Paper simplifies balancing weights by relaxing outcome assumptions.
problem Estimating missing outcomes in a target population.
method Relaxes outcome assumptions to simplify balancing weights.
result Balancing weights can be simplified with convex loss and minimum worst-case bias.
A method corrects bias in estimating a high-dimensional classification rule using auxiliary outcomes.
problem Bias in estimating a high-dimensional classification rule using only one outcome.
method Robust transfer learning approach combining MTL and calibration steps.
result Final estimator achieves lower error than using only the target outcome.
Study uses surrogate data to improve treatment effect estimation with scarce outcome data.
problem Limited outcome data hinders estimating treatment effects.
method Uses abundant surrogate data to estimate treatment effects without stringent assumptions.
result Improves precision of treatment effect estimation.
Unified approach for estimating quantiles of potential outcomes using inverse estimating equations.
problem Estimating quantiles of potential outcomes for causal inference.
method Inverse estimating equations and moment function.
result Unified approach to estimate mean and quantiles of potential outcomes.
Paper proposes a method to estimate counterfactual outcomes without a known SCM.
problem Estimating counterfactual outcomes without a known structural causal model.
method Introduces rank preservation assumption and a novel ideal loss for unbiased learning of counterfactual outcomes.
result The proposed method is effective and unbiased, as shown by theoretical analysis and experiments.
CCN estimates full potential outcome distributions without restrictive assumptions.
problem Estimating CATE is insufficient; full potential outcome distributions provide greater insights.
method Collaborating Causal Networks (CCN) learns full potential outcome distributions without restrictive assumptions.
result CCN learns distributions that asymptotically capture true potential outcome distributions.
Two new estimators reduce costs and improve accuracy for EHR outcome prediction.
problem Sparse estimate distributions, high computational cost, and high sampling variance in EHR outcome prediction.
method Proposed SCOPE and REACH estimators that leverage next-token probability distributions.
result SCOPE and REACH match Monte Carlo accuracy with token reductions of 2.5-3.4 times and variance guarantees.
There is tremendous interest in precision medicine as a means to improve patient outcomes by tailoring treatment to individual characteristics. An individualized treatment rule formalizes precision medicine as a map from patient information to a recommended treatment. A treatment rule is defined to be optimal if it max…
Improved AutoDML estimator for causal inference using outcome-adapted shared covariate representation.
problem Efficiency in estimating treatment or policy effects in causal inference.
method Outcome-adapted AutoDML estimator that uses a shared covariate representation that is predictive of the outcome but not the Riesz representer.
result Outcome-adapted AutoDML estimator is asymptotically more efficient than baseline AutoDML.
The paper introduces metrics to rank potential outcomes for better decision-making.
problem Optimal action selection in uncertain situations using causal reasoning.
method Introducing two new metrics: probabilities of potential outcome ranking (PoR) and probability of achieving the best potential outcome (PoB). Establishing identification theorems and deriving bounds for these metrics, and presenting estimation methods.
result The estimators' finite-sample properties and their application to a real-world dataset are demonstrated.
Many estimators of the average effect of a treatment on an outcome require estimation of the propensity score, the outcome regression, or both. It is often beneficial to utilize flexible techniques such as semiparametric regression or machine learning to estimate these quantities. However, optimal estimation of these r…
Develops new methods to estimate treatment effects in survival data with competing risks.
problem Estimating treatment effects in survival data with competing risks.
method Censoring Unbiased Transformations (CUTs) for survival outcomes with and without competing risks.
result Consistent estimates of heterogeneous cumulative incidence effects and total effects using HTE learners.
Develops a Causal Transformer for estimating counterfactual outcomes from longitudinal data.
problem Estimating counterfactual outcomes over time from observational data is challenging due to complex, long-range dependencies.
method Combines three transformer subnetworks with separate inputs for time-varying covariates, previous treatments, and previous outcomes into a joint network with in-between cross-attentions. Uses a custom, end-to-end training procedure with a counterfactual domain confusion loss to address confounding bias.
result Achieves superior performance over current baselines in synthetic and real-world datasets.
DONUT improves treatment effect estimation by enforcing orthogonality constraints.
problem Estimating treatment effects from observational data is challenging due to unobserved outcomes.
method DONUT uses a regularization framework that formalizes unconfoundedness as orthogonality, leading to deep orthogonal networks.
result DONUT outperforms state-of-the-art methods in estimating average treatment effects.
The paper develops methods for causal inference from single-cell RNA sequencing data with multiple outcomes.
problem Causal inference from single-cell RNA sequencing data with multiple heterogeneous outcomes.
method Generic semiparametric inference framework for doubly robust estimation with multiple derived outcomes.
result Demonstrates the use of semiparametric inferential results for estimating causal effects in genomics.
