A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.
We present a nonparametric Bayesian method for disease subtype discovery in multi-dimensional cancer data. Our method can simultaneously analyse a wide range of data types, allowing for both agreement and disagreement between their underlying clustering structure. It includes feature selection and infers the most likel…
KLIC combines multiple datasets for clustering, down-weighting noisy data.
In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal, tumour classification and post-operative survival. Attempts are made to learn re…
Deep learning model explains breast cancer subtypes using logistic regression.
Microwave-based breast cancer detection has been proposed as a complementary approach to compensate for some drawbacks of existing breast cancer detection techniques. Among the existing microwave breast cancer detection methods, machine learning-type algorithms have recently become more popular. These focus on detectin…
New method clusters disease subtypes from model explanations.
Study identifies five AD subtypes using graph diffusion and similarity learning.
Study proposes a model to improve patient subtyping from EHR data.
Improved detection of brain tumours in MRIs using latent space dissimilarities.
We release a large ECG dataset for arrhythmia subtype discovery.
Patient subtyping based on temporal observations can lead to significantly nuanced subtyping that acknowledges the dynamic characteristics of diseases. Existing methods for subtyping trajectories treat the evolution of clinical observations as a homogeneous process or employ data available at regular intervals. In real…
While developing their software, professional object-oriented (OO) software developers keep in their minds an image of the subtyping relation between types in their software. The goal of this paper is to present an observation about the graph of the subtyping relation in Java, namely the observation that, after the add…
Unsupervised method selects genes for tumor subtype discovery.
In many applications, multivariate samples may harbor previously unrecognized heterogeneity at the level of conditional independence or network structure. For example, in cancer biology, disease subtypes may differ with respect to subtype-specific interplay between molecular components. Then, both subtype discovery and…
Due to the complexity of cancer, clustering algorithms have been used to disentangle the observed heterogeneity and identify cancer subtypes that can be treated specifically. While kernel based clustering approaches allow the use of more than one input matrix, which is an important factor when considering a multidimens…
Alzheimer's disease (AD) is a degenerative brain disease impairing a person's ability to perform day to day activities. The clinical manifestations of Alzheimer's disease are characterized by heterogeneity in age, disease span, progression rate, impairment of memory and cognitive abilities. Due to these variabilities, …
Bayesian model clusters diverse 'omics data for disease subtyping.
Bayesian variational inference improves medical image segmentation confidence.
MAGIC uncovers disease heterogeneity across brain scales.
New framework distinguishes lung cancer subtypes using MALDI mass spectrometry.
Smile-GANs clusters brain MRI scans to reveal disease subtypes and progression.
Study assesses linear classifiers for virus genotyping and subtyping.
A benchmark evaluates ioUS-to-MR synthesis methods for brain tumor surgery.
StageNet improves health risk prediction by integrating disease stage information.
Personalized treatment of patients based on tissue-specific cancer subtypes has strongly increased the efficacy of the chosen therapies. Even though the amount of data measured for cancer patients has increased over the last years, most cancer subtypes are still diagnosed based on individual data sources (e.g. gene exp…
Proposes a new clustering algorithm for high-dimensional data.
Improved likelihood-free inference using preconditioned neural posterior estimation.
Model learns to select relevant clinical variables for disease subtype prediction from small data.
Bioinformatics tools have been developed to interpret gene expression data at the gene set level, and these gene set based analyses improve the biologists' capability to discover functional relevance of their experiment design. While elucidating gene set individually, inter gene sets association is rarely taken into co…
Paper proposes clustering model for ICC based on histologic patterns.
Cluster analysis aims at separating patients into phenotypically heterogenous groups and defining therapeutically homogeneous patient subclasses. It is an important approach in data-driven disease classification and subtyping. Acute coronary syndrome (ACS) is a syndrome due to sudden decrease of coronary artery blood f…
UCSL combines clustering with supervised learning to discover interpretable subtypes.
More than two thirds of mental health problems have their onset during childhood or adolescence. Identifying children at risk for mental illness later in life and predicting the type of illness is not easy. We set out to develop a platform to define subtypes of childhood social-emotional development using longitudinal,…
Machine learning improves glioma diagnosis and prognosis.
The ability to accurately classify disease subtypes is of vital importance, especially in oncology where this capability could have a life saving impact. Here we report a classification between two subtypes of non-small cell lung cancer, namely Adeno- carcinoma vs Squamous cell carcinoma. The data consists of approxima…
We investigate the use of self-tracking data and unsupervised mixed-membership models to phenotype endometriosis. Endometriosis is a systemic, chronic condition of women in reproductive age and, at the same time, a highly enigmatic condition with no known biomarkers to monitor its progression and no established staging…
Precision medicine aims for personalized prognosis and therapeutics by utilizing recent genome-scale high-throughput profiling techniques, including next-generation sequencing (NGS). However, translating NGS data faces several challenges. First, NGS count data are often overdispersed, requiring appropriate modeling. Se…
Study examines XAI methods for ECG analysis to improve model transparency.
The rapid development of high-throughput technologies has enabled the generation of data from biological or disease processes that span multiple layers, like genomic, proteomic or metabolomic data, and further pertain to multiple sources, like disease subtypes or experimental conditions. In this work, we propose a gene…
Clustering analysis is one of the most widely used statistical tools in many emerging areas such as microarray data analysis. For microarray and other high-dimensional data, the presence of many noise variables may mask underlying clustering structures. Hence removing noise variables via variable selection is necessary…
VICatMix clusters categorical biomedical data efficiently and selects relevant variables.
The study finds obstructions for certain Weyl curvature tensors on manifolds.
Multi-view data, that is matched sets of measurements on the same subjects, have become increasingly common with advances in multi-omics technology. Often, it is of interest to find associations between the views that are related to the intrinsic class memberships. Existing association methods cannot directly incorpora…
We consider the problem of jointly estimating multiple inverse covariance matrices from high-dimensional data consisting of distinct classes. An -penalized maximum likelihood approach is employed. The suggested approach is flexible and generic, incorporating several other -penalized estimators as specia…
Modeling disease progression using irregular time intervals in EHRs.
OPAL optimizes labeling strategy for precise inference from uncertain models.
Retina-VAE models macular disease spectrum using clinical data.
The study examines Cox models for lifetime loan default risk, addressing biased estimates by incorporating recurrent events.