Markov chain Monte Carlo (MCMC) algorithms for hidden Markov models often rely on the forward-backward sampler. This makes them computationally slow as the length of the time series increases, motivating the development of sub-sampling-based approaches. These approximate the full posterior by using small random subsequ…
New method learns diffusion bridges for rare events.
problem Simulating rare events in diffusion processes.
method Iterative online learning based on self-consistency.
result Strong performance in various empirical settings.
Enhanced diffusion sampling improves rare event sampling in biomolecular simulations.
problem Efficiently sampling rare transition events in biomolecular systems.
method Quantitative steering protocols to generate biased ensembles and exact reweighting.
result Fast, accurate, and scalable estimation of equilibrium properties.
Enhanced diffusion sampling tackles rare event sampling in biomolecular simulations.
problem Efficiently sampling rare transition events in biomolecular simulations.
method Quantitative steering protocols to generate biased ensembles, followed by exact reweighting.
result Fast, accurate, and scalable estimation of equilibrium properties for folding free energies.
Develops methods to simulate rare transitions in molecular systems.
problem Rare transitions between metastable states in molecular systems are difficult to study due to limited data.
method Two novel methods: chain-based and midpoint-based approaches.
result Demonstrates effectiveness of methods in both data-rich and data-scarce scenarios.
Given a labeled dataset that contains a rare (or minority) class of of-interest instances, as well as a large class of instances that are not of interest, how can we learn to recognize future of-interest instances over a continuous stream? We introduce RaRecognize, which (i) estimates a general decision boundary betwee…
New test uncovers causal links in rare event dynamics.
problem Causal discovery for rare event phenomena in dynamic systems.
method Nonparametric conditional independence test on time-invariant data.
result Validated across simulated and real-world datasets.
The committor function is a central object of study in understanding transitions between metastable states in complex systems. However, computing the committor function for realistic systems at low temperatures is a challenging task, due to the curse of dimensionality and the scarcity of transition data. In this paper,…
A new method uses deep learning to efficiently sample rare transitions for estimating committor functions.
problem Efficiently sampling rare transitions to estimate committor functions in high-dimensional problems.
method DASTR (Deep Adaptive Sampling on Transition Paths) method using deep generative models.
result Significantly improved accuracy in approximating committor functions through efficient sampling.
New method uses active importance sampling for rare event optimization in high-dimensional problems.
problem Optimizing complex, high-dimensional functions with rare events.
method Combines rare events sampling with neural network optimization.
result Importance sampling reduces asymptotic variance, improving generalization.
New method improves reinforcement learning generalization.
problem Few environments lead to poor generalization in reinforcement learning.
method Integrates sequential structure into representation learning, using a policy similarity metric (PSM) and contrastive embeddings (PSEs).
result PSEs improve generalization across various benchmarks.
TRAKNN detects rare atmospheric trajectories efficiently.
problem Detecting rare atmospheric anomalies over long periods.
method Unsupervised, recurrence-based kNN algorithm.
result Rare trajectories correspond to physical anomalies.
MIM-based GAN improves rare event generation in GANs.
problem Improving rare event generation in GANs.
method Adopting MIM (exponential form of information metric) to replace KL divergence in GANs.
result MIM-based GAN achieves state-of-the-art performance in anomaly detection.
Jeffreys Flow improves robustness of Boltzmann generators for rare event sampling.
problem Rare events and metastable trapping in sampling physical systems with rough energy landscapes.
method Introduces Jeffreys Flow, a robust generative framework using Parallel Tempering distillation and symmetric Jeffreys divergence to mitigate mode collapse and improve mode coverage.
result Minimizing Jeffreys divergence suppresses mode collapse and corrects inaccuracies in multi-modal distributions.
In this work, we present our various contributions to the objective of building a decision support tool for the diagnosis of rare diseases. Our goal is to achieve a state of knowledge where the uncertainty about the patient's disease is below a predetermined threshold. We aim to reach such states while minimizing the a…
A framework to quantify deployment risk in ML systems, especially for rare states.
problem Under-supported rare states in ML models lead to unreliable performance in unseen data.
method Blind-Spot Mass (B_n(tau)) using Good-Turing unseen-species estimation.
result Identifies and quantifies the risk of under-supported states in ML models.
A new method estimates rare failure events in complex systems.
problem Estimating the probability of rare failure events in non-linear systems.
method Stochastic Spectral Embedding (SSE) combined with modifications for efficient rare event estimation.
result Rare failure probability decomposed into conditional probabilities for easier computation.
