New model identifies cell-specific genes for cancer prognosis.
problem No statistical model to integrate multiscale cancer data.
method Bayesian generalized promotion time cure models (GPTCMs).
result Improves cancer prognosis by identifying cell-specific genes.
SurvCORN predicts survival curves using conditional ordinal ranking networks.
problem Challenges in survival analysis with censored data.
method SurvCORN: Conditional Ordinal Ranking Neural Network.
result SurvCORN improves accuracy in predicting time-to-event outcomes.
Quantitative CT predicts ILD patterns and prognosis.
problem Diagnosing and predicting prognosis of fibrosing ILD patterns.
method High-resolution CT texture features, TM model for classification and survival analysis.
result TM model outperforms histogram-based model in distinguishing UIP from non-UIP patterns and allows for survival group partitioning.
Automated brain tumor segmentation plays an important role in the diagnosis and prognosis of the patient. In addition, features from the tumorous brain help in predicting patients overall survival. The main focus of this paper is to segment tumor from BRATS 2018 benchmark dataset and use age, shape and volumetric featu…
Survival analysis in the presence of multiple possible adverse events, i.e., competing risks, is a pervasive problem in many industries (healthcare, finance, etc.). Since only one event is typically observed, the incidence of an event of interest is often obscured by other related competing events. This nonidentifiabil…
HACSurv models dependencies between competing risks and censoring for improved survival analysis.
problem Inaccurate survival predictions due to ignoring dependencies between competing risks and censoring.
method HACSurv uses hierarchical Archimedean copulas to model dependencies and cause-specific survival functions.
result HACSurv improves accuracy in survival predictions and captures complex risk interactions.
SurvFM-RMST converts survival outcomes into pseudo-observation targets for tabular models.
problem Right-censored follow-up prevents direct use of survival labels in tabular patient data.
method SurvFM-RMST framework that converts survival outcomes into jackknife pseudo-observation targets for restricted mean survival time.
result SurvFM-RMST accurately recovered restricted event-free time in simulations and outperformed naive targets in static datasets.
Breast cancer is the most frequently reported cancer type among the women around the globe and beyond that it has the second highest female fatality rate among all cancer types. Despite all the progresses made in prevention and early intervention, early prognosis and survival prediction rates are still unsatisfactory. …
Bayesian Cox model identifies biomarkers from multi-omics data.
problem Produce interpretable survival prognosis from multi-omics data.
method Penalized semiparametric Bayesian Cox model with graph-structured selection priors.
result Model identifies new biomarkers and improves survival prediction.
Survival month for non-small lung cancer patients depend upon which stage of lung cancer is present. Our aim is to identify smoking specific gene expression biomarkers in the prognosis of lung cancer patients. In this paper, we introduce the network elastic net, a generalization of network lasso that allows for simulta…
Deep learning has shown remarkable results for image analysis and is expected to aid individual treatment decisions in health care. To achieve this, deep learning methods need to be promoted from the level of mere associations to being able to answer causal questions. We present a scenario with real-world medical image…
Accurate prediction of disease trajectories is critical for early identification and timely treatment of patients at risk. Conventional methods in survival analysis are often constrained by strong parametric assumptions and limited in their ability to learn from high-dimensional data, while existing neural network mode…
Study compares Cox model and RSF for predicting patient survival, finding RSF superior in certain scenarios.
problem Comparing predictive accuracy of Cox proportional hazards model and Random Survival Forest for patient-specific survival probabilities.
method Conducted a comprehensive comparison study using simulation scenarios and real-world datasets.
result RSF outperforms Cox model in nonproportional hazards settings and with treatment-covariate interactions.
CN-SBM clusters cancer samples and regions based on copy number variants.
problem Clonal evolution in cancer monitored by noisy copy number variants.
method Probabilistic framework using bipartite categorical block model.
result Improved model fit and clinically relevant subtypes identified.
