A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.
Adaptive prediction timing improves healthcare outcomes by predicting patient events at the right frequency.
Study predicts when ALS patients will lose speech, swallowing, etc. based on covariates.
Modern treatments for Type 1 diabetes (T1D) use devices known as artificial pancreata (APs), which combine an insulin pump with a continuous glucose monitor (CGM) operating in a closed-loop manner to control blood glucose levels. In practice, poor performance of APs (frequent hyper- or hypoglycemic events) is common en…
Models for predicting the risk of cardiovascular events based on individual patient characteristics are important tools for managing patient care. Most current and commonly used risk prediction models have been built from carefully selected epidemiological cohorts. However, the homogeneity and limited size of such coho…
Synthetic medical data which preserves privacy while maintaining utility can be used as an alternative to real medical data, which has privacy costs and resource constraints associated with it. At present, most models focus on generating cross-sectional health data which is not necessarily representative of real data. …
New method identifies sepsis-related patient features in EMR data.
LMM predicts healthcare costs and risks with improved accuracy.
Enhances patient failure prediction using dynamic survival models.
Patients who suffer an acute coronary syndrome are at elevated risk for adverse cardiovascular events such as myocardial infarction and cardiovascular death. Accurate assessment of this risk is crucial to their course of care. We focus on estimating a patient's risk of cardiovascular death after an acute coronary syndr…
The availability of a large amount of electronic health records (EHR) provides huge opportunities to improve health care service by mining these data. One important application is clinical endpoint prediction, which aims to predict whether a disease, a symptom or an abnormal lab test will happen in the future according…
Framework improves clinical timeline reconstruction from text and tables.
Dynamic assessment of patient status (e.g. by an automated, continuously updated assessment of outcome) in the Intensive Care Unit (ICU) is of paramount importance for early alerting, decision support and resource allocation. Extraction and cleaning of expert-selected clinical variables discards information and protrac…
Bayesian method corrects timing misalignment in recurrent event studies.
Model predicts wound and episode-level readmission risk and time to re-admit.
SurvLatent ODE predicts VTE risk for cancer patients, outperforming current methods.
SurvCORN predicts survival curves using conditional ordinal ranking networks.
Cluster analysis aims at separating patients into phenotypically heterogenous groups and defining therapeutically homogeneous patient subclasses. It is an important approach in data-driven disease classification and subtyping. Acute coronary syndrome (ACS) is a syndrome due to sudden decrease of coronary artery blood f…
Study finds RNNs predict STBG better than ARIMA, useful for diabetes patients.
Predicts clinical events using a landmark approach with machine learning for large biomarker histories.
DDP models dynamic comorbidity networks from event data.
SurvFM-RMST converts survival outcomes into pseudo-observation targets for tabular models.
Ability to quantify and predict progression of a disease is fundamental for selecting an appropriate treatment. Many clinical metrics cannot be acquired frequently either because of their cost (e.g. MRI, gait analysis) or because they are inconvenient or harmful to a patient (e.g. biopsy, x-ray). In such scenarios, in …
Pharmaceutical targeting is one of key inputs for making sales and marketing strategy planning. Targeting list is built on predicting physician's sales potential of certain type of patient. In this paper, we present a time-sensitive targeting framework leveraging time series model to predict patient's disease and treat…
Bayesian model detects internal bleeding in ICU patients.
With the improvement of medical data capturing, vast amount of continuous patient monitoring data, e.g., electrocardiogram (ECG), real-time vital signs and medications, become available for clinical decision support at intensive care units (ICUs). However, it becomes increasingly challenging to model such data, due to …
Deep learning clusters patient time-series data for better prognosis.
An accurate model of patient-specific kidney graft survival distributions can help to improve shared-decision making in the treatment and care of patients. In this paper, we propose a deep learning method that directly models the survival function instead of estimating the hazard function to predict survival times for …
New algorithm predicts lung cancer progression and mortality.
Visual analytics system for comparing medical records using sequence embeddings.
Current clinical practice guidelines for managing Coronary Artery Disease (CAD) account for general cardiovascular risk factors. However, they do not present a framework that considers personalized patient-specific characteristics. Using the electronic health records of 21,460 patients, we created data-driven models fo…
Novel metrics improve machine learning models for ICU patient care.
25% of people who received a liver transplant will go on to develop diabetes within the next 5 years. These thousands of individuals are at 2-fold higher risk of cardiovascular events, graft loss, infections, as well as lower long-term survival. This is partly due to the medication used during and/or after transplant t…
Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative effectiveness research. One major carrier for conducting patient similarity resea…
Modeling disease progression in healthcare administrative databases is complicated by the fact that patients are observed only at irregular intervals when they seek healthcare services. In a longitudinal cohort of 76,888 patients with chronic obstructive pulmonary disease (COPD), we used a continuous-time hidden Markov…
Intensive care clinicians are presented with large quantities of patient information and measurements from a multitude of monitoring systems. The limited ability of humans to process such complex information hinders physicians to readily recognize and act on early signs of patient deterioration. We used machine learnin…
Imagine a patient in critical condition. What and when should be measured to forecast detrimental events, especially under the budget constraints? We answer this question by deep reinforcement learning (RL) that jointly minimizes the measurement cost and maximizes predictive gain, by scheduling strategically-timed meas…
Stratifying patients at risk for postoperative complications may facilitate timely and accurate workups and reduce the burden of adverse events on patients and the health system. Currently, a widely-used surgical risk calculator created by the American College of Surgeons, NSQIP, uses 21 preoperative covariates to asse…
Identifying patient characteristics that influence the rate of colorectal polyp recurrence can provide important insights into which patients are at higher risk for recurrence. We used natural language processing to extract polyp morphological characteristics from 953 polyp-presenting patients' electronic medical recor…
Clinical notes are a rich source of information about patient state. However, using them to predict clinical events with machine learning models is challenging. They are very high dimensional, sparse and have complex structure. Furthermore, training data is often scarce because it is expensive to obtain reliable labels…
Patients with epilepsy can manifest short, sub-clinical epileptic "bursts" in addition to full-blown clinical seizures. We believe the relationship between these two classes of events---something not previously studied quantitatively---could yield important insights into the nature and intrinsic dynamics of seizures. A…
Enhances understanding of patient healthcare journeys using self-attention.
Sepsis is a life-threatening condition that seriously endangers millions of people over the world. Hopefully, with the widespread availability of electronic health records (EHR), predictive models that can effectively deal with clinical sequential data increase the possibility to predict sepsis and take early preventiv…
Multivariate Bernoulli autoregressive (BAR) processes model time series of events in which the likelihood of current events is determined by the times and locations of past events. These processes can be used to model nonlinear dynamical systems corresponding to criminal activity, responses of patients to different med…
Preventing early progression of epilepsy and so the severity of seizures requires an effective diagnosis. Epileptic transients indicate the ability to develop seizures but humans overlook such brief events in an electroencephalogram (EEG) what compromises patient treatment. Traditionally, training of the EEG event dete…
New method uses surrogate outcomes and single-record data to improve suicide risk modeling.
Objective: A median of 14.4% of patient undergone at least one adverse event during surgery and a third of them are preventable. The occurrence of adverse events forces surgeons to implement corrective strategies and, thus, deviate from the standard surgical process. Therefore, it is clear that the automatic identifica…
Model predicts epileptic seizures with high accuracy using EEG signals.
Background. Real-world data show that approximately 50% of psoriasis patients treated with a biologic agent will discontinue the drug because of loss of efficacy. History of previous therapy with another biologic, female sex and obesity were identified as predictors of drug discontinuations, but their individual predic…