Personalized medicine aims at identifying best treatments for a patient with given characteristics. It has been shown in the literature that these methods can lead to great improvements in medicine compared to traditional methods prescribing the same treatment to all patients. Subgroup identification is a branch of per…
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48 results for “subgroup identification”
CAPITAL algorithm identifies optimal patient subgroups for better treatment.
problem Identify maximum number of patients benefiting from better treatment.
method Constrained Policy Tree Search (CAPITAL) algorithm to find optimal subgroup selection rule (SSR).
result Maximizes the number of patients with enhanced treatment effects.
We show that for groups acting acylindrically on simplicial trees the - and -theoretic Farrell-Jones Conjecture relative to the family of subgroups consisting of virtually cyclic subgroups and all subconjugates of vertex stabilisers holds. As an application, for amalgamated free products acting acylindrically on …
Method provides statistical guarantees for identifying subgroups in ML studies.
problem Bias and noise in estimating conditional average treatment effects (CATE).
method Develops uniform confidence bands (GATES) for estimating group average treatment effects (GATEs).
result Identifies subgroups with statistical guarantees, regardless of effect size.
M-learner estimates treatment effects in mediation models with subgroup identification.
problem Estimating heterogeneous treatment effects in mediation models.
method Four-step procedure: compute conditional effects, construct distance matrix, apply tSNE and K-means clustering, refine clusters.
result Validates robustness and effectiveness in real-world dataset.
Causal Interaction Trees identify treatment subgroup effects in observational data.
problem Identifying subgroups with enhanced treatment effects in observational studies.
method Extending Classification and Regression Trees with subgroup-specific treatment effect estimators.
result The proposed algorithms enhance treatment effect heterogeneity in subgroups.
DDGroup identifies subgroups with uniform linear relationships.
problem Heterogeneous effects of covariates in linear models.
method Data-driven method to identify subgroups with uniform linear relationships.
result DDGroup can discover subgroups with improved performance.
MOB-dS uses permutation to correct for dependency in discrete survival data.
problem Identifying subgroups in discrete event time data with potential spurious results.
method Model-based recursive partitioning (MOB) with modified data matrix and permutation test.
result MOB-dS controls type I error rate better than standard MOB for discrete survival data.
Algorithm identifies interpretable subgroups with elevated treatment effects.
problem Estimating high-dimensional, uninterpretable CATE results.
method Rule sets summarizing CATE estimates, optimizing subgroup size and effect size.
result Frontier of Pareto optimal rule sets for subgroup identification.
Adapts to shifts in latent subgroup distributions without labeled target data.
problem Adapting to domain shifts when latent subgroup distributions differ.
method Uses concept and proxy variables from source domain, and unlabeled target data.
result Optimal target predictor can be identified and estimated.
Proposes a new method for subgroup analysis using optimal trees with parameter fusion.
problem Challenges of greedy heuristics and overfitting in tree-based recursive partitioning methods.
method Fused optimal causal tree method leveraging mixed integer optimization (MIO) for globally optimal partitions and parameter fusion.
result Substantial improvement in subgroup discovery accuracy and statistical efficiency.
Cluster analysis methods are used to identify homogeneous subgroups in a data set. In biomedical applications, one frequently applies cluster analysis in order to identify biologically interesting subgroups. In particular, one may wish to identify subgroups that are associated with a particular outcome of interest. Con…
cMCA uses contrastive learning to identify latent subgroups in political party data.
problem Identifying latent subgroups within political party data.
method Contrastive learning applied to multiple correspondence analysis (MCA).
result cMCA identifies latent subgroups not seen by traditional methods.
The identification of predictive biomarkers from a large scale of covariates for subgroup analysis has attracted fundamental attention in medical research. In this article, we propose a generalized penalized regression method with a novel penalty function, for enforcing the hierarchy structure between the prognostic an…
Study adaptive clinical trial methods for identifying patient subpopulations with treatment benefit.
problem Adaptive identification of patient subpopulations with treatment benefit in clinical trials.
method Proposes AdaGGI and AdaGCPI meta-algorithms for subpopulation construction.
result Empirical investigation of AdaGGI and AdaGCPI performance across various simulation scenarios.
