Paper compares traditional and ML models for renal failure, quantifying bias.
problem Measuring bias in ML models for healthcare applications.
method Compare Tangri risk score with ML model on 1.6M patient data.
result ML model shows better performance and potential bias.
Machine learning improves kidney transplant outcomes prediction.
problem Improving prediction of kidney transplant success.
method Random forest machine learning model trained on kidney donor risk index data.
result Random forest predicted 2,148 more successful transplants than the risk index.
Study uses machine learning and survival analysis to predict CKD progression.
problem Early detection and management of CKD to reduce ESRD risk.
method Combines machine learning and classical statistical models to identify novel CKD progression predictors.
result Deep learning models outperform other methods in predicting CKD progression.
Neural networks promise to bring robust, quantitative analysis to medical fields, but adoption is limited by the technicalities of training these networks. To address this translation gap between medical researchers and neural networks in the field of pathology, we have created an intuitive interface which utilizes the…
Characterization of a patient clinical phenotype is central to biomedical informatics. ICD codes, assigned to inpatient encounters by coders, is important for population health and cohort discovery when clinical information is limited. While ICD codes are assigned to patients by professionals trained and certified in c…
The burgeoning need for kidney transplantation mandates immediate attention. Mismatch of deceased donor-recipient kidney leads to post-transplant death. To ensure ideal kidney donor-recipient match and minimize post-transplant deaths, the paper develops a prediction model that identifies factors that determine the prob…
Kidney function evaluation using dynamic contrast-enhanced MRI (DCE-MRI) images could help in diagnosis and treatment of kidney diseases of children. Automatic segmentation of renal parenchyma is an important step in this process. In this paper, we propose a time and memory efficient fully automated segmentation method…
New fair regression method improves fairness in chronic kidney disease classification.
problem Mitigating societal bias in health care for multiple groups.
method Penalized fair regression framework for multiple groups, with penalties for true positive rate disparity.
result Achieves fairness-accuracy frontier beyond existing methods in simulations and real-world data.
Estimation of response functions is an important task in dynamic medical imaging. This task arises for example in dynamic renal scintigraphy, where impulse response or retention functions are estimated, or in functional magnetic resonance imaging where hemodynamic response functions are required. These functions can no…
RENAL test evaluates generative models for time series data.
problem Evaluating generative models for time series data is challenging.
method RENAL test uses recurrent neural networks to transform time series into conditionally independent data pairs for goodness-of-fit testing.
result RENAL test outperforms existing methods in evaluating generative models for time series data.
Introduction. Case Based Reasoning (CBR) is an emerg- ing decision making paradigm in medical research where new cases are solved relying on previously solved similar cases. Usually, a database of solved cases is provided, and every case is described through a set of attributes (inputs) and a label (output). Extracting…
New CNN architecture improves pediatric image segmentation by homogenizing pose and size.
problem Challenges in segmenting pediatric images due to pose and size heterogeneity.
method Spatial Transformer Network (STN) for pose and scale invariance, combined with UNet for segmentation.
result Improved pediatric segmentation, especially renal tumor delineation, with accelerated processing.
Accurate and robust cell nuclei classification is the cornerstone for a wider range of tasks in digital and Computational Pathology. However, most machine learning systems require extensive labeling from expert pathologists for each individual problem at hand, with no or limited abilities for knowledge transfer between…
Economics tool predicts failure times in reliability systems.
problem Predicting optimal failure times in weighted k-out-of-n reliability systems with heterogeneous component failure.
method Using rational expectations to analyze and predict failure times in reliability systems with heterogeneous component failure.
result Different measures are optimal for predicting system failure depending on component failure distributions.
Although much progress has been made in classification with high-dimensional features \citep{Fan_Fan:2008, JGuo:2010, CaiSun:2014, PRXu:2014}, classification with ultrahigh-dimensional features, wherein the features much outnumber the sample size, defies most existing work. This paper introduces a novel and computation…
Unified model predicts multi-mode failure with multi-sensor data.
problem Independent failure mode and RUL prediction ignores inherent relationship.
method Hierarchical Bayesian framework with Cox model, Gaussian process, and multinomial distributions.
result Robust uncertainty quantification and accurate prediction of multi-mode failure.
Framework classifies machine learning failures into intentional and unintentional.
problem Understanding and preventing failures in machine learning systems.
method Developed a taxonomy of machine learning failure modes.
result Stakeholders found the framework useful for discussing machine learning failures.
