PHASE predicts surgical complications from physiological signals.
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Deep learning models predict postoperative complications more accurately than random forests.
We aim to create a framework for transfer learning using latent factor models to learn the dependence structure between a larger source dataset and a target dataset. The methodology is motivated by our goal of building a risk-assessment model for surgery patients, using both institutional and national surgical outcomes…
A large fraction of the electronic health records consists of clinical measurements collected over time, such as blood tests, which provide important information about the health status of a patient. These sequences of clinical measurements are naturally represented as time series, characterized by multiple variables a…
Stratifying patients at risk for postoperative complications may facilitate timely and accurate workups and reduce the burden of adverse events on patients and the health system. Currently, a widely-used surgical risk calculator created by the American College of Surgeons, NSQIP, uses 21 preoperative covariates to asse…
Automated surgical workflow analysis and understanding can assist surgeons to standardize procedures and enhance post-surgical assessment and indexing, as well as, interventional monitoring. Computer-assisted interventional (CAI) systems based on video can perform workflow estimation through surgical instruments' recog…
Surgeons normally need surgical scissors and tissue grippers to cut through a deformable surgical tissue. The cutting accuracy depends on the skills to manipulate these two tools. Such skills are part of basic surgical skills training as in the Fundamentals of Laparoscopic Surgery. The gripper is used to pinch a point …
Objective: A median of 14.4% of patient undergone at least one adverse event during surgery and a third of them are preventable. The occurrence of adverse events forces surgeons to implement corrective strategies and, thus, deviate from the standard surgical process. Therefore, it is clear that the automatic identifica…
Paper proposes an active learning method for surgical workflow recognition using long-range temporal dependency.
We use a deep learning model trained only on a patient's blood oxygenation data (measurable with an inexpensive fingertip sensor) to predict impending hypoxemia (low blood oxygen) more accurately than trained anesthesiologists with access to all the data recorded in a modern operating room. We also provide a simple way…
Over the past one hundred years, the classic teaching methodology of "see one, do one, teach one" has governed the surgical education systems worldwide. With the advent of Operation Room 2.0, recording video, kinematic and many other types of data during the surgery became an easy task, thus allowing artificial intelli…
Purpose: Manual feedback from senior surgeons observing less experienced trainees is a laborious task that is very expensive, time-consuming and prone to subjectivity. With the number of surgical procedures increasing annually, there is an unprecedented need to provide an accurate, objective and automatic evaluation of…
We develop a novel algorithm to predict the occurrence of major abdominal surgery within 5 years following Crohn's disease diagnosis using a panel of 29 baseline covariates from the Swedish population registers. We model pseudo-observations based on the Aalen-Johansen estimator of the cause-specific cumulative incidenc…
The paper uses facial keypoints to estimate post-surgical pain intensity.
Vision algorithms capable of interpreting scenes from a real-time video stream are necessary for computer-assisted surgery systems to achieve context-aware behavior. In laparoscopic procedures one particular algorithm needed for such systems is the identification of surgical phases, for which the current state of the a…
Evaluating surgeon skill has predominantly been a subjective task. Development of objective methods for surgical skill assessment are of increased interest. Recently, with technological advances such as robotic-assisted minimally invasive surgery (RMIS), new opportunities for objective and automated assessment framewor…
Paper introduces OTR for efficient offline RL in surgical robotics.
We give a criterion under which a solution g(t) of the Kahler-Ricci flow contracts exceptional divisors on a compact manifold and can be uniquely continued on a new manifold. As t tends to the singular time T from each direction, we prove convergence of g(t) in the sense of Gromov-Hausdorff and smooth convergence away …
Despite spectacular advances in defining invariants for simply connected smooth and symplectic 4-dimensional manifolds and the discovery of effective surgical techniques, we still have been unable to classify simply connected smooth manifolds up to diffeomorphism. In these notes, adapted from six lectures given at the …
The study uses transfer learning to compare surgical outcomes across racial/ethnic subgroups.
Reducing the incidence of surgical site infections (SSIs) is one of the objectives of the French nosocomial infection control program. Manual monitoring of SSIs is carried out each year by the hospital hygiene team and surgeons at the University Hospital of Bordeaux. Our goal was to develop an automatic detection algor…
We augment linear Support Vector Machine (SVM) classifiers by adding three important features: (i) we introduce a regularization constraint to induce a sparse classifier; (ii) we devise a method that partitions the positive class into clusters and selects a sparse SVM classifier for each cluster; and (iii) we develop a…
It is well-known that any pair of closed orientable 3-manifolds are related by a finite sequence of Dehn surgeries on knots. Furthermore Kawauchi showed that such knots can be taken to be hyperbolic. In this article, we consider the minimal length of such sequences connecting a pair of 3-manifolds, in particular, a pai…
Bayesian models can be tricked into believing false data.
