Over the last 23 years, the U.S. Securities and Exchange Commission has required over 34,000 companies to file over 165,000 annual reports. These reports, the so-called "Form 10-Ks," contain a characterization of a company's financial performance and its risks, including the regulatory environment in which a company op…
This paper examines market misconduct in DeFi and proposes regulatory solutions.
problem Novel forms of market misconduct in DeFi.
method Comprehensive analysis, comparative study, empirical measurements, and tailored regulatory framework investigation.
result Identification of key areas for regulatory enhancement in DeFi.
Paper develops a framework to discover bioprocessing regulatory mechanisms using symbolic and statistical learning.
problem Challenges in modeling complex intracellular regulation, stochastic system behavior, and limited experimental data.
method Symbolic and statistical learning framework based on stochastic differential equations and Bayesian learning.
result Improved sample efficiency and robust model selection compared to state-of-the-art approaches.
regvis.net offers a visual survey of regulatory visualization.
problem Lack of a comprehensive resource for regulatory visualization.
method Collection and manual tagging of 80+ publications, creation of a searchable webpage.
result First publication set tailored for regulatory visualization.
Optimizes insurance profits under regulatory constraints.
problem Maximizing profits while adhering to regulatory and risk policies.
method Developed a formalism for in-force business profit optimisation.
result Identified optimal asset allocation and annual opportunity cost.
TNDE quantifies dynamic gene drivers from single-cell snapshots.
problem Reconstructing time-resolved regulatory effects in biological processes.
method Time-varying Network Driver Estimation (TNDE) using shared graph attention encoder and partial optimal transport.
result TNDE identifies stage-specific driver genes in mouse erythropoiesis.
In a market system, regulations are designed to prevent or rectify market failures that inhibit fair exchange, such as monopoly or transactions with hidden costs. Because regulations reduce profits to those possessing unfair advantage, these advantaged corporations (whether individuals, companies, or other collective o…
Paper constructs a CRRIX index to assess cryptocurrency market risks from regulatory changes.
problem Lack of indices quantifying regulatory risks in cryptocurrencies.
method CRRIX index based on news coverage frequency, using Latent Dirichlet Allocation and Hellinger distance.
result CRRIX successfully captures major policy-changing moments and synchronizes with market volatility.
InfoSEM infers gene regulatory networks without GT labels, improving performance.
problem Inferring GRNs from gene expression data with high accuracy and avoiding biases.
method InfoSEM uses deep generative models with informative priors (textual gene embeddings).
result InfoSEM outperforms existing models by 38.5% across four datasets.
New method constructs confidence bands for ODE models with unknown regulatory effects.
problem Building confidence bands for ODE models with unknown regulatory relations is challenging.
method Localized kernel learning approach combined with de-biasing method.
result The constructed confidence band has the desired asymptotic coverage probability and accurately recovers the regulatory network.
Proposes a new method for determining LGD discount rates based on cost of capital.
problem Determining an appropriate discount rate for LGD estimation.
method Market-consistent pricing of defaulted loan portfolios to infer discount rates.
result Discount rates reflect both undiversifiable risk and time value of money.
Gene regulatory networks play a crucial role in controlling an organism's biological processes, which is why there is significant interest in developing computational methods that are able to extract their structure from high-throughput genetic data. Many of these computational methods are designed to infer individual …
Funding is a cost to trading desks that they see as an input. Current FVA-related literature reflects this by also taking funding costs as an input, usually constant, and always risk-neutral. However, this funding curve is the output from a Treasury point of view. Treasury must consider Regulatory-required liquidity bu…
Simple method calculates WWR for regulatory and accounting purposes.
problem Estimating WWR for regulatory and accounting capital requirements.
method Model-independent approach using integral expressions and component calibration.
result WWR effects for FVA are significantly more material than for CVA.
DASH simplifies neural networks for gene regulatory dynamics using domain knowledge.
problem Pruning neural networks for gene regulatory dynamics lacks biologically meaningful structure learning.
method DASH uses domain-specific structural information to guide network pruning, leading to sparser, better interpretable models.
result DASH outperforms general pruning methods in gene regulatory network inference, yielding deeper insights.
