Measures regulatory activity and complexity over 23 years.
problem Lack of large-scale, longitudinal data on regulatory activity and complexity.
method Analyzed over 4.5 million references to U.S. Federal Acts and Agencies in Form 10-Ks.
result Regulatory energy per filing (temperature) and diversity have increased over 23 years.
TNDE quantifies dynamic gene drivers from single-cell snapshots.
problem Reconstructing time-resolved regulatory effects in biological processes.
method Time-varying Network Driver Estimation (TNDE) using shared graph attention encoder and partial optimal transport.
result TNDE identifies stage-specific driver genes in mouse erythropoiesis.
Paper develops a framework to discover bioprocessing regulatory mechanisms using symbolic and statistical learning.
problem Challenges in modeling complex intracellular regulation, stochastic system behavior, and limited experimental data.
method Symbolic and statistical learning framework based on stochastic differential equations and Bayesian learning.
result Improved sample efficiency and robust model selection compared to state-of-the-art approaches.
A financial data provider shares insights on managing complexity in processing 18 billion daily notifications.
problem Managing complexity in processing 18 billion daily financial notifications.
method Described the volume, variety, velocity, and veracity of data, infrastructure, and architecture.
result Systems were stressed during significant events like Brexit, highlighting the need for scalability and robustness.
RECON reconstructs regulatory networks from time-course data, reducing spurious edges and preserving true regulatory edges.
problem Reconstructing regulatory networks from time-course data with minimal spurious edges and preserving true regulatory relationships.
method RECON uses an integral-based additive nonparametric ODE model with five methodological advances to reconstruct regulatory networks.
result RECON consistently outperforms existing methods, reducing spurious edges and preserving true regulatory edges across various scenarios.
Within the Own Risk and Solvency Assessment framework, the Solvency II directive introduces the need for insurance undertakings to have efficient tools enabling the companies to assess the continuous compliance with regulatory solvency requirements. Because of the great operational complexity resulting from each comple…
This paper examines market misconduct in DeFi and proposes regulatory solutions.
problem Novel forms of market misconduct in DeFi.
method Comprehensive analysis, comparative study, empirical measurements, and tailored regulatory framework investigation.
result Identification of key areas for regulatory enhancement in DeFi.
Monotonic neural additive models simplify machine learning for credit scoring.
problem Complex machine learning methods make models less transparent and fair.
method Introducing monotonic neural additive models that simplify neural networks while maintaining regulatory compliance.
result Monotonic neural additive models achieve similar accuracy to complex neural networks but are more transparent and fair.
This research assesses uncertainty quantification and sensitivity analysis for DTs in nuclear fuel performance.
problem Understanding the reliability and performance of advanced nuclear fuels using DTs.
method Introduces ML-based uncertainty quantification and sensitivity analysis methods applied to BISON fuel performance code.
result Demonstrates the effectiveness of DTs in multi-criteria decision-making for nuclear fuel performance.
regvis.net offers a visual survey of regulatory visualization.
problem Lack of a comprehensive resource for regulatory visualization.
method Collection and manual tagging of 80+ publications, creation of a searchable webpage.
result First publication set tailored for regulatory visualization.
Optimizes insurance profits under regulatory constraints.
problem Maximizing profits while adhering to regulatory and risk policies.
method Developed a formalism for in-force business profit optimisation.
result Identified optimal asset allocation and annual opportunity cost.
Study uses LLMs to simplify financial regulation interpretation.
problem Complex financial regulations are hard to interpret and implement.
method Developed prompts to guide LLMs in extracting key information from regulations.
result GPT-4 outperforms other LLMs in processing and executing regulatory requirements.
Dynamic model considers private asset markets' complexities.
problem Understanding and optimizing private asset allocation.
method State-of-the-art dynamic model with machine learning.
result Optimal investment policies quantified over fund life.
Bayesian method infers gene regulatory network structure from data.
problem Discovering local causal relationships in gene regulatory networks.
method Bayesian approach scoring covariance patterns with background priors.
result Stable and conservative posterior estimates of regulatory relationships.
Paper introduces RiskEmbed, a finetuned model for financial risk management.
problem Improving retrieval accuracy in financial question-answering systems.
method Curated dataset and finetuned BERT model for financial domain.
result RiskEmbed significantly outperforms general-purpose and financial embedding models.
The paper develops a scalable method to infer GRNs from sparse data.
problem Inferring complex gene regulatory networks from limited and temporally sparse data.
method Bayesian optimization and kernel-based methods to construct a Gaussian Process (GP) model.
result The method efficiently searches for the topology with the highest likelihood value.
