PULSE learns representations from physiological time series.
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We developed a new approach for the analysis of physiological time series. An iterative convolution filter is used to decompose the time series into various components. Statistics of these components are extracted as features to characterize the mechanisms underlying the time series. Motivated by the studies that show …
Late fusion of clinical notes and physiological data improves ICU mortality prediction.
PerCDL learns personalized dictionaries for physiological signals combining global and local structures.
DecompKAN improves time series forecasting accuracy and transparency.
Paper uses topological data analysis for time series classification.
PHASE predicts surgical complications from physiological signals.
Here we propose a method, based on detrended covariance which we call detrended cross-correlation analysis (DXA), to investigate power-law cross-correlations between different simultaneously-recorded time series in the presence of non-stationarity. We illustrate the method by selected examples from physics, physiology,…
Multi-output Gaussian processes (GPs) are a flexible Bayesian nonparametric framework that has proven useful in jointly modeling the physiological states of patients in medical time series data. However, capturing the short-term effects of drugs and therapeutic interventions on patient physiological state remains chall…
Monitoring physiological responses to hemodynamic stress can help in determining appropriate treatment and ensuring good patient outcomes. Physicians' intuition suggests that the human body has a number of physiological response patterns to hemorrhage which escalate as blood loss continues, however the exact etiology a…
Neural networks are becoming more and more popular for the analysis of physiological time-series. The most successful deep learning systems in this domain combine convolutional and recurrent layers to extract useful features to model temporal relations. Unfortunately, these recurrent models are difficult to tune and op…
Time series models such as dynamical systems are frequently fitted to a cohort of data, ignoring variation between individual entities such as patients. In this paper we show how these models can be personalised to an individual level while retaining statistical power, via use of multi-task learning (MTL). To our knowl…
This paper proposes a nonparametric Bayesian method for exploratory data analysis and feature construction in continuous time series. Our method focuses on understanding shared features in a set of time series that exhibit significant individual variability. Our method builds on the framework of latent Diricihlet alloc…
In this paper, we present a new deep learning architecture for addressing the problem of supervised learning with sparse and irregularly sampled multivariate time series. The architecture is based on the use of a semi-parametric interpolation network followed by the application of a prediction network. The interpolatio…
We generalize a support vector machine to a support spinor machine by using the mathematical structure of wedge product over vector machine in order to extend field from vector field to spinor field. The separated hyperplane is extended to Kolmogorov space in time series data which allow us to extend a structure of sup…
Automatic prediction of emotion promises to revolutionise human-computer interaction. Recent trends involve fusion of multiple data modalities - audio, visual, and physiological - to classify emotional state. However, in practice, collection of physiological data `in the wild' is currently limited to heartbeat time ser…
SigTime learns interpretable signatures from time series data.
Study builds models to predict post-cardiac arrest outcomes using patient data.
Automatic detection of emotion has the potential to revolutionize mental health and wellbeing. Recent work has been successful in predicting affect from unimodal electrocardiogram (ECG) data. However, to be immediately relevant for real-world applications, physiology-based emotion detection must make use of ubiquitous …
Fluctuations in heart rate are intimately tied to changes in the physiological state of the organism. We examine and exploit this relationship by classifying a human subject's wake/sleep status using his instantaneous heart rate (IHR) series. We use a convolutional neural network (CNN) to build features from the IHR se…
TQA improves prediction intervals for time series data by adjusting quantiles for both cross-sectional and longitudinal coverage.
The supervised learning paradigm is limited by the cost - and sometimes the impracticality - of data collection and labeling in multiple domains. Self-supervised learning, a paradigm which exploits the structure of unlabeled data to create learning problems that can be solved with standard supervised approaches, has sh…
Timely prediction of clinically critical events in Intensive Care Unit (ICU) is important for improving care and survival rate. Most of the existing approaches are based on the application of various classification methods on explicitly extracted statistical features from vital signals. In this work, we propose to elim…
While the volume of electronic health records (EHR) data continues to grow, it remains rare for hospital systems to capture dense physiological data streams, even in the data-rich intensive care unit setting. Instead, typical EHR records consist of sparse and irregularly observed multivariate time series, which are wel…
New method detects change points in quasi-periodic signals without supervision.
