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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,742 papers · 148 categories

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11233445 · May 202619922001200920172026
48 results for surrogate markers

Improves disease progression prediction using auxiliary surrogate labels and health markers.

problem Challenges in predicting disease progression due to unknown true disease states.
method Integrates hidden Markov model with time-varying discriminative classification model.
result Significant improvement in distinguishing LBD from AD using objective markers.

The paper proposes a method to assess surrogate heterogeneity in non-randomized data.

problem Lack of methods to evaluate surrogate heterogeneity in non-randomized data.
method Proposes a framework using meta-learners to assess surrogate heterogeneity in real-world data.
result Identifies individuals for whom the surrogate is a valid replacement of the primary outcome.

SCIENCE improves prediction intervals for individual causal effects.

problem Wide prediction intervals limit practical utility of causal inference.
method Surrogate-assisted conformal inference for efficient individual causal effects.
result SCIENCE produces more efficient prediction intervals for individual causal effects.

Novel method identifies proteomic risk markers for Alzheimer disease.

problem Lack of comprehensive proteomic risk markers for Alzheimer disease diagnosis.
method Deep belief network-based feature selection method using proteomic and clinical data.
result Identified an optimal subset of proteins achieving 90% accuracy in Alzheimer disease diagnosis.

AR app visualizes Quranic Surah al-Fil for Islamic education.

problem Lack of interactive and context-rich learning materials for Quranic studies.
method Research and development approach, including data collection, user requirement analysis, interface design, 3D asset creation, and integration of AR technology.
result AR application achieved high accuracy and user satisfaction, enhancing learner engagement and understanding.

MarkerMap selects key genes for cell type analysis in single-cell RNA-seq.

problem Selecting informative genes from large single-cell RNA-seq datasets is challenging and computationally intensive.
method MarkerMap is a generative model that identifies minimal gene sets explaining cell type variability.
result MarkerMap outperforms existing methods in both supervised and unsupervised marker selection.

Predicts clinical events using a landmark approach with machine learning for large biomarker histories.

problem Dynamic prediction of clinical events from large biomarker histories.
method Landmark approach extended to endogenous markers history combined with machine learning methods for survival data.
result Superlearner combining regularized regressions and random survival forests outperforms standard survival models.

This paper introduces the factorial marked temporal point process model and presents efficient learning methods. In conventional (multi-dimensional) marked temporal point process models, event is often encoded by a single discrete variable i.e. a marker. In this paper, we describe the factorial marked point processes w…

2018-01-21abs ↗pdf ↗

CNMs detect tipping points in complex systems using causal network markers.

problem Identifying tipping points ahead of critical transitions in complex systems.
method Introducing CNMs that incorporate causality indicators to detect tipping points.
result CNMs show higher predictive power and accuracy than traditional DNB indicators.

Preterm birth is the most common cause of neonatal death. Current diagnostic methods that assess the risk of preterm birth involve the collection of maternal characteristics and transvaginal ultrasound imaging conducted in the first and second trimester of pregnancy. Analysis of the ultrasound data is based on visual i…

2019-08-24abs ↗pdf ↗

fiBAG integrates multiplatform genomic data to identify disease markers.

problem Understanding complex mechanisms underlying human diseases from multiplatform genomic data.
method fiBAG uses Gaussian process models and Bayes factors to identify functional evidence and guide variable selection.
result fiBAG improves detection of disease-related markers compared to non-integrative methods.

Quantifying behavior is crucial for many applications in neuroscience. Videography provides easy methods for the observation and recording of animal behavior in diverse settings, yet extracting particular aspects of a behavior for further analysis can be highly time consuming. In motor control studies, humans or other …

2018-04-09abs ↗pdf ↗

We describe a method that infers whether statistical dependences between two observed variables X and Y are due to a "direct" causal link or only due to a connecting causal path that contains an unobserved variable of low complexity, e.g., a binary variable. This problem is motivated by statistical genetics. Given a ge…

2012-02-14abs ↗pdf ↗

Study uses DNM theory to detect early warning signals of market instability.

problem Detecting early warning signals of financial market instability.
method Applying Dynamical Network Marker (DNM) theory to trading data from the Tokyo Stock Exchange.
result Early warning signals of large price movements can be detected on a daily time scale.

