SFCNeXt estimates brain age from small MRI datasets.
problem Efficiently estimating brain age from limited MRI data.
method Simple fully convolutional network (SFCNeXt) with SPEC and HRL.
result SFCNeXt outperforms complex models in small sample size scenarios.
Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further establish the credentials of "brain-predicted age" as a biomarker of individual differe…
Preterm newborns undergo various stresses that may materialize as learning problems at school-age. Sleep staging of the Electroencephalogram (EEG), followed by prediction of their brain-age from these sleep states can quantify deviations from normal brain development early (when compared to the known age). Current auto…
Fetal brain imaging is a cornerstone of prenatal screening and early diagnosis of congenital anomalies. Knowledge of fetal gestational age is the key to the accurate assessment of brain development. This study develops an attention-based deep learning model to predict gestational age of the fetal brain. The proposed mo…
3D CNN accurately classifies infant neurodevelopmental age from MRI scans.
problem Estimating neurodevelopmental age in infants from MRI data.
method 3D Convolutional Neural Network (3D CNN) trained on MRI images of 112 infants.
result 3D CNN achieves 99% sensitivity and 98.3% specificity in age classification.
Deep CNNs identify age-related patterns in fetal brain activity.
problem Understanding age effects in fetal brain development.
method Supervised 3D Convolutional Neural Networks applied to fetal fMRI data.
result Deep CNNs can distinguish age groups in fetal brain activity.
Machine learning models predict brain age with systematic bias, corrected in this study.
problem Systematic bias in machine learning regression models for brain age prediction.
method General constrained optimization approach to correct bias.
result Our method effectively eliminates the bias from brain age predictions.
VNNs transfer well across datasets for brain age prediction using cortical thickness features.
problem Predicting brain age using anatomical features.
method Transferability of coVariance neural networks (VNNs) in brain age prediction.
result VNNs can assign anatomical interpretability to elevated brain age gap in AD.
Unified VAE for brain aging analysis improves regression accuracy.
problem Applying VAE to supervised learning for brain imaging data.
method Unified probabilistic model for latent space learning with conditional distribution modeling.
result Model predicts age from MR images more accurately than state-of-the-art methods.
New method extracts brain age from MRI sequences over time.
problem Lack of ground-truth labels in longitudinal neuroimaging data.
method Combines factor disentanglement with self-supervised learning.
result Extracts brain age information from MRI sequences.
Local semi-supervised method improves brain tissue classification in child MRI.
problem Inaccurate detection of brain tissue classes due to intensity variations in early developing brains.
method Kernel Fisher Discriminant Analysis (KFDA) combined with SSIM for perceptual image quality assessment.
result Optimal brain partitioning into subdomains with different average intensity values and separating surfaces between brain parts.
AutoML library TPOT optimizes brain age prediction models without prior knowledge.
problem Optimizing machine learning models for brain age prediction.
method TPOT uses genetic programming to find optimal machine learning pipelines.
result TPOT outperformed state-of-the-art models in brain age prediction.
Paper analyzes shapes of brain arterial networks using statistical methods.
problem Quantifying and comparing shapes of brain arterial networks.
method Mathematical representation of BAN shapes as elastic shape graphs, development of Riemannian metrics and geometrical tools.
result Age has a clear, quantifiable effect on BAN shapes, with increased variance in shapes as age increases.
Sparse ELM classifier predicts brain ages from adolescent multimodal brain data.
problem Predicting brain ages from adolescent multimodal brain data with high accuracy.
method Sparse ELM classifier using residual errors for feature pruning.
result RES-ELM classifier outperforms conventional and sparse Bayesian learning ELM.
The paper uses distance correlation for brain connectivity and a novel multi-task learning model for age prediction.
problem Estimating age-related gender differences in brain functional connectivity.
method Estimates functional connectivity using distance correlation and proposes a non-convex multi-task learning model.
result The proposed non-convex multi-task learning model outperforms other models in age prediction and gender-specific connectivity.
Given the wide success of convolutional neural networks (CNNs) applied to natural images, researchers have begun to apply them to neuroimaging data. To date, however, exploration of novel CNN architectures tailored to neuroimaging data has been limited. Several recent works fail to leverage the 3D structure of the brai…
Proposes a new Sliced-Wasserstein distance for covariance matrices in M/EEG signals.
problem Efficiently dealing with distributions of covariance matrices in M/EEG multivariate time series.
method Defines a Sliced-Wasserstein distance for symmetric positive definite matrices and applies it to brain-age prediction and Brain Computer Interface applications.
result Demonstrates computational efficiency and strong theoretical guarantees for the proposed distance.