Develops a risk score to assist ECMO planning for critically ill patients with viral or unspecified pneumonia.
We prove that a general complex Monge-Ampère flow on a Hermitian manifold can be run from an arbitrary initial condition with zero Lelong number at all points. Using this property, we confirm a conjecture of Tosatti-Weinkove: the Chern-Ricci flow performs a canonical surgical contraction. Finally, we study a generaliza…
The premorbid geometry of the mandible is of significant relevance in jaw reconstructive surgeries and occasionally unknown to the surgical team. In this paper, an optimization framework is introduced to train deep models for completion (reconstruction) of the missing segments of the bone based on the remaining healthy…
The morphometry of a kidney tumor revealed by contrast-enhanced Computed Tomography (CT) imaging is an important factor in clinical decision making surrounding the lesion's diagnosis and treatment. Quantitative study of the relationship between kidney tumor morphology and clinical outcomes is difficult due to data scar…
We prove a monotonicity formula for mean curvature flow with surgery. This formula differs from Huisken's monotonicity formula by an extra term involving the mean curvature. As a consequence, we show that a surgically modified flow which is sufficiently close to a smooth flow in the sense of geometric measure theory is…
Hospital readmissions have become one of the key measures of healthcare quality. Preventable readmissions have been identified as one of the primary targets for reducing costs and improving healthcare delivery. However, most data driven studies for understanding readmissions have produced black box classification and p…
3D U-Net improves kidney and tumor segmentation from CT scans.
Hybrid method improves accuracy and speed of breast model parameter estimation.
Study describes severe dengue ICU patients in Brazil, 2012-2024.
Type 2 diabetes mellitus (T2DM) is a chronic disease that often results in multiple complications. Risk prediction and profiling of T2DM complications is critical for healthcare professionals to design personalized treatment plans for patients in diabetes care for improved outcomes. In this paper, we study the risk of …
We show that quasi-alternating links arise naturally when considering surgery on a strongly invertible L-space knot (that is, a knot that yields an L-space for some Dehn surgery). In particular, we show that for many known classes of L-space knots, every sufficiently large surgery may be realized as the two-fold branch…
In many safety-critical applications such as autonomous driving and surgical robots, it is desirable to obtain prediction uncertainties from object detection modules to help support safe decision-making. Specifically, such modules need to estimate the probability of each predicted object in a given region and the confi…
A benchmark evaluates ioUS-to-MR synthesis methods for brain tumor surgery.
Joint replacement is the most common inpatient surgical treatment in the US. We investigate the clinical pathway optimization for knee replacement, which is a sequential decision process from onset to recovery. Based on episodic claims from previous cases, we view the pathway optimization as an intelligence crowdsourci…
Clinical measurements collected over time are naturally represented as multivariate time series (MTS), which often contain missing data. An autoencoder can learn low dimensional vectorial representations of MTS that preserve important data characteristics, but cannot deal explicitly with missing data. In this work, we …
The paper solves a 5-manifold foliation problem using a Sasaki-Ricci flow.
Mathematical method based on a direct or indirect analysis of growth rates is described. It is shown how simple assumptions and a relatively easy analysis can be used to describe mathematically complicated trends and to predict growth. Only rudimentary knowledge of calculus is required. Projected trajectories based on …
We construct families of manifolds that have pairs of genus Heegaard splittings that must be stabilized roughly times to become equivalent. We also show that when two unstabilized, boundary-unstabilized Heegaard splittings are amalgamated by a "sufficiently complicated" map, the resulting splitting is unstabili…
In healthcare applications, temporal variables that encode movement, health status and longitudinal patient evolution are often accompanied by rich structured information such as demographics, diagnostics and medical exam data. However, current methods do not jointly optimize over structured covariates and time series …
Diabetes is a major public health problem in the United States, affecting roughly 30 million people. Diabetes complications, along with the mental health comorbidities that often co-occur with them, are major drivers of high healthcare costs, poor outcomes, and reduced treatment adherence in diabetes. Here, we evaluate…
Let be a 3-manifold with torus boundary components and . Let be a homeomorphism, the manifold obtained from by gluing to via the map , and the image of in . We show that if is "sufficiently complicated" then any incompressible or strongly …
Solar improves variable selection in high-dimensional data with complicated dependence structures.
The theoretical existence of non-classical Schottky groups is due to Marden. Explicit examples of such kind of groups are only known in rank two, the first one by by Yamamoto in 1991 and later by Williams in 2009. In 2006, Maskit and the author provided a theoretical method to obtain examples of non-classical Schottky …
The goal of this paper is to describe a theoretical construction of an infinite collection of non-classical Schottky groups. We first show that there are infinitely many non-classical noded Schottky groups on the boundary of Schottky space, and we show that infinitely many of these are "sufficiently complicated". We th…