Gene regulatory networks play a crucial role in controlling an organism's biological processes, which is why there is significant interest in developing computational methods that are able to extract their structure from high-throughput genetic data. A typical approach consists of a series of conditional independence t…
Cryptocurrency markets show similar returns but different volatility responses to infrastructure and regulatory shocks.
problem Understanding how cryptocurrency markets differentiate between infrastructure and regulatory shocks.
method Event-level block bootstrap inference on 31 cryptocurrency events across Bitcoin, Ethereum, Solana, and Cardano (2019-2025).
result No statistically significant difference in cumulative abnormal returns between infrastructure failures and regulatory enforcement.
New framework for adaptive clinical trials to address real-world challenges.
problem Real-world challenges in post-regulatory clinical trials.
method RFAN framework integrating regulatory constraints and treatment policy value.
result Empirical evaluation of RFAN's performance.
Efficiently infers gene regulatory networks from spatial data.
problem Inferring spatially-varying gene regulatory networks.
method Proposed an efficient optimization problem for SV-GMRFs.
result Solves large-scale SV-GMRF problems in minutes.
SHARC explains machine learning risk models for regulatory capital, linking outputs to scenarios.
problem Inability to explain machine learning model outputs to regulatory bodies.
method SHAP-based explainability framework for Hybrid GPR-HS architecture and SVaR stress-testing.
result SHARC links SVaR outputs to scenario inputs, providing auditable traceability.
Robust machine learning models improve DNA regulatory sequence prediction under various shifts.
problem Real-world applications of DNA regulatory sequence prediction involve shifts not captured by standard i.i.d. assumptions.
method Introduces a robustness framework combining simulation benchmarks and real data analysis.
result Models remain accurate and calibrated under mild shifts but show higher error and miscalibration under strong shifts.
Develops probabilistic models for gene regulatory network inference.
problem Challenges in reconstructing gene regulatory networks from genome-wide data.
method Two complementary frameworks: PMF-GRN and GLM-Prior.
result Probabilistic inference refines regulatory estimates with quantified uncertainty.
Study examines how business units can benefit from group cohesion under regulatory constraints.
problem Regulatory constraints limit business units' ability to form a single cohesive group.
method Defined and analyzed cohesive risk measures to minimize capital costs.
result Cohesive risk measures allow groups to achieve minimal capital costs without altering individual liabilities.
The DAO Report led to a significant shift of ICO activity to Europe.
problem The impact of U.S. regulatory changes on global ICO activity.
method Analysis of a global dataset of ICOs from 2014 to 2021, focusing on the DAO Report's effects.
result A substantial and persistent reallocation of ICO activity to Europe following the DAO Report.
Constructing gene regulatory networks is a critical step in revealing disease mechanisms from transcriptomic data. In this work, we present NO-BEARS, a novel algorithm for estimating gene regulatory networks. The NO-BEARS algorithm is built on the basis of the NOTEARS algorithm with two improvements. First, we propose …
Reconstructing transcriptional regulatory networks is an important task in functional genomics. Data obtained from experiments that perturb genes by knockouts or RNA interference contain useful information for addressing this reconstruction problem. However, such data can be limited in size and/or are expensive to acqu…
Model predicts trade volume changes from financial filings.
problem Improving financial market understanding through machine learning.
method Hierarchical Reformer model trained on SEDAR filings.
result Model can predict trade volume changes without explicit training.
Regulations impose idiosyncratic capital and funding costs for holding derivatives. Capital requirements are costly because derivatives desks are risky businesses; funding is costly in part because regulations increase the minimum funding tenor. Idiosyncratic costs mean no single measure makes derivatives martingales f…
We present a Bayesian hierarchical multi-view mixture model termed Symphony that simultaneously learns clusters of cells representing cell types and their underlying gene regulatory networks by integrating data from two views: single-cell gene expression data and paired epigenetic data, which is informative of gene-gen…
FinDiff generates synthetic financial data for regulatory tasks.
problem Sharing microdata for research due to privacy regulations.
method Diffusion model using embedding encodings for mixed modality financial data.
result FinDiff excels in generating high-fidelity, privacy-preserving synthetic financial data.
New framework makes ML methods compliant with regulations.
problem Ensuring ML methods meet regulatory standards.
method InfoGram and Admissible Machine Learning framework.
result Redesigns ML methods for regulatory compliance.