GAN-FP uses GANs to predict equipment failures from imbalanced data.
problem Accurately predicting equipment failures with limited data and high imbalance.
method GAN-FP employs two GAN networks to generate and classify imbalanced data, optimizing a weighted loss objective and a consistency GAN.
result GAN-FP outperforms traditional methods in imbalanced failure prediction.
PAGER detects failures in deep regression models using a new framework.
problem Detecting failures in deep regression models.
method PAGER uses a combination of epistemic uncertainty and manifold non-conformity scores.
result PAGER accurately characterizes and detects failures in deep regressors.
Risk Advisor predicts and mitigates ML deployment failures.
problem Predicting and mitigating test-time failure risks of ML systems.
method Post-hoc meta-learner for estimating failure risks and uncertainties.
result Reliably predicts deployment-time failure risks across various ML models.
CalNF models rare failures with limited data, improving safety in autonomous systems.
problem Challenges in modeling and debugging rare safety-critical failures due to limited data.
method CalNF, a self-regularized framework for posterior learning from limited data.
result Achieves state-of-the-art performance on data-limited failure modeling and inverse problems.
We present *K-means clustering algorithm and source code by expanding statistical clustering methods applied in https://ssrn.com/abstract=2802753 to quantitative finance. *K-means is statistically deterministic without specifying initial centers, etc. We apply *K-means to extracting cancer signatures from genome data w…
This work improves safety validation of autonomous vehicles by finding interpretable failures.
problem Finding interpretable failures of autonomous systems in simulation.
method Signal temporal logic expressions optimized for high likelihood and human interpretability.
result Our methodology finds more interpretable failures with higher likelihood compared to baseline approaches.
Framework predicts remaining useful life of DSH subsystems under unknown failure modes.
problem Predicting remaining useful life of DSH subsystems with unknown failure modes.
method Unsupervised framework using mixture of Gaussian regressions and Expectation-Maximization algorithm.
result Improved prediction accuracy and interpretability of RUL.
The paper calculates the likelihood of a financial market failure involving multiple major banks.
problem Estimating the probability of a market failure involving multiple globally important banks.
method Multivariate Cox process across G-SIBs, deriving various theorems on market failure probabilities.
result The probability of a market failure increases with the number of G-SIBs and is inevitable if there are too many.
Paper proposes a method to predict disk failures using multi-layer domain adaptive learning.
problem Traditional machine learning models struggle to predict disk failures due to limited data.
method Multi-layer domain adaptive learning with source and target domains.
result The proposed method improves failure prediction accuracy on disk data with few failure samples.
We aim to predict and explain service failures in supply-chain networks, more precisely among last-mile pickup and delivery services to customers. We analyze a dataset of 500,000 services using (1) supervised classification with Random Forests, and (2) Association Rules. Our classifier reaches an average sensitivity of…
GE finds failures in autonomous systems without domain heuristics.
problem Finding failures in autonomous systems without domain-specific heuristics.
method Adaptive stress testing using go-explore (GE) algorithm.
result GE finds failures in scenarios other RL techniques cannot solve.
Method distinguishes between failures and domain shifts in industrial data streams.
problem Confusing domain shifts with failures in industrial data.
method Modified Page-Hinkley changepoint detector and supervised domain-adaptation-based anomaly detection.
result Allows differentiation between failures and domain shifts.
System predicts respiratory failure up to 8 hours early.
problem Early detection of respiratory failure in ICU patients.
method Machine learning on ICU patient monitoring data.
result System outperforms traditional clinical decision-making.
New method avoids failures in physics-constrained systems using active learning.
problem Handling fatal failures in systems governed by physics constraints.
method Develops a novel active learning method that considers implicit physics constraints.
result Achieves zero-failure in composite fuselage assembly process without explicit failure regions.
This paper addresses the problem of evaluating learning systems in safety critical domains such as autonomous driving, where failures can have catastrophic consequences. We focus on two problems: searching for scenarios when learned agents fail and assessing their probability of failure. The standard method for agent e…
DeepSIP predicts network failures' impact using CNN from syslog and traffic data.
problem Predicting service impact from network failures.
method Temporal multimodal CNN for predicting time to recovery and traffic loss.
result DeepSIP reduced prediction error by approximately 50%.
