A model learns symptom-drug relations for PD patients.
problem Automatic prescription recommendation for Parkinson's Disease patients.
method Builds a dataset of PD symptoms and prescriptions, learns latent symptom space, uses alternating optimization.
result Effective in recommending suitable prescription drugs for new PD patients.
MRI identifies chronic symptoms in mTBI patients.
problem Chronic symptoms in mTBI patients are hard to characterize.
method Multi-parametric MRI and low-dimensional projection.
result MRI metrics correlate with patient symptoms.
Bayesian networks and ML improve COVID-19 symptom classification and severity analysis.
problem Understanding the relationship between COVID-19 symptoms and demographic variables.
method Bayesian network structure learning followed by unsupervised clustering and demographic symptom identification.
result 99.99% testing accuracy compared to 41.15% for a heuristic method.
This paper studies the trade-off between model accuracy and coverage for diagnosis models used by patients.
problem Balancing accuracy and coverage in diagnosis models for patient use.
method Learned diagnosis models with varying coverage from EHR data.
result A 1% drop in top-3 accuracy for every 10 diseases added to the coverage.
Research uses activity analysis to identify mental health symptoms.
problem Identifying mental health symptoms using objective activity metrics.
method Proposes a framework for mHealth monitoring of psychiatric patients based on physical activity time series.
result Identifies distinct behavioural phenotypes and measures for mood assessment.
This paper presents an example of how demographical characteristics of patients influence their susceptibility to certain medical conditions. In this paper, we investigate the association of health conditions to age of patients in a heterogeneous population. We show that besides the symptoms a patients is having, the a…
Deep learning system tracks stool consistency for GI disease assessment.
problem Lack of objective stool consistency measurements in chronic GI disease.
method Computer vision and deep convolutional neural networks (CNN).
result Developed a stool detection and tracking system.
We present an operational component of a real-world patient triage system. Given a specific patient presentation, the system is able to assess the level of medical urgency and issue the most appropriate recommendation in terms of best point of care and time to treat. We use an attention-based convolutional neural netwo…
There is tremendous interest in precision medicine as a means to improve patient outcomes by tailoring treatment to individual characteristics. An individualized treatment rule formalizes precision medicine as a map from patient information to a recommended treatment. A treatment rule is defined to be optimal if it max…
Online learning improves dengue fever detection with minimal training data.
problem Improving dengue fever detection accuracy with limited training data.
method Online learning approach for incremental learning from patient symptoms and diagnostic investigations.
result The proposed model effectively identifies patients with high likelihood of dengue disease.
Study discovers rules linking patient symptoms to unplanned ICU transfers.
problem Identifying patients at risk for unplanned ICU transfers.
method Mixed-integer optimization approach to learn association rules.
result Significant rules discovered for each patient subgroup.
System recommends disease treatments based on big data and cloud computing.
problem Inaccurate disease classification and treatment recommendations due to complex symptoms and multi-pathogenesis.
method DPCA for disease-symptom clustering, Apriori for D-D and D-T rules, parallel Apache Spark implementation.
result Effective disease-symptom clustering and accurate treatment recommendations for inexperienced doctors.
AI model identifies chemical agents in MCI with high accuracy.
problem Identifying chemical agents in mass casualty incidents.
method Reverse engineered signs/symptoms, trained using ANN, BDT, and WISER.
result WISER outperformed ANN and BDT in identifying chemical agents.
CNN learns diabetic syndromes from patient records.
problem Syndrome differentiation in TCM is complex and lacks standardization.
method Multi-instance multi-task learning with CNN.
result Outperforms other methods on diabetes dataset.
Model predicts HU response for sickle cell patients.
problem Predicting which sickle cell patients will respond to Hydroxyurea.
method Developed Deep Artificial Neural Network models.
result 92.6% accuracy in predicting HbF response.
The behaviors of patients with depression are usually difficult to predict because the patients demonstrate the symptoms of a depressive episode without a warning at unexpected times. The goal of this research is to build algorithms that detect signals of such unusual moments so that doctors can be proactive in approac…
Proposes TPIS for early and low-cost TB vs. pneumonia diagnosis.
problem Challenges in differentiating TB from pneumonia.
method Two-step decision support system with stacked ensemble classifiers.
result TPIS outperforms other methods in early and final diagnosis.
