CNN learns diabetic syndromes from patient records.
problem Syndrome differentiation in TCM is complex and lacks standardization.
method Multi-instance multi-task learning with CNN.
result Outperforms other methods on diabetes dataset.
Syndromic surveillance detects and monitors individual and population health indicators through sources such as emergency department records. Automated classification of these records can improve outbreak detection speed and diagnosis accuracy. Current syndromic systems rely on hand-coded keyword-based methods to parse…
Data mining revealed a cluster of economic, psychological, social and cultural indicators that in combination predicted corruption and wealth of European nations. This prosperity syndrome of self-reliant citizens, efficient division of labor, a sophisticated scientific community, and respect for the law, was clearly di…
Clusters of ACS patients identified for better therapeutic stratification.
problem Data-driven classification and subtyping of ACS patients for improved treatment.
method Outcome-driven clustering using a multi-task neural network with attention.
result Seven patient clusters with distinct characteristics and risk profiles identified.
Improved logistic regression for multi-omics data improves prediction and variable selection.
problem Predicting binary class labels from multi-omics datasets with varying characteristics.
method Two-step penalized logistic regression with separate variable selection for each data layer.
result Our approach selects more relevant predictors and achieves comparable prediction performance.
Study builds machine learning models to predict ICU patients' one-year mortality.
problem Improving mortality prediction accuracy in ICU patients with heart disease.
method Developed and evaluated various machine learning models using MIMIC-III database.
result Best models achieved 85.12% prediction accuracy and AUC of 0.901.
Generative AI decodes quantum codes without labeled data.
problem Efficient decoding of quantum error-correcting codes.
method Generative Transformers learn logical operators from unsupervised syndromes.
result Significantly better decoding accuracy than traditional methods.
Machine learning improves detection of Brugada Syndrome from ECGs.
problem Detecting Brugada Syndrome (BrS) from ECGs is challenging due to limited diagnostic criteria.
method Pipeline that reads and processes scanned ECG images, uses LSTM classifier to diagnose.
result The proposed pipeline distinguishes between ECG types and diagnoses BrS with high accuracy.
Study uses LCA to identify ARDS sub-phenotypes improving predictive models.
problem Complex and heterogeneous nature of ARDS makes early recognition difficult.
method Applied latent class analysis to identify sub-groups, then built predictive models.
result Significantly improved prediction performance for two sub-phenotypes of ARDS.
The paper prices a new life insurance policy for couples, considering various contingent benefits.
problem Valuation of life insurance policies for dependent coupled lives.
method Employed the QP-rule combining real-world and risk-neutral measures for pricing. result Explicit pricing expressions for the new insurance policy were derived and analyzed.
High-performance quantum codes decoded with minimal data.
problem Efficient decoding of linear-rate LDPC quantum codes.
method Tessellations of hyperbolic manifolds, Coxeter groups, and Galois fields.
result Achieved encoding rate of 13/72 with high performance.
Enhanced mortality prediction model using EHR and free-text data.
problem Predicting one-year mortality in AMI patients.
method Used deep learning models with word embedding features from free-text discharge summaries.
result Significant improvement in model performance (92.89% accuracy, 0.928 F-measure).
This paper automates mining of COVID-19 scholarly articles using machine learning.
problem Time-consuming and impractical manual extraction of relevant COVID-19 research articles.
method Used machine learning approaches, specifically clustering and parallel one-class support vector machines (OCSVMs), on the CORD-19 dataset.
result Parallel OCSVMs outperform other methods for both original and reduced feature space.
ECG signal learning predicts cardiovascular death risk.
problem Scarce positive ECG event examples and class imbalance.
method Multiple instance learning framework for raw ECG signals.
result Learned risk score outperforms existing metrics.
DSM improves visual quality of fetoscopic videos by mosaicking.
problem Challenges in identifying all vascular connections during fetoscopy due to low visual quality and drift.
method Proposes a Deep Sequential Mosaicking (DSM) framework using deep learning techniques to handle visual variations and reduce drift.
result DSM framework reduces accumulated drift and improves visual quality of fetoscopic videos.
Bayesian deep learning predicts satellite collisions.
problem Space debris poses planetary risk.
method Bayesian deep learning with LSTM networks.
result Predicts conjunction event evolution with uncertainties.