RODMAN improves ML-based disk failure prediction accuracy in cloud environments.
problem Imperfect data quality in real-world cloud environments degrades ML-based disk failure prediction accuracy.
method RODMAN uses three data preprocessing techniques: failure-type filtering, spline-based data filling, and automated pre-failure backtracking.
result RODMAN significantly improves prediction accuracy compared to no preprocessing.
Two BO methods improve reliability optimization for rare failures.
problem Maximizing reliability of designs subject to random perturbations.
method Bayesian optimization with Thompson sampling and knowledge gradient.
result Proposed methods outperform existing techniques in extreme failure probability scenarios.
New method finds failures in high-fidelity simulators with fewer steps.
problem Finding failures in high-fidelity simulators is expensive and impractical.
method Adaptive stress testing with backward algorithm adaptation from low-fidelity to high-fidelity.
result Significantly fewer high-fidelity simulation steps needed to find failures.
Entropy-based GP adaptive design improves failure probability estimation.
problem Limited accuracy in failure probability estimation due to model evaluation costs.
method Entropy-based Gaussian process (GP) adaptive design combined with multifidelity importance sampling (MFIS).
result More accurate failure probability estimates and higher confidence.
Brain uses synaptic failure to sample from posterior distributions.
problem Bayesian inference in the brain's probabilistic computations.
method Adapting synaptic failure to sample posterior predictive distributions.
result Synaptic failure enables sampling of complete posterior predictive distributions.
Study constructs balanced datasets for seismic failure prediction.
problem Imbalanced datasets limit machine learning performance in seismic failure prediction.
method Framework with three steps: GMF identification, probability density estimation, and sample transformation.
result Framework improves machine learning performance in seismic failure mode prediction.
Proposes a deep neural network for early disk drive failure prediction.
problem Early prediction of disk drive failure using multivariate time series sensor data.
method Enriched features derived from sensor data through transformations, combined with ensemble learning and deep neural network architecture.
result Significantly improved classification accuracy in predicting disk drive failure.
Improves FI-PINNs by combining re-sampling and subset simulation for better failure probability estimation.
problem Estimating failure probability in physics-informed neural networks (PINNs).
method Adaptive sampling with re-sampling and subset simulation, using cosine-annealing for uniform to adaptive transition.
result Significant improvement in estimating failure probability and generating new training points in the failure region.
A new algorithm learns from failures to optimize under constraints efficiently.
problem Optimizing under unknown constraints with limited failure tolerance.
method Excursion search controls risk as a function of a failure budget.
result The algorithm achieves lower regret and uses failures budget more efficiently.
We present a novel method for extracting cancer signatures by applying statistical risk models (http://ssrn.com/abstract=2732453) from quantitative finance to cancer genome data. Using 1389 whole genome sequenced samples from 14 cancers, we identify an "overall" mode of somatic mutational noise. We give a prescription …
Determining possible failure scenarios is a critical step in the evaluation of autonomous vehicle systems. Real-world vehicle testing is commonly employed for autonomous vehicle validation, but the costs and time requirements are high. Consequently, simulation-driven methods such as Adaptive Stress Testing (AST) have b…
New approach uses dynamic programming to efficiently discover failures in autonomous vehicle simulations.
problem Efficiently discovering rare failure events in autonomous vehicle simulations.
method Approximate dynamic programming and scene decomposition to estimate failure distribution.
result Increased number of failures discovered compared to baseline approaches.
Adaptive PINNs improve accuracy by adding points where solutions are uncertain.
problem Inadequate sampling in PINNs leads to inaccurate solutions, especially near singularities.
method FI-PINNs use failure probability to dynamically add points, improving numerical accuracy.
result FI-PINNs achieve better accuracy through adaptive sampling, as proven by rigorous error bounds.
Bayesian inference models failure distributions in autonomous systems.
problem Estimating the distribution of failures in complex systems.
method Bayesian inference using system dynamics rollouts and gradient computation.
result Improves sample efficiency and parameter space coverage in autonomous systems.
We develop a new method to estimate failure probabilities in complex systems.
problem Estimating failure probabilities in safety-critical autonomous systems is challenging due to the rarity of failures and large state spaces.
method We propose an adaptive importance sampling algorithm that minimizes forward Kullback-Leibler divergence and uses Markov score ascent methods.
result Our method provides more accurate failure probability estimates than existing techniques.