Use of an autoencoder (AE) as a normal model is a state-of-the-art technique for unsupervised-anomaly detection in sounds (ADS). The AE is trained to minimize the sample mean of the anomaly score of normal sounds in a mini-batch. One problem with this approach is that the anomaly score of rare-normal sounds becomes hig…
This paper shows that one cannot learn the probability of rare events without imposing further structural assumptions. The event of interest is that of obtaining an outcome outside the coverage of an i.i.d. sample from a discrete distribution. The probability of this event is referred to as the "missing mass". The impo…
It is common in modern prediction problems for many predictor variables to be counts of rarely occurring events. This leads to design matrices in which many columns are highly sparse. The challenge posed by such "rare features" has received little attention despite its prevalence in diverse areas, ranging from natural …
We develop importance sampling based efficient simulation techniques for three commonly encountered rare event probabilities associated with random walks having i.i.d. regularly varying increments; namely, 1) the large deviation probabilities, 2) the level crossing probabilities, and 3) the level crossing probabilities…
Generative model simulates rare events for better decision making.
problem Rare events impact decision making but are hard to sample.
method Normalizing Flow coupled with Importance Sampling.
result Accurate estimation of rare events improves decision outcomes.
AI boosts study of rare weather extremes with lower costs.
problem Difficulty in studying rare weather events due to limited data and models.
method Coupling AI forecasts with physics models using rare-event algorithms.
result Efficiently characterizes very rare events like once-per-millennium heatwaves.
CalNF models rare failures with limited data, improving safety in autonomous systems.
problem Challenges in modeling and debugging rare safety-critical failures due to limited data.
method CalNF, a self-regularized framework for posterior learning from limited data.
result Achieves state-of-the-art performance on data-limited failure modeling and inverse problems.
Rare diseases affecting 350 million individuals are commonly associated with delay in diagnosis or misdiagnosis. To improve those patients' outcome, rare disease detection is an important task for identifying patients with rare conditions based on longitudinal medical claims. In this paper, we present a deep learning m…
Unified framework for growth models with environmental risk and pollution-dependent disasters.
problem Analyzing how rare but catastrophic shocks interact with capital accumulation and pollution in stochastic growth models.
method General Poisson point process formulation leading to non-local HJB equations with closed-form solutions.
result Unified framework captures how environmental degradation amplifies macroeconomic vulnerability and strengthens incentives for abatement.
Develops a method to estimate rare-event probabilities under distributional uncertainty.
problem Distributional uncertainty limits the effectiveness of rare-event simulation techniques.
method Wasserstein distributionally robust rare-event simulation (DRIS) framework.
result DRIS achieves vanishing relative error in estimating rare-event probabilities.
Reduces false positives in classifying rare online platforms.
problem Challenges in accurately identifying rare online platforms with ML.
method Calibrated probabilities and ensembles to reduce bias.
result Significantly reduces false positives in rare event detection.
This paper evaluates data enrichment techniques for rare event detection in manufacturing.
problem Rare events in manufacturing lead to unplanned downtime and high energy consumption.
method Time series data augmentation, sampling, and imputation techniques combined with supervised machine learning.
result Data enrichment enhances rare failure event detection and prediction by up to 48%.
A new framework uses stochastic optimal control to estimate rare events more accurately.
problem Estimating rare events like chemical reactions in biomolecules is computationally challenging.
method The approach casts committor estimation as a stochastic optimal control problem, developing direct and off-policy Value Matching losses.
result The framework yields more accurate committor estimates, reaction rates, and equilibrium constants.
Proposes a method to ensure accurate estimation of rare events in AI systems.
problem Lack of efficiency guarantees in black-box systems for rare-event simulation.
method Integrates deep learning with importance sampling to create a statistically guaranteed estimator.
result Demonstrates effective estimation of rare-event probabilities in AI systems.
In many situations, classes of data points of primary interest also happen to be those that are least numerous. A well-known example is detection of fraudulent transactions among the collection of all financial transactions, the vast majority of which are legitimate. These types of problems fall under the label of `rar…
WEST uses EHRs and expert cases to improve rare disease phenotyping.
problem Limited labeled data for rare diseases.
method Weakly supervised transformer model trained on probabilistic silver-standard labels.
result WEST outperforms existing methods in phenotype classification and subphenotyping.