Background: Choosing the most performing method in terms of outcome prediction or variables selection is a recurring problem in prognosis studies, leading to many publications on methods comparison. But some aspects have received little attention. First, most comparison studies treat prediction performance and variable…
Unlike common cancers, such as those of the prostate and breast, tumor grading in rare cancers is difficult and largely undefined because of small sample sizes, the sheer volume of time needed to undertake on such a task, and the inherent difficulty of extracting human-observed patterns. One of the most challenging exa…
We explore how Deep Learning (DL) can be utilized to predict prognosis of acute myeloid leukemia (AML). Out of TCGA (The Cancer Genome Atlas) database, 94 AML cases are used in this study. Input data include age, 10 common cytogenetic and 23 most common mutation results; output is the prognosis (diagnosis to death, DTD…
fiBAG integrates multiplatform genomic data to identify disease markers.
problem Understanding complex mechanisms underlying human diseases from multiplatform genomic data.
method fiBAG uses Gaussian process models and Bayes factors to identify functional evidence and guide variable selection.
result fiBAG improves detection of disease-related markers compared to non-integrative methods.
Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histologic sub-regions, i.e., peritumoral edematous/invaded tissue, necrotic core, active and non-enhancing core. This intrinsic heterogeneity is also portrayed in their radio-p…
CovidCare uses EMR data to predict patient outcomes in emerging epidemics.
problem Intelligent prognosis for patients with emerging infectious diseases during rapid epidemics.
method Transfer learning and knowledge distillation from existing EMR data.
result CovidCare outperforms baseline methods in predicting patient length of stay.
SurvMixClust clusters survival data and predicts individual survival curves.
problem Integrating clustering into survival analysis for precision medicine.
method SurvMixClust learns latent representations for clustering and predicts survival functions using a mixture of non-parametric experts.
result SurvMixClust creates balanced clusters with distinct survival curves, outperforming clustering baselines and competing with non-clustering models in predictive accuracy.
The paper predicts survival functions using random survival trees and concordance maximization.
problem Predicting conditional survival functions in right-censored data.
method The approach combines regression strategies with random survival trees and maximizes concordance.
result The proposed weighted predictor outperforms the usual survival cobra in terms of concordance.
Survival kernets scale deep kernel survival analysis to large datasets with interpretability and theoretical guarantees.
problem Scalable and interpretable deep kernel survival analysis for large datasets.
method Survival kernets use kernel netting for training set compression and XGBoost for warm-starting neural architecture search.
result Survival kernets achieve optimal time-dependent concordance index on various survival analysis datasets.
Survival MDN uses invertible functions to speed up survival analysis models.
problem Training neural ODEs for survival analysis is computationally expensive.
method Survival MDN applies an invertible positive function to MDN outputs.
result Survival MDN outperforms or matches other models on concordance, Brier score, and log-likelihood.
RSM provides insights into deep survival models' decision-making.
problem Ensuring trust in deep survival models' predictions for healthcare applications.
method Reverse survival model (RSM) framework that explains deep survival models' decisions.
result RSM extracts relevant features for deep survival models' predictions.
Neural network learns kernel functions for survival analysis and prediction intervals.
problem Predicting survival times for individuals based on similar training subjects.
method Develops a neural network framework to learn kernel functions for kernel survival analysis and uses these to construct valid prediction intervals.
result Neural network survival estimators are competitive with existing methods and provide valid prediction intervals.
Reduces survival analysis to common regression tasks.
problem Applying standard machine learning tools to survival analysis.
method Various reduction techniques to simplify survival analysis.
result Benchmark analysis shows improved predictive performance.
A new method clusters survival data using deep variational models.
problem Clustering survival data, a challenging task.
method Semi-supervised probabilistic approach with deep generative model.
result The method outperforms previous models in clustering and predicting survival times.
We investigate the effect of the proportional hazards assumption on prognostic and predictive models of the survival time of patients suffering from amyotrophic lateral sclerosis (ALS). We theoretically compare the underlying model formulations of several variants of survival forests and implementations thereof, includ…
Optimal Survival Trees improve accuracy in medical data analysis.
problem Analyzing censored outcomes in medical data.
method Mixed-integer optimization and local search techniques.
result Improves accuracy in large datasets compared to existing methods.
RSF models censored functional data for better survival analysis.
problem Modeling survival trajectories with censored data.
method Random Survival Forest for Censored Functional Data (RSF).
result Good performance in predicting survival variables.
Improves survival analysis across multiple domains with machine learning.
problem Adapting survival analysis to new or rare illness types with limited labeled data.
method Introduces a new survival metric and discrepancy measure for censored data, enabling domain adaptation.
result Superb performance on target domains, better treatment recommendations, and interpretable weight matrix.