Objective: Predict individual septic children's personalized physiologic responses to vasoactive titrations by training a Recurrent Neural Network (RNN) using EMR data. Materials and Methods: This study retrospectively analyzed EMR of patients admitted to a pediatric ICU from 2009 to 2017. Data included charted time se…
We study the dynamics of correlation and variance in systems under the load of environmental factors. A universal effect in ensembles of similar systems under the load of similar factors is described: in crisis, typically, even before obvious symptoms of crisis appear, correlation increases, and, at the same time, vari…
Bayesian model detects internal bleeding in ICU patients.
Modeling physiological time-series in ICU is of high clinical importance. However, data collected within ICU are irregular in time and often contain missing measurements. Since absence of a measure would signify its lack of importance, the missingness is indeed informative and might reflect the decision making by the c…
Sepsis is a poorly understood and potentially life-threatening complication that can occur as a result of infection. Early detection and treatment improves patient outcomes, and as such it poses an important challenge in medicine. In this work, we develop a flexible classifier that leverages streaming lab results, vita…
New model predicts blood glucose in diabetics with improved accuracy.
This study benchmarks changepoint detection algorithms on cardiac time series data.
Neural recordings are nonstationary time series, i.e. their properties typically change over time. Identifying specific changes, e.g. those induced by a learning task, can shed light on the underlying neural processes. However, such changes of interest are often masked by strong unrelated changes, which can be of physi…
We present a scalable end-to-end classifier that uses streaming physiological and medication data to accurately predict the onset of sepsis, a life-threatening complication from infections that has high mortality and morbidity. Our proposed framework models the multivariate trajectories of continuous-valued physiologic…
We study quantitatively the level of false multifractal signal one may encounter while analyzing multifractal phenomena in time series within multifractal detrended fluctuation analysis (MF-DFA). The investigated effect appears as a result of finite length of used data series and is additionally amplified by the long-t…
PSEUDo learns patterns in multivariate time series with locality-sensitive hashing and relevance feedback.
Acute kidney injury (AKI) is a common and serious complication after a surgery which is associated with morbidity and mortality. The majority of existing perioperative AKI risk score prediction models are limited in their generalizability and do not fully utilize the physiological intraoperative time-series data. Thus,…
Neurons predict future scalar inputs by learning top modes of lag vectors.
Deep network clusters hospital patients' vital signs.
In this paper, we present an experimental study for the classification of perceived human stress using non-invasive physiological signals. These include electroencephalography (EEG), galvanic skin response (GSR), and photoplethysmography (PPG). We conducted experiments consisting of steps including data acquisition, fe…
This paper investigates the use of distributed processing on the problem of emotion recognition from physiological sensors using a popular machine learning library on distributed mode. Specifically, we run a random forests classifier on the biosignal-data, which have been pre-processed to form exclusive groups in an un…
Personalized stress model using transfer learning from 20 participants.
Deep learning models predict postoperative complications more accurately than random forests.
Falls prevention, especially in older people, becomes an increasingly important topic in the times of aging societies. In this work, we present Gated Recurrent Unit-based neural networks models designed for predicting falls (syncope). The cardiovascular systems signals used in the study come from Gravitational Physiolo…
Model improves emotion recognition using multiple physiological signals.
Computational Drug Repositioning (CDR) is the task of discovering potential new indications for existing drugs by mining large-scale heterogeneous drug-related data sources. Leveraging the patient-level temporal ordering information between numeric physiological measurements and various drug prescriptions provided in E…
New framework for forecasting psychological processes from ILD.
We propose a modified time lag random matrix theory in order to study time lag cross-correlations in multiple time series. We apply the method to 48 world indices, one for each of 48 different countries. We find long-range power-law cross-correlations in the absolute values of returns that quantify risk, and find that …