A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.
Site-specific recombination is an enzymatic process where two sites of precise sequence and orientation along a circle come together, are cleaved, and the ends are recombined. Site-specific recombination on a knotted substrate produces another knot or a two-component link depending on the relative orientation of the si…
A novel machine learning optimization process coined Restrictive Federated Model Selection (RFMS) is proposed under the scenario, for example, when data from healthcare units can not leave the site it is situated on and it is forbidden to carry out training algorithms on remote data sites due to either technical or pri…
A rational knot or link can be put into a standard alternating format which has horizontal and vertical twist sites (double helices). The number and type of these twist sites are determined by terms of next-to-highest z-degree in Kauffman's regular isotopy invariant Λ(a,z). In particular, for a knot or link with $c…
The research reported in this paper identifies the epigenetic biomarker (methylation beta pattern) of breast cancer. Many cancers are triggered by abnormal gene expression levels caused by aberrant methylation of CpG sites in the DNA. In order to develop early diagnostics of cancer-causing methylations and to develop a…
A site-specific Gordian distance between two spatial embeddings of an abstract graph is the minimal number of crossing changes from one to another where each crossing change is performed between two previously specified abstract edges of the graph. It is infinite in some cases. We determine the site-specific Gordian di…
Owners of a web-site are often interested in analysis of groups of users of their site. Information on these groups can help optimizing the structure and contents of the site. In this paper we use an approach based on formal concepts for constructing taxonomies of user groups. For decreasing the huge amount of concepts…
Site-specific recombination on supercoiled circular DNA molecules can yield a variety of knots and catenanes. Twist knots are some of the most common conformations of these products and they can act as substrates for further rounds of site-specific recombination. They are also one of the simplest families of knots and …
FONT clusters patients across health systems with privacy and efficiency.
problem Challenges in multi-site cluster analysis due to data-sharing restrictions.
method Federated One-shot Ensemble Clustering (FONT) algorithm that requires only a single round of communication and exchanges only fitted model parameters and class labels.
result FONT improves consistency of patient clusters across sites compared to locally fitted clusters.
Connectivity studies using resting-state functional magnetic resonance imaging are increasingly pooling data acquired at multiple sites. While this may allow investigators to speed up recruitment or increase sample size, multisite studies also potentially introduce systematic biases in connectivity measures across site…
RNA-binding proteins (RBPs) play crucial roles in many biological processes, e.g. gene regulation. Computational identification of RBP binding sites on RNAs are urgently needed. In particular, RBPs bind to RNAs by recognizing sequence motifs. Thus, fast locating those motifs on RNA sequences is crucial and time-efficie…
Deep neural network (DNN) has demonstrated its success in multiple domains. However, DNN models are inherently vulnerable to adversarial examples, which are generated by adding adversarial perturbations to benign inputs to fool the DNN model to misclassify. In this paper, we present a cross-layer strategic ensemble fra…
Consequential decision-making typically incentivizes individuals to behave strategically, tailoring their behavior to the specifics of the decision rule. A long line of work has therefore sought to counteract strategic behavior by designing more conservative decision boundaries in an effort to increase robustness to th…
Study one-shot strategic classification under unknown costs, improving worst-case accuracy.
problem Learning robust decision rules in strategic settings with unknown user costs.
method Formal study of one-shot strategic classification, framing as a minimax problem, designing efficient algorithms for full-batch and stochastic settings.
result Proves efficient algorithms converge to minimax solution, revealing dual norm regularization's value.
Consequential decision-making incentivizes individuals to strategically adapt their behavior to the specifics of the decision rule. While a long line of work has viewed strategic adaptation as gaming and attempted to mitigate its effects, recent work has instead sought to design classifiers that incentivize individuals…
We consider a symmetric multi-players zero-sum game with two strategic variables. There are n players, n≥3. Each player is denoted by i. Two strategic variables are ti and si, i∈{1,…,n}. They are related by invertible functions. Using the minimax theorem by \cite{sion} we will show that Nas…
We study a strategic version of the multi-armed bandit problem, where each arm is an individual strategic agent and we, the principal, pull one arm each round. When pulled, the arm receives some private reward va and can choose an amount xa to pass on to the principal (keeping va−xa for itself). All non-pulle…
The results of a learning process depend on the input data. There are cases in which an adversary can strategically tamper with the input data to affect the outcome of the learning process. While some datasets are difficult to attack, many others are susceptible to manipulation. A resourceful attacker can tamper with l…