Optimal survival trees ensemble reduces tree count and improves predictive performance.
problem Improving predictive performance in survival analysis.
method Grows a forest of optimal survival trees by ranking and selecting the best trees based on out-of-bag error.
result Reduces the number of trees in the ensemble while improving predictive performance.
In this paper we utilize a survival analysis methodology incorporating Bayesian additive regression trees to account for nonlinear and additive covariate effects. We compare the performance of Bayesian additive regression trees, Cox proportional hazards and random survival forests models for censored survival data, usi…
Efficiently clusters survival curves without computationally intensive resampling.
problem Identifying clusters of survival curves efficiently and scalably.
method Log-rank test combined with k-means clustering.
result Achieves comparable results to bootstrap-based methods but with improved efficiency.
Interpretable survival analysis improves heart failure risk prediction.
problem Improving heart failure risk prediction using survival analysis.
method Survival stacking, ControlBurn, Explainable Boosting Machines.
result Achieves state-of-the-art performance and provides novel insights.
A data-driven approach predicts morphological development under structural instability.
problem Understanding and predicting spatiotemporal complexities of morphogenesis under structural instability.
method Machine-learning framework based on physical modeling of morphogenesis.
result Identification of key bifurcation characteristics and prediction of history-dependent development.
auton-survival simplifies survival analysis for healthcare data.
problem Handling censored time-to-event data in healthcare.
method Open-source package for survival regression, adjustment, counterfactual estimation, phenotyping, and treatment effects.
result Demonstrates auton-survival's ability to support complex health and epidemiological questions.
SurvBESA predicts survival times using ensemble methods with self-attention.
problem Challenges in survival analysis due to censored data and unstable predictions.
method SurvBESA combines Beran estimators with a self-attention mechanism to predict survival times.
result SurvBESA outperforms state-of-the-art models in predicting survival times.
GBEST model improves survival analysis for small datasets.
problem Challenges in survival analysis, especially with small data.
method Bayesian bootstrap and Beta Stacy bootstrap methods integrated into bagging tree models.
result GBEST model outperforms classical survival models in predictive performance and stability.
SurvFD and SurvSHAP-IQ provide interpretable survival models by analyzing feature interactions.
problem Non-additivity of hazard and survival functions limits standard additive explanation methods.
method SurvFD decomposes higher-order effects into time-dependent and time-independent components, extending Shapley interactions to time-indexed functions.
result SurvFD and SurvSHAP-IQ offer a new perspective on survival explanations, explicitly characterizing feature interactions.
Enhances patient failure prediction using dynamic survival models.
problem Lack of precise individual level prediction in conventional models.
method Developed counterfactual dynamic survival model (CDSM).
result Inflection point of estimated survival curves predicts patient failure time.
FinSurvival provides a large-scale financial survival modeling benchmark.
problem Lack of large-scale, realistic, and freely available datasets for benchmarking AI survival models.
method Derived 16 survival modeling tasks from cryptocurrency lending data using an automated pipeline.
result Demonstrated that existing AI survival models are not well-suited for these challenging tasks.
Paper proposes a new combined regression strategy for conditional survival prediction.
problem Improving survival prediction accuracy using conditional survival function.
method Uses regression-based weak learners with area-norm proximity measure to create an ensemble technique.
result The proposed model outperforms Random Survival Forest and selects important variables effectively.
Paper proposes robust methods for estimating optimal treatment rules with censored survival data.
problem Estimating optimal treatment rules for censored survival data.
method Developed two robust criteria and a sampling-based difference-of-convex algorithm for learning optimal treatment rules.
result Proposed methods show improved performance compared to existing methods in simulations and real data.
Bayesian framework improves survival prediction accuracy and uncertainty quantification.
problem Inaccurate uncertainty estimates in survival models.
method Bayesian framework combining variational inference, neural multi-task logistic regression, and sparsity-inducing prior.
result Better quantification of survival uncertainty and more accurate predictions.
CDVI improves variational inference for survival analysis by considering censoring mechanisms.
problem Challenges in applying variational methods to survival data, especially the dependence on censoring.
method Censor-dependent variational inference (CDVI) tailored for latent variable models in survival analysis.
result Significant improvements in estimating individual survival distributions.
Enhances interpretability of functional survival models.
problem Lack of interpretability in functional survival models limits practical use.
method Introduces novel methods to enhance interpretability of FST and explainability of FRSF.
result Proposed methods yield efficient, easy-to-understand decision trees.