In 1999 Robert Fernholz observed an inconsistency between the normative assumption of existence of an equivalent martingale measure (EMM) and the empirical reality of diversity in equity markets. We explore a method of imposing diversity on market models by a type of antitrust regulation that is compatible with EMMs. T…
Regulatory compliance is an organization's adherence to laws, regulations, guidelines and specifications relevant to its business. Compliance officers responsible for maintaining adherence constantly struggle to keep up with the large amount of changes in regulatory requirements. Keeping up with the changes entail two …
RSI uses Bayesian inference to monitor compliance in rule-governed domains.
problem Structural obstacles in compliance monitoring, including unlabeled outcomes and selective withholding of evidence.
method Rule-State Inference (RSI) treats formalized rules as Bayesian priors and infers compliance states through mean-field variational inference.
result RSI delivers formal guarantees of adaptability, consistency, and convergence, validated on a synthetic enterprise benchmark.
LexNLP is an open source Python package focused on natural language processing and machine learning for legal and regulatory text. The package includes functionality to (i) segment documents, (ii) identify key text such as titles and section headings, (iii) extract over eighteen types of structured information like dis…
Regshock visualizes financial risks to help regulators manage systemic shocks.
problem Managing systemic risks in financial networks.
method Risk-island visualization algorithm and regshock visual exploration approach.
result Demonstrated improved risk management and control capabilities.
The paper analyzes how leverage affects manipulation in event-linked markets, offering new insights into regulation.
problem Manipulation and insider information in leveraged event-linked markets.
method Develops a two-axis manipulation taxonomy and analyzes leverage's effects on market-price and outcome manipulation.
result Leverage scales market-price manipulation linearly but shifts the cost-benefit threshold for outcome manipulation.
This paper improves operational risk modeling by selecting better loss severity distributions.
problem Inconsistent regulatory capital calculations due to changing loss severity distribution families.
method Presented truncation probability estimates and a consistent quantile scoring function for selection criteria. Also, recommended collecting loss frequencies below the minimum reporting threshold.
result More stable regulatory capital calculations through better selection of loss severity distributions.
Accounting fraud is a global concern representing a significant threat to the financial system stability due to the resulting diminishing of the market confidence and trust of regulatory authorities. Several tricks can be used to commit accounting fraud, hence the need for non-static regulatory interventions that take …
Monotonic neural additive models simplify machine learning for credit scoring.
problem Complex machine learning methods make models less transparent and fair.
method Introducing monotonic neural additive models that simplify neural networks while maintaining regulatory compliance.
result Monotonic neural additive models achieve similar accuracy to complex neural networks but are more transparent and fair.
SEISM tests neural network features for regulatory genomics.
problem Testing neural network features for regulatory genomics.
method Selective inference procedure for sequence motifs.
result Sampling under specific parameters characterizes composite null hypothesis.
Research creates a taxonomy to bridge AI security and regulatory gaps.
problem Disciplinary disconnect between technical and legal teams in AI risk assessment.
method Developed an AI System Threat Vector Taxonomy with 9 domains and 53 sub-threats.
result Empirically validated and aligned with ISO/IEC 42001 controls and NIST AI RMF functions.
Study shows how capital constraints can lead to systemic crises in financial systems.
problem Impact of regulatory capital constraints on fire sales and financial stability.
method Mean field game model with banks adjusting holdings via trading strategies under regulatory constraints.
result Capital constraints can lead to simultaneous defaults in a substantial proportion of the banking system.
Regulating crypto and DeFi for inclusive economic advancement.
problem Innovative financial systems pose challenges to traditional regulatory frameworks.
method Formulating regulatory structures that balance innovation and consumer protection.
result Regulatory frameworks are essential for leveraging crypto and DeFi for inclusive economic growth.
In this work, a machine learning approach for identifying the multi-omics metabolic regulatory control circuits inside the pathways is described. Therefore, the identification of bacterial metabolic pathways that are more regulated than others in term of their multi-omics follows from the analysis of these circuits . T…
Algorithm recovers large causal tree from small samples.
problem Determining causal structure in large gene networks.
method Algorithm that recovers tree with high accuracy under mild conditions.
result High accuracy in recovering causal tree from small samples.
This paper examines if CTE risk measure aligns with profit-maximizing risk capital allocations.
problem Whether CTE risk measure aligns with profit-maximizing risk capital allocations.
method Exhaustive probabilistic model settings analysis.
result CTE risk measure may align with profit-maximizing risk capital allocations under certain conditions.
Study shows ethanol blends and incentives can significantly reduce transportation carbon emissions.
problem Rapid growth in electric vehicles requires complementary strategies to decarbonize transportation.
method Analysis of ethanol blending, regulatory incentives, and economic assessments.
result Ethanol blending, especially E15 and E85, can substantially reduce carbon emissions and provide economic benefits.