Financial fraud detection in digital banking requires reasoning over multiple heterogeneous event streams.
problem Financial fraud detection in digital banking requires reasoning over multiple heterogeneous event streams.
method Multi-Stream Fraud Transformer (MSFT) architecture that encodes each event stream with independent Transformer encoders and fuses their representations through configurable mechanisms.
result Sequence models significantly outperform gradient-boosted trees operating on aggregated features.
New method uses KL divergence to detect out-of-distribution data effectively.
problem Flow-based models assign higher likelihoods to OOD data than ID data, making OOD detection challenging.
method Proposes a method leveraging KL divergence and local pixel dependence of representations for anomaly detection.
result Demonstrates effectiveness and robustness on prevalent benchmarks.
LxCIM metric improves binary classification performance evaluation.
problem Evaluation metrics for binary classification are often not invariant to local class exchange.
method Proposes LxCIM, a rank-based metric invariant to local class exchange.
result LxCIM addresses limitations of existing metrics like AUROC.
When training clinical prediction models from electronic health records (EHRs), a key concern should be a model's ability to sustain performance over time when deployed, even as care practices, database systems, and population demographics evolve. Due to de-identification requirements, however, current experimental pra…
Recently, researchers have started applying convolutional neural networks (CNNs) with one-dimensional convolutions to clinical tasks involving time-series data. This is due, in part, to their computational efficiency, relative to recurrent neural networks and their ability to efficiently exploit certain temporal invari…
Objective: The advent of Electronic Medical Records (EMR) with large electronic imaging databases along with advances in deep neural networks with machine learning has provided a unique opportunity to achieve milestones in automated image analysis. Optical coherence tomography (OCT) is the most commonly obtained imagin…
FeDXL tackles federated learning for X-risk optimization.
problem Optimizing a family of X-risks with federated learning, where existing algorithms are not applicable.
method Active-passive decomposition framework, federated averaging and merging, novel theoretical analysis.
result FeDXL algorithms for linear and nonlinear f are developed, with established complexities and improved performance. Model predicts cognitive health risks based on smartphone usage patterns.
problem Identifying cognitive health risks through smartphone usage.
method Structured models of smartphone interactions analyzed over 12 weeks.
result AUROC of 0.79 in discriminating between healthy and symptomatic subjects.
In healthcare, patient risk stratification models are often learned using time-series data extracted from electronic health records. When extracting data for a clinical prediction task, several formulations exist, depending on how one chooses the time of prediction and the prediction horizon. In this paper, we show how…
Study assesses CNN model robustness to noise in low-cost CT scans.
problem Evaluate CNN model performance on noisy, artifact-prone low-cost CT images.
method Developed and tested a CNN model for head CT triage, varying tube current and projections.
result Model remains robust to reduced tube current and fewer projections, maintaining AUROC close to original.
In this work, a dense recurrent convolutional neural network (DRCNN) was constructed to detect sleep disorders including arousal, apnea and hypopnea using Polysomnography (PSG) measurement channels provided in the 2018 Physionet challenge database. Our model structure is composed of multiple dense convolutional units (…
Machine learning detects NASH patients from medical claims data.
problem Detecting undiagnosed NASH patients for screening and management.
method Gradient-boosted decision trees trained on administrative medical claims data.
result Model precision for NASH detection is significantly higher than NASH incidence.
Study predicts startup outcomes like funding, patenting, IPOs using machine learning.
problem Forecasting startup success metrics like funding, patenting, IPOs.
method Developed interpretable machine learning framework, used preprocessing, class imbalance handling, and compared multiple models.
result Achieved high AUROC values for patent, funding, and exit predictions.
Sepsis is the leading cause of death in non-coronary intensive care units. Moreover, a delay of antibiotic treatment of patients with severe sepsis by only few hours is associated with increased mortality. This insight makes accurate models for early prediction of sepsis a key task in machine learning for healthcare. P…
New research shows non-bottlenecked autoencoders can outperform bottlenecked ones for anomaly detection.
problem The necessity of a bottleneck in autoencoders for anomaly detection.
method Investigated two ways to remove bottlenecks: overparameterising the latent layer and introducing skip connections. Carried out extensive experiments on various AE types and datasets.
result Non-bottlenecked autoencoders can outperform bottlenecked ones, improving anomaly detection performance.
Deep learning predicts readmissions from less structured data.
problem Predicting readmissions from non-standard, unstructured medical records.
method Proposes a deep learning architecture that handles less structured data, including Spanish text.
result Achieves AUROC of 0.76 on a Chilean medical dataset, comparable to US results.