Study efficient auditing of ML fairness models.
problem Scalability of auditing ML models for fairness.
method Query-based auditing algorithms for estimating demographic parity.
result Optimal deterministic and practical randomized algorithms for fairness estimation.
LexNLP processes legal and regulatory texts for structured information.
problem Processing structured information from legal and regulatory texts.
method Natural language processing and machine learning for legal and regulatory text.
result LexNLP extracts over eighteen types of structured information from legal and regulatory texts.
In a market system, regulations are designed to prevent or rectify market failures that inhibit fair exchange, such as monopoly or transactions with hidden costs. Because regulations reduce profits to those possessing unfair advantage, these advantaged corporations (whether individuals, companies, or other collective o…
New method infers causal factors from large-scale data without full graph reconstruction.
problem Inferring causal variables from large-scale systems without full causal graph reconstruction.
method Supervised learning on simulated data using a neural network and subsampled-ensemble inference.
result Efficiently identifies causal relationships in large-scale gene regulatory networks.
System tracks regulatory changes for compliance officers.
problem Struggling to keep up with regulatory changes.
method Fetch announcements, classify importance and applicability.
result Simple hierarchical classification works best.
This review analyzes RL in finance, highlighting its advantages and challenges.
problem Complex financial decision-making problems where traditional methods fail.
method Systematic review of 167 articles from 2017-2025, focusing on market making, portfolio optimization, and algorithmic trading.
result RL offers advantages over traditional methods, particularly in market making, but challenges remain.
Bayesian method discovers local causal relationships among genes from gene expression data.
problem Discovering gene regulatory relationships from gene expression data.
method Bayesian approach scoring covariance structures for triplets of normally distributed variables, incorporating background knowledge as priors.
result Stable and conservative posterior probability estimates of local causal structures.
Paper constructs a CRRIX index to assess cryptocurrency market risks from regulatory changes.
problem Lack of indices quantifying regulatory risks in cryptocurrencies.
method CRRIX index based on news coverage frequency, using Latent Dirichlet Allocation and Hellinger distance.
result CRRIX successfully captures major policy-changing moments and synchronizes with market volatility.
In November, 2011, the Financial Stability Board, in collaboration with the International Monetary Fund, published a list of 29 "systemically important financial institutions" (SIFIs). This designation reflects a concern that the failure of any one of them could have dramatic negative consequences for the global econom…
InfoSEM infers gene regulatory networks without GT labels, improving performance.
problem Inferring GRNs from gene expression data with high accuracy and avoiding biases.
method InfoSEM uses deep generative models with informative priors (textual gene embeddings).
result InfoSEM outperforms existing models by 38.5% across four datasets.
New method constructs confidence bands for ODE models with unknown regulatory effects.
problem Building confidence bands for ODE models with unknown regulatory relations is challenging.
method Localized kernel learning approach combined with de-biasing method.
result The constructed confidence band has the desired asymptotic coverage probability and accurately recovers the regulatory network.
Do we know if a short selling ban or a Tobin Tax result in more stable asset prices? Or do they in fact make things worse? Just like medicine regulatory measures in financial markets aim at improving an already complex system. And just like medicine these interventions can cause side effects which are even harder to as…
Proposes a new method for determining LGD discount rates based on cost of capital.
problem Determining an appropriate discount rate for LGD estimation.
method Market-consistent pricing of defaulted loan portfolios to infer discount rates.
result Discount rates reflect both undiversifiable risk and time value of money.
Funding is a cost to trading desks that they see as an input. Current FVA-related literature reflects this by also taking funding costs as an input, usually constant, and always risk-neutral. However, this funding curve is the output from a Treasury point of view. Treasury must consider Regulatory-required liquidity bu…
NO-BEARS algorithm speeds up gene network inference from transcriptomic data.
problem Constructing accurate gene regulatory networks from transcriptomic data.
method NO-BEARS algorithm, based on NOTEARS, with new constraint and polynomial regression loss.
result Significantly reduced computational time and improved accuracy in inferring gene regulatory networks.
Optimal trading and liquidation strategies with signals and regulatory constraints.
problem Optimal trading and liquidation in models with price predictions and regulatory limits.
method Almgren-Chriss model with general signals, target zone models, and lookback option analysis.
result Explicit formulas for optimal liquidation rates in Bachelier and Black-Scholes dynamics.
Simple method calculates WWR for regulatory and accounting purposes.
problem Estimating WWR for regulatory and accounting capital requirements.
method Model-independent approach using integral expressions and component calibration.
result WWR effects for FVA are significantly more material than for CVA.
