Develops a neural surrogate for proton dose calculation using Monte Carlo dropout uncertainty.
arXiv research
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The limits of the nuclear landscape are determined by nuclear binding energies. Beyond the proton drip lines, where the separation energy becomes negative, there is not enough binding energy to prevent protons from escaping the nucleus. Predicting properties of unstable nuclear states in the vast territory of proton em…
Bio-oil molecule assessment is essential for the sustainable development of chemicals and transportation fuels. These oxygenated molecules have adequate carbon, hydrogen, and oxygen atoms that can be used for developing new value-added molecules (chemicals or transportation fuels). One motivation for our study stems fr…
MLPF uses graph neural networks to improve particle-flow reconstruction in high-pileup conditions.
Identifying the flavour of neutral mesons production is one of the most important components needed in the study of time-dependent violation. The harsh environment of the Large Hadron Collider makes it particularly hard to succeed in this task. We present an inclusive flavour-tagging algorithm as an upgrade of…
Recent literature on deep neural networks for tagging of highly energetic jets resulting from top quark decays has focused on image based techniques or multivariate approaches using high-level jet substructure variables. Here, a sequential approach to this task is taken by using an ordered sequence of jet constituents …
Patients suffering from obstructive sleep apnea are mainly treated with continuous positive airway pressure (CPAP). Good compliance with this therapy is broadly accepted as more than 4h of CPAP average use nightly. Although it is a highly effective treatment, compliance with this therapy is problematic to achieve with …
In this paper we present a method for simultaneously segmenting brain tumors and an extensive set of organs-at-risk for radiation therapy planning of glioblastomas. The method combines a contrast-adaptive generative model for whole-brain segmentation with a new spatial regularization model of tumor shape using convolut…
Equivariant neural network simplifies particle physics models.
Tensor networks improve anomaly detection at LHC for new physics.
We apply generative adversarial network (GAN) technology to build an event generator that simulates particle production in electron-proton scattering that is free of theoretical assumptions about underlying particle dynamics. The difficulty of efficiently training a GAN event simulator lies in learning the complicated …
Foundation models trained on collider data improve jet generation tasks.
Centrality, as a geometrical property of the collision, is crucial for the physical interpretation of nucleus-nucleus and proton-nucleus experimental data. However, it cannot be directly accessed in event-by-event data analysis. Common methods for centrality estimation in A-A and p-A collisions usually rely on a single…
Highly accurate potential energy surfaces are of key interest for the detailed understanding and predictive modeling of chemical systems. In recent years, several new types of force fields, which are based on machine learning algorithms and fitted to ab initio reference calculations, have been introduced to meet this r…
Knowledge-based planning (KBP) is an automated approach to radiation therapy treatment planning that involves predicting desirable treatment plans before they are then corrected to deliverable ones. We propose a generative adversarial network (GAN) approach for predicting desirable 3D dose distributions that eschews th…
NSBI approach detects Higgs trilinear coupling with high luminosity upgrade constraints.
Tensor networks improve b-jet classification in high-energy physics.
Machine Learning (ML) is one of the most exciting and dynamic areas of modern research and application. The purpose of this review is to provide an introduction to the core concepts and tools of machine learning in a manner easily understood and intuitive to physicists. The review begins by covering fundamental concept…
Challenge uses unsupervised learning to detect new physics signals at LHC.
Proposes a framework for automated radiation therapy treatment planning with uncertainty quantification.
New disease drug trials use ML to predict best therapy.
Study uses machine learning to optimize antibiotic therapy for MRSA skin infections.
Guidelines for the management of atherosclerotic cardiovascular disease (ASCVD) recommend the use of risk stratification models to identify patients most likely to benefit from cholesterol-lowering and other therapies. These models have differential performance across race and gender groups with inconsistent behavior a…
We develop a prediction-based prescriptive model for learning optimal personalized treatments for patients based on their Electronic Health Records (EHRs). Our approach consists of: (i) predicting future outcomes under each possible therapy using a robustified nonlinear model, and (ii) adopting a randomized prescriptiv…
The chart of the nuclides is limited by particle drip lines beyond which nuclear stability to proton or neutron emission is lost. Predicting the range of particle-bound isotopes poses an appreciable challenge for nuclear theory as it involves extreme extrapolations of nuclear masses beyond the regions where experimenta…
Develops algorithm to find subgroups with different treatment effects in HIV patients.
latrend simplifies longitudinal clustering for numeric measurements.
Determining whether hypotensive patients in intensive care units (ICUs) should receive fluid bolus therapy (FBT) has been an extremely challenging task for intensive care physicians as the corresponding increase in blood pressure has been hard to predict. Our study utilized regression models and attention-based recurre…
Paper uses imitation learning to create efficient insulin policies from MPC demonstrations.
Deep neural network identifies potential SARS-CoV-2 inhibitors.
Spinal cord stimulation has enabled humans with motor complete spinal cord injury (SCI) to independently stand and recover some lost autonomic function. Quantifying the quality of bipedal standing under spinal stimulation is important for spinal rehabilitation therapies and for new strategies that seek to combine spina…
Enforcing safety is a key aspect of many problems pertaining to sequential decision making under uncertainty, which require the decisions made at every step to be both informative of the optimal decision and also safe. For example, we value both efficacy and comfort in medical therapy, and efficiency and safety in robo…
A new graphical model for discrete data without parametric restrictions.
New methods use RL and DA to improve dosing precision and reduce side effects.
Study uses LLMs to create personalized treatment plans for rare gynecological tumors.
Tree-based model averaging improves CATE estimation from diverse sites.
High-dimensional data common in genomics, proteomics, and chemometrics often contains complicated correlation structures. Recently, partial least squares (PLS) and Sparse PLS methods have gained attention in these areas as dimension reduction techniques in the context of supervised data analysis. We introduce a framewo…
New methods for estimating treatment effects with missing data.
Develops methods for finding counterfactual explanations in sequential decision making.
Drug resistance is still a major challenge in cancer therapy. Drug combination is expected to overcome drug resistance. However, the number of possible drug combinations is enormous, and thus it is infeasible to experimentally screen all effective drug combinations considering the limited resources. Therefore, computat…
Modern detectors of cosmic gamma-rays are a special type of imaging telescopes (air Cherenkov telescopes) supplied with cameras with a relatively large number of photomultiplier-based pixels. For example, the camera of the TAIGA-IACT telescope has 560 pixels of hexagonal structure. Images in such cameras can be analyse…
New algorithm speeds up causal inference for large data.
Cardiotoxicity related to cancer therapies has become a serious issue, diminishing cancer treatment outcomes and quality of life. Early detection of cancer patients at risk for cardiotoxicity before cardiotoxic treatments and providing preventive measures are potential solutions to improve cancer patients's quality of …
The paper tracks patient recovery using graphs of joint movement data.
Characterizing a patient's progression through stages of sepsis is critical for enabling risk stratification and adaptive, personalized treatment. However, commonly used sepsis diagnostic criteria fail to account for significant underlying heterogeneity, both between patients as well as over time in a single patient. W…
Feature selection predicts immune state changes in RA mouse model.
In cognitive psychology, automatic and self-reinforcing irrational thought patterns are known as cognitive distortions. Left unchecked, patients exhibiting these types of thoughts can become stuck in negative feedback loops of unhealthy thinking, leading to inaccurate perceptions of reality commonly associated with anx…
This paper presents a proof-of-concept demonstration of triaxial strain tomography from Bragg-edge neutron imaging within a three-dimensional sample. Bragg-edge neutron transmission can provide high-resolution images of the average through thickness strain within a polycrystalline material. This poses an associated ric…