Optimizes one-class classification methods for better performance.
problem Improving one-class classification accuracy through hyperparameter optimization.
method Hyperparameter optimization for five one-class classification methods (SVM, NND, LNND, LOF, ALP) using various datasets.
result ALP and SVM perform best after hyperparameter optimization, with ALP being more efficient.
Longitudinal patient data has the potential to improve clinical risk stratification models for disease. However, chronic diseases that progress slowly over time are often heterogeneous in their clinical presentation. Patients may progress through disease stages at varying rates. This leads to pathophysiological misalig…
With a mortality rate of 5.4 million lives worldwide every year and a healthcare cost of more than 16 billion dollars in the USA alone, sepsis is one of the leading causes of hospital mortality and an increasing concern in the ageing western world. Recently, medical and technological advances have helped re-define the …
CPR models complex decision processes by breaking them into context-specific policies, improving interpretability and accuracy.
problem Interpreting dynamic human decision-making processes in medical contexts.
method Develops Contextualized Policy Recovery (CPR) framework for multi-task learning, modeling each context-specific policy as a linear map.
result Achieves state-of-the-art performance in predicting medical decisions, closing the gap between interpretable and black-box methods.
New framework for optimizing machine learning risks.
problem Optimizing non-decomposable machine learning objectives.
method Empirical X-risk minimization (EXM) framework with algorithmic techniques.
result Developed algorithms for solving EXM with smooth non-convex objectives.
Machine-learning algorithms have gained popularity in recent years in the field of ecological modeling due to their promising results in predictive performance of classification problems. While the application of such algorithms has been highly simplified in the last years due to their well-documented integration in co…
Although timely sepsis diagnosis and prompt interventions in Intensive Care Unit (ICU) patients are associated with reduced mortality, early clinical recognition is frequently impeded by non-specific signs of infection and failure to detect signs of sepsis-induced organ dysfunction in a constellation of dynamically cha…
The timeliness of detection of a sepsis event in progress is a crucial factor in the outcome for the patient. Machine learning models built from data in electronic health records can be used as an effective tool for improving this timeliness, but so far the potential for clinical implementations has been largely limite…
We present two deep generative models based on Variational Autoencoders to improve the accuracy of drug response prediction. Our models, Perturbation Variational Autoencoder and its semi-supervised extension, Drug Response Variational Autoencoder (Dr.VAE), learn latent representation of the underlying gene states befor…
Random forest models predict CLABSI risk in hospital admissions, with static models performing similarly to dynamic ones.
problem Predicting CLABSI risk in hospital admissions using EHR data with competing risks.
method Comparison of static and dynamic random forest models for binary, multinomial, survival, and competing risks outcomes.
result Static and dynamic random forest models perform similarly in predicting CLABSI risk, with multinomial models having the lowest computation times.
Natural language processing improves COVID-19 hospitalization identification.
problem Identifying patients hospitalized due to COVID-19 among those with positive SARS-CoV-2 tests.
method Used natural language processing on provider notes and structured EHR data elements to create classification algorithms.
result Classification algorithms using provider notes outperformed those using only structured EHR data elements, with AUROC of 0.894 compared to 0.841.
Identifying patients who will be discharged within 24 hours can improve hospital resource management and quality of care. We studied this problem using eight years of Electronic Health Records (EHR) data from Stanford Hospital. We fit models to predict 24 hour discharge across the entire inpatient population. The best …
Donor-aware scRNA-seq benchmarks improve classification accuracy in inflammatory bowel disease.
problem Influenza disease classification from scRNA-seq data is prone to donor-level confounding.
method Developed and evaluated three feature representations across two IBD cohorts.
result Compartment-stratified CLR composition and GatedStructuralCFN embeddings outperform linear models in classification accuracy.
Temporal Causal Prior-Data Fitted Networks (TCPFN) for industrial time series causal discovery
problem Estimating causal effects in industrial time series
method Temporal Causal Prior-Data Fitted Networks
result Zero-shot causal discovery with explicit reliability signals
Massively multi-label prediction/classification problems arise in environments like health-care or biology where very precise predictions are useful. One challenge with massively multi-label problems is that there is often a long-tailed frequency distribution for the labels, which results in few positive examples for t…
FraudTransformer detects payment fraud by preserving event order and time gaps.
problem Detecting payment fraud in real-world banking streams with irregular time gaps.
method Augments a GPT-style architecture with a dedicated time encoder and a learned positional encoder.
result FraudTransformer outperforms classical and transformer baselines, achieving highest AUROC and PRAUC on held-out test set.