Generative models create synthetic MRI brain scans for research.
problem Lack of large, diverse medical datasets for machine learning.
method Training generative models on 40,000 MRI scans to produce 18,000 synthetic samples.
result Generated samples improve machine learning model accuracy.
The study explores how brain development can inspire efficient deep learning models.
problem Efficient and robust optimization procedures for deep learning.
method Inspiration from biological neural development to improve deep learning models.
result Biological neural development can inspire efficient and robust optimization procedures.
The paper predicts brain tumor patient survival using segmentation and features.
problem Predicting overall survival of brain tumor patients.
method Automated brain tumor segmentation and use of age, shape, and volumetric features for prediction.
result Random forest classifier achieves 59% accuracy on test dataset and 67% on gross total resection dataset.
BiLiNGAM model reveals brain emotion circuit development in adolescents.
problem Understanding brain emotion circuit development during adolescence.
method Bayesian incorporated linear non-Gaussian acyclic model (BiLiNGAM) for multiple DAGs estimation.
result BiLiNGAM reveals unique developmental hub structures and group-specific patterns in emotion-related intra- and inter-modular connectivity.
New methods predict brain age from MEG/EEG without source modeling.
problem Predicting brain age from MEG/EEG data without source localization.
method Two Riemannian approaches to vectorize rank-reduced covariance matrices for regression.
result Data-driven Riemannian methods outperform sensor-space estimators and biophysics models.
Sparse symmetric tensor regression reduces brain connectivity complexity.
problem Complex brain connectivity analysis in neuroimaging.
method Sparse symmetric tensor regression model for functional connectivity.
result Superior performance in Alzheimer's disease detection.
The paper generates future brain imaging sequences for Alzheimer's disease detection.
problem Understanding brain aging and neurodegenerative diseases through sequential image data.
method Formulated a min-max problem based on f-divergence to learn a time series generator using a deep neural network. result Generated image sequences converge to the latent truth under specific conditions, enhancing downstream tasks like Alzheimer's disease detection.
The paper uses neural networks to segment brain tumors and predict patient survival.
problem Brain tumor segmentation and survival prediction.
method Fully convolutional neural network with encoder-decoder architecture, radiomic features, and random forest regression.
result 55.4% classification accuracy for predicting survival of patients with gross-total resection.
Synthetic learning improves neonatal brain MRI segmentation robustness.
problem Challenges in neonatal brain MRI segmentation due to image contrast and anatomical variations.
method Synthetic learning model trained on few T2-weighted volumes, then enhanced with motion artifacts and over-segmentation.
result Synthetic learning robust to image contrast and improves segmentation of both T1- and T2-weighted images.
Stochastic encoding improves gender classification of brain networks from UK Biobank data.
problem Complexity and bias in interpreting deep learning models of brain connectivity.
method Stochastic encoding in ensemble of CNNs, multivariate balancing algorithm.
result AUROC of 0.8459, with resting-state data more accurate than task data.
ICAM creates interpretable feature attribution maps for brain images.
problem Challenges in predicting class relevance from brain images due to heterogeneity and background variation.
method A VAE-GAN framework for disentangling class relevance from background features.
result FA maps generated by ICAM outperform baseline methods and support phenotype variation exploration.
This paper describes a new neuroimaging analysis toolbox that allows for the modeling of nonlinear effects at the voxel level, overcoming limitations of methods based on linear models like the GLM. We illustrate its features using a relevant example in which distinct nonlinear trajectories of Alzheimer's disease relate…
ST-GCN improves rs-fMRI prediction accuracy by modeling spatio-temporal graph connectivity.
problem Existing rs-fMRI methods neglect functional connectivity or temporal dynamics.
method Spatio-temporal graph convolutional network (ST-GCN) trained on BOLD time series.
result ST-GCN predicts gender and age more accurately than common methods.
Neural network predicts intelligence from brain structure measurements.
problem Predicting intelligence scores from brain structure measurements.
method Four-layer fully-connected neural network (FNN) using volumes, WM/GM contrast, and cortical thickness.
result Achieved MSE of 94.0270 in test set.
