ODTLearn learns optimal decision trees for predictive and prescriptive tasks.
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A new neural network model for optimal treatment assignment.
Method learns optimal treatment policies from observational data.
PNNs improve treatment outcomes in TAVR and liver trauma.
PNNs improve personalized healthcare policies using mixed integer programming.
A model learns symptom-drug relations for PD patients.
The Prescriptive Canvas improves business outcomes by directly prescribing actions based on predictions.
Paper integrates predictive and prescriptive tasks using bilevel optimization.
We address the problem of prescribing an optimal decision in a framework where the cost function depends on uncertain problem parameters that need to be learned from data. Earlier work proposed prescriptive formulations based on supervised machine learning methods. These prescriptive methods can factor in contextual in…
The opioid epidemic in the United States claims over 40,000 lives per year, and it is estimated that well over two million Americans have an opioid use disorder. Over-prescription and misuse of prescription opioids play an important role in the epidemic. Individuals who are prescribed opioids, and who are diagnosed wit…
Deep learning predicts drug prescriptions across global health records.
Local classification of surfaces and hypersurfaces with radial mean curvature.
Paper solves curvature prescription problem on surfaces with boundary.
This paper addresses a novel data science problem, prescriptive price optimization, which derives the optimal price strategy to maximize future profit/revenue on the basis of massive predictive formulas produced by machine learning. The prescriptive price optimization first builds sales forecast formulas of multiple pr…
P.Lecomte has proposed to take into account the covariant derivatives used to build ordering prescriptions for the naturality of transformation properties and has conjectured that there exists an natural ordering prescription for differential operators of any orders between density bundles which in addition is invarian…
The study compares Euclidean and cosine distances in medical drug prescription prediction.
New approach for estimating individual treatment effects in low compliance settings.
Prescribing, by conformal transformation, the kth-elementary symmetric polynomial of the Schouten tensor to be constant is a generalisation of the Yamabe problem. On compact Riemannian n-manifolds we show that, for k between and including 3 and n, this prescription equation is an Euler-Lagrange equation of some act…
Study proves curvature prescription on spheres for k ≥ n/2.
In this paper, we introduce a framework for solving finite-horizon multistage optimization problems under uncertainty in the presence of auxiliary data. We assume the joint distribution of the uncertain quantities is unknown, but noisy observations, along with observations of auxiliary covariates, are available. We uti…
In this paper we give a new proof of a theorem by Alexandrov on the Gauss curvature prescription of Euclidean convex sets. This proof is based on the duality theory of convex sets and on optimal mass transport. A noteworthy property of this proof is that it does not rely neither on the theory of convex polyhedra nor on…
Arborescent knots are the ones which can be represented in terms of double fat graphs or equivalently as tree Feynman diagrams. This is the class of knots for which the present knowledge is enough for lifting topological description to the level of effective analytical formulas. The paper describes the origin and struc…
Two problems concerning asymptotically hyperbolic manifolds with an inner boundary are studied. First, we study scalar curvature presciption with either Dirichlet or mean curvature prescription interior boundary condition. Then we apply those results to the Lichnerowicz equation with (future or past) apparent horizon i…
Simplifies complex pricing models for better interpretability and revenue.
In this paper, we study conformal invariants that arise from nodal sets and negative eigenvalues of conformally covariant operators; more specifically, the GJMS operators, which include the Yamabe and Paneitz operators. We give several applications to curvature prescription problems. We establish a version in conformal…
End-to-end pipeline for data-driven decision making in mixed-integer optimization.