A Convolutional Neural Network was used to predict kidney function in patients with chronic kidney disease from high-resolution digital pathology scans of their kidney biopsies. Kidney biopsies were taken from participants of the NEPTUNE study, a longitudinal cohort study whose goal is to set up infrastructure for obse…
Develops a risk score to assist ECMO planning for critically ill patients with viral or unspecified pneumonia.
problem Lack of a risk score to guide ECMO planning for critically ill patients.
method Leverages machine learning to develop the PEER score.
result PEER score predicts mortality and decompensation in patients eligible for ECMO.
Study uses machine learning to identify posturographic features in Parkinson's patients who fall.
problem Identifying patients at risk of falling in Parkinson's syndrome.
method Employed ts-AUC, a non-parametric multivariate two-sample test, to analyze posturographic features.
result Significant differences in antero-posterior movements and posturographic area between fallers and non-fallers identified.
Harmonization schemes limit accuracy due to domain information.
problem Harmonization schemes lead to inaccurate predictions due to domain information.
method Analysis of mutual information and real label value informativeness.
result Accuracy is limited by the domain with least information.
Olympic Games consistently exceed budgets, leading to unpredictable costs.
problem High costs and unpredictability of the Olympic Games.
method Statistical analysis of historical data to explain cost risks.
result Olympic costs follow a power-law distribution with infinite mean and variance.
Deep learning system tracks stool consistency for GI disease assessment.
problem Lack of objective stool consistency measurements in chronic GI disease.
method Computer vision and deep convolutional neural networks (CNN).
result Developed a stool detection and tracking system.
Accounting frameworks follow stipulations of existing Accounting Theories. This exploratory research sets out to trace the evolution of accounting theories of Charge and Discharge Syndrome and the Corollary of Double Entry. Furthermore, it dives into the theories of Income Determination, garnishing it with areas of div…
Machine learning aids in diagnosing Parkinson's disease with higher accuracy.
problem Subjectivity in traditional PD diagnosis methods and missed early symptoms.
method Machine learning applied to various data modalities for PD and control group classification.
result Machine learning methods show high potential for improving PD diagnosis.
Mobile electrocardiogram (ECG) recording technologies represent a promising tool to fight the ongoing epidemic of cardiovascular diseases, which are responsible for more deaths globally than any other cause. While the ability to monitor one's heart activity at any time in any place is a crucial advantage of such techno…
The paper proposes a method to predict the performance of data-driven algorithms using surrogate models.
problem Improving the performance prediction of data-driven knowledge discovery algorithms.
method Surrogate-assisted performance prediction using evolutionary modeling of clinical pathways.
result The proposed approach provides interpretable prediction of algorithm performance and quality.
Study improves LLMs for PPI analysis by addressing uncertainty.
problem Uncertainty in LLM predictions for PPIs.
method Fine-tuned LLaMA-3 and BioMedGPT models, LoRA ensembles, Bayesian LoRA for UQ.
result Competitive PPI identification performance across diverse disease contexts.
Cryptofinance generates yield through innovative decentralized finance.
problem Lack of intrinsic yield in crypto-assets.
method Analysis of yield-generating mechanisms in cryptofinance.
result Cryptofinance innovations enable yield generation through various decentralized and centralised mechanisms.
Deep neural network identifies potential SARS-CoV-2 inhibitors.
problem Finding novel therapies for SARS-CoV-2.
method Used ChemAI, a deep neural network trained on 220M data points, to screen and rank one billion molecules from the ZINC database.
result Identified 30,000 top-ranked compounds for further bioassays.
Medical researchers are coming to appreciate that many diseases are in fact complex, heterogeneous syndromes composed of subpopulations that express different variants of a related complication. Time series data extracted from individual electronic health records (EHR) offer an exciting new way to study subtle differen…
Study repurposes open data to find potential COVID-19 drugs.
problem Developing effective treatments for COVID-19.
method Deep learning network-based approach using large scientific corpus.
result Identified 41 repurposable drugs for COVID-19.
Develops a novel approach for estimating optimal DTRs with multicategory treatments and censored data.
problem Estimating optimal treatment regimes for chronic diseases with censored data.
method Angle-based multicategory classification algorithm for maximizing conditional survival function.
result The proposed method outperforms existing approaches in maximizing conditional survival function.
AI and HPC help screen millions of molecules for SARS-CoV-2 treatments.
problem Finding effective treatments for SARS-CoV-2.
method AI and HPC enable screening of large molecule datasets.
result Data release of 23 datasets with 4.2 billion molecules.