Machine learning reduces variance in online experiment results.
problem Reducing variance in randomized controlled trials.
method Machine learning regression-adjusted treatment effect estimator (MLRATE).
result MLRATE reduces estimator variance by over 70% in A/A tests.
A fundamental challenge in semi-supervised learning lies in the observed data's disproportional size when compared with the size of the data collected with missing outcomes. An implicit understanding is that the dataset with missing outcomes, being significantly larger, ought to improve estimation and inference. Howeve…
Reduces variance in noisy social outcomes to improve policy evaluation and optimization.
problem Improving access to opportunity through personalized treatment decisions.
method Data-driven dimensionality-reduction using reduced rank regression to denoise multiple outcomes.
result Improves estimation error in policy evaluation and optimization, including on real-world data.
Flow IV uses IVs to infer counterfactuals in complex models.
problem Identifying causal effects and counterfactual reasoning in nonseparable outcome models.
method Utilizes instrumental variables and normalizing flows to estimate and infer counterfactual outcomes.
result Identifies a method to make causal inferences from observed data in nonseparable models.
New method identifies proxies for causal effects on multiple outcomes.
problem Estimating causal effects in scenarios with multiple outcomes and treatments.
method Causal discovery method leveraging multiple outcomes as proxies for each treatment effect.
result Parallel studies of multiple outcomes can assist in causal identification.
Proposes a deep learning framework for estimating counterfactual outcomes.
problem Challenges in estimating individual outcomes under different treatments.
method Deep variational Bayesian framework integrating factual and similar subjects' outcomes.
result Rigorously integrates individual features and similar subjects' responses for counterfactual outcomes.
Personalized medicine seeks to identify the causal effect of treatment for a particular patient as opposed to a clinical population at large. Most investigators estimate such personalized treatment effects by regressing the outcome of a randomized clinical trial (RCT) on patient covariates. The realized value of the ou…
Study clarifies variance of stratification estimators for causal effects.
problem Estimating average causal effects with discrete covariates.
method Combines insights from potential outcomes, causal diagrams, and structural models.
result Derives expressions for the variance of stratification estimators.
New method uses AI predictions as cheaper alternatives to expensive outcomes.
problem Using expensive outcomes for statistical inference.
method Recalibrated prediction-powered inference using machine learning techniques.
result Significant gains in effective sample size over existing PPI proposals.
Efficient RL method uses SSL for small labeled data in health outcomes.
problem Lack of precise health outcome data for reinforcement learning.
method Semi-supervised learning approach for Q-learning and value estimation.
result Method efficiently estimates Q-function and value function, robust to mis-specification.
A new method removes biases in data integration by using surrogate control outcomes.
problem Data integration methods can be biased due to data-dependent processes.
method Post-integrated inference method using surrogate control outcomes to account for latent heterogeneity.
result The method provides consistent and efficient estimators under minimal assumptions and potential misspecifications.
This paper proposes a method for estimating the effect of a policy intervention on an outcome over time. We train recurrent neural networks (RNNs) on the history of control unit outcomes to learn a useful representation for predicting future outcomes. The learned representation of control units is then applied to the t…
DEBIAS learns causal effects from psychiatric longitudinal data by optimizing outcome weights.
problem Causal inference challenges in psychiatric longitudinal data due to symptom heterogeneity and latent confounding.
method DEBIAS algorithm that optimizes outcome weights to maximize durable treatment effects and minimize confounding.
result DEBIAS consistently outperforms state-of-the-art methods in recovering causal effects for clinically interpretable composite outcomes.
Paper proposes Bayesian TMLE methods for causal effect uncertainty quantification.
problem Quantifying uncertainty in causal effect estimation.
method Three Bayesian TMLE approaches for binary and continuous outcomes.
result BN-TMLE outperforms classical implementations in small data regimes.
Fuses ITRs for primary and secondary outcomes to minimize harm.
problem Learn an ITR maximizing primary outcome while minimizing harm to secondary outcomes.
method Introduces fusion penalty to encourage similar recommendations for different outcomes. Two algorithms estimate the ITR using surrogate loss functions.
result Agreement rate between primary and secondary optimal ITRs converges faster than ignoring secondary outcomes.
Optimizes data labeling for causal effect estimation with missing outcomes.
problem Estimating causal effects with missing outcome data and budget constraints.
method Optimizes batch sampling probability to minimize variance of causal inference estimator.
result Achieves lower mean-squared error with fewer labeled data points.
Probit Monotone BART estimates binary outcomes using monotonic functions.
problem Estimating conditional mean functions for binary outcomes with monotonicity constraints.
method Proposes a new BART variant that incorporates monotonicity constraints for binary outcomes.
result Allows for more precise estimation of monotonic functions in binary outcome models.
