New learning algorithm mimics biological neural networks.
arXiv research
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Biological networks are a very convenient modelling and visualisation tool to discover knowledge from modern high-throughput genomics and postgenomics data sets. Indeed, biological entities are not isolated, but are components of complex multi-level systems. We go one step further and advocate for the consideration of …
Proposes a novel network-based neighborhood regression for biological systems.
New learning rules for wide neural networks without backpropagation.
DeepSIBA predicts biological effects of chemical structures using graph neural networks.
Graph auto-encoder predicts unobserved node features from biological networks and omics data.
The interplay between inter-neuronal network topology and cognition has been studied deeply by connectomics researchers and network scientists, which is crucial towards understanding the remarkable efficacy of biological neural networks. Curiously, the deep learning revolution that revived neural networks has not paid …
Oja's rule improves neural network training without engineered tricks.
Fault-tolerant neural networks inspired by biological error correction codes.
Biological neural network mimics CCA for multi-channel data.
We introduce bio-inspired artificial neural networks consisting of neurons that are additionally characterized by spatial positions. To simulate properties of biological systems we add the costs penalizing long connections and the proximity of neurons in a two-dimensional space. Our experiments show that in the case wh…
In this work, we perform an exploratory study on synthesizing deep neural networks using biological synaptic strength distributions, and the potential influence of different distributions on modelling performance particularly for the scenario associated with small data sets. Surprisingly, a CNN with convolutional layer…
Training deep neural networks with the error backpropagation algorithm is considered implausible from a biological perspective. Numerous recent publications suggest elaborate models for biologically plausible variants of deep learning, typically defining success as reaching around 98% test accuracy on the MNIST data se…
Derives a biologically plausible neural network for Slow Feature Analysis.
Quantitatively predicting phenotype variables by the expression changes in a set of candidate genes is of great interest in molecular biology but it is also a challenging task for several reasons. First, the collected biological observations might be heterogeneous and correspond to different biological mechanisms. Seco…
New learning rules from information bottleneck improve deep learning without precise labels.
Deep neural networks (DNNs) transform stimuli across multiple processing stages to produce representations that can be used to solve complex tasks, such as object recognition in images. However, a full understanding of how they achieve this remains elusive. The complexity of biological neural networks substantially exc…
AR algorithm simplifies backpropagation with improved scalability and biological plausibility.
New algorithm shows neural networks can learn without full backpropagation.
Stochastic RNNs classify biological neural network paths with robust error bounds.
Develops DSD for analyzing multiscale biological networks.
Neural network models of early sensory processing typically reduce the dimensionality of streaming input data. Such networks learn the principal subspace, in the sense of principal component analysis (PCA), by adjusting synaptic weights according to activity-dependent learning rules. When derived from a principled cost…
GAIT-prop derives a biologically plausible learning rule from backpropagation.
Understanding biological network dynamics is a fundamental issue in various scientific and engineering fields. Network theory is capable of revealing the relationship between elements and their propagation; however, for complex collective motions, the network properties often transiently and complexly change. A fundame…
Sparse neural networks visualize paired transcriptomic and electrophysiological data.
TNDE quantifies dynamic gene drivers from single-cell snapshots.
Identifying latent structure in large data matrices is essential for exploring biological processes. Here, we consider recovering gene co-expression networks from gene expression data, where each network encodes relationships between genes that are locally co-regulated by shared biological mechanisms. To do this, we de…
Networks are ubiquitous in biology and computational approaches have been largely investigated for their inference. In particular, supervised machine learning methods can be used to complete a partially known network by integrating various measurements. Two main supervised frameworks have been proposed: the local appro…
engGNN combines external and generated graphs to improve disease classification and biomarker discovery.
New algorithm for online training of Spiking Neural Networks (SNNs).
A new theory explains large associative memory with biological plausibility.
In real world scenarios, objects are often partially occluded. This requires a robustness for object recognition against these perturbations. Convolutional networks have shown good performances in classification tasks. The learned convolutional filters seem similar to receptive fields of simple cells found in the prima…
Deep neural networks (DNNs) are known for extracting useful information from large amounts of data. However, the representations learned in DNNs are typically hard to interpret, especially in dense layers. One crucial issue of the classical DNN model such as multilayer perceptron (MLP) is that neurons in the same layer…
New method identifies key genes affecting phenotypes in biological systems.
The power law has been observed in the degree distributions of many biological neural networks. Sparse deep neural networks, which learn an economical representation from the data, resemble biological neural networks in many ways. In this paper, we study if these artificial networks also exhibit properties of the power…
Finding biologically plausible alternatives to back-propagation of errors is a fundamentally important challenge in artificial neural network research. In this paper, we propose a learning algorithm called error-driven Local Representation Alignment (LRA-E), which has strong connections to predictive coding, a theory t…
DASH simplifies neural networks for gene regulatory dynamics using domain knowledge.
This paper explores adaptive neural activation in RNNs for better learning.
Defines metrics to compare neural network representations.
One conjecture in both deep learning and classical connectionist viewpoint is that the biological brain implements certain kinds of deep networks as its back-end. However, to our knowledge, a detailed correspondence has not yet been set up, which is important if we want to bridge between neuroscience and machine learni…
Log-Normal Multiplicative Dynamics improves low-precision training of neural networks.
A new model for sequential memory using temporal predictive coding.
Recent technological advancements in data acquisition tools allowed life scientists to acquire multimodal data from different biological application domains. Broadly categorized in three types (i.e., sequences, images, and signals), these data are huge in amount and complex in nature. Mining such an enormous amount of …
Biological data including gene expression data are generally high-dimensional and require efficient, generalizable, and scalable machine-learning methods to discover their complex nonlinear patterns. The recent advances in machine learning can be attributed to deep neural networks (DNNs), which excel in various tasks i…
In the past few years, deep learning has transformed artificial intelligence research and led to impressive performance in various difficult tasks. However, it is still unclear how the brain can perform credit assignment across many areas as efficiently as backpropagation does in deep neural networks. In this paper, we…
Error backpropagation is a highly effective mechanism for learning high-quality hierarchical features in deep networks. Updating the features or weights in one layer, however, requires waiting for the propagation of error signals from higher layers. Learning using delayed and non-local errors makes it hard to reconcile…
Proposes a new neural network architecture inspired by biology to improve learning and information flow.
`Biologically inspired' activation functions, such as the logistic sigmoid, have been instrumental in the historical advancement of machine learning. However in the field of deep learning, they have been largely displaced by rectified linear units (ReLU) or similar functions, such as its exponential linear unit (ELU) v…