Improved forecasting of suicide attempts using LSGPs for patients with little data.
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Efficiently fine-tunes patient-independent seizure detection models with tensor kernel machine.
Personalized models explain TB treatment outcomes considering patient context.
Simulates patient pathways to detect delayed rare disease diagnoses.
Currently, approximately 30% of epileptic patients treated with antiepileptic drugs (AEDs) remain resistant to treatment (known as refractory patients). This project seeks to understand the underlying similarities in refractory patients vs. other epileptic patients, identify features contributing to drug resistance acr…
Cluster analysis aims at separating patients into phenotypically heterogenous groups and defining therapeutically homogeneous patient subclasses. It is an important approach in data-driven disease classification and subtyping. Acute coronary syndrome (ACS) is a syndrome due to sudden decrease of coronary artery blood f…
The health outcomes of high-need patients can be substantially influenced by the degree of patient engagement in their own care. The role of care managers includes that of enrolling patients into care programs and keeping them sufficiently engaged in the program, so that patients can attain various goals. The attainmen…
Characterizing a patient's progression through stages of sepsis is critical for enabling risk stratification and adaptive, personalized treatment. However, commonly used sepsis diagnostic criteria fail to account for significant underlying heterogeneity, both between patients as well as over time in a single patient. W…
Longitudinal patient data has the potential to improve clinical risk stratification models for disease. However, chronic diseases that progress slowly over time are often heterogeneous in their clinical presentation. Patients may progress through disease stages at varying rates. This leads to pathophysiological misalig…
Model predicts wound and episode-level readmission risk and time to re-admit.
We develop a personalized real time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs. Heterogeneity of the patients population is captured via a hierarchical latent class model. The proposed algorithm aims t…
To address potential gaps noted in patient monitoring in the hospital, a novel patient behavior detection system using mmWave radar and deep convolution neural network (CNN), which supports the simultaneous recognition of multiple patients' behaviors in real-time, is proposed. In this study, we use an mmWave radar to t…
Study automates detection of visitation disruptions in ICU patients.
Study develops electronic phenotypes of ICU patient acuity.
Machine learning detects NASH patients from medical claims data.
The paper tracks patient recovery using graphs of joint movement data.
Multi-output Gaussian processes (GPs) are a flexible Bayesian nonparametric framework that has proven useful in jointly modeling the physiological states of patients in medical time series data. However, capturing the short-term effects of drugs and therapeutic interventions on patient physiological state remains chall…
Deep learning model creates patient representations for scalable EHR-based stratification.
Enhances understanding of patient healthcare journeys using self-attention.
Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative effectiveness research. One major carrier for conducting patient similarity resea…
Deep learning clusters patient time-series data for better prognosis.
Many computational models were proposed to extract temporal patterns from clinical time series for each patient and among patient group for predictive healthcare. However, the common relations among patients (e.g., share the same doctor) were rarely considered. In this paper, we represent patients and clinicians relati…
Paper proposes a new method for more accurate group testing of infected patients.
Language models improve clinical prediction models using EHR data.
Rare diseases affecting 350 million individuals are commonly associated with delay in diagnosis or misdiagnosis. To improve those patients' outcome, rare disease detection is an important task for identifying patients with rare conditions based on longitudinal medical claims. In this paper, we present a deep learning m…
Over the past decades, both critical care and cancer care have improved substantially. Due to increased cancer-specific survival, we hypothesized that both the number of cancer patients admitted to the ICU and overall survival have increased since the millennium change. MIMIC-III, a freely accessible critical care data…
Bayesian methods improve group testing for identifying infected patients.
Tens of millions of women suffer from infertility worldwide each year. In vitro fertilization (IVF) is the best choice for many such patients. However, IVF is expensive, time-consuming, and both physically and emotionally demanding. The first question that a patient usually asks before the IVF is how likely she will co…
VBphenoR uses variational Bayes for EHR-based patient phenotyping.
Enhances causal estimation using unlabeled offline ICU data.
Deep learning model predicts severe COVID-19 outcomes.
Improving the quality of end-of-life care for hospitalized patients is a priority for healthcare organizations. Studies have shown that physicians tend to over-estimate prognoses, which in combination with treatment inertia results in a mismatch between patients wishes and actual care at the end of life. We describe a …
Method infers TCR effects on disease using patient data.
The introduction of data analytics into medicine has changed the nature of patient treatment. In this, patients are asked to disclose personal information such as genetic markers, lifestyle habits, and clinical history. This data is then used by statistical models to predict personalized treatments. However, due to pri…
Model identifies key problems in HIV patients' records.
Study predicts risk of true-lumen narrowing after ATAAD surgery using CT data.
Alzheimer's disease (AD) is the most common neurodegenerative disease in older people. Despite considerable efforts to find a cure for AD, there is a 99.6% failure rate of clinical trials for AD drugs, likely because AD patients cannot easily be identified at early stages. This project investigated machine learning app…
Proposes a framework for personalized treatment recommendations using observational data.
We develop a neural network model to classify liver cancer patients into high-risk and low-risk groups using genomic data. Our approach provides a novel technique to classify big data sets using neural network models. We preprocess the data before training the neural network models. We first expand the data using wavel…
Adaptive prediction timing improves healthcare outcomes by predicting patient events at the right frequency.
Patient journeys are compared to find clusters of similar disease trajectories.
Identifies patient-specific root causes of disease using structural equation models.
We partner with a leading European healthcare provider and design a mechanism to match patients with family doctors in primary care. We define the matchmaking process for several distinct use cases given different levels of available information about patients. Then, we adopt a hybrid recommender system to present each…
In the scenario of real-time monitoring of hospital patients, high-quality inference of patients' health status using all information available from clinical covariates and lab tests is essential to enable successful medical interventions and improve patient outcomes. Developing a computational framework that can learn…
Machine learning predicts trauma patient mortality risk.
Generative models create personalized patient health simulations.
In this paper, we introduce the use of a personalized Gaussian Process model (pGP) to predict the key metrics of Alzheimer's Disease progression (MMSE, ADAS-Cog13, CDRSB and CS) based on each patient's previous visits. We start by learning a population-level model using multi-modal data from previously seen patients us…
This study addresses the issue of predicting the glaucomatous visual field loss from patient disease datasets. Our goal is to accurately predict the progress of the disease in individual patients. As very few measurements are available for each patient, it is difficult to produce good predictors for individuals. A rece…