New methods compare neural network models using geometric and topological summaries.
problem Comparing deep representations of complex networks in models and brains.
method Develops inference methods based on topological data analysis (TDA) and graph-based techniques.
result New statistical methods enable better model comparison and inference.
MRI image quality affects statistical and predictive analysis of brain morphology.
problem Impact of MRI image quality on statistical and predictive analysis of brain morphology.
method Systematic testing of image quality on univariate statistics and machine learning classification using three large datasets.
result Low-quality MRI data significantly affects detecting significant sex/gender differences in smaller samples, but not in larger ones.
We describe a new method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on multidimensional classification of hippocampal shape features. This approach uses spherical harmonics (SPHARM) coefficients to model the shape of the hi…
New method identifies causal brain connections from fMRI data.
problem Identifying causal brain interactions from statistical associations.
method ψ-learning incorporated linear non-Gaussian acyclic model (ψ-LiNGAM). result Identified three types of hub structures and 16 causal flows.
Visualizes ConvNets without confounding effects.
problem Misinterpretation of saliency maps due to confounding variables.
method Univariate statistical tests and partial back-propagation to remove confounding effects.
result Visualization of confounder-free saliency maps.
Extends multivariate regression for tensor-variate data, identifying brain regions and facial characteristics.
problem Challenges in fitting regression models with multivariate responses and covariates.
method Low-rank tensor formats on regression coefficients and tensor-variate normal distribution for errors.
result Maximum likelihood estimators for tensor-on-tensor regression via block-relaxation algorithms.
Method converts age labels into distributions to improve speaker age estimation.
problem Label ambiguity in age labels makes precise speaker age estimation challenging.
method Converts age labels into label distributions and uses label distribution learning.
result Our method outperforms baseline methods by reducing MAE by 10% on a real-world dataset.
BSD is a Bayesian framework for analyzing neural spectral data.
problem Challenges in statistical analysis and group-level comparisons of neural power spectra.
method Bayesian Spectral Decomposition (BSD) for parametric models of neural spectra.
result BSD outperforms existing methods in model selection and parameter estimation.
Despite the remarkable progress in face recognition related technologies, reliably recognizing faces across ages still remains a big challenge. The appearance of a human face changes substantially over time, resulting in significant intra-class variations. As opposed to current techniques for age-invariant face recogni…
We solve a lifecycle model in which the consumer's chronological age does not move in lockstep with calendar time. Instead, biological age increases at a stochastic non-linear rate in time like a broken clock that might occasionally move backwards. In other words, biological age could actually decline. Our paper is ins…
The paper uses AI to analyze ECG data, revealing age-related changes and identifying key features.
problem Investigating age-related changes in ECG data to distinguish healthy from disease-related changes.
method Employed deep-learning and tree-based models on raw ECG signals and features from a diverse age group.
result Identified age-related declines in breathing rates and high SDANN values in elderly individuals.
Improved CNNs detect Alzheimer's with 14% accuracy boost.
problem Early detection of Alzheimer's Disease using MRI scans.
method Optimized 3D CNNs with instance normalization, spatial downsampling, model widening, and age information.
result 14% increase in test accuracy distinguishing AD, MCI, and controls.
Associating genetic markers with a multidimensional phenotype is an important yet challenging problem. In this work, we establish the equivalence between two popular methods: kernel-machine regression (KMR), and kernel distance covariance (KDC). KMR is a semiparametric regression frameworks that models the covariate ef…
Bayesian CNN estimates uncertainty in bone age prediction.
problem Uncertainty quantification in age estimation models.
method Variational Inference for Bayesian CNNs.
result Model uncertainty distinguished from data uncertainty.
Improved sex and age-specific model for Parkinson's diagnosis.
problem Accurate diagnosis of Parkinson's disease for better patient care.
method Sex-specific and age-dependent handwriting classification model.
result Significantly improved accuracy (83.75% for females, 79.55% for older age group) compared to generalized model.
Develops a method to analyze SARS-CoV-2 viral load vs. age, finding a significant increase.
problem Determining if SARS-CoV-2 viral load depends on patient age.
method Flexible, non-parametric, hierarchical, Bayesian, causal model.
result Statistically significant increase in viral load with age, but only for one dataset.
Paper introduces MSA for weakly supervised covariance alignment in MEG signals.
problem Limited labeled signals in target datasets for MEG applications.
method Mixing model Stiefel Adaptation (MSA) leveraging unlabeled data.
result MSA outperforms recent methods in brain-age regression with MEG signals.