DASH simplifies neural networks for gene regulatory dynamics using domain knowledge.
problem Pruning neural networks for gene regulatory dynamics lacks biologically meaningful structure learning.
method DASH uses domain-specific structural information to guide network pruning, leading to sparser, better interpretable models.
result DASH outperforms general pruning methods in gene regulatory network inference, yielding deeper insights.
Bayesian model learns cell types and gene networks from two data views.
problem Estimating cell types and their regulatory networks from single-cell gene expression and epigenetic data.
method Symphony Bayesian hierarchical multi-view mixture model with Variational EM inference.
result Symphony outperforms other methods in learning cell types and regulatory networks.
Cryptocurrency markets show similar returns but different volatility responses to infrastructure and regulatory shocks.
problem Understanding how cryptocurrency markets differentiate between infrastructure and regulatory shocks.
method Event-level block bootstrap inference on 31 cryptocurrency events across Bitcoin, Ethereum, Solana, and Cardano (2019-2025).
result No statistically significant difference in cumulative abnormal returns between infrastructure failures and regulatory enforcement.
Complex financial networks with CDSs make clearing after shocks NP-complete.
problem Computing solutions for financial networks with CDSs after shocks.
method Computational complexity theory applied to financial network clearing.
result Clearing financial networks with CDSs is NP-complete.
New framework for adaptive clinical trials to address real-world challenges.
problem Real-world challenges in post-regulatory clinical trials.
method RFAN framework integrating regulatory constraints and treatment policy value.
result Empirical evaluation of RFAN's performance.
Efficiently infers gene regulatory networks from spatial data.
problem Inferring spatially-varying gene regulatory networks.
method Proposed an efficient optimization problem for SV-GMRFs.
result Solves large-scale SV-GMRF problems in minutes.
The paper tackles controlling gene regulatory networks with noisy measurements and uncertain inputs.
problem Controlling gene regulatory networks with indirect measurements and uncertain inputs.
method Modeling GRNs with POBDS, transforming to a Markov Decision Process, using Gaussian processes for cost function, and applying reinforcement learning and sparsification.
result Near-optimal control strategy for infinite-horizon control of GRNs is found.
SHARC explains machine learning risk models for regulatory capital, linking outputs to scenarios.
problem Inability to explain machine learning model outputs to regulatory bodies.
method SHAP-based explainability framework for Hybrid GPR-HS architecture and SVaR stress-testing.
result SHARC links SVaR outputs to scenario inputs, providing auditable traceability.
Robust machine learning models improve DNA regulatory sequence prediction under various shifts.
problem Real-world applications of DNA regulatory sequence prediction involve shifts not captured by standard i.i.d. assumptions.
method Introduces a robustness framework combining simulation benchmarks and real data analysis.
result Models remain accurate and calibrated under mild shifts but show higher error and miscalibration under strong shifts.
Develops probabilistic models for gene regulatory network inference.
problem Challenges in reconstructing gene regulatory networks from genome-wide data.
method Two complementary frameworks: PMF-GRN and GLM-Prior.
result Probabilistic inference refines regulatory estimates with quantified uncertainty.
Study examines how business units can benefit from group cohesion under regulatory constraints.
problem Regulatory constraints limit business units' ability to form a single cohesive group.
method Defined and analyzed cohesive risk measures to minimize capital costs.
result Cohesive risk measures allow groups to achieve minimal capital costs without altering individual liabilities.
Study analyzes FIT schemes under market and regulatory uncertainty.
problem Tackles uncertainty in feed-in tariffs and their impact on investment thresholds.
method Uses semi-analytical real options framework to model and compare FIT schemes.
result Increasing regulatory uncertainty lowers investment thresholds for FIT schemes.
The DAO Report led to a significant shift of ICO activity to Europe.
problem The impact of U.S. regulatory changes on global ICO activity.
method Analysis of a global dataset of ICOs from 2014 to 2021, focusing on the DAO Report's effects.
result A substantial and persistent reallocation of ICO activity to Europe following the DAO Report.
Paper proposes a new topology for AML analysis using Poincaré embeddings.
problem Complex money laundering schemes and regulatory constraints hinder AML analysis and information sharing.
method Proposes a new topology for AML analysis using Poincaré embeddings.
result Demonstrates improved AML analysis and information sharing through Poincaré embeddings.
Machine learning identifies key metabolic control circuits in bacterial pathways.
problem Identifying regulated metabolic pathways in bacteria.
method Machine learning approach analyzing multi-omics data.
result Identification of E. coli Glycolysis regulatory circuits.