Reduces false positives in lung nodule detection by using unlabeled data.
problem Lack of labeled data for training supervised algorithms in medical imaging.
method Uses pseudo-negative labels from unlabeled data to refine a pulmonary nodule detection network.
result False positive rate reduced from 0.4864 to 0.1266 while maintaining sensitivity.
Computed tomography (CT) generates a stack of cross-sectional images covering a region of the body. The visual assessment of these images for the identification of potential abnormalities is a challenging and time consuming task due to the large amount of information that needs to be processed. In this article we propo…
Convolutional Neural Networks (CNNs) require a large amount of annotated data to learn from, which is often difficult to obtain in the medical domain. In this paper we show that the sample complexity of CNNs can be significantly improved by using 3D roto-translation group convolutions (G-Convs) instead of the more conv…
Machine learning approaches hold great potential for the automated detection of lung nodules in chest radiographs, but training the algorithms requires vary large amounts of manually annotated images, which are difficult to obtain. Weak labels indicating whether a radiograph is likely to contain pulmonary nodules are t…
Motivated by the problem of computer-aided detection (CAD) of pulmonary nodules, we introduce methods to propagate and fuse uncertainty information in a multi-stage Bayesian convolutional neural network (CNN) architecture. The question we seek to answer is "can we take advantage of the model uncertainty provided by one…
System converts 3D lung nodule images into embeddings for retrieval.
problem Retrieving similar 3D lung nodule images for radiologist decision support.
method 3D deep learning, semantic representation, transfer learning, similarity score.
result System can measure similarity between nodule annotations and CBIR results.
Study uses multi-task Bayesian optimization to speed up SVM hyperparameter tuning for nodules diagnosis.
problem Redundant and time-consuming hyperparameter tuning for SVM classifiers in medical imaging.
method Employed multi-task Bayesian optimization to accelerate hyperparameter search.
result Multi-task Bayesian optimization significantly accelerates hyperparameter search.
Reinforcement learning improves self training for medical image segmentation.
problem Lack of labeled data in medical imaging.
method Integrating reinforcement learning into self training for complex segmentation networks.
result Improved segmentation performance with less labeled data.
Lung cancer is the leading cause of cancer-related death worldwide. Early diagnosis of pulmonary nodules in Computed Tomography (CT) chest scans provides an opportunity for designing effective treatment and making financial and care plans. In this paper, we consider the problem of diagnostic classification between beni…
A novel approach for 3D lung nodule segmentation using adaptive ROI and multi-view residual learning.
problem Inaccurate nodule segmentation due to fixed ROI and redundant structures.
method Two-stage approach: 2D ROI patch-wise investigation with adaptive ROI strategy, followed by 2D and 3D VOI investigation with deep residual U-Net.
result Significantly robust and accurate nodule segmentation compared to previous methods.
The state of the art lung nodule detection studies rely on computationally expensive multi-stage frameworks to detect nodules from CT scans. To address this computational challenge and provide better performance, in this paper we propose S4ND, a new deep learning based method for lung nodule detection. Our approach use…
Paper reduces false positives in lung nodule detection using deep learning on point clouds.
problem Reduces false positives in lung nodule detection.
method Uses deep learning models for point clouds to transform 3D CT scan data.
result Achieved 85.98 FROC compared to 77.26 FROC for baseline models.
GD networks improve lung nodule classification accuracy.
problem Difficult classification of lung nodules of varying sizes.
method Proposes Gated-Dilated (GD) networks with Context-Aware sub-network.
result GD network outperforms state-of-the-art models with AUC > 0.95.
Pipeline detects pulmonary embolisms from sparse CT images.
problem Manual diagnosis of pulmonary embolisms is laborious and prone to errors.
method Two-stage pipeline using AI, sparse annotations, and robust models.
result Achieved AUC scores of 0.94 on validation and 0.85 on test sets for severe PEs.
Computer aided diagnostic (CAD) system is crucial for modern med-ical imaging. But almost all CAD systems operate on reconstructed images, which were optimized for radiologists. Computer vision can capture features that is subtle to human observers, so it is desirable to design a CAD system op-erating on the raw data. …
Computed tomography (CT) examinations are commonly used to predict lung nodule malignancy in patients, which are shown to improve noninvasive early diagnosis of lung cancer. It remains challenging for computational approaches to achieve performance comparable to experienced radiologists. Here we present NoduleX, a syst…
U-Det improves lung nodule segmentation in CT images.
problem Challenging shapes and surroundings of lung nodules in CT images.
method End-to-end deep learning with Bi-FPN, Mish activation, and class weights.
result U-Det achieves 82.82% Dice similarity coefficient, comparable to human experts.