Early and accurate identification of parkinsonian syndromes (PS) involving presynaptic degeneration from non-degenerative variants such as Scans Without Evidence of Dopaminergic Deficit (SWEDD) and tremor disorders, is important for effective patient management as the course, therapy and prognosis differ substantially …
Deep learning ensembles improve COVID-19 detection from chest X-rays.
problem Detecting COVID-19 from chest X-rays using machine learning.
method Custom CNN and ImageNet models, transfer learning, iterative pruning, ensemble learning.
result 99.01% accuracy in detecting COVID-19 from chest X-rays.
DeTraC CNN detects COVID-19 from chest X-rays with high accuracy.
problem Limited availability of annotated medical images for COVID-19 diagnosis.
method Transfer learning and class decomposition mechanism in DeTraC CNN.
result 95.12% accuracy in detecting COVID-19 from normal and severe cases.
Many complex disease syndromes such as asthma consist of a large number of highly related, rather than independent, clinical phenotypes, raising a new technical challenge in identifying genetic variations associated simultaneously with correlated traits. In this study, we propose a new statistical framework called grap…
ECGDetect uses deep learning to detect ischemia in heart ECGs.
problem Detecting early signs of acute coronary syndrome in patients.
method Developed a deep learning model using the LTST database.
result Deep neural network achieved 90.31% ROC-AUC, 89.34% sensitivity, 87.81% specificity.
A typical problem in causal modeling is the instability of model structure learning, i.e., small changes in finite data can result in completely different optimal models. The present work introduces a novel causal modeling algorithm for longitudinal data, that is robust for finite samples based on recent advances in st…
Causal modeling has long been an attractive topic for many researchers and in recent decades there has seen a surge in theoretical development and discovery algorithms. Generally discovery algorithms can be divided into two approaches: constraint-based and score-based. The constraint-based approach is able to detect co…
New protocols implement logical gates on encoded qubits with minimal overhead.
problem Efficiently performing universal logical gates on encoded qubits with minimal overhead.
method Using topological codes associated to hyperbolic surfaces, we introduce protocols to implement Dehn twists through constant depth unitary circuits.
result Demonstrated the possibility of applying universal logical gate sets on encoded qubits through constant depth unitary circuits and with constant space overhead.
Study tackles variable selection with missing covariates and outcomes using machine learning and imputation.
problem Missing data in both covariates and outcomes complicates variable selection in health studies.
method Exploits machine learning flexibility and bootstrap imputation for variable selection, comparing multiple methods.
result XGBoost and BART perform best in variable selection with bootstrap imputation, achieving high F1 scores and low Type I errors. Predictive models identify patients at risk of severe COVID-19.
problem Identifying patients at risk of severe COVID-19 to ease healthcare strain.
method Machine learning on routinely collected clinical data.
result Models predict positive SARS-CoV-2 tests, hospitalizations, and critical care with high accuracy.
Study develops an interpretable model for early mortality prediction in elderly MODS patients.
problem High mortality risk in elderly patients with MODS, unsatisfactory current scoring systems.
method Used eXtreme Gradient Boosting with SHapley Additive exPlanations on MIMIC-III, eICU-CRD, and PLAGH-S datasets.
result Interpretable model outperforms baseline models and clinical scores in predicting hospital mortality.
Study identifies three sub-phenotypes of AKI with different severity.
problem Tackles the heterogeneity of AKI to improve targeted interventions.
method Used a memory network-based deep learning approach on EHR data.
result Identified three distinct sub-phenotypes of AKI with varying severity.
A new bandit problem where experiments can be interrupted if results are not promising.
problem Interruptible multi-armed bandit problem with a threshold for cumulative reward.
method Formalized survival regret, identified key components (regret and probability of ruin), derived lower bounds and optimal policies.
result No policy can achieve sublinear survival regret, but optimal policies minimize survival regret in a Pareto sense.
The closure conditions of the inexact exterior differential form and dual form (an equality to zero of differentials of these forms) can be treated as a definition of some differential-geometrical structure. Such a connection discloses the properties and specific features of the differential-geometrical structures. The…
Differential completions and compactifications of differential spaces are introduced and investigated. The existence of the maximal differential completion and the maximal differential compactification is proved. A sufficient condition for the existence of a complete uniform differential structure on a given differenti…