Develops a two-stage conformal prediction method for Parkinson's disease medication needs.
problem Heterogeneous disease progression and treatment response in Parkinson's Disease.
method Two-stage conformal prediction framework with statistical guarantees.
result Quantifies uncertainty in medication needs predictions, improving clinical trust and quality of life.
Study uses logistic regression and association rules to identify early symptoms of malignant mesothelioma.
problem Difficult diagnosis of malignant mesothelioma leading to late-stage detection and poor patient survival.
method Implemented logistic regression and developed association rules to identify early symptoms.
result Categorical logistic regression improved training accuracy from 72.30% to 81.40%.
Counterfactual diagnosis improves medical accuracy and safety.
problem Existing diagnostic algorithms struggle with distinguishing correlation from causation.
method Reformulated diagnosis as a counterfactual inference task and derived new counterfactual diagnostic algorithms.
result Counterfactual diagnostic algorithms significantly improve accuracy and safety compared to standard Bayesian algorithms.
Deep learning model creates patient representations for scalable EHR-based stratification.
problem Challenges in summarizing and representing patient data from EHRs prevent scalable stratification analysis.
method Unsupervised framework based on deep learning (ConvAE) using word embeddings, CNNs, and autoencoders.
result ConvAE significantly outperformed baselines in clustering diverse patient cohorts, identifying clinically relevant subtypes.
Framework integrates mental disorder measurements for personalized treatment.
problem Optimizing treatment for mental disorders with latent mental states and heterogeneity.
method Measurement theory and multi-layer neural network for complex treatment effects.
result Learned treatment policies outperform alternatives on heterogeneous treatment effects.
Machine learning model diagnoses COVID-19 from routine blood tests.
problem Difficulty in diagnosing COVID-19 due to inconsistent blood parameter changes.
method Constructed a machine learning model using 5,333 patients with various infections and 160 COVID-19-positive patients.
result Cross-validated AUC of 0.97, sensitivity of 81.9%, specificity of 97.9%.
Study predicts internet-based treatment effects for GPPPD based on dyadic coping.
problem Identifying which patients will benefit most from internet-based GPPPD treatment.
method Developed a multivariable decision tree model using recursive partitioning.
result Predicts large effects for high dyadic coping patients, small effects for low dyadic coping patients.
In this work, we consider the problem of predicting the course of a progressive disease, such as cancer or Alzheimer's. Progressive diseases often start with mild symptoms that might precede a diagnosis, and each patient follows their own trajectory. Patient trajectories exhibit wild variability, which can be associate…
Machine learning aids in diagnosing Parkinson's disease with higher accuracy.
problem Subjectivity in traditional PD diagnosis methods and missed early symptoms.
method Machine learning applied to various data modalities for PD and control group classification.
result Machine learning methods show high potential for improving PD diagnosis.
This study evaluates a health knowledge graph for robustness in EHRs.
problem Evaluate robustness of a health knowledge graph in EHRs.
method Analyze sample size, unmeasured confounders, and non-linear functions.
result Identify sample size and unmeasured confounders as major sources of error.
Framework extracts symptoms from EHRs for rapid disease outbreak detection.
problem Extracting relevant data from unstructured medical texts.
method Conformal active learning for efficient data mining.
result Framework achieves strong performance with minimal manual labeling.
Study predicts hearing recovery in MD patients using TEOAE signals.
problem Predicting hearing recovery in MD patients during acute episodes.
method Applied machine learning to TEOAE signals from MD patients, using SVM for classification.
result Baseline TEOAE parameters can predict hearing recovery in MD patients.
Study integrates causal inference and temporal complexity measures to analyze mental health symptoms.
problem Examining how individual symptom trajectories reveal diagnostic patterns in mental disorders.
method Causal inference, graph analysis, temporal complexity measures, machine learning.
result 91% accuracy in diagnosing symptom dynamics, highlighting disorder-specific causal mechanisms.
This study improves early prediction of CPAP therapy compliance.
problem Predicting early compliance with CPAP therapy to improve patient outcomes.
method Built classifiers for compliance at three CPAP therapy follow-up points.
result Month 3 classifier achieved highest f1-score of 87% in cross-validation and test.
Acute respiratory infections have epidemic and pandemic potential and thus are being studied worldwide, albeit in many different contexts and study formats. Predicting infection from symptom data is critical, though using symptom data from varied studies in aggregate is challenging because the data is collected in diff…
BIN and CBN models infer health variables from symptoms and signals.
problem Inferring health variables from symptoms and signals.
method Bidirectional inference networks (BIN) and composite BIN (CBIN).
result CBIN achieves state-of-the-art performance and better accuracy.