Rare diseases affect a relatively small number of people, which limits investment in research for treatments and cures. Developing an efficient method for rare disease detection is a crucial first step towards subsequent clinical research. In this paper, we present a semi-supervised learning framework for rare disease …
This research examines rare spurious correlations in neural networks and their impact on accuracy and privacy.
problem Rare spurious correlations in neural networks and their privacy risks.
method Introducing spurious patterns correlated with a fixed class to a few training examples, analyzing ℓ2 regularization and Gaussian noise. result Rare spurious correlations can significantly impact neural network accuracy and privacy, and specific mitigation methods can be effective.
In rare disease physician targeting, a major challenge is how to identify physicians who are treating diagnosed or underdiagnosed rare diseases patients. Rare diseases have extremely low incidence rate. For a specified rare disease, only a small number of patients are affected and a fractional of physicians are involve…
Simulates patient pathways to detect delayed rare disease diagnoses.
problem Delayed rare disease diagnoses in France, causing health system and patient harm.
method Probabilistic modelling of patient pathways to create an alert system.
result Alert system detects and refers wandering patients to CRMRs.
Model predicts travel time under rare conditions using a vector-space model.
problem Predicting travel time under rare temporal conditions (e.g., holidays, school vacations) is challenging due to limited historical data and other temporal changes.
method Presented a vector-space model for encoding rare temporal conditions, allowing coherent representation learning across different conditions.
result Increased performance for travel time prediction over different baselines when using the vector-space encoding for representing the temporal setting.
The detection of rare variants is important for understanding the genetic heterogeneity in mixed samples. Recently, next-generation sequencing (NGS) technologies have enabled the identification of single nucleotide variants (SNVs) in mixed samples with high resolution. Yet, the noise inherent in the biological processe…
Deep CNNs struggle with rare taxa; one-class classifiers help identify them.
problem Efficiently identifying rare benthic macroinvertebrates in insect monitoring.
method Combining deep CNNs with one-class classifiers to identify rare taxa.
result The proposed approach can improve rare species identification, supporting automation.
Detects and mitigates rare subclasses in deep neural networks.
problem Underrepresented classes in training datasets reduce classifier performance.
method Commonality metric for detection, methods for reducing impact during training and exploitation.
result Models compensate for rare subclasses, improving performance and runtime identification.
Study compares resampling methods for rare event prediction in longitudinal studies.
problem Predicting rare events in longitudinal follow-up studies.
method Comparison of resampling methods to improve standard regression models.
result Effect of sampling rate on model predictive performance.
The paper analyzes logistic regression for rare events data, deriving new insights on estimator efficiency and sampling strategies.
problem Binary logistic regression for rare events data with significantly fewer events than controls.
method Derives asymptotic distribution of MLE, proves under-sampling advantage, and compares over-sampling efficiency.
result Under-sampling a small proportion of nonevents can improve efficiency in rare events data analysis.
Proposes Ada-Sit method for mortality prediction of rare diseases.
problem Data insufficiency and clinical diversity of rare diseases make mortality prediction hard.
method Initialization-sharing multi-task learning method (Ada-Sit) for fast adaptation to similar tasks.
result Experimental results show the proposed model is effective for mortality prediction of diverse rare diseases.
PRESTO improves rare event prediction by shrinking towards proportional odds model.
problem Difficult to predict rare events due to class imbalance.
method PRESTO relaxes proportional odds model by estimating separate weights for transitions between categories, imposing L1 penalty to shrink towards proportional odds.
result PRESTO consistently estimates decision boundary weights under sparsity assumption, improving rare probability estimation.
Deep-PrAE improves rare-event simulation for black-box systems.
problem Evaluating rare safety-critical events in learning-based systems.
method Combines deep neural networks with IS to create statistically guaranteed estimations.
result Deep-PrAE provides accurate bounds on safety-critical event probabilities.
Develops a method to simulate rare dangerous events in autonomous systems.
problem Rare dangerous events in safety-critical systems are hard to test in real-world settings.
method Combines exploration, exploitation, and optimization techniques for rare-event simulation.
result Provides rigorous guarantees for the performance of the method.
NOFIS uses normalizing flows to estimate rare event probabilities more efficiently.
problem Accurate estimation of rare event probabilities using conventional methods is inefficient and resource-intensive.
method NOFIS learns a sequence of proposal distributions by minimizing KL divergence losses and estimates rare event probability using importance sampling.
result NOFIS outperforms baseline approaches in estimating rare event probabilities across 10 distinct test cases.