For any compact manifold of dimension n>=5, we prescribe the volume and any finite part of the spectrum of the Hodge Laplacian acting on diffential forms of degree 1<p<n-1 (exept for p=n/2 if n is even), within a given conformal class. When n<5 and when p=0,1,n-1,n, and p=n/2 if n is even, this simultaneous prescriptio…
We prove that, for a generic set of smooth prescription functions on a closed ambient manifold, there always exists a nontrivial, smooth, closed hypersurface of prescribed mean curvature . The solution is either an embedded minimal hypersurface with integer multiplicity, or a non-minimal almost embedded hypersur…
Dynamic treatment recommendation systems based on large-scale electronic health records (EHRs) become a key to successfully improve practical clinical outcomes. Prior relevant studies recommend treatments either use supervised learning (e.g. matching the indicator signal which denotes doctor prescriptions), or reinforc…
We prove existence of compact spacelike hypersurfaces with prescribed k - curvature in de Sitter space, where the prescription function depends on both space and the tilt function.
Solves curvature prescription on rotational surfaces.
We extend our studies of a quantum field model defined on a lattice having the dilation group as a local gauge symmetry. The model is relevant in the cross-disciplinary area of econophysics. A corresponding proposal by Ilinski aimed at gauge modeling in non-equilibrium pricing is realized as a numerical simulation of t…
Let be an open Riemann surface and be an integer. We prove that on any closed discrete subset of one can prescribe the values of a conformal minimal immersion . Our result also ensures jet-interpolation of given finite order, and hence, in particular, one may in addition prescribe the…
In this paper it is hown that given any smooth, positive function f on a closed, smooth manifold of dimension greater than four and with positive Paneitz invariant, there exists a metric on M such that = f.
The paper solves curvature prescription on a disk with negative Gaussian curvature.
Study uses holography to analyze entanglement entropy in deformed CFTs.
New approach makes deep reinforcement learning robust without assuming adversary knowledge.
In this note we establish the large time non-negativity of the heat kernel for a class of elliptic differential operators on closed, Riemannian manifolds, and apply this result to a problem from conformal differential geometry.
On any compact manifold of dimension greater than 6, we prescribe the volume and any finite part of the spectrum Hodge Laplacian acting on -form for . In particular, we prescribe the multiplicity of the first eigenvalues.
We develop a prediction-based prescriptive model for learning optimal personalized treatments for patients based on their Electronic Health Records (EHRs). Our approach consists of: (i) predicting future outcomes under each possible therapy using a robustified nonlinear model, and (ii) adopting a randomized prescriptiv…
We outline Hutchings's prescription that produces an ECH analog of Latschev and Wendl's algebraic -torsion in the context of , a variant of ECH used in a proof of the isomorphism between Heegaard Floer and Seiberg-Witten Floer homologies; and we explain how it translates into Heegaard Floer homology.
Laboratory testing and medication prescription are two of the most important routines in daily clinical practice. Developing an artificial intelligence system that can automatically make lab test imputations and medication recommendations can save costs on potentially redundant lab tests and inform physicians of a more…
We augment linear Support Vector Machine (SVM) classifiers by adding three important features: (i) we introduce a regularization constraint to induce a sparse classifier; (ii) we devise a method that partitions the positive class into clusters and selects a sparse SVM classifier for each cluster; and (iii) we develop a…
Study compares two methods to extend invariants, finding incompatibility for Brieskorn spheres.
As a new step in the study of rectangularly-colored knot polynomials, we reformulate the prescription of arXiv:1606.06015 for twist knots in the double-column representations in terms of skew Schur polynomials. These, however, are mysteriously shifted from the standard topological locus, what makes further gen…
In this paper, we combine ideas from machine learning (ML) and operations research and management science (OR/MS) in developing a framework, along with specific methods, for using data to prescribe optimal decisions in OR/MS problems. In a departure from other work on data-driven optimization and reflecting our practic…
For any Lie groupoid , the vector bundle dual to the associated Lie algebroid is canonically a Poisson manifold. The (reduced) C*-algebra of (as defined by A. Connes) is shown to be a strict quantization (in the sense of M. Rieffel) of . This is proved using a generalization of Weyl's quantization…
Paper proposes a method to quantify and explain machine learning uncertainty in predictive process monitoring.