3D Axial-Attention improves lung nodule classification accuracy.
problem Limited 3D attention in existing methods.
method Proposes 3D Axial-Attention network with 3D positional encoding.
result 3D Axial-Attention achieves state-of-the-art performance.
Deep Local-Global network improves lung nodule malignancy prediction.
problem Challenging task of classifying lung nodules as benign or malignant.
method Proposes a novel method combining local and global feature extraction.
result Achieved state-of-the-art results with AUC=95.62%.
Generates synthetic lung nodule images for training.
problem Lack of source image data for training machine learning models.
method Autoencoder techniques for 3D shape generation.
result Produces high-quality synthetic 3D images.
Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a fast and robust computer aided system. In this work, we propose an end-to-end tra…
SAPSAM trains CNNs on lung CTs with binary labels, improving CPA detection and localization.
problem Chronic Pulmonary Aspergillosis (CPA) detection and localization on CT scans using binary labels.
method Binary labels, average intensity projections, 2D RGB-like images, hierarchical CNN architectures.
result High classification accuracy, precise localization, predictive power of 2-year survival.
Clearing algorithm improves CT image segmentation accuracy by merging confident annotations.
problem Inaccurate predictions due to noisy annotations from different annotators.
method 3-stage algorithm: scoring annotators, scoring nodules, merging annotations.
result Improves prediction accuracy in CT image segmentation tasks.
Smartphone app diagnoses pulmonary diseases from chest X-rays.
problem Scarcity of training data and class imbalance issues.
method Data Augmentation Generative Adversarial Network (DAGAN) and Convolutional Siamese Network with attention mechanism.
result Achieved 99.30% and 98.40% testing accuracy on Binary/Multiclass scenarios.
GAN normalizes CT scans for consistent radiomic feature values.
problem Variations in dose levels and slice thickness affect radiomic features sensitivity.
method Used a 3D generative adversarial network (GAN) to normalize reduced dose, thick slice images to normal dose, thinner slice images.
result GAN-based approach led to significantly smaller error in radiomic features.
End-to-end CAD system for thyroid nodule classification using multimodal data and expert guidance.
problem Improving accuracy in thyroid nodule classification for clinicians.
method Knowledge-driven DenseNet framework using multimodal ultrasound data and expert cues.
result The proposed system achieves relevant performances in thyroid nodule classification.
Synthetic sampling improves per-class performance in multi-label malignancy prediction.
problem Imbalanced multi-label classification problem in CADx systems.
method Synthetic oversampling techniques using random forest classifier.
result Average 7.22% point increase in sensitivity for minority classes.
This work introduces an integrative approach based on Q-analysis with machine learning. The new approach, called Neural Hypernetwork, has been applied to a case study of pulmonary embolism diagnosis. The objective of the application of neural hyper-network to pulmonary embolism (PE) is to improve diagnose for reducing …
Proposes a novel anomaly detection method for echocardiogram videos.
problem Anomaly detection in echocardiogram videos.
method Dynamic Variational Trajectory Models (TVAE-C, TVAE-R, TVAE-S) trained on healthy infant echocardiogram videos.
result Superior performance in detecting congenital heart defects and pulmonary hypertension.
Modeling disease progression in irregularly observed patients.
problem Irregular patient observation in healthcare databases.
method Continuous-time hidden Markov model with generalized linear model.
result Interpretable model of healthcare utilization events.
The paper uses geometric methods to classify medical data histograms.
problem Classifying medical data histograms for disease diagnosis.
method Information geometry of beta distributions for comparing and classifying histograms.
result Geometric tools, particularly negatively curved Fisher information, enable unique mean calculation and K-means classification.
Method detects airway dilatation with high accuracy.
problem Detecting airway dilatation in lung diseases like IPF.
method Probabilistic model of abrupt relative variations, Bayesian Changepoint Detection.
result Model detects airway dilatation with 2.5mm accuracy.
