We propose a novel automatic method for accurate segmentation of the prostate in T2-weighted magnetic resonance imaging (MRI). Our method is based on convolutional neural networks (CNNs). Because of the large variability in the shape, size, and appearance of the prostate and the scarcity of annotated training data, we …
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Proposes using MR images to create synthetic CT images for prostate segmentation.
Spatially-aware metrics improve uncertainty evaluation in segmentation.
Deep neural networks have introduced significant advancements in the field of machine learning-based analysis of digital pathology images including prostate tissue images. With the help of transfer learning, classification and segmentation performance of neural network models have been further increased. However, due t…
Deep neural networks predict prostate motion from MR images.
The accurate estimation of predictive uncertainty carries importance in medical scenarios such as lung node segmentation. Unfortunately, most existing works on predictive uncertainty do not return calibrated uncertainty estimates, which could be used in practice. In this work we exploit multi-grader annotation variabil…
The Hausdorff Distance (HD) is widely used in evaluating medical image segmentation methods. However, existing segmentation methods do not attempt to reduce HD directly. In this paper, we present novel loss functions for training convolutional neural network (CNN)-based segmentation methods with the goal of reducing HD…
Enhances uncertainty estimation in medical image segmentation.
Neural networks promise to bring robust, quantitative analysis to medical fields, but adoption is limited by the technicalities of training these networks. To address this translation gap between medical researchers and neural networks in the field of pathology, we have created an intuitive interface which utilizes the…
VarDeepPCA: A Sampling-Free Variational DNN Plugin for OOD Segmentation with Uncertainty Estimation
VarDeepPCA refines medical image segmentation from small datasets, improving anatomical plausibility and reducing errors.
Study compares DL models for medical image segmentation, finds synergistic ensemble strategies improve performance.
Adapts CNN for robust medical image segmentation across different scanners and protocols.
Proposes a new contrastive loss for semi-supervised medical image segmentation.
Study evaluates data augmentation methods for prostate cancer detection in MRI.
Radiological imaging of the prostate is becoming more popular among researchers and clinicians in searching for diseases, primarily cancer. Scans might be acquired with different equipment or at different times for prognosis monitoring, with patient movement between scans, resulting in multiple datasets that need to be…
Histopathology tissue samples are widely available in two states: paraffin-embedded unstained and non-paraffin-embedded stained whole slide RGB images (WSRI). Hematoxylin and eosin stain (H&E) is one of the principal stains in histology but suffers from several shortcomings related to tissue preparation, staining proto…
We describe an adversarial learning approach to constrain convolutional neural network training for image registration, replacing heuristic smoothness measures of displacement fields often used in these tasks. Using minimally-invasive prostate cancer intervention as an example application, we demonstrate the feasibilit…
Proposes a multi-resolution model for prostate cancer classification using mpMRI.
CNN-based prostate cancer grading improves accuracy and efficiency.
A novel deep learning architecture (XmasNet) based on convolutional neural networks was developed for the classification of prostate cancer lesions, using the 3D multiparametric MRI data provided by the PROSTATEx challenge. End-to-end training was performed for XmasNet, with data augmentation done through 3D rotation a…
Study builds tools to detect misinformation in online medical videos.
New method for causal inference in survival outcomes using RDD.
Survival analysis has been developed and applied in the number of areas including manufacturing, finance, economics and healthcare. In healthcare domain, usually clinical data are high-dimensional, sparse and complex and sometimes there exists few amount of time-to-event (labeled) instances. Therefore building an accur…
Develops platforms to analyze social media data for human behavior and emotions.
Optimal cutoff interval for risk scores improves binary classification accuracy.
We propose a Bayesian model that predicts recovery curves based on information available before the disruptive event. A recovery curve of interest is the quantified sexual function of prostate cancer patients after prostatectomy surgery. We illustrate the utility of our model as a pre-treatment medical decision aid, pr…
The paper develops a method to learn cost-optimal sequential testing policies from retrospective data.
Study improves machine learning for estimating survival treatment effects.
We estimate treatment cost-savings from early cancer diagnosis. For breast, lung, prostate and colorectal cancers and melanoma, which account for more than 50% of new incidences projected in 2017, we combine published cancer treatment cost estimates by stage with incidence rates by stage at diagnosis. We extrapolate to…
New method groups genetic data into coherent topics for disease insights.
Segmental structure is a common pattern in many types of sequences such as phrases in human languages. In this paper, we present a probabilistic model for sequences via their segmentations. The probability of a segmented sequence is calculated as the product of the probabilities of all its segments, where each segment …
Bayesian nonparametric method segments multi-sequence time series data.
Segmentation has been a major task in neuroimaging. A large number of automated methods have been developed for segmenting healthy and diseased brain tissues. In recent years, deep learning techniques have attracted a lot of attention as a result of their high accuracy in different segmentation problems. We present a n…
BiPE blends intra-segment and inter-segment encodings for better length extrapolation.
CNNs can be trained with clinically available segmentations for OARs in radiotherapy.
Learning-based methods for visual segmentation have made progress on particular types of segmentation tasks, but are limited by the necessary supervision, the narrow definitions of fixed tasks, and the lack of control during inference for correcting errors. To remedy the rigidity and annotation burden of standard appro…
Develops deep learning for logical code segmentation.
Hybrid CNN improves segmentation and registration of white matter tracts.
Image segmentation is one of the most fundamental tasks of computer vision. In many practical applications, it is essential to properly evaluate the reliability of individual segmentation results. In this study, we propose a novel framework to provide the statistical significance of segmentation results in the form of …
DNA rearrangement processes recombine gene segments that are organized on the chromosome in a variety of ways. The segments can overlap, interleave or one may be a subsegment of another. We use directed graphs to represent segment organizations on a given locus where contigs containing rearranged segments represent ver…
Preformer improves Transformer for long-term time series forecasting.
We introduce a novel Deep Learning framework, which quantitatively estimates image segmentation quality without the need for human inspection or labeling. We refer to this method as a Quality Assurance Network -- QANet. Specifically, given an image and a `proposed' corresponding segmentation, obtained by any method inc…
Study uses LLM to extract and compare segment disclosures from financial filings.
LSTM-based speaker verification usually uses a fixed-length local segment randomly truncated from an utterance to learn the utterance-level speaker embedding, while using the average embedding of all segments of a test utterance to verify the speaker, which results in a critical mismatch between testing and training. T…
Deep learning improves automatic image segmentation.
This paper reviews deep learning for multi-modality medical image segmentation.
Accurate and robust cell nuclei classification is the cornerstone for a wider range of tasks in digital and Computational Pathology. However, most machine learning systems require extensive labeling from expert pathologists for each individual problem at hand, with no or limited abilities for knowledge transfer between…