The paper proposes a method to integrate prior information into penalized regression.

problem Improving predictive performance in high-dimensional tasks with prior information.
method Integrating multiple sources of prior information into penalized regression.
result The method improves predictive performance, as shown by simulations and applications.

Proposes a two-stage method for estimating heterogeneous treatment effects using gradient boosting trees.

problem Estimating heterogeneous treatment effects in randomized clinical trials with high-dimensional predictive markers.
method Two-stage statistical learning procedure using gradient boosting trees (XGBoost) to estimate main effects and HTE.
result Improves efficiency in estimating heterogeneous treatment effects through nonparametric function estimation.

The paper analyzes the observability of relative pose estimation using dual quaternions.

problem Estimating relative pose in robotics applications.
method Lie algebraic nonlinear observability analysis on a dual quaternion system.
result Dual quaternion representation yields an observability matrix with a simple block triangular structure and full rank.

New method classifies reticulocytes from red blood cells without labels.

problem Classifying reticulocytes from mature red blood cells without fluorescent labels.
method Unsupervised machine learning on morpho-rheological markers.
result Promising results in classifying reticulocytes from mature red blood cells.

Let R be an o-minimal expansion of the real field. We introduce a class of Hausdorff limits, the T-infinity limits over R, that do not in general fall under the scope of Marker and Steinhorn's definability-of-types theorem. We prove that if R admits analytic cell decomposition, then every T-infinity limit over R is def…

2011-07-04abs ↗pdf ↗

In many data exploration tasks it is meaningful to identify groups of attribute interactions that are specific to a variable of interest. For instance, in a dataset where the attributes are medical markers and the variable of interest (class variable) is binary indicating presence/absence of disease, we would like to k…

2016-12-22abs ↗pdf ↗

We formalize and study the natural approach of designing convex surrogate loss functions via embeddings, for problems such as classification, ranking, or structured prediction. In this approach, one embeds each of the finitely many predictions (e.g.\ rankings) as a point in Rd\mathbb{R}^d, assigns the original loss val…

2019-07-17abs ↗pdf ↗

The paper proposes a scalable framework for uncertainty quantification and propagation in surrogate-based Bayesian inference.

problem Uncertainty in surrogate models and its impact on inference and decision-making.
method Bayesian inference methods for surrogate models with measurement data.
result Scalable framework for uncertainty quantification and propagation in surrogate models.

Paper proposes hybrid modeling to improve surrogate accuracy using multiple data sources.

problem Improving surrogate model accuracy by integrating simulation and real-world data.
method Two novel probabilistic approaches: separate and combined surrogates with weighting strategy.
result Hybrid models improve predictive accuracy and coverage compared to single-source surrogates.

This paper develops efficient surrogate models for optimization of complex dynamical systems.

problem Computational expense in solving complex dynamical systems through numerical simulation.
method Combination of proper orthogonal decomposition and radial basis functions for constructing low-dimensional surrogate models.
result Surrogate models reduce computational time for optimization problems while maintaining accuracy.

This work improves surrogate models for balancing accuracy and cost in multi-fidelity methods.

problem Balancing accuracy and computational cost in multi-fidelity methods.
method Develops context-aware surrogate models for multi-fidelity importance sampling and Bayesian inverse problems.
result Context-aware surrogate models can lead to runtime speedups of up to one order of magnitude.

Adversarial consistency depends on the uniqueness of adversarial Bayes classifiers.

problem Consistency of adversarial surrogate losses is not guaranteed.
method Connected consistency of adversarial surrogate losses to the uniqueness of adversarial Bayes classifiers.
result A convex surrogate loss is statistically consistent for adversarial learning if and only if the adversarial Bayes classifier is unique.

New method simplifies checking consistency of differentiable loss functions.

problem Verifying consistency of differentiable loss functions is difficult.
method Developed a new approach called strong indirect elicitation (strong IE) to simplify checking consistency.
result Strong IE is equivalent to calibration for strongly convex, differentiable surrogates.