Paper decomposes risk into aleatoric and epistemic uncertainties and generates predictive uncertainty measures.
problem Unclear relationships between various predictive uncertainty measures in literature.
method Bayesian estimation to decompose risk into aleatoric and epistemic uncertainties, generating different predictive uncertainty measures.
result Experimental validation confirms usefulness of derived predictive uncertainty measures for detecting out-of-distribution and misclassified instances.
Sleep disorders are implicated in a growing number of health problems. In this paper, we present a signal-processing/machine learning approach to detecting arousals in the multi-channel polysomnographic recordings of the Physionet/CinC Challenge2018 dataset. Methods: Our network architecture consists of two components.…
GRU-D detects age-specific missing patterns in vital signs.
problem Temporal missingness in clinical time series data.
method Gated recurrent unit with decay mechanisms (GRU-D) trained on MIMIC-IV vital signs.
result GRU-D achieves AUROC 0.780 and AUPRC 0.810 on bootstrapped data.
Our work focuses on the problem of predicting the transfer of pediatric patients from the general ward of a hospital to the pediatric intensive care unit. Using data collected over 5.5 years from the electronic health records of two medical facilities, we develop classifiers based on adaptive boosting and gradient tree…
ISAAC audits deep models for drug-target interactions, revealing structural differences.
problem Deep models for DTI often use irrelevant features, making them hard to evaluate.
method ISAAC uses intervention-based structural auditing to evaluate model sensitivity.
result ISAAC reveals significant structural differences in DTI models' reasoning.
Logistic regression (LR) is widely used in clinical prediction because it is simple to deploy and easy to interpret. Nevertheless, being a linear model, LR has limited expressive capability and often has unsatisfactory performance. Generalized additive models (GAMs) extend the linear model with transformations of input…
Language models improve clinical prediction models using EHR data.
problem Limited patient data for training clinical prediction models.
method Using patient representation schemes from natural language processing.
result 3.5% mean improvement in AUROC on five prediction tasks.
Hypertension is a major risk factor for stroke, cardiovascular disease, and end-stage renal disease, and its prevalence is expected to rise dramatically. Effective hypertension management is thus critical. A particular priority is decreasing the incidence of uncontrolled hypertension. Early identification of patients a…
Study finds AI can predict diverse cardiac and non-cardiac diagnoses from a single ECG.
problem Narrow focus of ECG analysis models for diverse medical conditions.
method Exploratory study using a single AI model to predict multiple ICD codes.
result Model achieved AUROC scores > 0.8 for 253 cardiac and 172 non-cardiac diagnoses.
Dynamic assessment of patient status (e.g. by an automated, continuously updated assessment of outcome) in the Intensive Care Unit (ICU) is of paramount importance for early alerting, decision support and resource allocation. Extraction and cleaning of expert-selected clinical variables discards information and protrac…
Paper defends diffusion models from membership inference attacks using Langevin dynamics.
problem Defending diffusion models against membership inference attacks.
method Uses critically-damped higher-order Langevin dynamics with auxiliary variables.
result Demonstrates improved resistance to membership inference attacks through theoretical investigation and validation.
A new method uses adversarial attacks to detect other adversarial attacks.
problem Detecting iterative adversarial attacks on deep neural networks.
method Using the Carlini-Wagner (CW) attack as a detector itself, under certain assumptions.
result The method provides asymptotically optimal separation of original and attacked images.
Contrastive Code Representation Learning improves code summarization and type inference.
problem Code representations are sensitive to edits, hindering downstream semantic understanding tasks.
method ContraCode: a contrastive pre-training task that learns code functionality.
result Contrastive pre-training improves code summarization and type inference accuracy.
Deep neural network predicts diabetic readmission with high accuracy.
problem Predicting 30-day readmission for diabetic patients.
method Categorical embeddings and deep neural network.
result 95.2% accuracy and 97.4% AUROC on diabetic readmission data.
Signaling proteins are an important topic in drug development due to the increased importance of finding fast, accurate and cheap methods to evaluate new molecular targets involved in specific diseases. The complexity of the protein structure hinders the direct association of the signaling activity with the molecular s…
The UN Sustainable Development Goals allude to the importance of infrastructure quality in three of its seventeen goals. However, monitoring infrastructure quality in developing regions remains prohibitively expensive and impedes efforts to measure progress toward these goals. To this end, we investigate the use of wid…