Marginal structural models (MSMs) estimate the causal effect of a time-varying treatment in the presence of time-dependent confounding via weighted regression. The standard approach of using inverse probability of treatment weighting (IPTW) can lead to high-variance estimates due to extreme weights and be sensitive to …
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48 results for “time-dependent confounding”
Develops a deep survival model for causal inference in longitudinal studies.
problem Estimating treatment effects on time-to-event outcomes in observational studies with time-dependent covariates.
method TCS model using potential outcomes framework and ensemble of recurrent subnetworks.
result Identifies conditional average treatment effects and individual treatment effect heterogeneity over time.
CDM models counterfactual outcomes in longitudinal data with improved accuracy.
problem Predicting counterfactual outcomes in longitudinal data with complex time-dependent confounding.
method Causal Diffusion Model (CDM) using denoising diffusion architecture with relational self-attention.
result CDM outperforms state-of-the-art methods in generating full probabilistic distributions of counterfactual outcomes.
Developed a flexible Bayesian g-formula for causal survival analysis with time-dependent confounding.
problem Estimating causal survival curves in longitudinal observational studies with time-varying treatments and confounding.
method Incorporated Bayesian Additive Regression Trees (BART) into the g-formula to model time-evolving generative components and mitigate bias due to model misspecification.
result Demonstrated improved empirical performance and practical utility of the proposed method through simulations and real-world data analysis.
Dynamic Structural Causal Models handle time-dependent systems with cycles and latent confounding.
problem Representing and analyzing systems of Stochastic Differential Equations (SDEs) with DSCMs.
method Define time-splitting and subsampling operations to analyze DSCMs of SDEs, and apply existing causal discovery algorithms to time-series data.
result DSCMs provide a graphical Markov property for SDEs and enable identification of time-dependent causal effects.
Paper develops a new estimator for dynamic treatment effects in high-dimensional settings.
problem Time-varying confounding and model misspecification in estimating dynamic treatment effects.
method Sequential model doubly robust estimator with moment-targeting estimates.
result Root-N inference achieved under model misspecification, even with high-dimensional covariates.
Identifying when to give treatments to patients and how to select among multiple treatments over time are important medical problems with a few existing solutions. In this paper, we introduce the Counterfactual Recurrent Network (CRN), a novel sequence-to-sequence model that leverages the increasingly available patient…
Deep Bayesian models estimate causal effects for dynamic treatment regimes over long follow-up times.
problem Challenges in causal effect estimation for dynamic treatment regimes with long follow-up times.
method Combining outcome regression models with deep Bayesian models for high-dimensional features.
result Stable and accurate dynamic causal effect estimation from observational data, especially with long-term follow-up.
The paper proposes a method to precisely decompose confounders and estimate treatment effects.
problem Estimating treatment effects from observational data with confounder identification and balancing.
method Learning decomposed representations to identify and balance confounders and non-confounders.
result The method achieves more precise treatment effect estimation than existing methods.
Research shows continual learning challenges in confounded datasets.
problem Challenges in mitigating confounders in continual learning settings.
method Formal description of continual confounders, construction of ConCon dataset.
result Standard continual learning methods fail to ignore confounders.
Statistical learning on biological data can be challenging due to confounding variables in sample collection and processing. Confounders can cause models to generalize poorly and result in inaccurate prediction performance metrics if models are not validated thoroughly. In this paper, we propose methods to control for …
Causal inference from observational data requires assumptions. These assumptions range from measuring confounders to identifying instruments. Traditionally, causal inference assumptions have focused on estimation of effects for a single treatment. In this work, we construct techniques for estimation with multiple treat…
Detect hidden confounding in observational data using multiple environments.
problem Detect hidden confounding in observational data.
method Theoretical framework and simulation studies to test for hidden confounding.
result The proposed procedure correctly predicts hidden confounding, especially when bias is large.
Machine learning confound removal biases results, leading to misleading predictions.
problem Common confound removal methods in machine learning lead to misleading predictions.
method Featurewise removal of confound variance by linear regression before applying ML.
result This common deconfounding approach can leak information, amplifying null or moderate effects.
KRCD detects unobserved confounders in nonlinear observational data.
problem Detecting unobserved confounders in nonlinear observational studies.
method Kernel Regression Confounder Detection (KRCD) using reproducing kernel Hilbert spaces.
result KRCD outperforms existing methods and achieves superior computational efficiency.
Study identifies conditions for proxy adjustment in confounded binary treatment outcomes.
problem Average causal effect estimation with a non-differentially mismeasured binary confounder.
method Identifies conditions for proxy adjustment in the presence of a non-differentially mismeasured binary confounder.
result Adjusting for a non-differentially mismeasured binary proxy can improve estimation of the average causal effect.