We study random walks on groups of isometries of non-proper delta-hyperbolic spaces under the assumption that at least one element in the group satisfies Bestvina-Fujiwara's WPD condition. We show that in this case typical elements are WPD, and the Poisson boundary coincides with the Gromov boundary. Moreover, we show …
Inpatient care is a large share of total health care spending, making analysis of inpatient utilization patterns an important part of understanding what drives health care spending growth. Common features of inpatient utilization measures include zero inflation, over-dispersion, and skewness, all of which complicate st…
New method combines randomization tests and flexible models for valid inference without splitting data.
problem Valid inference in randomized panel experiments with complex effect heterogeneity.
method Model-assisted randomization tests that estimate unsigned CATE from residualized outcomes.
result CATE-assisted tests control Type I error and achieve higher power than alternatives.
A new dynamical approach connects resolution cohomology to group representations.
problem Establishing a bijection between resolution cohomology and group representations.
method Gauge-theoretic Morse flow on the minimal resolution.
result The flow converges to specific irreducible representations of the group.
New method targets relative risk heterogeneity in clinical trials.
problem Identifying treatment effects across subgroups with absolute risk differences.
method Modified causal forests using a novel node-splitting procedure based on relative risk.
result Relative risk causal forests can capture heterogeneity not detected by absolute risk methods.
Contrasting Global and Patient-Specific Regression Models via a Neural Network Representationstat.ME
Proposes a tool to contrast global vs personalized models in clinical prediction.
problem Balancing global vs personalized models in clinical prediction.
method Localized regression approach using autoencoder for dimension reduction.
result Identification of patient subgroups where global models fall short.
We simplify and prove a splitting theorem for mapping class groups of connect sums of .
problem Understanding the structure of mapping class groups of specific 3-manifolds.
method We prove a splitting theorem for the mapping class group of connect sums of , simplifying Laudenbach's original proof.
result The mapping class group of connect sums of is the semidirect product of Out by .
The paper addresses bias in survival analysis due to informative censoring.
problem Bias in treatment effect estimates due to informative censoring in survival analysis.
method Assumption-lean framework using partial identification to derive bounds on CATE.
result Proposes a meta-learner, SurvB-learner, to estimate bounds on CATE.
Given a holomorphic principal bundle , the universal space of holomorphic connections is a torsor for such that the pullback of to has a tautological holomorphic connection. When , where is a parabolic subgroup of a complex simple…
Bayesian Semi-nonnegative Tri-matrix Factorization to Identify Pathways Associated with Cancer Typesstat.ML
Identifying altered pathways that are associated with specific cancer types can potentially bring a significant impact on cancer patient treatment. Accurate identification of such key altered pathways information can be used to develop novel therapeutic agents as well as to understand the molecular mechanisms of variou…
Model predicts higher education dropout risk with interpretable parameters.
problem Predicting and understanding student dropout risk in higher education.
method Sparse interpretable post-clustering logistic regression.
result Model identifies distinct dropout risk subgroups within the student population.
Paper explores using EEG for better speaker identification, even in noisy environments.
problem Speaker identification performance degrades in background noise.
method Uses EEG signals to enhance speaker identification systems, comparing with acoustic features.
result Speaker identification system using only EEG features outperforms one using only acoustic features in high background noise.
In the present paper we study interval identification systems of order three. We prove that the Rauzy induction preserves symmetry: for any symmetric interval identification system of order three after finitely many iterations of the Rauzy induction we always obtain a symmetric system. We also provide an example of sym…
Simplified identification methods for causal inference with arbitrary interventional distributions.
problem Estimating cause-effect relationships from data with experimental interventions.
method Using Single World Intervention Graphs and nested model factorization, we provide algorithms for identifying causal parameters from mixed observational and interventional distributions.
result Our algorithms are complete for certain types of interventional marginal distributions.
Cyclic coordinate descent identifies models in finite time and converges linearly.
problem Model identification in composite nonsmooth optimization problems.
method Cyclic coordinate descent for a wide class of functions.
result Explicit local linear convergence rates for coordinate descent.
Study on identifying and inferring nonlinear dynamics on unknown networks.
problem Identifying network structure in nonlinear dynamic systems with unknown interactions.
method Showed network structure is not generically identified, requiring sufficient spectral heterogeneity. Developed necessary and sufficient conditions for identification and proposed a semiparametric estimator.
result Necessary and sufficient conditions for identification of network structure in nonlinear dynamic systems.
In this paper, we compute the subgroup distortion of all finitely generated subgroups of all finitely generated 3-manifold groups, and the subgroup distortion in this case can only be linear, quadratic, exponential and double exponential. It turns out that the subgroup distortion of a subgroup of a 3-manifold group is …
New findings on complexity limits in fixed budget bandit identification.
problem Determining the best possible error rate for fixed budget bandit identification.
method Analyzing the best non-adaptive sampling procedures and showing the existence of complexities.
result No fixed complexity for certain bandit identification tasks.
