EHRs with high accuracy.
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Study proposes a multimodal model for cardiovascular risk prediction using EHRs.
Method generates natural ECGs with 25 interpretable features.
BoXHED boosts hazard estimation for dynamic health risk scores.
Guidelines for the management of atherosclerotic cardiovascular disease (ASCVD) recommend the use of risk stratification models to identify patients most likely to benefit from cholesterol-lowering and other therapies. These models have differential performance across race and gender groups with inconsistent behavior a…
Study creates a multimodal learning framework for CVD risk prediction.
Cardiovascular diseases are one of the most common causes of death in the world. Prevention, knowledge of previous cases in the family, and early detection is the best strategy to reduce this fact. Different machine learning approaches to automatic diagnostic are being proposed to this task. As in most health problems,…
Heart disease is one of the most common diseases in middle-aged citizens. Among the vast number of heart diseases, the coronary artery disease (CAD) is considered as a common cardiovascular disease with a high death rate. The most popular tool for diagnosing CAD is the use of medical imaging, e.g., angiography. However…
Radiomics identifies subtle cardiac changes in hypertension.
Deep learning improves CVD risk prediction from health records.
Portable, Wearable and Wireless electrocardiogram (ECG) Systems have the potential to be used as point-of-care for cardiovascular disease diagnostic systems. Such wearable and wireless ECG systems require automatic detection of cardiovascular disease. Even in the primary care, automation of ECG diagnostic systems will …
This paper presents a method for building patient-based networks that we call Precision disease networks, and its uses for predicting medical outcomes. Our methodology consists of building networks, one for each patient or case, that describes the dis-ease evolution of the patient (PDN) and store the networks as a set …
A new method for sampling from posterior distributions in Bayesian inverse problems.
Mobile electrocardiogram (ECG) recording technologies represent a promising tool to fight the ongoing epidemic of cardiovascular diseases, which are responsible for more deaths globally than any other cause. While the ability to monitor one's heart activity at any time in any place is a crucial advantage of such techno…
A clinician desires to use a risk-stratification method that achieves confident risk-stratification - the risk estimates of the different patients reflect the true risks with a high probability. This allows him/her to use these risks to make accurate predictions about prognosis and decisions about screening, treatments…
New test identifies specific biological parameters for personalized CVD detection.
Cardiovascular Disease (CVD) is considered as one of the principal causes of death in the world. Over recent years, this field of study has attracted researchers' attention to investigate heart sounds' patterns for disease diagnostics. In this study, an approach is proposed for normal/abnormal heart sound classificatio…
Patient subtyping based on temporal observations can lead to significantly nuanced subtyping that acknowledges the dynamic characteristics of diseases. Existing methods for subtyping trajectories treat the evolution of clinical observations as a homogeneous process or employ data available at regular intervals. In real…
We study regularized estimation in high-dimensional longitudinal classification problems, using the lasso and fused lasso regularizers. The constructed coefficient estimates are piecewise constant across the time dimension in the longitudinal problem, with adaptively selected change points (break points). We present an…
Study finds incorporating fairness in healthcare models doesn't improve performance or net benefit.
Hypertension is a major risk factor for stroke, cardiovascular disease, and end-stage renal disease, and its prevalence is expected to rise dramatically. Effective hypertension management is thus critical. A particular priority is decreasing the incidence of uncontrolled hypertension. Early identification of patients a…
Bayesian neural networks improve SHD classification and uncertainty quantification.
We consider the problem of modeling cardiovascular responses to physical activity and sleep changes captured by wearable sensors in free living conditions. We use an attentional convolutional neural network to learn parsimonious signatures of individual cardiovascular response from data recorded at the minute level res…
ECGDetect uses deep learning to detect ischemia in heart ECGs.