New method estimates policy performance under unobserved confounding.
problem Estimating policy performance when decisions depend on unobserved variables.
method Developed worst-case bounds for robust OPE under unobserved confounding.
result Efficient procedure for computing worst-case bounds, proving statistical consistency.
Consistent estimator derived for confounding strength in observational data.
problem Estimating confounding strength in observational data is challenging due to unobserved confounders.
method Derived and adapted a consistent estimator using tools from random matrix theory.
result The original estimator is not consistent, but an adapted one is.
A new method uses randomized trials to estimate the strength of unobserved confounding.
problem Unobserved confounding compromises causal conclusions from non-randomized studies.
method Designs a statistical test to detect unobserved confounding strength and estimates a lower bound.
result Estimates an asymptotically valid lower bound on unobserved confounding strength.
This paper tackles confounding biases in data augmentation.
problem Mitigating spurious correlations and confounding variables in training data.
method Formal analysis and counterfactual data augmentation.
result Removing confounding biases leads to invariant features and better generalization.
New method recovers latent confounders from high-dimensional proxy variables.
problem Detecting latent confounders from high-dimensional proxy variables.
method Proxy Confounder Factorization (PCF) framework using ICA-PCF and GD-PCF.
result ICA-PCF recovers confounders with high correlation and low error in synthetic and real-world data.
Proposes tests to control confounding bias in predictive models.
problem Lack of non-parametric tests for confounding bias in predictive modeling.
method Partial and full confounder tests for probing null hypotheses of unconfounded and fully confounded models.
result Reveals previously unreported or hard-to-correct confounders in machine learning models.
New method tackles confounded bandit problems with dual instrumental variables.
problem Confounded contextual bandit problems where noise affects both contexts and rewards.
method Dual instrumental variable regression applied to reproducing kernel Hilbert spaces.
result Near-optimal convergence rate and computationally efficient algorithms proved.
Study of time-dependent metrics and connections in geometry.
problem Understanding geodesics and connections in time-dependent Riemannian manifolds.
method Examine connections on product manifolds, explore parallel transport, geodesics, and torsion.
result Define the derivative of a one-parameter family of connections.
New approach for causal inference with interdependent, time-varying latent confounders.
problem Estimating causal effects with interdependent, time-varying latent confounders.
method Variational estimation with a representer theorem and random input space.
result Demonstrates effectiveness on various temporal datasets.
Causal discovery from data affected by latent confounders is an important and difficult challenge. Causal functional model-based approaches have not been used to present variables whose relationships are affected by latent confounders, while some constraint-based methods can present them. This paper proposes a causal f…
Estimating the individual treatment effect (ITE) from observational data is essential in medicine. A central challenge in estimating the ITE is handling confounders, which are factors that affect both an intervention and its outcome. Most previous work relies on the unconfoundedness assumption, which posits that all th…
CARE improves LLM aggregation by accounting for shared confounders.
problem LLM judges' correlated errors due to shared latent confounders.
method CARE explicitly models judges' scores as true quality and confounders.
result CARE reduces aggregation error by up to 26.8% across various benchmarks.
Proposes BDCM to handle unmeasured confounders in causal inference.
problem Handling unmeasured confounders in causal inference.
method Backdoor criterion to find variables for diffusion model.
result Captures counterfactual distribution more precisely.
Hierarchically-coupled hidden Markov models for learning kinetic rates from single-molecule datastat.ML
We address the problem of analyzing sets of noisy time-varying signals that all report on the same process but confound straightforward analyses due to complex inter-signal heterogeneities and measurement artifacts. In particular we consider single-molecule experiments which indirectly measure the distinct steps in a b…
New methods prioritize acquiring confounding features for efficient treatment effect estimation.
problem Efficient treatment effect estimation from observational data with missing confounding information.
method Proposes two acquisition strategies: covariate balancing and reducing factual outcome error.
result Our proposed methods, especially reducing factual outcome error, improve sample efficiency for treatment effect estimation.
Valid causal inference with unobserved confounding in high-dimensional settings.
problem Estimating causal effects with unobserved confounders in high-dimensional data.
method Proposes methods to estimate causal effects with valid confidence intervals in the presence of unobserved confounders and high-dimensional nuisance models.
result Valid semiparametric inference can be obtained with unobserved confounding, and uncertainty intervals are proposed.