WEST uses EHRs and expert cases to improve rare disease phenotyping.
problem Limited labeled data for rare diseases.
method Weakly supervised transformer model trained on probabilistic silver-standard labels.
result WEST outperforms existing methods in phenotype classification and subphenotyping.
New method uses probabilistic independence to discover disease signatures from medical records.
problem Insufficiently precise diagnosis of clinical disease leading to treatment failures.
method Unsupervised machine learning using probabilistic independence to disentangle disease patterns.
result Inferred 2000 clinical disease signatures from medical records, improving cancer prediction.
Deep learning ensembles improve COVID-19 detection from chest X-rays.
problem Detecting COVID-19 from chest X-rays using machine learning.
method Custom CNN and ImageNet models, transfer learning, iterative pruning, ensemble learning.
result 99.01% accuracy in detecting COVID-19 from chest X-rays.
UNet++ improves medical image segmentation with deep supervision.
problem Improving accuracy in medical image segmentation.
method Nested U-Net architecture with deep supervision.
result UNet++ achieves significant improvements in IoU scores.
CNNs accurately measure airways and vessels on CT images, improving lung disease diagnosis.
problem Accurately characterizing small pulmonary structures from CT images for disease diagnosis.
method Generative model combined with Convolutional Neural Regressor (CNR) for cross-sectional measurements.
result CNNs provide accurate measurements with physiological correlates.
Improves Bayesian optimization for expensive function evaluations.
problem Optimizing expensive functions with noisy, non-differentiable outputs.
method Proposes a new improvement-based acquisition function.
result Performs at least as well as state-of-the-art acquisition functions, often better.
Chronic obstructive pulmonary disease (COPD) is a lung disease where early detection benefits the survival rate. COPD can be quantified by classifying patches of computed tomography images, and combining patch labels into an overall diagnosis for the image. As labeled patches are often not available, image labels are p…
Anatomical and biophysical modeling of left atrium (LA) and proximal pulmonary veins (PPVs) is important for clinical management of several cardiac diseases. Magnetic resonance imaging (MRI) allows qualitative assessment of LA and PPVs through visualization. However, there is a strong need for an advanced image segment…
New DL algorithm detects critical chest X-ray findings without manual annotations.
problem Lack of explainability and manual annotation costs for DL models in medical imaging.
method Multi-instance learning approach to jointly classify and localize critical findings in CXR.
result Competitive classification results on three CXR datasets.
Generative Adversarial Model improves RV segmentation accuracy in MRI.
problem Accurate segmentation of the right ventricular blood pool from cine MRI sequences.
method Combines FCNN, Gated Recurrent Units (GRU), Generative Adversarial Networks (GAN), and L1 loss function.
result Improves Dice Index and Hausdorff Distance by 0.05 and 3.49 mm respectively.
Proposes a tool to contrast global vs personalized models in clinical prediction.
problem Balancing global vs personalized models in clinical prediction.
method Localized regression approach using autoencoder for dimension reduction.
result Identification of patient subgroups where global models fall short.
Study uses data to analyze COPD patients' impact on hospital systems.
problem Understanding and quantifying resource requirements for COPD patients.
method Combines segmentation, queuing theory, and data recovery techniques.
result Finding useful operational results from incomplete administrative data.
Non-invasive detection of cardiovascular disorders from radiology scans requires quantitative image analysis of the heart and its substructures. There are well-established measurements that radiologists use for diseases assessment such as ejection fraction, volume of four chambers, and myocardium mass. These measuremen…
Improves uncertainty estimates in lung node segmentation.
problem Inaccurate uncertainty estimates in medical segmentation.
method Supervised learning using multi-grader annotation variability.
result Improves predictive uncertainty estimates and sample diversity.
The chest X-ray (CXR) is by far the most commonly performed radiological examination for screening and diagnosis of many cardiac and pulmonary diseases. There is an immense world-wide shortage of physicians capable of providing rapid and accurate interpretation of this study. A radiologist-driven analysis of over two m…
Project aims to diagnose and track IPF disease using deep learning.
problem Diagnosing and tracking IPF disease in lung images.
method Developed a deep learning model for identifying honeycombing and ground glass patterns in HRCT lung images.
result Deep learning model achieved high accuracy in identifying specific lung regions.