On regular subgroups of math.GR
Regular subgroups of SL3(R) are identified and ruled out.
problem Identifying and characterizing regular subgroups of SL3(R).
method Using Kapovich–Leeb–Porti and Guichard–Wienhard divergent subgroups criteria, and Oh's results.
result Regular subgroups of SL3(R) are precisely lattices in minimal horospherical subgroups.
Wi-Fi signals-based person identification attracts increasing attention in the booming Internet-of-Things era mainly due to its pervasiveness and passiveness. Most previous work applies gaits extracted from WiFi distortions caused by the person walking to achieve the identification. However, to extract useful gait, a p…
As one type of efficient unsupervised learning methods, clustering algorithms have been widely used in data mining and knowledge discovery with noticeable advantages. However, clustering algorithms based on density peak have limited clustering effect on data with varying density distribution (VDD), equilibrium distribu…
Study on braid group quotients by congruence subgroups.
problem Understanding the image of congruence subgroups in GL(n,Z).
method Characterization through symplectic congruence subgroups.
result Open problem solved: image of congruence subgroups in GL(n,Z).
The paper explores geometric finiteness in mapping class groups and constructs new examples of these subgroups.
problem Understanding geometric finiteness in mapping class groups and constructing new examples.
method Examined several constructions of subgroups and determined conditions for geometric finiteness.
result Provides new examples of parabolically geometrically finite and reducibly geometrically finite subgroups.
Proposes a new method for finding non-redundant, standout subgroups in numeric datasets.
problem Mining large numbers of redundant subgroups in numeric datasets.
method Dispersion-aware problem formulation based on MDL principle for subgroup set discovery.
result Empirically demonstrates SSD++ returns outstanding subgroup lists.
Congruence Subgroup Property for nilpotent groups and subsurface subgroups of Mapping Class Groupsmath.GR
Proves Congruence Subgroup Property for two types of groups.
problem Proving Congruence Subgroup Property for specific groups.
method Elementary proof of Johnson filtration and geometric subsurface inclusions.
result Proves Congruence Subgroup Property for nilpotent quotients and subsurface subgroups.
New method constructs non-quasiconvex subgroups in hyperbolic groups.
problem Creating non-quasiconvex subgroups in hyperbolic groups.
method Using Stallings-like techniques on right-angled Coxeter groups (RACGs).
result Explicit examples of non-quasiconvex subgroups constructed.
Bayesian methods reduce variance in subspace identification for small data sets.
problem High variance in traditional subspace identification methods for large models or small sample sizes.
method Investigation of Bayesian estimation solutions (regularized and shrinkage estimators) for subspace identification.
result Bayesian estimators reduce estimation risk by up to 40% compared to traditional methods.
On Knotted Subgroupsmath.DG
Characterizes knotted subgroups of Lie groups and provides examples.
problem Defining and understanding knotted subgroups of Lie groups.
method Geometric equivalence, one-parameter subgroups, infinitesimal elements, canonical forms, spectrum analysis.
result Completely classified knotted subgroups of SL(2,R) and SL(3,R).
Subgroups of pro- -groupsmath.GR
Study subgroups of pro- PD^3 groups, finding specific conditions.
problem Characterize subgroups of pro- PD^3 groups.
method Analyzes properties of subnormal and finitely presented subgroups.
result Conditions on subgroups of pro- PD^3 groups.
Driver identification has emerged as a vital research field, where both practitioners and researchers investigate the potential of driver identification to enable a personalized driving experience. Within recent years, a selection of studies have reported that individuals could be perfectly identified based on their dr…
Robust subgroup discovery finds non-redundant, statistically significant subgroups.
problem Finding interpretable, robust subgroups from data.
method Formulated subgroup lists for univariate and multivariate targets, used MDL principle and greedy heuristic SSD++.
result SSD++ outperforms previous methods in quality and size of subgroup lists.
No hyperbolic group can have an infinite chain of free subgroups of fixed rank.
problem Infinite ascending chains of free subgroups in hyperbolic groups.
method Proof by contradiction and properties of hyperbolic groups.
result Hyperbolic groups do not contain strictly ascending chains of free quasiconvex subgroups of constant rank.
A tutorial on non-asymptotic system identification methods.
problem Identifying system parameters in linear models.
method Covering technique, Hanson-Wright Inequality, method of self-normalized martingales.
result Streamlined proofs of least-squares based estimator performance.