After admission to emergency department (ED), patients with critical illnesses are transferred to intensive care unit (ICU) due to unexpected clinical deterioration occurrence. Identifying such unplanned ICU transfers is urgently needed for medical physicians to achieve two-fold goals: improving critical care quality a…
Patients who suffer an acute coronary syndrome are at elevated risk for adverse cardiovascular events such as myocardial infarction and cardiovascular death. Accurate assessment of this risk is crucial to their course of care. We focus on estimating a patient's risk of cardiovascular death after an acute coronary syndr…
In the United States, heart disease is the leading cause of death for both men and women, accounting for 610,000 deaths each year [1]. Physicians use Magnetic Resonance Imaging (MRI) scans to take images of the heart in order to non-invasively estimate its structural and functional parameters for cardiovascular diagnos…
Study predicts heart failure patient survival using stacked ensemble ML.
SBI improves uncertainty analysis of cardiovascular biomarkers.
The morphological structure of left ventricle segmented from cardiac magnetic resonance images can be used to calculate key clinical parameters, and it is of great significance to the accurate and efficient diagnosis of cardiovascular diseases. Compared with traditional methods, the segmentation algorithms based on ful…
Acceleration of machine learning research in healthcare is challenged by lack of large annotated and balanced datasets. Furthermore, dealing with measurement inaccuracies and exploiting unsupervised data are considered to be central to improving existing solutions. In particular, a primary objective in predictive model…
Method predicts NAFLD risk with high accuracy and distribution-free coverage guarantees.
The paper uses AI to analyze ECG data, revealing age-related changes and identifying key features.
The retinal vascular condition is a reliable biomarker of several ophthalmologic and cardiovascular diseases, so automatic vessel segmentation may be crucial to diagnose and monitor them. In this paper, we propose a novel method that combines the multiscale analysis provided by the Stationary Wavelet Transform with a m…
Current clinical practice guidelines for managing Coronary Artery Disease (CAD) account for general cardiovascular risk factors. However, they do not present a framework that considers personalized patient-specific characteristics. Using the electronic health records of 21,460 patients, we created data-driven models fo…
Researchers develop methods to reduce simulation costs for cardiovascular modeling.
Type 2 Diabetes (T2D) is a chronic metabolic disorder that can lead to blindness and cardiovascular disease. Information about early stage T2D might be present in retinal fundus images, but to what extent these images can be used for a screening setting is still unknown. In this study, deep neural networks were employe…
Counterfactual explanations can be obtained by identifying the smallest change made to a feature vector to qualitatively influence a prediction; for example, from 'loan rejected' to 'awarded' or from 'high risk of cardiovascular disease' to 'low risk'. Previous approaches often emphasized that counterfactuals should be…
FalconBC improves patient-specific cardiovascular modeling by estimating boundary conditions efficiently.
Air quality is closely related to public health. Health issues such as cardiovascular diseases and respiratory diseases, may have connection with long exposure to highly polluted environment. Therefore, accurate air quality forecasts are extremely important to those who are vulnerable. To estimate the variation of seve…
Models for predicting the risk of cardiovascular events based on individual patient characteristics are important tools for managing patient care. Most current and commonly used risk prediction models have been built from carefully selected epidemiological cohorts. However, the homogeneity and limited size of such coho…
This study benchmarks changepoint detection algorithms on cardiac time series data.
We train and validate a semi-supervised, multi-task LSTM on 57,675 person-weeks of data from off-the-shelf wearable heart rate sensors, showing high accuracy at detecting multiple medical conditions, including diabetes (0.8451), high cholesterol (0.7441), high blood pressure (0.8086), and sleep apnea (0.8298). We compa…
Heart rate estimation from electrocardiogram signals is very important for the early detection of cardiovascular diseases. However, due to large individual differences and varying electrocardiogram signal quality, there does not exist a single reliable estimation algorithm that works well on all subjects. Every algorit…
Generative ODE model learns unknown variables in medical systems.
Framework for imputing missing heart data to simulate brain-heart interactions.
Inverse classification is the process of manipulating an instance such that it is more likely to conform to a specific class. Past methods that address such a problem have shortcomings. Greedy methods make changes that are overly radical, often relying on data that is strictly discrete. Other methods rely on certain da…
The widely used genetic pleiotropic analysis of multiple phenotypes are often designed for examining the relationship between common variants and a few phenotypes. They are not suited for both high dimensional phenotypes and high dimensional genotype (next-generation sequencing) data. To overcome these limitations, we …