Bluetooth data predicts depression severity, showing 18.8% extra variance.
problem Predicting depressive symptom severity using Bluetooth data.
method Extracted 49 Bluetooth features from NBDC data, used linear mixed-effect and hierarchical Bayesian linear regression models.
result Hierarchical Bayesian model achieved best prediction metrics (R2=0.526, RMSE=3.891).
The availability of a large amount of electronic health records (EHR) provides huge opportunities to improve health care service by mining these data. One important application is clinical endpoint prediction, which aims to predict whether a disease, a symptom or an abnormal lab test will happen in the future according…
A new framework estimates causal effects for ordinal variables.
problem Existing causal inference methods fail for ordinal data.
method Presumes a latent Gaussian DAG model with constrained covariance matrix.
result Closed-form function for ordinal causal effects in latent space.
In tropical regions, populations continue to suffer morbidity and mortality from malaria and arboviral diseases. In Kedougou (Senegal), these illnesses are all endemic due to the climate and its geographical position. The co-circulation of malaria parasites and arboviruses can explain the observation of coinfected case…
Study develops a dynamic risk model for COVID-19 mortality using UK Biobank data.
problem Developing tools to monitor high-risk patients during the COVID-19 pandemic.
method Data-driven random forest classification model using baseline characteristics and symptoms.
result Model predicts COVID-19 mortality with excellent performance (AUC: 0.91), identifying novel predictors.
Paper presents estimators for entropy and information in probabilistic models.
problem Estimating entropy and mutual information in high dimensions is challenging.
method EEVI uses importance sampling with proposal distributions like amortized variational inference and sequential Monte Carlo.
result EEVI delivers accurate upper and lower bounds on information quantities.
This study evaluates handwriting features to diagnose Parkinson's disease.
problem Diagnosing Parkinson's disease through handwriting analysis.
method Kinematic, geometrical, and non-linear features were evaluated using K-nearest neighbors, support vector machines, and random forest classifiers.
result Up to 93.1% accuracy in classifying Parkinson's disease and healthy subjects.
This paper tackles efficient testing strategies for COVID-19 by using a partially observable MDP approach.
problem Greedy testing strategies miss dormant virus areas, leading to inefficient use of testing resources.
method Develops efficient learning strategies based on policy iteration and look-ahead rules for a sequential learning-based resource allocation problem.
result Shows that the testing problem can be effectively managed using a partially observable MDP approach.
We have recently seen many successful applications of recurrent neural networks (RNNs) on electronic medical records (EMRs), which contain histories of patients' diagnoses, medications, and other various events, in order to predict the current and future states of patients. Despite the strong performance of RNNs, it is…
Paper characterizes early-stage dementia signatures from sensor data.
problem Detecting early-stage dementia from sensor data.
method Developed bespoke behavioural models from longitudinal sensor data.
result Found subtle differences in sleep quality and wandering between dementia patients and controls.
Proposes a new approach to improve disease prediction by considering who generates the data.
problem Improving disease prediction across different datasets considering who generates the data.
method Formulates domain adaptation as a multi-source hierarchical Bayesian framework.
result Improves prediction accuracy in target datasets with largely unlabelled data.
Analyzes COVID-19 data to predict mortality, forecast spread, and optimize resource allocation.
problem Challenges in patient triage, treatment, and care management during the pandemic.
method Integrated four-step approach combining descriptive, predictive, and prescriptive analytics.
result Optimized resource allocation and informed policy decisions.
Low-cost device diagnoses diseases using deep learning.
problem Limited healthcare access and variable disease properties.
method Deep Neural Networks (DNNs) and Convolutional Neural Networks (CNNs) on a Raspberry Pi Zero.
result Achieves 90% accuracy for symptom-based diagnoses and 91% for visual skin diseases.
Deep learning diagnoses MS from smartphone data.
problem Diagnosing MS with complex clinical assessments and tests.
method Deep-learning approach using smartphone-derived digital biomarkers.
result Deep-learning models distinguish MS with 88% accuracy.
A conceptor-based approach helps robots recognize human internal states.
problem Recognizing human internal states for diagnostic purposes in autism therapy.
method A conceptor-based classifier to classify internal states.
result Initial results show potential for detailed diagnostic information.