Proposes a method to improve CATE estimation by imputing missing potential outcomes.
problem Statistical discrepancy between distinct treatment groups in CATE estimation.
method Contrastive learning approach to reliably impute missing potential outcomes for a subset of individuals.
result Improves the accuracy and robustness of CATE estimation models.
In this paper, we propose a robust method to estimate the average treatment effects in observational studies when the number of potential confounders is possibly much greater than the sample size. We first use a class of penalized M-estimators for the propensity score and outcome models. We then calibrate the initial e…
Estimates counterfactual outcomes linking observed and unobserved data.
problem Estimating expected counterfactual outcomes for individuals.
method Introduces retrospective counterfactual estimators and prediction intervals linking observed and unobserved outcomes.
result Retrospective counterfactual estimators and prediction intervals asymptotically satisfy valid coverage under standard causal assumptions.
New framework estimates long-term outcomes from short-term data.
problem Estimating long-term outcomes from short-term data.
method Reward function decomposition-based framework (LOPE).
result LOPE outperforms existing methods, especially when surrogacy is violated.
Paper introduces GDR-learners for estimating potential outcomes from observational data.
problem Lack of theoretical property of general Neyman-orthogonality in deep generative models.
method Develops flexible GDR-learners based on various deep generative models.
result GDR-learners possess quasi-oracle efficiency and rate double robustness, asymptotically optimal.
New algorithms optimize decision rules in strategic scenarios, minimizing prediction risk and incentivizing better outcomes.
problem Strategic agents manipulate features to improve outcomes, complicating decision-making models.
method Efficient algorithms for learning decision rules that minimize prediction risk, incentivize better outcomes, and estimate true model coefficients.
result Optimal decision rules can be learned through testing and observing agent responses, circumventing hardness results.
Two-stage TMLE reduces bias and improves efficiency in CRTs.
problem Differential outcome measurement and imbalance in baseline predictors in CRTs.
method Two-stage targeted minimum loss-based estimator (TMLE) to adjust for baseline covariates.
result Our approach nearly eliminates bias due to differential outcome measurement.
Estimation of individual treatment effects is commonly used as the basis for contextual decision making in fields such as healthcare, education, and economics. However, it is often sufficient for the decision maker to have estimates of upper and lower bounds on the potential outcomes of decision alternatives to assess …
Optimizes treatment duration to maximize quality-adjusted lifetime.
problem Balancing risks and benefits in clinical decision making.
method Proposes a weighted estimating equation to adjust for confounding and informative censoring, and a nonparametric estimator for mean counterfactual quality-adjusted lifetime.
result Shows the optimal time for percutaneous endoscopic gastrostomy insertion in ALS patients.
Novel characterization of augmented balancing weights combining outcome and weighting models.
problem Improving estimation accuracy in machine learning models with balancing weights.
method Characterization of augmented balancing weights as linear models, extending to ridge and lasso regression.
result Equivalence and closed-form expressions for specific model choices, providing insights into performance.
PEER tackles multi-response regression with incomplete outcomes efficiently.
problem Challenges in estimating, predicting, and computing with large-scale multi-response regression and incomplete outcomes.
method PEER converts multi-response regression into parallel univariate-response regressions.
result PEER achieves consistency in estimation, prediction, and variable selection.
FOCaL meta-learner estimates functional treatment effects robustly.
problem Estimating heterogeneous treatment effects from functional outcomes.
method Doubly robust meta-learner FOCaL integrating functional regression.
result Direct and robust estimation of F-CATE.
The study uses transfer learning to compare surgical outcomes across racial/ethnic subgroups.
problem Difficulty in comparing surgical outcomes due to racial/ethnic and geographic differences.
method Causal inference framework and transfer learning to incorporate data from multiple populations.
result Racial and ethnic differences in surgical outcomes are found, with non-Hispanic Black patients experiencing wide variability.
GraphITE estimates individual effects of graph-structured treatments.
problem Estimating individual effects of complex treatment structures.
method Graph neural networks and Hilbert-Schmidt Independence Criterion regularization.
result GraphITE outperforms baselines in estimating treatment effects for large numbers of treatments.
A new method generates counterfactual treatment outcomes for time-varying treatments.
problem Estimating counterfactual outcomes for time-varying treatments with high-dimensional outcomes.
method Conditional generative framework with inverse probability re-weighting.
result Our method outperforms state-of-the-art baselines in generating high-quality counterfactual samples.
Estimates and tests treatment effects on entire outcome distributions.
problem Treatment effects on entire outcome distributions, not just averages.
method Proposes a novel estimand and doubly robust estimator, develops a test.
result First test with provably valid type 1 error guarantees in this setting.