Spectral deconfounding improves machine learning models by reducing hidden confounding effects.
problem Machine learning models can be misled by hidden confounders, leading to unreliable predictions.
method Develops a nonlinear spectral deconfounding framework for gradient boosting that modifies boosting dynamics to slow down in confounding-aligned directions.
result Spectrally deconfounded boosting improves estimation of the target function under hidden confounding and is more scalable.
We propose a method for inferring the existence of a latent common cause ('confounder') of two observed random variables. The method assumes that the two effects of the confounder are (possibly nonlinear) functions of the confounder plus independent, additive noise. We discuss under which conditions the model is identi…
Study shows how adjusting for a binary proxy can bound causal effects.
problem Bounding causal effects with a binary confounder and proxy.
method Monotonicity assumption applied to a binary confounder and observed proxy.
result Adjusting for a proxy produces a measure of the effect between unadjusted and true measures.
Paper tackles unobserved confounding in human-AI collaborations.
problem Unobserved confounding undermines human-AI collaboration effectiveness.
method Combines sensitivity analysis from causal inference with AI-driven statistical modeling.
result Enhances robustness and reliability of collaborative outcomes.
SpaCE tackles spatial confounding in scientific studies.
problem Spatial confounding influences treatment and outcome, leading to spurious associations.
method Introduces SpaCE toolkit for benchmark datasets and tools to evaluate causal inference methods.
result Facilitates automated evaluation of machine learning and causal inference models.
Regression-Based Estimation of Causal Effects in the Presence of Selection Bias and Confoundingstat.ML
Estimates causal effects with selection bias and confounding using regression.
problem Estimating causal effects in presence of selection bias and confounding.
method Two-step regression estimator (TSR) that corrects for selection bias and accounts for confounding.
result TSR estimator reduces variance and is validated in simulations.
Paper tackles backwards-compatible data adaptation for confounded covariate and label shifts.
problem Adapt covariates to predict labels confounded with covariate shifts.
method Proposes confounded shift framework based on minimizing divergence between source and target conditional distributions, conditioning on confounders.
result Demonstrates approach on synthetic and real datasets, achieving backwards-compatible data adaptation.
Deep CITs test conditional independence in images, improving brain MRI scan analysis.
problem Testing conditional independence in complex, high-dimensional variables like images.
method Combines embedding maps and nonparametric CITs for feature representations.
result Valid DNCITs for brain MRI scans and behavioral traits, confirming null results.
Confounder Detection in High Dimensional Linear Models using First Moments of Spectral Measuresstat.ML
In this paper, we study the confounder detection problem in the linear model, where the target variable is predicted using its potential causes . Based on an assumption of rotation invariant generating process of the model, recent study shows that the spectral measure induced by the regress…
Proposes DSW for unbiased ITE estimation with dynamic confounders.
problem Estimating ITE from dynamic observational data with time-varying confounders.
method Deep Sequential Weighting (DSW) infers hidden confounders using current treatment assignments and historical information.
result DSW generates unbiased and accurate treatment effects.
Paper uses Gaussian processes to handle shared latent confounders in causal inference.
problem Bias in causal effect estimates due to shared latent confounders.
method Hierarchical Bayesian model, Gaussian processes with structured latent confounders (GP-SLC), Monte Carlo inference algorithm.
result GP-SLC provides accurate estimates of individual treatment effects with minimal assumptions.
Study linear contextual bandits with confounded offline data, improving regret bounds.
problem Linear contextual bandits with confounded offline data.
method Construct a linear bandit algorithm that utilizes projected information.
result Proved regret bounds that improve current bounds by a factor related to visible dimensionality.
With recent advances in deep learning, neuroimaging studies increasingly rely on convolutional networks (ConvNets) to predict diagnosis based on MR images. To gain a better understanding of how a disease impacts the brain, the studies visualize the salience maps of the ConvNet highlighting voxels within the brain major…
Estimates CATE under hidden confounding, accounting for bias and ignorance.
problem Learning CATE from high-dimensional data with unobserved confounders introduces bias and ignorance.
method Parametric interval estimator that accounts for hidden confounding and underrepresented samples.
result Estimator converges to tight bounds on CATE when there may be unobserved confounding.
New methods for handling confounding in observational studies.
problem Handling confounding variables in observational studies.
method Generalized coarsened procedures for clustering confounding variables, followed by estimation of treatment effects and variance.
result Developed a general asymptotic framework for the average causal effect estimator and variance formulae.
SDD improves DD for estimating treatment effects by adjusting for confounding.
problem Estimating treatment effects in observational studies with confounding.
method Synthesized Difference in Differences (SDD) using RCT data to infer correct slopes.
result SDD achieves state-of-the-art performance across synthetic and real datasets.